Clinical and paraclinical manifestations of hospitalized patients with COVID-19 in a selected teaching and medical center of Qazvin University of Medical Sciences: A cross-sectional studyCovid-19, Laboratory manifestations, clinical manifestationsYekefallah L, Moradi M, Mohammadi SCovid-19, Laboratory manifestations, clinical manifestationsK1352026-07-30T05:55:00Z2026-07-30T05:56:00Z2026-07-30T06:00:00Z171120263852Paperfatemeh ValizadehLorestan university of Medical sciencesURL of paper abstract532149749051611111100055824

Caring Today, Volume 18, Issue 1, 2025

Journal homepage: https://caringtoday.lums.ac.ir

Online ISSN

2783-

185X

/9j/4AAQSkZJRgABAQEA3ADcAAD/2wBDAAIBAQEBAQIBAQECAgICAgQDAgICAgUEBAMEBgUGBgYF BgYGBwkIBgcJBwYGCAsICQoKCgoKBggLDAsKDAkKCgr/2wBDAQICAgICAgUDAwUKBwYHCgoKCgoK CgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgr/wAARCAD1AQEDASIA AhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQA AAF9AQIDAAQRBRIhMUEGE1FhByJxFDKBkaEII0KxwRVS0fAkM2JyggkKFhcYGRolJicoKSo0NTY3 ODk6Q0RFRkdISUpTVFVWV1hZWmNkZWZnaGlqc3R1dnd4eXqDhIWGh4iJipKTlJWWl5iZmqKjpKWm p6ipqrKztLW2t7i5usLDxMXGx8jJytLT1NXW19jZ2uHi4+Tl5ufo6erx8vP09fb3+Pn6/8QAHwEA AwEBAQEBAQEBAQAAAAAAAAECAwQFBgcICQoL/8QAtREAAgECBAQDBAcFBAQAAQJ3AAECAxEEBSEx BhJBUQdhcRMiMoEIFEKRobHBCSMzUvAVYnLRChYkNOEl8RcYGRomJygpKjU2Nzg5OkNERUZHSElK U1RVVldYWVpjZGVmZ2hpanN0dXZ3eHl6goOEhYaHiImKkpOUlZaXmJmaoqOkpaanqKmqsrO0tba3 uLm6wsPExcbHyMnK0tPU1dbX2Nna4uPk5ebn6Onq8vP09fb3+Pn6/9oADAMBAAIRAxEAPwD9/KKK KACiiigAooooAKKKKACiiigAooooAKKKKACiiigAooooAKKKKACiiigAooooAKKKKACiiigAoooo AKKKKACiiigAooooAKKKKACiiigAooooAKKKKACiiigAooooAKKM460Ag9KACiijPegAoopNy+tA C0UUZx1oAKKKKACiiigAooooAKKKKACiiigAooooAKKKKACiiigAooooAKKKKACiiigAooyOlNdt ozQA7NG4etRs+ByajmnjhXez8UXDcm3DvSZA/wDrVxPj/wCPvwh+GNo9345+IOmafHGoLm4u1UjJ wD19a8D+IX/BXz9k/wAHPJbaNrt9rU0Nx5Lx6daM3/AsthSo9QTntmuWrjcLQV6k0vVo9/LOFeIs 4/3PCzn6RdvvPrIsR1P60Z2rya/Pvxl/wXR8H6fdKvgj4P6hqUbH5murpYMfh81Yz/8ABeOdk3D9 n6Xd/d/thf8A4mvNlxHk8ZWdVfj/AJH19Lwb8Rq1NTjgJWfey/Bu5+jmSec0NhTXwP4M/wCC5fwz vrPzfHPwv1fT5N3yxWciT7h9SVr174e/8FWP2RPH0kVtL8QP7LuJLfzDDqkLReXjGQzfdyM9M8/h XTRznLa3wVY/fY8jMvDfjbK03iMDUSW7UW196ufTm80BgeDXK+Dvi38PfHdjHqHg/wAYWOoRTRo8 clvdK+5WXKnr3rplmWWNXQ16MZQmrxZ8bWw9fDy5KkXF+asTUVCSzDO6pI2+TJNO5kOooopgFFFF ABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUEgDJozTZWG3FADSwxkCmTXEaRbnaqWta7pfh /T31TWLtLe3jXdJLI21VHrX52ft4/wDBWPUo9Rn+Fv7NGooPJ3JqfiIgOAcY2QjoWzyWORxgA5JH n5hmOFy6i6lWVvzfofWcI8F59xpmKwuX0m+7+zFd2z6u/ac/b1+Av7M2myL4q8Srdat5bvb6Jp7C SecjAxjPy8kDLEAd8Cvzy/aJ/wCCtX7RXxemm0nwAyeFdJaRlj+xvuunUE7Sz44yNpIAGDkZI5Py 7qup6pr+pTarreo3F1d3ErSTXFzM0ju7OWJJYk5JYk5NRgtv2mvzfMuKsdi5OFF8sfLf7z+2OBfo /wDDPDtONbMksRW31+Fei6/Mu+IfE/iXxbetqPifXbzUJ5PvTXVwzt1zjk+tUVi2DGacc55FHIHL V8xUrVKkrzbf4n7th8Dg8FTUKEIxilaySS/AagxxQpbdytKGB+Uj2ozg5NR9k7Buw/xGmmMsMFac pJXkinIy4zRHQUqcZaSX6mv4J+InxA+HWpR6z4I8Yajpk8bArJZ3LLkgEAkA4OATxX1n+zh/wWP+ MXw9uYdE+Numr4l0vzAsl5AojuoV4GeyuB+BJJ5OMV8b4x8oFNcn7pFelgs4x+XyTpzduz1X3Hw3 E3hvwlxXQcMbho8z2lFWkvO6P3R/Z7/a/wDgd+0loa6p8NvGlvPIqg3FjN+7uIcjgMjYIP4V6nHI rR/er+efwn4w8WeAdet/FHgbxFdaXqFvIrR3VnKVbg5A64P0OQRxg8iv0o/YU/4KxaV8S9QtfhV+ 0CINL1p1Edlq6Ntt7xgMYbP+rc4PHQ9j2H6Fk/FGHx1oV/dn07M/jnxI8B844VjPGZZetQWrVvei vRbo+9kkUrTtw9apWt7bXVv50E4dW+6ynrU6Nlc5r66PvbH89NOLsyaiiigQUUUUAFFFFABRRRQA UUUUAFFFFABRRRQAUMcDNFNkJ2dKAGM5XpWfr3iDTdA0q41fVrtILe3jMk0jtgKoHJJq1cTrFHvZ ugr8zv8AgrL+3Xc+IdWuP2bfhXrLx2tqyjxFeWsxBaTqLfI7YILc47etefmWYUctwsqs3tt5s+w4 J4OzHjbPqeX4VaN+9LpGPVv9PM4n/goV/wAFI/EXx21S7+FnwjvprHwzbyMl1eRsVkviDjj0T9TX yGy5zJ/e596QepHP+z9KXHy4r8dzLMq+ZYh1Kj9F0P8ASjg3gzKeC8phgsFBK3xS6yfdsOFbeBRv CjcaaX9ucjivpT9kr/gmd8ZP2kJ49c8TWk/hvw7uVvt11D+8uFJBPlqfQdzxzWeDwGKx1TkpRbZ0 cS8X5FwngZYnMqqgl0vq/JLds+dLGyv9WvF0/SrCa5mdtqQwRlmY+wFez/C//gnr+1P8WY47jR/h 1cWNvI6ZudQPlgKwzvweSAOvFfpt8L/2T/2Tv2OPDP8Aa0umadbyQR/6RrWsSKZWb1LN357AV5r8 YP8AgsP+zn8NLr+xfAem3XiGaNgrNYRhYlGDzuPBwccD1r66nwzl+DpqeOqrXotD+ccd45cX8T4q WH4UwEpLpKSb+fZfeeB+EP8Agh38YdW01pPFnxM03T7jzP3ccMLSrt9T0/KtZf8AghH48Lf8lysv /BY3H61zvjj/AILa/HnWDGPBHgjR9J2yHzftG6fcvIHTbg9D37isX/h83+1fjH2LQOD83+iNz7/e q3W4Qpvls395jHBfSQxv772kYX6XirfgzqPGP/BED4w6VZLL4R+JOm6hLu/eJNC0Q2+oPP5V4T8U f+Cff7U3wmie71r4bXV5bRrIxutOHmjaoznA6ZHTPWvZvBf/AAWx/aA0h5G8a+CtF1SNmXyVtd8G xe+Tls/pX0D8JP8Agsf+zp4/m/sn4h6Rd+H5C23ddRiSJuBzlc9+Bn0q/qnCuO0pz5W9tbfmD4m8 feEv3mPwyrwW9knp6x/yPy0vrW/0y+k07VLGW3uIWKyQzRlWVh1GPWoi/wAu41+zHxN/ZR/ZA/bX 8JPrVjY6bcTTq5tde0OZVmjY7hncvXDEnDDBIzg4r8+P2vP+CaXxh/ZrkufFegxN4g8MiX5bq1jJ lt14/wBav4n5hx37142ZcMYvBxdSl78N7rt6H6JwT47cP8R11gswi8NX2tLZvsn38nY+a+hyRS4Y SCSNirKwwV459Qf8/pSBwo2enH0o3BuQK+ZjKVOWm5+4uNLEUbNXi116o+6v+Ccf/BTjWPBWo2fw O+P2pSXml3EixaPr1xJmS29I5j3XjAbqOAc9a/Taw1O3v7OO8tXWSORdyMhzmv54QzBsq3P8J9K/ Rz/gkz+3rP4ggtv2a/irqpe9t4yPD+oXU2WuI858pif4gOnqPcV+h8M8QOrbDYh69H+jP4y8cvB2 nl8Z57k8LRvepBbL+9FfmvmfofvPrSpJkc1CkwMYJFTIFIxX32nKfyWOooooAKKKKACiiigAoooo AKKKKACiiigAqORyFyacXw2M1XvbmOC2edj8qrn8qBxjzOx86f8ABSH9rCH9mL4F3U2i3ir4i1pW stDj25xIVJMhHdUXk++B3FfjPdXF5f3D3+o3kk9xOxkmmmcszMTkkk8kkknk+te6/wDBRz9pG4/a L/aU1aazvWk0Xw7M+m6Iu/5SqNiWYf77g891RPTnwdtmOK/IuJs0ljsc4Rfux0Xqt2f6I+BfAtLh XhaGLrRtXr2k31StpHy0evmO+8Mim7pCfKQbmY/KvqfSjdX2t/wSc/Ybt/jBro/aB+KejLJoOl3D Jotjcx5W7nUgGUg8FVII54JHcDnysry+rmeKjSj169kfoPHfGeX8EZDUzDEvVfDHrKT2S+f4HXf8 E7/+CWH2s2Pxv/aN0sFIwk+j+HLle+Ayyzg/mEPHrkcH6B/bB/4KIfCX9lDTT4J0GOHU/ES2+IdL tCAkAA+UyEfd+nU1gf8ABSP9vjTP2bvCknwt+HN6jeLtQtP3Pl4YWMZ48x/frgHrjPSvyh1bVdW1 7VbjXdd1Se9vLyVpbq5uZC7ySMcliT7/AJD04FfZ4/NMNw/h1hcIk59X5935n8xcH8D594wZs+IO I5tYbm92Gquuy7L8Wdz8df2ofjT+0f4hk1/4neMZ7iMnFvpsMjJbQLnICoDgkf3jkn26VwCoG+8K ChI3UqgA818FXxWIxU3OrJyb7n9dZPkWU5DhY4bA0owiukVb/h2OEaB+BQFjAxtpGdT3o3qG+8Py rn16I9YXYo4DUxkCtgEf4U7IPQ0NtJ5FHvEy5XHVXOy+Cf7Q3xk/Z68RJ4i+FHjW609tw860Zy9v cLuB2vGTjGQORg44z1r9Mv2Ov+ClPw2/am05vh78TtPt9G8QMuw2c7hobxcdUJ698g81+TJdg2B+ dSWN7f6XfQ6npl5Jb3FvKskM8TFWRgcggivoMpz/ABeX1FGUnKHVPp6H5Hx94QcO8YYd1qcFRxC1 jOKs79L23/M/QH/got/wTGsbawvfjt+z5pm0JGbjVtCt1+Vl6mWIDv6rjBr8+gGViroVbOCrcYr9 Mv8Agmv/AMFGF+Lnl/Ar413KDWlh22GoSEKl6APunP8AHjt3HSvJf+Crf7Df/Cr9Zk/aG+Fuj7dD vpv+J5Z26gLZSNjbIB2V24PoT717WcZZh8xwv9oYLXul/kfm/hvx3nnCGff6pcTt9qVR9eyu90+n 3M+KQozmrHh7X9Z8J67Z+JfD17Ja3thcpNb3EbEMjqc54I/EenFVY2+XLihvYV8TTqSpz5ouzR/T uKw+Hx+FlRqxUoSTTT2aZ+3X7DX7T2l/tP8AwS03xglwq6nbxrBrFuMZinUYbj07j2Ne3xnC7s1+ NX/BLr9pq6+An7Qdr4X1XUCuh+Kpks7lWb5Irg58uT8T8p9civ2Rs7iO4tUkTneuVr9myPM45ll8 Z/aWj9T/ADQ8WOCanBXFdXDRX7qfvQfk+nyLNFG4etFe0fmIUUUUAFFFFABRRRQAUUUUAFB6c03e aGddvJoAi3HOCPmrz39pbxRb+Gvgp4ivl8e6f4bmbSLlbXWtSmCRWcnktiU567MF9vUhTXJfty/t wfDD9hv4O3HxN8ezme8mYw6Jo8bDzb2425VB6KP4m7Cvxn134h/t3f8ABZn4qXmjxeIIbTQdFWS6 nSa6NvpekQsSm+U9HYKcDPJG7GOa97K+H6mYUZV68lTpR3k/07s+dzLib+zcXTw+Eg6tdtcsVr9/ keg6r4s/4JY/C6+PhTxZ8WfFHiy+ilkW51Dw9bhLeN438tkG774JUsGHBUitO2+DX7M37S3w71rx 9+xR4/v7vUvDVt9p1rwlry7bv7OCczJj73Tt079a7T9mz/gm9/wTtv8AWdW8KarJ4h8cW/huykm8 X/ED7ULTSNPYWuTEhPEhLZYc8fNnpz4j/wAEbdF0eD/goJ4u8aeCEuLrwL4e0HxBNNdSMVxpriRb YyqfvEgqMHvzWOJ4P4KzHKcRUwalemr8zVk35M/Qsp8ZfGLhzi3B08wrXjUkl7Le0XbddNCl+z78 H9b+Pvxf0H4X6JC+7VbpRcyKufJgHLufTAH0yR61+v8A8Z/iJ4A/YM/ZXW40u2hhh0vT1s9FsV+X zrjbhF9zwWJ9FJr5j/4I2fCTQvEfjfxv+0dHprJbtqUlnoIkh2hIS5d9n4FVPoVry/8A4LF/tEXP xJ+PEXwa0i7b+yfCcS/aFSTKy3kgDMeODsXC4PIO/wBa/KsHTp5DlE8RpzSbs/wX+Z/SnE2Kxni1 4lYXJldUKKUprpeycvzSXzPlb4geOvE/xP8AHGqfETxlqT3epardNPdSOx6lshVB6KBgAdgKyVQH lWpOR1NNLJnIb9a/P6lSpiKrk9ZM/sLB4XB5RgY0KSUIQikktEkhzPt74rN8DXHjL4xfFZPg38Ff Blx4k1xbdri8ht2Cx20YUnc7nheRgZ6k4rpv2cP2cfin+3D8RrjwX4DuG0bwfo90sfinxWeWzjLW 9v8A3nbpnoOtfp9+zF+yF8EP2SfCz+G/hP4VSCa7YPqmrz/PdXrjGC8nUgcgL0GT6kn3cLltKilP EK91pG9n6s/nnxD8ZK2FxEsDkTV4u0qlrq/VL9WfPv7C3/BM74XftR/DO1+Kmq/FC5b7PqVzp+u6 FDCI59NvYflms5weUljYjI9CD3r6Gf8A4Io/sx+bn+29b+n2wf4V8I/DP9vP40fs5fEH46fDL4P6 PYaPZ3nx98R6i9w0XmSSXHnLbyuO2JPs6ye289q3G/4Kg/thm8F8fiGud2dn2YbT7Yr6KpiuGcDJ UpUtbK+l7aLqfB5VknjhxlhVmdDHOFOabj71r622SPpj4lf8EPvDkrzXvww+I9xC3y+Va30e9V9e RXyD+0Z+xB+0D+zW8mpeM/CklxpUalm1axUvDGBjlv7vXvx19K9y+Bn/AAWO/aB0rxBY+H/HPhe3 8TG8ukhjjs4/LuJGZwAFA4J5wB3OK+3Pi1+2V+yp4H8JWOj/ALTXj/w74duNctSl34d1y7jkljLR AtFIgzj5WGcjBB4rsw2R5RxHTf1OLUl0V9/NHm4/xI8T/CLHwpcQ1I1acv5mm2utn/mj8URIpHXJ 71ueFPhn8RvH1vcXngjwRqWqw2o/0iaxtWdY+O5HtXtXjf41f8EXf+Ej1TxjoHiXxhcwyO3k+HbP TXhjVgxyY3f+E549hXmvxY/4K8N4bPhH4f8A7Euhal4F8G6Dcrc6wt0kUl3qknmZKyMB8ybeMdTk DsK6sq8I+IMbWcasXCKv7z6nocVfTK4Ny3L4Ty2DqVm1dN7X323scXZ3uueGdch1CwnmsNR026jk jkAKSQyIQR9Dx/Q1+u37F3x/8G/t5fs033gnx/bw3WpxWJsPEljIPvblIWT2DDJB7EH0r4C+IP8A wUa/4JdfFjxHL458d/s++MG1m8hUalJp80cMTyqPmcKPU19F/wDBJL4r/sW/Fb4qeKNY/Zo0PxZ4 buNF0lJdYh1y8WS3urd356cKUKryezHHeu3A8D8RcPynOtG9F6N7L1PgeOfHTgDxNy6gsPGVPHQt KL892r777Hxf+0/8Dta/Zx+Ouu/CPWN7rY3HmafcMuPtFq/Mcg9ePlP+0relcISF+YHiv0s/4LYf s+2+ufDfSv2hNB01ftmhXC2mqyRr8z2krgKTxk7ZNvHQCRzXxx4I+Avwb8C/A+1/aK/bC+Jd14T8 O6xfNaeG7OysmmvdRIHMiRjkpwTn0Br4XGcM47EZ08NhIOV9Vbs/8j+kuEfGjh3C+HlHNc6rqEof u5X3cklql5rX5njMUs0E8d3aXLwzQsHjkjbDI2cgg+oIHPav27/YJ+Pf/DQ37NXh/wAbXE+7UEtf suqKeq3EWUc+wLDI9QQa/JD9oz9nzTvhNa+H/iH8PvF8fiLwP4y00XvhjWo4ypkXujA9GHf8a+rv +CGXxeWy8V+LPgjqF0qreRR6vp8XO5yNsMx9gP3H5mu3hv6xlObSwVdcrfR90fLeN1PJ+PfD2lxH lkudU3dSt9luzT9D9Mh0qQHIzTV5jxTtw9a/SD+IgooooAKKKKACiiigAooooAjbbjg1x3xw+MHg /wCA/wAK9b+LfjzUFtdL0OxkubmRuMqBwo9Sx4HvXYuVA3V+Vf8Awch/tOap4e8H+E/2YvD16Y11 15NU1zypOTBEQscbD0LHcPXbXp5Pl8szzCnh11evp1PFz/NI5RldTEPtp69D4x8deNP2gv8AgsX+ 2n/ZFhdzpZz3DNZWM0x+zaPpqN88mOgIU7iTyx4r1j40fFP4afDL4fp+yp+ynFNpvhGxnL+JNYzt uPEd2BhpJW6mJTnC9MY7dfoL/glT+ytZfAP/AIJs+Nf2lr+FYvEnjbwrfXFnfL9+3slhk8nae2T8 x98V8H/Br4W/GD9tX4px/DD4OadcQ+H47kjxV4ydCIbSMYLoh/ikYcADnPPQVzeJGdYqtKGV4L3K MNJNaLTds/TPo8ZPwvlOHr8T8QL2mI09nF63crvReX4H1N8J/AWn/wDBQ79jbRf2UfgJ+0XY+D9Q 8HapfN8SvD0kZUat9omeS3kZ1/1gVUYEZIPQ/dAr0jxP/wAE+PiV+zt+x5P+z5+x54q0WfxBrUrP 408QalCY7jUVyMW0bj7kYOep5Ne4fsl/sbfCL9mPwuPA/wAJPDkNq8irJq2sXWDNPhSN8kh7DLH8 TXi/7UH/AAWS+DnwR8dXnwa/Z4+H8/xA8RWTeTNqUWWtBcAHKIFBMmO5HBzx0rx8nrcRZ5l6y3BR /drdvRPTqeTxNjOHcp4onn2Jly1pycox3tdtpJMsfsQftv8Ah/8AYV+Hb/sz/tdfDvUvA+rRC+u7 PxJMDNpmpuB5hEco4ViOinuK+IPHPjab4j+NtY+IV5drcTa1qU93NNH91mdi2fxzX35+yv8Atgfs zf8ABVXwrqfwh8YfDSzsPF9rDIbrwtqKiSO6gxskmiYj5SueRwRxXh3i/wCE3/BMj4P/ALQV7+wH JqmvadeNZzT6h45m1RTBpFxDYm58rJ7KkRBH97A715+acI55mElguS0qer00ttc/SPDHxo4X4Nx1 bN8Zeo69lzaXTvdp+r/I+XxNF5iwCaNWd9i7mABPTFfSnxi8R/sd/wDBO+fw38J/jp8HNQ8a+M9d 0GG98RRxzbUsLe4yuyMfxScMFxzkVk/s/wDhr/gjb8Q/jTJ4PHiDxheNpPh+41B9f124ZLC7MFos 80uwfcYKsh54BjIHUV7p+z9+1X+w7/wUD+LHir4/fF34C/Y3+FekJdW/ijVW3w3FlDIwj3jp5mWD Be+T6V6HDPAv9lYidXH0XNJfc3t+Jj4tfSMxfGmEp4TJK3sI83vWeskt726JXPon4P8AwO+DnwC+ G+jeFvgX4SXR/D95psN/b2cinzz56CQmUnkv83Oec1gftZ/tG+E/2UfgJ4h+Nviu5j/4ldmw0uzl fH22+KN5FsPd3ABx0GT2rkv2cv8Agqh+zr+1X/wsDxF4j0tvBug+B44ZYtdv5x5d7AzFEUL2f5eE HPK189/tA/DD4U/8FaNQutH/AGcf2ptQ8Sah4QnXWk8A6hY/Zre4ti0iZX+86syjd2yB/FXnZhwl mlPHzrVKbVOOu3zS9T4XI+LMox9Ohh3XXNN2bbtu9ZfI+I/gTpOq6V4Ag1XxFqNxdalrMz6nqVxd yl3lmmwdxJ53FdpOf4t3euzaXnk9a93+IOn/ALFv7CrXHhn446w3xC8f28kccng/QpMW9ixjLbJX H8WSOOo+X3q34H/aw/YX/aP8aWHwF+J37O1x8MLrVIVg0LxCZGHlSuf3QkBGdrn+LvXly8OeJcyo zxvJZO7S623P6iwH0mPDXhGeGyCk5TjDlg5q1k9E39+p5P8AAz4jw/CP4xeG/iXd6THew6RqaTTW 0i7lZe5x6gEsPcCvUPjb8C/+Ccnxr+OXiD9p7xv+0L4iuI/El8+o6h4TtLMtdRzSjHlqx/hQ9B0C jHavLvjh8HPFnwC+KGqfC7xpFtutPmISUD5Zoz9yRfUMOfrXa/sV/BDQvjD8V5Nc+IE4tfBXg3T5 Nc8ZajJxHFZwqXKMe27a3H91WryuFM5zzI8weDwa96T5dtU9mfVeMXBXh7x7w7HiXM6rdOlByTi9 GrXS9dSn/wAFE/2ef2Cv2V/2V/Cek/DDwVrd3468cWi3+lXOuXBS4srAkHzpox0LA7UU9TuP8Jrc /ZA/Zm+GX7KP7FjftgftHfBS18Xar42vI7TwpoOqwnyYLXPE7/3S20kZ/hHH3q4v4IeC/F//AAWD /wCCm174o8SW80PhOyvDd30ef3en6LbSBLe1TsCyhV/3nduxr7Y/4KRf8FKf2Ofg5p1v+yhJ8OI/ HMmnrbpcaNpsoS3sxEwCxBl/jAH3R0xg1/RmbTzv+y45ZhZuWIkuaTvtfZeR/mXw7LhGHFDzbMKK WDhPljD+ZJ6+rsfMq/tW/svs3m/8MAeA/O6nAk646daj8U/tuabb/DTXvh18DfgNoHw9j8TRxQa9 eeH2ZZLmBN2EJ685K/R2ra+Ddl+zF/wUU0rxB8OvgH8MJPAHxG0G3+26fpN5eFo9QhDASDkZDKOu emR61k/E7Vv2JP2GYB4O+KkU3xO+IPlSC+0fRrjbZWDb0Bidx/HjeR7qfUV+P1sn8Q62OeAnUctN ddLM/srL+LPo05fkcM6pYRRqJ2UN5XXU/SL4GeP/AAn+1z+wTZ6/8WrxGsdW8NzWviS4kwgWSINF PJ/sjcjMPYg1+RvxG1Txd/wVr/bvtfhf8MJJNP8Ah74fAtNHjViLbTNGtzte5I6BnXkE84Kjsa6j 4/f8FVfBuvfscX37JX7Nnwk1XwTe6/rDR6xbPdFwtq4HmJGfvBpNoUjsGbua9k+CWh/sx/8ABKf9 i8v+0lf3j/ED4nWUcuoaNo7gX8NoQGW3z1jXBG/PVjjtX6lk+T4zIcvdWpC+JkuWK+Wr9D+S+JOJ Mp4mz6WHw1VwwCm5yXk3ord7WR5f+2V8Y/CHifxDpPwR+EkYh8DfDuy/snw6qtnztnyvNn3bNaH/ AATV+Isnw8/bO8G6g2pJa2uqTS6bes//AC0WWJvLj/GdYcVD8Jv2zf2APi58StF+Fni39labwjZ+ Irr7KviS41Bj9maQ7UlIPUFsc9BnNd1rXwG+CX/BOfWIfjt+1v4ya+a08TJN4C8N6E6tc6mlvcLI l4R2T5Q3pj3NfkeP4N4opcQ08RWhzSnLm07X/wAj+zMk8bPCvE+FuJyOg3TjSp8iva8pNb/Nn7AQ ymSNG/vLUmQE5rwE/t9/BXTv2MLX9tfVZ7ux8LTaUbqGC+iMdw7bzEsIU9XaQbR2bIYcGtD9if8A bd+G37cvw3vviP8ADPTNQtbWx1I2c0WoxbWL7Q2QRwQQfwr66WDxUaTqODsnZvpfsfyqswwVTEKl Ga5mrpd13PcqKjyT1NSVznYFFFFABRRRQAUUU1zhaAIwQUY561+D3/BxJBer+37HPcRTLbyeB9P+ ztID5bESXG7b69Vz+FfuH8RPiL4L+Fngy/8AH3j3xBa6XpOm27TXl5eTBERQM9+5xjFflH8RPE3w 7/4Ly3Xi7QPDHhmTwjq3gC93eBPGFxGWtdUs2wGgmbja7MFYL2HXoc/QcLZlh8pzWNau7Raav2v1 PmeLMnxWdZS6WHV5Jp2726HpHj/Xv2iP2p/2J/hH8BP2LYrXSfA/ijwylp428ZWciSNpsccYR7Py h8ys/wA3174xz7F8I/gr8Fv2C/2fbPwv4i8WaV4T8N+H9PabUNY1edI5rohC8kzAfNI7BHbABJxg DtX5r+Cf+CeP/BX74CG+8OfCPRdfsLJblnb+w9eRbe6bGPMUbhkehwCeter/AA6/4I4/tSfG/UrX xr+3v+0VcWOnRwxE6Q2pNe3zjDHZ12RsrtjoThmxTzrh7I8RiJYmvjY+yu3Zat63tYjIeJuIsPhY 4PD4KXtEkk2rJO1rmb/wUH/4LI6P8RvCWs/sz/slaZd2mm6pdJaal40upvKmvIeNwhA5SNmJXcTk qM8bqpah8S/2a/8Aglf8ALLwr8OrbR/HHxy8TaWs+r61DMl1b6AXU52uMgspyoA5JUk4FfTPxT/4 JG/sK/FX4V+H/AHhkal4JuvDckgi1y1QTXGoI4UEz5+8x2hufukt60/4Q/8ABI39ij4ZeAPEnw61 e/1TxJfeK9NktZPFV5Gok01GHHkr0Vg3Jbr+dd+D4j4LwOBpUqE3GKlqlvLVWu+3Wx52O4V46x+Y Va2IgpSlH3W9o3Wtl+p8y/8ABIbw/wCG/wBmv4WfED/gpx8XNYWE2tpeab4ZsZZAv9o3cjbpMDOT mXauB0wxrhP+Cdn7F9//AMFKP2gPGP7RH7QGoXcfhDTNWa88R3MHyvqV7O2/7Ip91PzkdmUfxV9V XH/BEH4K33wku/hfYftTeJLsxxvJ4bh1KPbZafds2WmaJMbyw49uor6M/Zk/Z28Dfshfs5aL+zt4 E1Bb5rWRr3xFrKR7TqN8/V8f3R0APRVUdqnOONsrweFr4jCVearOyXTliiMj4BznFYuhh8ZStSg2 3r8Umz4e/wCCz/w2/Zy/ZxtPCXwx/Zx+Gdjo3ij4jabt1WSzm+aHTFlTyo9nYzSkZYdVhdTwSK5P 9v8A8M6T/wAE+P2J/A/7EfhcIvivxtCuu/Ea+hlHmOUxttzjnaHbaOxCN619ifta/sUeA/jx+2H8 IP2tta+Mun6E3htdM0rVNJ1WxL2939lupbmNVbO1DIZJVy2QT5Y6mr37eX/BHPVP22f2u9H+Pmo/ FG00/wAO2+l2VpqGkraM800cMruwV87QGD4zj1rqyXiLAVqOGdapdRTlLreXRfLc4894XzGniMQq FPlbajG3SPVn55/s8fsOeJbv9gnx3+1b8cdQ1LT/AATpdjLN4e0OzPlyapfMVhjuXJ6xo7Lgdwpr pP2C/EmnfsLfsS/ET9ui+u7O38b+LoW8L/DO3mkHmunmj7TcIAclVZS3IxutFH8Yz+vn7S/7H/hD 49/sn6r+yrpdz/YWm3mlxWlnNZxj/RRGyFML0I+TBHvXwvp//BCz9n34OfCfUZf2uv2npplhs2tt BuvtH2a00gySs+9I3PzMZGBIPBr0qfEmFzOlOOJk/emvdSv7qs7L16s8rEcL47K505YZL3YP3m7J Sf8AWh4X/wAE/wD4e/stfBP4NXf/AAUg/bm8V2mua14g1K9k8G+HrydZ5r6aF3SSZo+SZGmDqN3C hVOfmFeU+AfHEf7ff7c8v7QXxklt/C/g/wAKxrquqSWkIWLT9NtG3Q24xjc7HCL6lvesfx3b/sOf ADRLiDwR8RNc+KviCO2mj0D7RZm30fTmlRitxh+ZGRtuY8AFiCeles/8E6P+COnx/wD2o/CkPi7x /wCILjwf8O9ZaG8YKf8ASdVjUkAKvZcZwW4zzjoa9uUsFhMNVxVabjzaRbVrLtFeh87Sjj8djKOF owUuVpytrqurfqfVP7PnjnwH/wAFoNa+IFpr3wi/sHT/AA3HAnhnxhboRO7MzARyZ4JCgMV7bsVx H/BUDwd4Q/4Jt/sAxfs4+ANckufEfxS1gx63qjR7ZLmyt1VpgCPujc0C7ehV5PU1+lv7P/7O/wAL v2Z/hvY/C34ReGINL0uxQBRDGN8zYwXc9Wc9ye9fEf8AwWX/AOCYX7Sf7cfxX8JeOvgrrenSWOl6 DJp15pmp3hhEE3nNIJl4IO4MFPp5a9c1+aZbTyN8TLGcqhFO931suvqz9vzbPuNFwLLJlXlOMre6 norvp6I8s/Zv8J63/wAE5v8Agij4m/ao0CwWPxt8QrG2vILpmG62t7uVLaxYHuFjmFxjuZSvasH/ AIJU/ssfs9fCf9ni8/4KQ/tpa3Z3HnST3GjrrEwlVERiPO2nJeV5AwCnJ496+/8Ax7+wnpXxZ/4J 76V+xD4/17mx8F6XpMmrafFtUXVlFCEnRT0XzIg209uK+KfDH/BvB8YdQtdL8BfFL9riW88F6bdG b+xdPtZV68nYGYqpJzzjvxX0VDNsHiKNZ1avJKU7tpauPRJnwFbI8ww1agqdHnhGGi6KT3bR8Pz/ ALWHxN8GfH74jftrfBTwr/Ydj4tuNQ0fSryOPYtn5+xv3Y/viNA2O2+vpD9ir4ZfszfsjfsuXn7f 37Yb2PiXxj4kje48H+Gr6ZZppVckRuYyTlpD85c8LGfXg/f37RP/AASX+AXxb/ZHtf2W/AWnw+Go dJmFzoupQwBpEuQuGkk7vv8A4u5GK8L/AGTv+DfTwN8MPGNj40/aO+J8njj+x5mfS9DSF0sh93aX V2JIBB+UYU8ccV3T4hyjE4Fq7g7pOy96UVsr9PM8+HC+eYTGaJTTTau/di3vp+R8GfsS6jo/7RX7 ZnjX9rP44abbSad4F8O6l481XR7KzCwzLaBFit0QcYV3iOP4lTB6mu3/AGJ/C3w0/bL+KvxE/bu/ bz+IlovhvwnPHNeaXdTHE8koYxQxrnOxQm0Ko5Yj1r7Y/ZV/4Iead+zx8Ufidd6p8S4dS8F+PPB+ qeHLXRobd1ubS1uriN1LSE4YrHHtzjJJzXn/AMIf+DcPw74X8b3UvxT+Pd3qnhNbpZotHsYDA1yq twJyTtzj+6OKuvxBldeVS1Rx0iou12o21S8+lyMPwznVGME6afvNvom+jfkfIGmXGkf8FRv+Chmj +GfD3h3T/DPgXSVYx29rClv9i0W2O53fpl24BPbf7Vu3MHhr/gpn/wAFPJvD/iDxbBb/AAv8HpNI bq5vPLht/D9gyKdu8/KZmMatzkeazDpX0x8ef+CWH7Hvw1/aEvPiKn7YFj8PvD2qwta6h4dsbxIp 1jwu+3RgciNlXkEZzzXz38R/+Ce/7Llp4F8dftY/Bz9qi/tfhfosdxaX2lSaXLBqF3O0avFYRPJh ZN8hg5IIwcnoa3o5xk+KrxhSqNe5yx0u03u/NnNiMizvBUHUq001zXlrZNLb5HP/APBU79vOb9sT 4l6X+zJ+znbbfh74avI9P8PWenQsq6vcALGsoQDlF5WMY5HzdTX6/wD/AATo/ZStv2Pv2VPDnwlu LaMat9lW+8QSR4w99KAZACOoTAQHuEB71+UX/BDT9knQfF/xNuv2zvjK8Nj4I+Hcm7T7y/bZFPqY 5QjPVYgdxPZ9g9a/dSA7oUdf4gDx9K8HizFYXDxhluFd4w1k+rk+/ofU8FYHFYmc80xa96WkV0UV 2JdjelPoor4k/QwooooAKKKKAAnHWoZLlVX5vxp5Yngivhz/AILo/t23P7H37J03gnwFrHk+NviF 5ul6O0b4ksbXYDdXXqCEIjU8HfKGB+Q0AfGf/BVP9r/x3/wUt/ags/2Cf2Vta87wlpF0Trl9GSIL 66hbMkxdc5t4wNq9mfJ7rX1x+zz+z78Pf2a/hZp/wq+HGntb2NmpM0rnMlzKesjt3JP5DpXzn/wS A/ZJtvgf8Cbf4xeKdMaPxR42s0uj9oX95Z2B5gh56bwBKe/Kg/dr7F+bPWvic8zR1a3sofCt7dWf qnDOTRw2GVaqlzS/BGhba3rMChI9VnXaPlAlOAKR5pp5PMlkZmzkszHr+NVFYn5hUscvHzGvnnXq z0u38z6RYPDwk5Rgl8i1uycD6fpViHavH4VTSfJwKmRsjKvWRNSj5F6Ibh94VMgCfdqnDKOmasB9 p5NZ3fU45UlHYzfHPgfwz8R/CV54I8Y6RHfabfR+XcW8ncdiCOhB5BHINcD4L/aX+Mv7EPiGz8Bf FnR9W8cfDK6k26Z4stVM194fjHPlXa9ZY17SDnbwfWvUllPVTRPDb3MD2tzCkkcilZI5FBVgRjBH oRXqZfmlbL5XWqfT9Txcyymhj466Poz0nS/2qvgh4n+Eer/GjwN47sda0fRdHuNRvH0+4DSJDFG0 j5Tqp2qeor8dPAvjOT/gq1+0z4s+Ln7VXxwHhX4X+F5I7gaPJqHlqYS0nkW8ak/MdsblmwT17mv0 I8EfswfBHwH8Vbz4paD4XNo2raTdadr2k2spWz1C3nRUbfF93ICkDj+I+teI69/wQ6/Yv1TxrN4l 0r4keJtO0C6maS48L2soCliWwA/UBS2evTjvX61wrxNkNOjVdefLNpJO23e1/wAz8X4w4V4grVac cPHmgm21tftc+Rvhv8BvCX/BRz9t/SfhR+zZ8Pf7D+EvhOaKCbUEtyHeyhC+bcyues8xUBQT/d9z X7v+EfC2i+DfDdj4W8NadHaWOnWkdtZ28K4WOJFCqo9sCvgH4L/tIad+wP4Vu/hl8NP+CcXi630H SdQljvNc03Vba4kvhu/4+Pu75c8+n0r0rW/+C0PwJ8OeHY/E2r/Af4sR2rKrTTDwc22LI5z846fS ujOuIKObSjCjP3IKyu7v1fmzn4f4XrZLTnOrG9Sbu7KyXZI+yx/dNNIC87q+OtE/4LlfsJarpy3s +u+JLFn5+z3nhudZF/AA/wA6x9a/4L5fsX2Wvx+HNB8LfEDXJpJNkbaT4TkdWP8AwIrXi+0hvdH0 nsa38rPt4Aj5iaHbsDXxb8RP+Czfhbw2bOx8B/sk/FLxBfXjKI7WTRfsark/xO24CsDxB/wUS/4K E+OfFLaL8HP2HbHQ7D+x2nk1Dxpro4uDjCJ5PBxnoV59axli8NT+Ka+80jhMVN2UH9x93mTHU981 yfxN+Ofwf+Dnh668SfEz4jaTo1nZxyPNJeXqIV2IXIxnJO1WbHXAr4V1Hwn/AMFRvjjY+V8W/wBq zSvB9pd6NJDcad4K0kLIszNn5pH4OF4DAA1b8Lf8E5fgRY6pca/8SLzWvG+oXU7zSXHirVJLpQXg ELLsY7cbd2P96vPxGe4CirqXN6HpYfIMwrWurep3fxJ/4K9eHNa12TwR+yH8Fde+JGqrdJbtqUcJ tdNibz442JnccgK5bI/u4NcRD8Nv2+P2oUn1r9pv9ouPwD4dhtZbrUNA8ELtaC3EW5/MnPJIyVIH HGRXtui+HPD3hWxXTvDuiWtjCudsVtCqDPrwPp9a1bHVIdLEy3lrHPa3Vu0F5bTH5ZYmUgqfbB/G vFXEftMTG65YX172PYlwz7PCylF3nZ27XPi74c/Ef/gif4c0/UvHMPj1tZuNPuGjvJvE8Ml1dXgc qSY/MJ3j0PpXgPxY+J3xv/4LE/HTTfgf8HvCq+D/AIR6HetItyLcJBbwJ8jXty4wryGMYVO24D1N e1ftC/sc/wDBIj4Ia7efGv4gaVqljaWcHmyeGbXVcWs+SeETqxJ4AHevM/h54t+Of/BSv4hWn7Mf 7C3gCb4U/A2x/ca5rFlb+XPcRb/3kry4+dyDhY84BOT3r9Sy3M+HsLF18DFyqNby2i+6PyzMcn4k xklh8xcY0k9o7yXZ9kezXfhe8/aA8OaX/wAEuv2B7LHw78HSWtr8QPiU6/6O0scyvOikcTzyuG3g cYdh6V+qNpEIbeOM/wAKAfpXm37LX7L/AMLv2Rvg1pfwY+Emk/Z9O06M+ZNM2+a7mZt0k8rdWdmJ Yk9z7V6auMZIrwqkp1Kkpzd23dvue/TjTpUY0qceWMVZIfRQDnmikUFFFFABRRQc44oAjD5PWvwN /ay8XTf8FSP+Cxn/AAgonGoeB/DGpHTVjKCW3OlaeS9wcoQdlzMGUMclTcqOQMV+xX7f/wAdpv2b P2NPiJ8ZbKeaK80nw3Oumy2+N8d1N+4ikXdwSskitj0WvyJ/4ISfDE6zf/ED9oTVrO2muGmh0Wyv Fc+dHIwF1dLtHADA2jeuU4468eYVvquDnPray9T1Mlwn13MqcHtdXP0ZjiigjWO3hVFVcIirgADp +H8hUxfPINM3bR8zd8VyPxP+N/w4+EWiya9458TWljDGpJ86dV3fT1r8z/eVJO27Z+3fucPTS7HZ RyYHWlNzgYIFfBHxn/4LafC3w69xpnwu8P3WtTLGxjmChITIGwFJPOCvzZArwXxZ/wAFo/jtfeKV v/DngzSbXS0t1C2t9JJLIJCBuO8EcH0x+NehRyPNK8eZRsvuPGxHEeT4eVp1Ney1P10ivo2G1m5q dL0bPl/vYr8dNY/4LJ/tIXVv5ek+FvD0Em7JcrMw2/8Afdem/DT/AILWWMd6lp458A3mmwt5AN1p 155o3/8ALVmU9FHYZPp70VshzWlHmcL+hlR4jyXEy5fa29UfqPHdEDJNTea+N5avmn4E/t7fCT4z 2ynwp4xtLyXaHe1kcRXCnGcbT16qOPXmvctF8d6Hqq/uLtVb+KOT5TmvHlzU5NTXK10Z66pKpDnp NSXdanURTt/CamRyRktWbBdIy7lfdnnrU0d0C21jU8xzyp+RcEhJ+YU5DkdBVXz16bqekjKOKoyl R8ixkOmw7drdeKbLDZXVt9ku7SOSNlwUkjBUj6GolmZzgNR9oVTgHr61Uako7Mxlhqct0VT4M8FF vMbwppv/AAKxj/wp8HhLwjaSLcWvhjT45F5WRLNAR+Q61P55xnNNe6RV+eVQKv21S2rf4i+qw/l/ BFp2hl2l4gzD7ue1O8xT8pxWLd+KtGsNwutSiVlXONw6etct4u/aD+Hng6xl1LVdZihjihMjPNMI 12jqfmPao5pStqaRw3LrY9D+0KExiq8+p2lovmz3Mca+rmvjn4z/APBXX4A/D/7Vp+n+LY768h8x Db6bGZmMiruC7vujdnAPIr5B+Nv/AAWA+OPxQvZPD3wL8Ltp0klx+4urmM3Vy6iVGUiMDaMgOrAh shxjGK9DC5Rj8U/cg7Pq9jgxOY5Xgo/vaib7LVn6ifEz9qD4U/DHS31XxP4ntbaNVZlkuLhY1YAB uCepwewPSvg/9pn/AILWNrEs3g/9nvw7Nq16zbYdQkjIt1b5fux43SnlsZ4zxgg15n8Af+CUH/BR H9uXVrbxH8S31LRdHZ9kmqeLJHDLGplUlIjyTlNnQfeU9Dmv1V/Yg/4Iz/sm/sbRW/iVfD58VeLB HibXtcjWTy2IXIij+6g3AkHBbnGa+owfDNCj72IlzO+y2Pk8dxTUn7uEjy+b1fyPz5/Y+/4I7ftY ft7+L4/jH+254r1jQ/DImi22d5lby/h+8Y4l6QIc7d2MgZwAcEfsv8GPgb8LvgD4Fsvh18I/B9no mkWNusVvbWsIXKgAZPqSByT3rrIoY4kWONAoA+VcdB2qwqKUAIr6SMadOPLBJLsj5SrWq1qjnUld vqJ5K0/AAxRRVGQUUUUAFFFFABQelFBGRg0Afmz/AMHMHxUs/Cn7Gfhv4YJd3EN54r8YRvD9ncqs sNrGWkR/VT5qceoFeW/8EbtN8DaH+w/peq6HJbfbtQ1i+n8RbJPmW4WZok3js3kJFx6YrY/4Omli b4T/AAhl/iTxFqgDembeD/Cvzn/Yjm/bA+Mtpqn7FH7LdxcqvjjU4bnWLqEuBYQKuyZzIOIY3BjD t1YRqgPzsDy5lg6mNwfs13PYyHMKeWYz2tTXf8T7s/bD/wCCpXg74YTWvgD4E2P/AAl3ii4uhG1v p+6SOH/ZymS7E8BV+ucDngfgn/wRo/by/bo1tfib+1t43uvCekXU0ki2dy2+5RS4O1Is7YxzxnP3 cV+g/wDwTp/4I+/AT9hXSZPE2oWkfivx1qEajUPEmqW4byQDnyrdTnylJwSfvNhcnCqB9erHsXCo PQccCubAZXhcBG8Vdvq9zbNM+xmY1Gua0eiR8P8AwV/4IDf8E/8A4WaSsHin4f3Piy9LRSSXmt3b HEiDqqqQFBPJWvoGL9gj9jWG2jtB+zV4PKKoVd2ixHgevFeyFFPVaCg7V6vMzwfU+e/iP/wTA/YR +KejR6H4s/Zq8N/Z45lkUWVkLdgy9OY8HHtXyl+0h/wbZfszePba81j4DeLdU8H6nJNJNDbvJ9ot AxXCoFblFDc8HNfpjsX0pGUY4FHNID+bv9o3/gkJ+3h+yBqB8Taf4Qu9YsbPdNHrfhZmcxqnO5lX 5xgAN35rD+Cv/BTL9o74M3B8LePov+EgtrNTb/ZdXVkubdlMS4L8NlESQbW6mQk9K/pXubNbmJre 5gWRG4ZWXII/H1rw79of/gm1+xr+1BZzRfFn4D6Nc3kkMka6tZ24t7yHzHDOUmjwysSBlgc1zYrB 4PGRtVgn59fvPQwWaY7L5c1GbX5fcfmF8Lv+Cw3wS1dLeHxFc6t4fmkjmaUTp50USxs3lLkclmXa cAdTg9M17Xof/BSn4Bajo1v4hl+MGhrb3yq1vDcSGN4/Zh1B+tafxc/4Nkf2ZPEVzqmp/CP4qeJP Dr3LR/2bp926XdtZhYwpALDzXDMC3zOcZwOABXhHxM/4Nf8A456baWf/AAqr9oDQ9WmLYvP7ZsZL dUHqmwtnPoeleBW4TwMpc1Kbj5bn1FHjrHRjatTjJ97WPqTwj+1x8OfFNrHe6T4w0S6ib7rxapGv 6Mwrcl/aS8HW6eY2saX/AODeD/4qviNv+Dar9s/Trcmw+M/hdm7RxzTjn8RVX/iHJ/b0uJSkvxM8 OqueGN/N/hXP/qfHpW/A6v8AXin1w6+8+sPFX/BQb4D+FL5tK1f4k6Fa3AbDJJfhsf8AfIIrkfiB /wAFSP2efAmnW8178S9Nkkun2o2m7p9vuwHT614De/8ABs3+2TdWpnT4teD2uODtmec556Z2113w /wD+DX34tal4baT4l/tG6XpmqCTEcOl6Y9xEF/3mZefwxWkOEaH26rfoY1OOKj+CjFepe8bf8Fl/ gfoeuW+iWmvalfQmPfJf6dYgIOM4O4g14v4+/wCC3GqXVncN4P8AhvO1018VLahfnypbbOFO1cEF hnjPFfWXgz/g2B+A0OiQr4++Pnii61BZleWbTIYIY2UEZXa6OefXOfTBr6B+G/8AwQd/4Jw/DnU5 tUHwPGuG5tRBcW/iLUJb2AjuyxSMVQn1AFdlHhnLafx3l6s4K3GWbVPgtH0R+Oniz/gpV+2J8YdS vtM+Gls9iv2z7Zb2ugaY09xbW42gREgMzJnqT1z9K1Ph7/wTk/4Kf/tZais+qeB/EkVo1x8194kv GhjRZvmYhWOSvHOBx0xX9Avw8/Zs+Bnwn0+30z4cfCLQNHhtLVbe3FjpkaFYkACpkD7uAK7eC1SB AqQKu0YwqivVoYHA4X+HTSPExObZji/4tVv8j8f/ANnD/g2Sup7mz179p34wMqARyXWi+H48bjgh kMzc/wB0grg8V+g37OP/AATW/Y8/ZdsoY/hf8GNLS8TBbVr+AT3MkgjVC5d84LKozjGTzX0FgDjF IVBGK6+botjzdb3ZBBBHFEEigVR/dVRj3/xqTZkYC1IBjgUVICBQO1LRRQAUUUUAFFFFABRRRQAU E4GaKKAPh3/gtt/wT1+KX7e3wa8JaX8HL21Gu+F9eluI7S9m8uKaGaMK7FsHDKUTGB/EfSvSP+Cb P/BOj4WfsCfB6HQtD0W1uPF2rW8Mvi7xFs3TXU6pjy1Y8rEhLbUHA3MerEn6WaI460JEeuarm92w eY/Dbs0nz4p1FSAUUUUAFFFFABRRRQADOOaPaiigBvl+9G1v71OooAKQqDzS0UAFFFFABRRRQAUU UUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRR QAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFA BRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAF FFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQAUUUUAFFFFABRRRQB// 2R==

Clinical and paraclinical manifestations of hospitalized patients with COVID-19 in a selected teaching and medical center of Qazvin University of Medical Sciences: A cross-sectional study

Leili

Yekefallah

iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAGXRFWHRTb2Z0d2FyZQBBZG9iZSBJ bWFnZVJlYWR5ccllPAAAAyZpVFh0WE1MOmNvbS5hZG9iZS54bXAAAAAAADw/eHBhY2tldCBiZWdp bj0i77u/IiBpZD0iVzVNME1wQ2VoaUh6cmVTek5UY3prYzlkIj8+IDx4OnhtcG1ldGEgeG1sbnM6 eD0iYWRvYmU6bnM6bWV0YS8iIHg6eG1wdGs9IkFkb2JlIFhNUCBDb3JlIDUuNi1jMTM4IDc5LjE1 OTgyNCwgMjAxNi8wOS8xNC0wMTowOTowMSAgICAgICAgIj4gPHJkZjpSREYgeG1sbnM6cmRmPSJo dHRwOi8vd3d3LnczLm9yZy8xOTk5LzAyLzIyLXJkZi1zeW50YXgtbnMjIj4gPHJkZjpEZXNjcmlw dGlvbiByZGY6YWJvdXQ9IiIgeG1sbnM6eG1wPSJodHRwOi8vbnMuYWRvYmUuY29tL3hhcC8xLjAv IiB4bWxuczp4bXBNTT0iaHR0cDovL25zLmFkb2JlLmNvbS94YXAvMS4wL21tLyIgeG1sbnM6c3RS ZWY9Imh0dHA6Ly9ucy5hZG9iZS5jb20veGFwLzEuMC9zVHlwZS9SZXNvdXJjZVJlZiMiIHhtcDpD cmVhdG9yVG9vbD0iQWRvYmUgUGhvdG9zaG9wIENDIDIwMTcgKFdpbmRvd3MpIiB4bXBNTTpJbnN0 YW5jZUlEPSJ4bXAuaWlkOjlBNTZDQTk3MUYwRDExRThCRTZCQjBDQkNBRjY3MTg5IiB4bXBNTTpE b2N1bWVudElEPSJ4bXAuZGlkOjlBNTZDQTk4MUYwRDExRThCRTZCQjBDQkNBRjY3MTg5Ij4gPHht cE1NOkRlcml2ZWRGcm9tIHN0UmVmOmluc3RhbmNlSUQ9InhtcC5paWQ6OUE1NkNBOTUxRjBEMTFF OEJFNkJCMENCQ0FGNjcxODkiIHN0UmVmOmRvY3VtZW50SUQ9InhtcC5kaWQ6OUE1NkNBOTYxRjBE MTFFOEJFNkJCMENCQ0FGNjcxODkiLz4gPC9yZGY6RGVzY3JpcHRpb24+IDwvcmRmOlJERj4gPC94 OnhtcG1ldGE+IDw/eHBhY2tldCBlbmQ9InIiPz5MKu88AAABHUlEQVR42mJkQAPLzlkmAKl4IHZA kzoAxAujjI4vQBZkRNKoAKTWA7EBA35wAYgDgQY9AHGYkDSfB2mONDzGoCuZzPDm0wdcBoAsOA/V AzEAarMAA/FAAKqHgRHq5/kwGWSbRfgQZrIx8zD8+vsF3aBEFmiAwUGu/TWGKy/mMuy/2csA8g4y ePLxEMPJhy3IBsUzYQltFDD5oBbD8vNWDHtv5zAIcqoyGMkUIEs7MBHr6VdfzjGceNjKoCjkhSLO RELAgQ1BByQZIMZjhNWAA8RqtpCvZrj/bhtK6gTFwkJ8AQmKFeRYOPdkArL0QkZoSjxPRBLGSNLA 5GwIC4NAIP5AguYPUD2QQIRmDENoRmEgIjMZwjITI6XZGSDAACGSYL54CbRMAAAAAElFTkSuQmCC

; Mahnaz Moradi

; Sareh Mohammadi*

iVBORw0KGgoAAAANSUhEUgAAABkAAAAZCAYAAAGz7rX1AAAAAXNSR0IArs4c6QAAAARnQU1BAACx jwv8YQUAAAAJcEhZcwAAFxEAABcRAcom8z8AAAWXSURBVDhPjVXrb1NlGG+Mf4NfjCERokyoTui2 026AIgIywIjRD2KiBi8fTNQPzk8maqLOBDGOyYiKg97XtesUnVFQLhuwtT2n57Rl0JVNOroV2IBt bAMGjp/P8/RCB1F5kic9fd/nfvm9JiaXqnS4NGuH/HFrtl/UTCOmZrLgbzlIjvgQzmzNHTCxeFGF yRO1Qj72RBaT7lkSrYBpd7gMyfMd+C35au62KMbUmlyEwbH9aNFt8EQV/NS/7JbU7vAjOHHeDWPI DYf6OP02kVBee+/AcjlkIea9A3lNJntiUVmLYQOzPVFVJocuTflg7GoS2w8/JGa8uhV8Jr76Rtrg VTfh8rUM1Mw2CUYuhsY70R7bgu+7y2AMN8FJPuUiO9GNIF20RFdh4mqaTFG2bM+hPkbqVRKVS1uS 88HEkdwRFdNHMN3j1Svr2uO1M23xtTddapVEmOebxDO+mK2O5UTBpVeUezTrdY9eibbYi3BH1mNH 50IqyGJw9V3aUgp0CaVIZSU5lje1xLjGubIOjXdRaT2U2evQM07sPDIP+/relEQO9r8nBlj+NqVO 6QeXwxhy4bvuhZL1iXNORIcapTSiVAiPK6HTxbH0x2jRasnAYZy7HBbvB/rfES/uQnhMnCAnygnn E//vQpSSM2ypo4EcLZSYv52qUpe/vkXuuOVBb7RG//nk87OeaA2FoBS9tBjWWY+m6Cwjws1hywNu tSrdkXoOTK3RF6gY5aVhwX+8Gm5VSbOsyasrDcFkNdV+GYLGq9jZZcEPoTLpiyNSLkPL4xFM1pCM 0mDy6NaUL25FW/wZXJhKorm7BpmxYzKKkzPDVDEN7YkNYBmWJQ/sVkEwsR5/z16BPfQERif7sP3Q Aoq/GqnRIIZpOrkfLCvjWlC4MTudV0iiqcsML4XiVJfiyvVRCo0nlxRKPZQq7OhaTOeVaDWeKirk PORzCFKcN3FDFC5ODcAZXkub/wrloFJYtGIxSyEHrlIN/LGn8dfFDjgjy5HI2mU8shM9OEnD6TNW UJW4klSlXB+UtD+RG0YOzx4xyzczl7eV7op9YOIucjelqyUNY76j06XEc3NXs1RKgd4n5zlCSzbv Ci9o2BWav88eeTTl1qqmfdSTHMAx6NiEaeynaUVSbt26j+avgcLeHNCs8/Km7iRvwjaf1r3eaZhT wcSa2VMTezBy7Sii2S8Jgtbh26NmqsdSMV5IkVvji9sQOFEt48Ypt8ZtKY+u1LO9vGnau4Mr7uUI uB5UbbgNM9p7azFwoYMgIYNYthkedQMaOx9Gc8hMxi1wMsYQuzRLnisoq0p2IgshM8T1Jbtsn96Y yvc9etV+jjDQW01GKomXwW9sgj/6Ehyh1fjmsBm7jlnxe/ItQo0P0TP4qXBosJ74cxw49S5+PL4R buo+O2U7kjHZZfsmqukIpT4lJaBMmun5aU9sxMhkVNa3/0I7HOGVtJmvYfzKME11Cj2nGxE58zVh m5Og6Yi8eyNTBjn8gnTXk7MKcsbBkl2yL6CYWxFmReaPV4UBkteFQZI3gNGV1yaasaPh0Hw0Eco6 tXIahuWU4RsYvPQnbXiWnG+VVSosbBF5787JFnHCryQvND9UrMc4Y6elUDNfYXrmnLyeDrV8rpPS cnHj/y8T9Uwzth24H9s77yNjZsKsdehJf0bljWHs6gC6059Ihvz4FMtV2ng/NYx7wkDBu87UNxoQ J/7oy7g0PUjIMo6hMcaBEEanE5i8Nkw9OYvTF3/FH6m3BRf8vYzZxIXGzx1hK1qP2+CLVRPArKIo 1xJkrSQF3g0+W00B1NIkPZtjGhBG2EBsjfTGayikn9ufOSNcoNwyKvW8TLxUjFKBXnJIy1baszlM 5wyRPLIs/6/LeDsxLHAEAhMEFwIbBB9czsK2F77vDlZMpn8A+ZkVhWYvT4sAAAAASUVORK5CYIJ=

1.Associate Professor of Nursing, Department of Nursing, Social Determinants of Health Research Center, School of Nursing & Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.

Master of Intensive Care Nursing, Alborz University of Medical Sciences, Karaj, Iran.

Master student of Nursing Intensive Care, Student Research Committee, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran.

sareh.m62@gmail.com

Article Info

Abstract

Article type:

Research/ Orginal

Article history:

Received 11 December 2024

Received in revised form 9 April 2025

Accepted

May 2025

Available online 1 July 2025

Keywords

Covid-19,

Laboratory

manifestations,

clinical

manifestations

Objective:

The Covid-19 disease is considered the most significant and most severe pandemic after the 1918 flu, the emergence of this disease created unprecedented challenges for public health. The present study was conducted with the aim of determi

ning the clinical and paraclinical characteristics of hospitalized patients suffering from covid-19 in the selected medical training center of Bu Ali Sina, Qazvin.

Method:

In this cross-sectional comparative description, a total of 324 hospitalized patients with COVID-19 (149 women and 175 men) were selected and included in the study using a random sampling method. The data collection method was a case study and recording of clinical and laboratory findings. After collection, the data were analyzed using independent t-tests and multivariate regression.

Results:

Deceased patients were older (P≤

0.001) and had more underlying diseases (P≤ 0.001) than survivors. There was a significant difference in clinical symptoms of fever after hospitalization (P=

0.015), chills (P=

0.004), dry cough (P≤

0.001), and cardiac symptoms (P=

0.018) between the deceased and survivor groups. Increased levels of CRP (P= 0.001), erythrocyte sedimentation rate (P=0.020), and lactate dehydrogenase (P= 0.009), and decreased mean sodium (P= 0.001) showed a significant difference in the deceased patients compared to the survivor group.

Conclusions:

Respiratory symptoms, dry cough, headache, chills, radiological findings of consolidation, laboratory symptoms of lymphocyte reduction, as well as among the demographic factors of old age and having underlying diseases were common manifestations in this research.

Cite this article

Yekefallah

Moradi

Mohammadi

16-30

http

//doi.org/

10.22087/ca.to.2025.409245.101

iVBORw0KGgoAAAANSUhEUgAAAIcAAAAyCAYAAAB24MjMAAAAAXNSR0IArs4c6QAAAARnQU1BAACx jwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAA9ASURBVHhe7Z0JXI35GsefCtmFVNbs+56tXMuI uFnKWEbWmcG4Pvax3aGhYbjWoWxh5uqO7gfZtywZY20sWUYUQ6VkFCpUSOGe33Pef73neE+JTO+5 znc+53PerfL+3+f/7P93zF5rIBMmFDCXvk2YeAOzyMjI11OmTKETJ07Q87Tn0mETHyuFLQtT+/bt acmSJWTm5ub2Ov1VOnXq0onMzE2K5GPn9atXdDToKBU0L0hmZa3Lvp7mOZ2qVa8mnTbxsRMVGUWL vl9I5mlpaWRu0hh5wsuXLykpMYliomMo7s84evr0qXTGuIA8QC7Mipco/nr2PC+yr2ovnco9GJTH jx7TwwcPKSUlhVKSkyn5SQplvMyg4sWLU4kSJahosaJUpmwZKl2mNBUpUkT6SePmZcZLuhNzh8Kv hdOF8yF0LfQaj4WcEiVLUBunNtSoSSOqU68u37/aib4dTd/N9Ho/4XilsU+XQi7S/j2BFB8XpxGI ZJY4pei4QIECpPlb2sFybEMu3btSqVKlpLPGx9PUp+T34wYKORvCEyInzMzMyNbWltz79aYOzh3I wtxCOqM+3ks4IACXL16mnQE7KDIiUjqaOywLW5JrD1dy7tqZytmU48EzFq5euco2+flzbXRXpUoV atGiBbVq1Ypq165NlSpVYpMSHR1NoaGhdO7cOQoJCck0M601mmT4qOFkVdqK99XGOwtHSnIKrVq+ kq5cvkLp6enSUS14wPb29mRjY0N2dnZsTu7evUsPHjzggVKaYdblrGnQsMHUtn1b6Yi6CT4VTOtX r6dUzb3APE6YMIHGjBlDFSpUMOi7paam0p07d2jkyJF0+vRpPob7xrjb2NrwvprItXDAVERH3aaf 1v5EN8JvSEc1cXHhwtShQweOjfv27cszRwnMst27d9PRo0fp8OHDdPv2bemM1gHqO6AvdXfroWp/ JOxqGH0/ay5lZGRQ+fLlydfXl3r16iWd1RIWFkZ79+4lKysrGjx4MBUrVkw6ozFFGs3h6elJa9eu 5e16DeoRIkX5NWpACIdFIctCXh2dO/LNZEdURBQt1KjS2JhY6QhRgwYNaMeOHTx7OnXqRGXLlpXO vAl8joYNG1L37t1pwIABVKhQIbp48SJrHwgenDr4LA6tHKSfUB+eU2fyQ4VgnDx5khwdHaUzWiA0 bdu2pa1bt9K+ffv4nj/55BPpLFHBggXJxcWFSpYsyRPkwf0HFHsnlpzatVWVWUVwcfzosbdLn/95 909avngZJSYk8j5uEiry+PHj1KZNm1zNdmgJDO68efNoy5YtVKtWLT4O5/bIoSD673/86cWLF3xM TazxWU1JSUm8vWrVKqpRowZvy3n8WBOxPXwo7RFfr++cQwhGjx5NX3zxBe/Dof390u+8rTZyFA74 GL4+ayjuXhzvY8Z7e3vTypUrs9UUOYFB6tGjBx05coQFTLBv9z46G3xW2lMH18PC6cSvJ3h7/Pjx 5O7uztv6YDzmzJnD4Tuc0smTJytqBGgUCBj8MxB08DBlpGfwtprIVjgg9Tu27qDr4dd5H7MegzNi xAgWkrwAnv7GjRupZs2avI/cAULEhIcJvK8Gwq9d5/wFHvj8+fMVH3hsbCxrwnLlytG6deto0aJF FBwcTHv27HnDcQcYP/gfFhYWFBYaxlpHbWQrHEjqHNgbKO0RDR06lAcHZiUvgWBgEK2trXkfvof3 Em/FfEl+cC30Kn/37t2bihYtytv6wDEdNGgQDRkyROfTr18/OnDggHSVLq1bt2Ytg2jmbuxd6ah6 MCgcL9LSaNe2nZkZv2rVqtHs2bPzXDAEderUoXHjxkl7RJERERwdqAFMElCxYkVFrQESExN5rPQ/ 8J8ePXokXaULHHr4X+Dcb+oypcCgcMTFxdOtm7ekPaLhw4dn2sgPAUwWoh5hrl6kveBEmxoQGqxx 48b8nVdA0IS2fNdk4ofEoHBcvnCJU8QAnvn06dPfmDUI3U6dOkXLly9nG7tixQrOCGLGyEEkcuXK FXZicR2uRyiob4uRTof/ITjx63FpK38RwlG1alX+zktEjgMhrdowKBzIBAoGDhzIHrYcZDsRbXTu 3JkmTZrEwgNnFXYUzUMQCAABQNiGiATncR2u79KlC9tpfQFBnkAMGCqcanDUxKRITk7m77wEEwyg MKk2FIUjNSWVIm9p1RxyGBAAOch2wtk6dOgQ11ngpDk4OHBh6dmzZ6wZkAeBvZ06dSr9/PPPfBwm A6oZEQp+7uDBg9SxY0cdm1ymTBlycnKS9ogCZQ5xviEpzBs3sjLD+jRr1ow1rFy74l4wWYTpUOLJ kyf8bf8BtNL7oigcCbJEDjKnqJXI2b59O+3atYu3cQ4mAmFbhMaJRBYUQoIYH6lkHx8fvg5eOdLK KEJhkN3c3DhTOGvWLP4WWFpa6vy9yJv5b4vROgeuXtVGLUoEBATQzJkzdeor7dq1o19++YW6desm HdEFEwYhMKhXvx5/qwlF4XiUlDWToRXwYAXwJ7Zt2ybtEddVmjdvzloB5gC9qFFRUVS/fn3atGmT jjPn7OzMDx/1GH9/fy5Gde3aVWdAMfPkORQMYH6D8gKAsOv7UwJEcfqmV9yL/P7kYFKJrGvT5k35 W00o/quTZMIBsyIXDpiDhISsBFW9eroSX7q0tpkHQgFNIoDKlQ8SfqdcYwgwoHLNkSaVxfOTstba TPD+/ft10uPvC/IfMNEVKlUkaxvDpie/UBQOc/Msu4mHLGa/QP6QDc0kILe/2V2nj+61Wb8jv+jS rQsVKaoV+CZNmhjMW+QGaFhUZ0Gr1i1VV5kFisJhpZn9Aqh1ZPAE0Aro0xDo22FoFnj1EIy6detK R4n++OMPaUsLohThjMnBA5BrpsJFLKWt/KOw5p5XrFvJ2/Hx8ewn6U+Y3ACzi2yrMJlufdx1JpJa UBSO0rIOJdyAvEkHN4E+BQEqs6gloJR99uxZ+vTTT7m+8O2331LPnj2lq7T2eu7cuRya3rx5k5Nq 8Oa/+uorbggSIASWV2XVEuLBBGL5BkA+Z9q0aZmdYLkB+Z4vv/ySM6qYZLO+n03FiqtPawBF4Sgj q7biJuLitBVZQf/+/alPnz68DRU7atQoVovIZQQGBmY+XLTNLV26lAUKwoMZh+gHDUFIdkEQ7t27 x2lpATSKXHNU+YBZ2dwyauw/MvtesOgHfSlyAUFtBZMJ948PHHdRbsC9oocDY3Ts2DEeE5e/u1DD xg35vBpRFA7MVnQpAZgJPHA5uLH169dzVVEeWQBULtesWcOla4DeBZT49ZuJkA1FrQbdYXKgthEW A/g2rj1deVsN4L59/daS498ceRv/dtwXkn5oPcAxCIP4oOKKSQHNii45V1dXFp5SVqXo8xGfU7+B /aXfrE4MtgkeCjxEP/n+yNuVK1dmO4mb1QcZPvgO0CDoZ4CqVArdMHNwHUI3DCjUtNLvw4CLfgks ZfDdoHXa1ITGRSf/Df50YF+gTh8GJooI/TGpoFXgr4lsMYQH13y3YA5Vr1Gdj6mRHNsE4XieOf2b JpRM44eKm9XPlAIIAq5FCIv8BQZACRzHeRHqKgkQtAba6oRZ6u7WnRo0Up/aNdP816RZE2qhiTIg 5HdjY3l8EGVBIDBe0Bi4D+G41qxVk/oO6EdjJ43lbns1k2OboF15O6peM0u64SOEh4dLe3kPZhec WFG/QLKsYeNGvK1WoG0/G/QZrfVbxxquq2s3qmxfWWOWi/EaHQjQyNEjyW+TH81f+i/q3LUzTxBj Idvuc6iXmVNm8AzAzEcaeOfOnfzg8pqgoCDy8PDIdEaxtuPr6V8b1ERqBtrCGP/dAmFWDGoOAIHx GOLBJgA3jIwePHL9Sur7gN+LMj8ETwgGFvtMnDrRaAfYmAVDTrbCATq5OJPT37KqpCieIXR9lxhf CXj5SAgJpw0O2wiNKlZyVk38tUDEX1sUsGAnS4CkjLevT2a/ZPqLdPpmyj8p5nYM7wMs/0Mc/67d YXDgEA6jx0M4bRAI97692Y4DHPdbv4GCDgbxvom/BkRjaPRm4dAe0sWxnRONmTAmM49xP/4+rVjq Qzeua3saoDrRlzFs2DAaO1bjgZd7Ow8cGgLaB4IBP0NEJvg7AwYPoB7uWVnV0ydOk/eS5dKeib8a g8KBJM74yePZMRTgQXov9qaLIRd0imNoZkHGFA3CyHXAYcUHvgp+RsT8SLUvWLCArl/XtvoLsPIe zqc8bEU4haWHcI5M5A8GhQMgoTXu63HU1KGZdITo+bPnvAhns//mNxxTzH4Ih/hAQJD0gqOJD+J/ YUIEEIihw4fqvFkIiaPF8xappvvcEC1btuRloMIBRRgOU4t8DRZX4zg0JCYHgG+FLvvVq1fzWKid bIUD4GUjk7+ZQrXr6C6Qjo+Lp3Wr1lLErYjMRuS3BU0x6JGAf+GscXjlPHv6jNasWE1nTp+RjqiX iRMn0rJly1gYoCGREMMHZX2siUUzNbK9MKPQrlg8fuHCBU70CQdczSAk8NJuKgNNgSUCeJiVq1SW jmqbdfDahCbNmlL5iuV5cHht6CvDsobXDXRw7kg9e/cij8EeVLd+VkkfYJWb9+LldOnCJemIukER DSE4Wh5RS4KQYB+lhh9++IELj2iXDAgIoM2bN7OpRlO2Gle3KZGj5hBoHUYPLlsbKqOjtP8oMYme aNRrwn3tK6CKaYQI76KwsbPhEr1S2hz+BxqafZZ6s0YyFoTmQLM1+mLhc0FToNkYXXB4owD6bWFC cO+LFy+mGTNmvGFa1UqOmkOABxj6eyivm4UWsbWzlc5kAQEqWaoU1w7sq9lTrTq1+Bv7CIuVkkOY Rf4bNtJGv43shBoTQnOgLoXQHp3m4Pz58+x0R0ZGchsljqM1AX0wosHHGHhrzSEHD7l5Cwfq81kf si1vyyZG6cEbAiYIr3PA2pgdAdt5dZsxIjQHlmXgXSNoQ4iJiWGnFEsz4FdAU8JxhxAhdDcmcsyQ KgG1iLfnfefpRXM959CGdf+m4JPB2c58DFDYtTAWhoVzF5LntJm0RRPxGKtgyIFvgc565HwQocnD dOF4iojFmHgnzWEIaA/4FwiBkWUtYFGAUp+m8js+8F4wZFr/n4B28PLKssrobUHIjhWCMCsCLMHA avszZ9QfgcnJU+H42ICvIc8MQzuipVK/7oS3F2HxkjH5G8AkHCYMYv4hX6tgwniBXJj+ZzwmDED0 P7BIB3Al9T5OAAAAAElFTkSuQmCC

Publisher:

Lorestan University of Medical Sciences

This is an open access article under the CC BY 4.0 license

(

https://creativecommons.org/licenses/by/4.0/

)

Exten

Abstract

IntroductionThe outbreak of a new infection, which was eventually identified as coronavirus 2019, has affected all countries around the world. Although COVID-19 is generally an acute and treatable disease, it can also be fatal. The virus is highly infectious and is considered a significant threat to health. Most of the clinical symptoms of this disease were non-specific. Importantly, significant differences in the clinical and demographic characteristics of patients with COVID-19 have been observed in different regions of the world. The results of the studies also show that there is a significant difference between the clinical, laboratory, and epidemiological characteristics of deceased and surviving individuals. The incubation period of COVID-19 infection is estimated to vary between 2 and 14 days, with symptoms appearing on average within 5 to 2 days. The results of various studies show that common symptoms include fever, cough, and muscle aches or fatigue and shortness of breath. In other studies, nausea and vomiting have also been mentioned as symptoms of the disease. In several studies, the association between older age and increased mortality in patients with COVID-19 has been pointed out. Other studies have also reported that the presence of underlying diseases, such as high blood pressure, cardiovascular or cerebrovascular diseases, kidney disease, diabetes, or a history of malignancy and ischemic cerebral diseases, in patients, compared to other patients without underlying diseases, has been associated with increased mortality. So, patients may show normal or low blood cell counts, lymphopenia or thrombocytopenia, and prolonged thromboplastin time and increased C-reactive protein (CRP) may also occur. Meanwhile, increased levels of lactate dehydrogenase (LDH) and increased levels of some liver enzymes, including aspartate transferase (AST) and alanine transferase (ALT), have also been reported. In addition, the likelihood of increased urea and creatinine levels, and D-dimer levels in these patients was very high, and in many patients, the erythrocyte sedimentation rate (ESR) was also high. In terms of radiological symptoms, imaging features in lung CT-scans of patients with COVID-19 can be useful in the initial screening of suspected cases and in assessing the severity and extent of the disease. According to the results of the studies, bilateral lung involvement with a ground-glass pattern was the most common finding in computed tomography images of the chest of these patients. The results of another study also indicated that in the CT-scans of the lungs of most patients with COVID-19, opacities with a ground-glass or mixed pattern were seen. It is evident from ground glass and consolidation. It is also likely that the lesions are more likely to be in the form of peripheral infiltration with bilateral involvement and often in the lower part of the lung and multifocal. While fluid accumulation in the pleural space, lymph node enlargement and lung tissue calcification are rarely reported. Given the widespread prevalence of this disease and its mortality, especially in the elderly, it is necessary for people to pay more attention to preventing the spread of this disease. It is also necessary to take measures in high-risk populations, including children, health workers and the elderly (due to a weaker immune system). Given this issue, the availability of accurate and robust clinical, laboratory and radiological data on the occurrence of this epidemic is necessary and essential to guide public health decision-making. It is also necessary to understand the differences between patient characteristics in different regions to create better clinical awareness and allocate medical resources. Therefore, in order to achieve this goal as much as possible, the research team decided to conduct a descriptive-cross-sectional study with the aim of determining the clinical and paraclinical characteristics of hospitalized patients with COVID-19 at the Bu-Ali Sina Educational and Medical Center in Qazvin, who were hospitalized in this center from the beginning of March 2020 to the beginning of June 2021.

MethodThe present study is a descriptive-cross-sectional and retrospective study and its data included clinical and paraclinical information of patients with COVID-19. All data were collected through patient records. The study population included all patients who were hospitalized in the Specialized Center for Infectious Diseases of Qazvin University of Medical Sciences during a three-month period from the beginning of March 2020 to the beginning of June 2021. Among the study samples, 324 patients (175 women and 149 men) who met the inclusion criteria for the study; those who underwent polymerase chain reaction testing (RT-PCR) and the information required to conduct the research was available in their health records were included in the study. Also, all patients who, according to the researchers' searches in their health records, did not have the necessary information required to achieve the project's goals were excluded from the study. Among these, 8 corona patients with a positive test were transferred to another hospital and were excluded from the study. 38 health records also had incomplete information and history and were excluded from the study. So that, based on the available sampling method, the researchers took samples from survivors and deceased individuals until the desired sample size was reached. Based on the study by Li Liu et al. (2020) on the prevalence of clinical symptoms in patients with COVID-19, the sample size was calculated to be 324 people. After obtaining the code of ethics and necessary permits from Qazvin University of Medical Sciences, the researchers entered the research environment and collected the samples at the stated time. Data were analyzed after collection using SPSS version 23 software.

ResultsIn the present study, the most common symptoms among patients were shortness of breath, weakness and lethargy, and anorexia, respectively. There was a significant difference in clinical symptoms of fever after hospitalization, chills, dry cough, runny nose, abdominal pain, diarrhea, headache, dizziness, and cardiac symptoms between the two groups of deceased and survivors. Ground glass pattern pulmonary lesions were the most common finding in the patients' lung scans.

Conclusion

Respiratory symptoms, dry cough, headache, chills, radiological findings of consolidation,

laboratory signs of decreased lymphocytes, and among demographic factors, advanced age and having underlying diseases were common manifestations in this study, which seems to be more important for health care providers during the evaluation of the patients' well-being.

Funding

This study has no financial support.

Author Contributions

“Designing the research

L.Y, M. M. Data collection: M.M, S.M. Data analysis: L.Y, M.M. Data recording in the software: S.M. Analysis and interpretation of results and writing original draft preparation: L.Y. writing review and editing: M.M, S.M. visualization and supervision: L.Y, M.M. project administration and funding acquisition: M.M, S.M. All authors have read and agreed to the published version of the manuscript.”All authors contributed equally to the conceptualization of the article and writing of the original and subsequent drafts.

Declaration of Generative AI and AI-assisted technologies in the writing processNot used

Conflict of InterestThe authors declare no conflict of interest.

Ethical ConsiderationsThe authors avoided data fabrication, falsification, and plagiarism, and any form of misconduct. The study was approved by the Ethics Committee of Qazvin

University of Medical Sciences (Ethical code: IR.QUMS.REC.1399.125).

Data Availability Statement

Data available on request from the authors.

nowledgementsThe authors would like to thank all participants in the present study.

clinical and paraclinical manifestations of hospitalized patients with covid-19

...

Yekefallah

et.al

Caring Today, Volume 18, Issue 1, 2025 PAGE \* MERGEFORMAT 28 PAGE \* MERGEFORMAT 27

PAGE \* MERGEFORMAT 20

مراقبت امروز،

سا

ل هجدهم

/ شماره

140

Journal homepage: https://caringtoday.lums.ac.ir

شاپا الکترونی

کی

2783-185iVBORw0KGgoAAAANSUhEUgAAAK4AAACQCAYAAAHme2ClAAAAAXNSR0IArs4c6QAAAARnQU1BAACx jwv8YQUAAAAJcEhZcwAAFxEAABcRAcom8z8AAKggSURBVHhe7P0HgBRV9j2O//+7KioqiDnnLOYA CCgZJDOBnDOISDIgOigiOYogURAVyWnIOU9gGAYmD8wMk3Pu3H2+v3NeT7Nj2NXddT+7+/lYeO2e 6qpXr+4779x7X7267//3n7BdNXXq1Hsx+303ZowHFs1y9+7d++rK3/6h7Yqp/h1eQccmQMdGQKdK ad8Qnk4N4eK+Q4fWXVd57G/ertrSucP77g4NgQ4N4O7QGM5O9Sn83rEBP1/j/tfh4UVWd+9+Q+U5 v7pd8VGXjq1dnZrCw0Lc7VhIRQ7g9sBjK4eL/9zJcfytPtD2DTg6vo6QeUG/Wvj/n3KHu10j1qwh HO2awuVywtPhDTj9GrCGDYB29eHQnbjsvGhT/v0GKnhX3tP/+lZtUd/ek+x+9ajDenDanbxAY57M 2+atuzu+ZlTh6vgGPLy4x+4yny5WInbyu10qy/jF7fa0iDBYAxqj4tQpWE0hLJTqsIVth8dtg+30 ITg71GUj1kNph0ZI+XgE3O3rIrdLc2tlGT/b/kSpnf5Of5z97AO4nTbq8Q2MWLkd1rgt8JxeZ3Ra 6t8YbrudCKmDwp4t4XRYkXQqjA36utQhVf5su+qhhx5qcWP/+ajRcxYSPxqJ63p/ggUHomArTcPk eUuR9tUco4rsXh2R69+Md9IMFaXFiD16GDnD+iIoKOiqyrJ+tN0w75tvd1vO7sWtfWdja2wK7BUl 2HDmAhzn1yKxeysUUC1l7RshJOYiouNTsX3/Kdw5eCaOp2Tgu5A49Bs37vrKsi5vV2eF7jvvPLMD 1qj9uLXLh3DF7oEj6SBR5sZV/Wbimr68k37zEJZZCKvVigIH1eF2A04nPlx3kCgpQty5kBcryzPb lR+NGdrWHbYT7oitQFQwPOeo05htlO2wpRwH4AA8/GA5bo/TfArXbrcLzpI0uOK3whm7DWPGDLm1 skwvbj3h24HQ9aZgz1m2/uWCtwDx24C4bXDH8YLxwXDGsRCKO4H747dz/w44Yregdu3HHmNZfzal cruyc6vmbRASDITx5DOUKNY8OtgIVED8Dm8B+ozbDFciL57AivBiNsrUoNFjWc5dlCtMiZXbDdmH t6Q5Qnfi2muvbcG/X6M0uuqqqwIyT2/JNjWN32kKdvG7h7fs4gXyIzblV6tWrSmPVS2rU34Gs1vC Vs3+mp8PUK6lXEmpRrmZ8iRFF3q9UhpSXqaoMOnyGoqw/4ubcCcC+aUDtE+3p2Mkuqh0+FcL+4/Y /lyvXr3rnZu+icSs8R7M/sDjjDiwPSAg4HLr/yNb9YIuLW3oRAvSgfRoLAg5WNbErwkyB/VMrDzu N29q4ZvsbVkIedZBChU/uDvIgshykIs7vkyeqI8ikpT3lN+23WgRoZN/VXDc8AHsYext5Gawp7ld buR0b204WRfM7dq6uPK8v7lV+7BZk96yGDJLrtyLyBw/CG7/N8xFVGN3pzeQt3g2ijZ9R/Ln3bRr iLgpE2pXnv+Lm1Rwt6sTLQcLyFjyGTJ7+/O2X4WTtfMa0ro0T/VZYANkTZmIvMAWVBF/I+N5i/jl 7cqaNWs2eOmteaxFHTjKCmkZaOpp04re7Urb56YaHCgKaAJPW9m/N2j2LCjp0IwGoLEK/qtIuSG5 t1/unZ3fR/o3X6Kc5qhw2wYU9m0DN1nOHUA1sOHstNBlASR5fs9KTsXJQ0d4R01wfuqH4oxf3O5O /WYhKjwuNPhoOQoPHELIpVyUkza3nQpHs1EzWTAblLftphF1UCW5S6dh49mLVBO/nw5PrSznR9uf rrzyyqej0/OQkCcpQVlSCOpN/BoNJ6xGdudmSPVvAjt9iZSPRuHBEVOw+cApPDvuKzz1HmXUl7hx 4AxPZVmXtz/dfPPNd8h6IGI98s4fQkZBEVwxpEynAzf6jccNvb/Etf0X4Bq/j2Al9B4cPhMejwf0 ODBo8UZaDycsORd/ZkxvcofugCdiMxBJko+iRIvkt8GZwH0uC/Frp+mnEaGaPPSEjPXgDjedFhvN l5PGoCDm4GmWdZmgrhrap1tnZzgLqiwY52gpKgtGAi1I3CZy8Q5jQbyWY7v5FEdLPLGbsOP7hVNZ 1o8M6W32cJqhUBI4zZI7kiefp+U4z+8xshjek00BInuaI1kQ/e2WnUsMxh133CED+iOvU9V+2nVy K3JObUvndxF5fcqb86ZM+MJFO6ZaXi6YF3HyLhys/cntX2+55pprXuWxt1HE0z/aROLPvz+0fwA/ a1F8ZK6r30t5iaKL+SxIPcqzlPsoNSg/K9C3qQVlPWSKfrrpN11YJ/ssiP7WXf6o5f+nNl1UXdtU akFQ0HXrKJX7/m2VqrqpElcNGTLk1kubVn3o6d/Gg4GdgYEdKO2BAR0p/D7Aj3+TKAcEmL/dQ3s6 ly1bdv3Jkydl6P/lm7Skpqy5850+Y12Mn2QCJB7RE317F5kbxs8XZZF4FQbRbIDGDR3EkbSa/HRR cjo18Wx6//2bTMm/8+ar6M07RgycaGcw4mGsAGMcveJu34RSD4k9O8Fy4hA86UlAfi67cAzK1i9H Gm9AIZa1Hc9ry4CGMZ67E60yzyvza+Z+/fXXBaXfZVPTX0cn8KGUwCZlHmpKF1NlPTSkZTSotnOn 4PJY4Ei5iKzhPcw+2UUXNWslh5d0bIrM94fBWZQNt9WGLIYcdhoKh4yzDDetkYum7tyw7oP/3//7 f/8U1tVhajR9oXadYvon7k400mx2tG0CV2vGl6lJcDssSAt4k3AQJOjP+DTfjmI+eXMMtozP41fX fKa/1d/YkIK5EyC/yKVy2yuUrI/4IX0jec1/qNLS7A131az57NlvFpbnxcfzYnWotXooCWAEbbMi d/0qE/za/V9i5RSzEpuMYYXl8sA3UEbXxsXWcPg15XGCTl1Wzqt9K72V8vOngKIc729tGQsbjTdA 7OihM3ntv6vSOlju/UPftm+8IsuvGfKO7qbz8Bqsfs0BiwcpHwwjJBqh8N1BKF67CjbC4OKgtrDS btmit8IWfhL5ezfCGR1mwli3vRRZ3VoQr4qVdXN1kB/YHJ9tOoZbA95F7IkTsHdqZm7W4t8Ao+rU +btYRB3glnqPP9y8iB7PgdPRePOjr9F+7kYEztsGe0w8yujDJbw/GtkhRzFy6U64kmhs6S64YjYi /9tPqK3XYWtHV0xOozDaqTE8OdlwXjhv/GsPte3xq08sU7uWCoSmZOMcKw12Sjdxf7F3sx9YB7Xy r27Sru7uoZ79+vW7e+hCzN59CuXRh7H08DnsjErA86MX4bYeU3B1v/kYtnIvIrMK8OTw+SjNuYDP v92Ad+d9izv6BSF94WKDYcHAxUoU8zOXflBYZBSKPhqHtBVzUfvdFbh18BxM3HIcYRvXIXP9d+g2 fxOq9Z2HBQsW/Opwk+7o6lq1at0duv27jY4IehF0XxJSklD3vYUot7tx8+CpKL0QAvv5LSjPiMDA L9bgw40HccegxcjevxfpH49A2qheyJn1EfIO7EFRaQHGfLUN1XtPx+Qth9jZQGftE9zcexJq9p6M Wj0/QWJJGd5btRMPjJgDJ0N+B/0reV133323FPeLWNbOajfffO0d8YeD17lOM749vRGOSMa6kXKN GDxH7UBF0nE4zrHpWVmc20qvZTdcFTmwuRj+05FzuWzItlqQY3PAYS7sgtWl4QGHGSJwO1wYtWI3 +KNcP+/wgceBdFZ41YkY2Kws68IJE0+76WqlXzjxdmXdfrSJuq6/46abHreG73G7Q+iOhtGNOsOK atxCDqLGLuR9apih0lE0XqgqHM99dA5dscGwXTwOT+EleJwVxjOFy8pPjXE44XJY+bXUiMtWBJRn wn5RldvNysmp3Ax3LL3dhGDkRu2KuvHGG+9hveRE/ajCgsD1t91221Plp3bZHSGb4AwnDE5Tg+HB lyusMRHj1f6kwh52Mk88Oxwv6uKFwMqDPqSGNxCr8RHJX/zJquIim7j5m7xh3XRF/F5Po3ovNGd9 7qfI4/uZ5fN1rge3fjl7nj2MFaI/72RFHad3oSTigH3X1/M3rVsye/XmFXPXnt2+8pTz/C64onkB iiqroRF5y0hgq5jK+SrkrawqhPh15ncntehOYFOzghpGKYvd5fjgncEjr7/++jqsw0MU+RQaNP6r zCAoaPjkRVtIsNN1YjNmfPzeKEY3cssfpGhw53bKHRQ1j4ZT5Cg3orT585//HDCkT+fx2ef2X8o5 uznPHr/bkx22Ib3o7NbCgshtRQUx+3NP7Pp+2/BBfUbTM2/LJtZ4UF2KYmIN42hoRiwgH+U30Zcx uxSd/ChFFdNgkZril3qmCtVv0oKaTBrRDenGfip3UhQ6SCG6hsoVHn1DPr9U/m/aVAkV8E8V8sf2 L97UMr6WuqJly5bVlnkHjgWf/5iWUyUMnh988MEaFRV5q7FythNzxrsxczzMo6LZQW7PupVpRUVF bdauXftXLda/cvNV8tqnn376tqJx/TIwkHHbwECAXpo3fpMolmMcpxhOsVzfdiieM2XH8ePHfzZc /6/a1NzVevXyv+vs0N5bjQOv0U2NaOoZTsdmlaOc+ts7zKfhJ9A7Az02d6emKPdrjMTxw/3+1YGn 8Hdts1deeSC9W/MKX+xmRkgZHWj8y/vAiU66Ak5GGOZmKoNNMxDK40A31N3mNcS8PWDjPzsW/Nc2 FXrdo7fd9kBe1zYei7RYWVlFCoqCndwnf1bRgfY56NcqfjPH8NPT6RV+p7+r8KgdP9s2QHyfgO2n g4IUFPxumypavUaNavdn+Ld0uzXASrmsWYbsDj855W8gfeYkempngbx0ICMT1tMnEDOsmxmgtUvL DE6N1qltBZqeNq8j+d3hq1n+b7Jov7apkKtfefTRB84PH5ji9G/Ei0qLlXhUfMbmdoQwdIeNXip9 QrqMHms5pYxupR0uuo5wOJEzfzIr6B2LAKNgwUQxn82vAc7NniJz/09vMpW39HitTlsXm80MjAh3 DFucxF7mOEa3drqFdgvyVi9i8Pkmb8YbKGqou4waz+/SAfnbVsLu8MCRk4aCzk3hroyA7YSKyrK1 a+yJ/WSk/Ih/eFPz39D62WdfyfVv6nL7C6feymq8/dJ7Q+G22RnGJ6I0kIEho189nnCqQ7ECCnf0 uNjNCmvovLBzc7gLs+CxlaCYcLAwmNTjYwWU1m6NENW51Y5/tMOJS+WE3PWtf4spJt5SZ2H062Rl U/p2gNNjQ+nRfWxGDSmpUwnHr5qKGibQjZnO1BBOP+KzU11Y2MEcMYlwssJWDaIwKhaDmGGBtq9j d1CQhkj/7k13WKPRY4/VK+hEjXR8GS6j1foo92fobSmBJzXZXMyjCoqapCVDW6wcO48ZE+Onq5LS 9IzG1bEppRHclkKUHd7rVQArrZvSM4WEgYHred2/u7PJ57xzTECHQRez8pA9shdADapz5G/4mhh1 EI96LCMN1mHH0QCeejorz0oXBtRHiaYotG1CeLBDkjHMDbWvw781FNUEFgfjuaGdzaiQu+OrpiXK 2GqzRo36u4yF7kwm8fHwdwbm3Np3KlK+XmA0WNKVTcZgMOO9t2FhLzYdpE0jap3fO9eH8+BKuIqz ASdZgEGmIz8TaZ+NNBr3tNWwlHiYHcv/deQsWwxXZgrSB7Q1VOjuKFg0xtH+XZ4xtfiNm+z+zQ/e cctr5X6ve1K/mInUAe2IsfrIX7WUlFQBm0iemnJcuoh8di4btew5x6Awej3ceTEoObiDsgsoyyNr ueA6sY+tINrSeXVhZacrCQ1Bre7v4qFOwxHZvY25aVU2tp//bl7/N0NBHevuoyOHrrXxbveePIsT IWdRsX6VCcXzv1kIdzs2I/Faf8JK5M14H86jaxhvbYaT0W9R39bEnzi4Lmxs8qwP3oaLFS7Zzbiv HWHCzuTmjZadDoX1UgLiDhzAvT0+Rb4GBdkCJYQWr/+bWEEsIPP3yAftW4/PGNYP1XrPRrHTjT91 n26mcWQRi+mBTZHy1hDc0HMK3KmnYY3awsiVwWHcNpT5E5/UnIMsIOtWxhtOGdkDVhqHzG6tiF12 tE51UN6+HtLe6g2ny47bu01BQYD6xGuwta2DkFF99UDkVzepX7FW7TMTxmR9fzQKb05dhQNn4/Gn /otgJ69e6h+I91fuwWNDP0f1HlNhSz2JsvzzKL9wGI8PnYL4b77G8wMnEZeiLsKjdRNqsx4cGSko Dz8GBzlXHa44oBVyzp2Gw+HCdX1modD/NRqUOig+e9aze/duBay/6vsKrzfpudGiXcdKbhpArean oCIjBtX7zcDZzHzcO/gLPPnu17ih9zTcwn07Iy9h4LxvURx/CDV6TkbYls14qPdUmlLRF00qoWBh RS6+NwSdJi9H4ZAAFMYm8qZW4apBCxBPtrmt3wJkrZiL7OgEVOv/Bd58f/ZC1uNv4lZ3Isq664EH 7m06aN53sF+ixpLD8eK4r3AwJQs39p0La/YFONNPooi9vePstbiGMCnIiETxJ0OR0L0jSkg/5zu3 JD7prLR9A3mETDE1WnvkfDwyeg5iRr+NG/vNwYkNW3EVKxmTXYyRizbhtm5BaPTJIrz0/iL0n7pq EuvxNysrrdbo2LZlnbKIbR776Z0oi96LJ4dMRmhyFr7cE4ohC9bBGr0F9pjNGLtyIypoia7pOw+H L6Qjb/ZkpI3qicyJw5G9ciHKE2Ow53Q0Hhz2BR7oPwX5NicmbzqGu4dMQ9C2Q3h0yHy0nrgCgZO+ wIVyGz7deARWl5s+RDlSM7M1BvZXO5mp6Ot16z5tPbMfrjPbgDPsNPy0JIZiS2g4Gr+/HPbkU3Cc D4Yjehd7uA0WFr4nLgXVBs7ENf2+wBX957MZv8R1lOo9p6PZh0tRSI/LTjZILizAu98Ew+3xzv3x 0DtzelwoZBk1en8OC7nZTCwqyURpYVpRZZ1+tmnnDU899cgT9sj9cIZrsI40dHYrPKywJ2oHO08I LOf2sJI74Tm/BW5W2J5yhC6ghb3cA7vLwYp7kGNxoJTMIbdQo4wefmqY0+m0It9iwYq9IeZvWg3W V+6jB90+W4UycXHhRdgqn7+WXjjiYJ1+9lhUuLj2ySeffLg0fE+RM2wnELbZO3FJ2j2rkUUN1G2r MompUmIJhwu74MlLMsOaRtyshLRmnnnTr4Wee7PS2qE6Uovyec0/t8OMRFrTTsMZtxPuuE3wJFEh CTux7bvFeqb7s8qqQ922aPLEge7QLUDoVjj0KPs3VNYZvwOe+I1A7HY4E/bCmXkesBZUGQalVA6D uhwWmuky/lQCV3kO3FnnYY2jVYsjNyftAGI28fseuGI3oWtAGz3trkn5EWYNp77wQu0XykP2OFzh rFzoJiDcOyXMjNlS3GZq2M8rizjenMZtNYrI73qE7jIa4s1piJM343vw7334z2PMqCKPrxyB9MSp omxJ7q+I2WZvUPclPSHXAN7Pxmyl1TvCt29Z7Q7fAudpVjSMFw/b8ZsqK2vlNuO1Gtrk8WxGxGi8 lmJuwDck+uNxW01N843Xunmck/uCv/tyTs2aNeXA+Cr6I9rSHxp+fDTzwNZz7lBqJIwXIRRcp1lI BLXASrojd8B1bqcZowU/wc7limEn099mCptXg1Ur4x2n9Wrbleid+eCbkKdzNADt4O/2hGBkRKy/ 8NJztTX17RGKHO+fVVSb8HDTDddc84qTFXWxY6lzOcN3whoRjLh9W87uWPXl2jWLZ6/a8fW8Tfao PQ5HDOmKGtXEHMTwZsy8O0IhYf3linrFexMS/eZKZKslem9KlRY0TgSv2vrkow+1ZB00dquhUrmk 6lC/aGKNZ7V46ifveow2d8AaugOfjH3r/erVqzfhbwK55utpxkUzSvsHH7yvb+yxjbEV0dtcnrjN ZANqUZNSKicLSjTdw0VxS+sUfXfQE7PE7rRdOrUpZurEdz+4+uqr1dPV5JrVoY70i9r0baq9GbJ/ u3e3QfaQTSgO3Wq98cbrVLnHKSpEg8y+QWMNPEsDAn8L+g1+vGDXVQsmL86JCs61JO70aBQ8P2Jz TnHUtsLSuH3lhfFHs8aP7P/hXXfd5T81aKymP+mmNcKu0XSVqUqqDr9I/FU33YXcQMXq9fNObS8k uFUZVVDNoTtVk0jUCVWoRrL1+8MUuW96NtCA4pvnUlW0X7+/QHmKomcIqqBGzdVPVL5g+KtelTYd pGF3XVxD9XpqciPlrxWiv7VfFddNSivqtcKab4i+qqjcWygqUzevm9W50uJfbe6/teniurBv7F8F /ZY79VVcx/s0X1V8LaLfdZwq91vK/dVNBfkK/GP7F2xS7F+TP7Zf2QRxKepy1/D397+mWbNm1VNT U+tt3rz5nkWLFt0VFRX1QmlR9tsVWclBZWnJQRU56eML87ID9u7de+fXX39ds7i4+IVZs2Zdw+9/ 80Hm/+ZNivQpU4oUp1yzf//+J6nMWxPPRfSwzvrstPuDty0Y29+DMf2BMQOAsf34SRld+WmkLzCO 8i6/j+XnmN78uw88H/Sxe2aNy3Zu+eaHi2dDH62i7N+Fp/7TNp9ChUwRs0j/huuuu+7miPfH9L00 IDDG3rWxB/5NgC7NgM7NgcCW/GzBT34P4P7Ojb3S5SeigWT9zrDanNdFwvMCdJ73fEfXN5HXP9Ce MWHEsovH9sm/+F+h6KoKvaZOnTq12rRpeu+m/gE9Evu0SbV10ghOI7j9NCdSM/GopLbeIVV0esM8 x0BH/a3HVPq76nM3DWzrXI211fdKB32vPLZDHfM8zqNrSNEsT+U4WEZ+QFNn2ntD5xzfsuX6nTt3 yvX4r9p8/KkuX/3666+/SdNktvbv8m6cf12P00+P0qg4KaOKmPcTpFA9E2ynAXQqRA98pPD2Gs/T oLsG172jqpoT5338wWP0pKC9ntnU4z4q1uzXMXoFQcPCKlfH6dU8yeso9XsdcYO7rT4RFHTroEGD BID/6M2HVKNUys3rx4xpdWTU8MnF/i2crg714GTXd5nnlD9XrpDq7tQYdj3LpGh6psbK3e1f5b43 UMhzsjs3RWr3Fkjq8SaSu7+JQv/mKCfyrVSq5uvpjUsh3MVzHRpB1qPHdkK1tzzTMHrQwDK95TdC Gc9JHNBlR/bSRW8c+g1T5/4dm89AiU9r3Vajxv31n3ji1YuDOhbbWXmHbtw8k6ICqSTvdOi/iB46 uNq9Zsb6S9s0Ruq4YbBFHIUnNwOwlsLjsJu5sRoO0is8HrvbvE+nN/LMpDOrBZ6CPDgT4lC48itc 7NqMlEG+7eQdkzWPk0QleoRvEK9rUuGmJzSGo11dZAS+4U6cMHbS10FBMoD/EZzsQ6u4S6Pqd9xe q9YTO/p1mldMDtV0bnVtR8dmcBIlUqomEjs1Wq5heyLSQcnu3hqFG76Fu6QQHlcFFWiDS8osykNF 2HFUfDcXmZPHImvUQOQO64XsYd2Q9XZPpI8bgvxpQSjluZak84DNQoW72BB287Sz/NQpZI0ZhGL/ Omw8Cq+l1331yEDP6IRi38NxUY2t02u42DsgceeIEQrdBJh/2ybFCq2KGxVD3tvp5ecbnukdeLqi LRFK8T589HZPL0966cBDJNk6vYrciaPgykuD21ZMZTjhLitA/g9LkDrMHwX+VD4bwaZHckK7UQob R0+yJHoWQ3GaidVEII2XhYoq9nsDWe/0RcmhPfBYrd63lC3FKNi0DoVdWxkjp7eTNRlbfC2K0pMv 89m2CZzt6iG5R4uiMzM+eXnnvBH/FoOnVvW5VTffcsMND7/66KP1M0cOKnfwRs2ja3ZJQwHGKOlR 9huws0vaOrALjqT/WpqPCiLMUeGE/WwCMgZ0gtVfDUAvgGVour2ZG0Iqsev1bTUOjZF34ou6u47V filfQmOmZ53m4a0MYF2D2PQJI+DMzYKVSnaVl6Ng6XwUdWaP0QNdQ1fiYE3b9yLYO42/IYq7NbWH jh/53KGgIA1S/I9tPsXKaKn7PHTNNde8kjgw8CICxGXs9n6vGuNhjIlQ6kcUE4GlgW1QcXArnNYK eNx2lB7bi7xOLYkiGSTvG+R6/O59tM6G4ad5wV6I5Xft9/YAr5LdPNbhJ67+S88wCFQjtKWi9De9 DSvRnT6sM9wFqXC7ee20ZGQM7QJXaz0e1TkCBHmfaNbDa9XB06YpigLa4tz4tzsGBQWph/7Lt6qI NYq988Yb6+4b1CMytn1LZLKClk51eMNEq7ocnXzdtJWVzx7SnZxaAoeFxqmgAOd7+8Pix6DB8B9v huKdyyDEig9506bLywixLM3078Lv/nK3eIyUSXSbGSf8XYo29MPGFArNNAReV42thrGz7CKWkbJo Fo2hHU6bFWlfTEU5f7ez8T3t1bjeumiaDdqzbu3rILdbs+KF3Vrf+K9WcFWO1SDiA2+3btZx2cBe c9Kjo3D3gOloOWExMhbPg03PpY2FrkMaqI/UUX3hKMmFw+OEJfI0MgNa0d16hZz6BrumXo1VVxZ6 xIFSit7dqIcySl63lsjpGWAeyOd+NRtl675BxdbvUfLDUuTOm4qs0TRybEybX11YA4T8+mxc0YlQ rkbTXA0pmFSj953a1kHmu33hzs2G025H0aZvUSEfWg3YvjmPZcOy8Tysk96nAiWpS5uzpz97V4Op /zIj5/MKxEF61v3MtwO6fJbQtaWj4NvF2B5yDiv3nULOlHdhkU9LBMvdyRjK7phDd4rukzMuAsUM T4UMVwA5j0jJCHydimxsECoj5aai7FRKWt+WsO1aAkfsBtgSd8JloaulZ5nkTv1zON3GPbO4LPxu hbMwFwVb1iCNEZkU5GDZ3rfhRCtUFsVNI6o3kKykjOT3RqKsrBSxhcXmHZrMlBSUrV6CClKJ6mIm 2LDBpeBSv4ae+HdHjI6bM0eDyr+7m+ajAznZGvd/PLDuKx12Bby5XQbBxi6cvWg2UhMTUbBhFYp4 c7YuTZDRtQUcaSmAnUqgq5RJxTlJBQ5Vml21bM0y9JmyDMciE1D2fn8GA3WR3LMxLMdXwxW3C47E bXDHboUnJhhxHw4g4ukRUEl2IlMvEKWzMS5NHIuyPTuBCgtcetzpsKJ4/zYivh0RSSXTs0BbKVp2 gPxMD6Ri3CBsPRDK3vY55u4+jfMFLmQXl8NWVo6spBS6eMNhp7djJ7WYqJCfGd1auef5t/zdXTSf LyvnWs+57r/rttteDWjcuEdmh8bWIkZN+aeOo8Gklbi572ScS8nAgfPxaPD+lzgYc4E3TN+zvIge QncTNYkDbeyC5eTnwm0/4P4hUzF2eTCy1i6Bfe8KODWhSM/Y9E6FHiwm7oL7+CoUd2V051ePDcCg hEbQY4yY5pPRYPk3JP00QsbAPvDkpcOjh97FZUj5aATKhFpypzdoED3UZTkNkRPQDMkDApG7fKZ5 id5WVICQs+dxU885OHsyFFld27JscjzLd9JVs5C+DnRpNqF379d/1yHNn6L2iQdvvbVJzLypkUlU bO7GDWj/2feo0WcmDsbnIKnMiSt7zcSfB8zHS2O+goNeQcnG9Sjt2BJZ3VrDEnoKYRdyUVpUguLi UtwQOAMT156AJSMU9sRg2JMo5nHcNpSmHoOdDXN6ThDS/VsgZ+03KFz7PTI6v8mbpcJMEMBuT8Vp zELz5SqI0EL2iAqPhf5zBYrnT6NP3dD4ry6eI8/Fy+uNjCFM6dUODkZ2DrcHe+Mu4eYe0xB//BSK A2RgZTxfJTXUQyF7aFznBpv392nfoPLd1H+aHlSAlKvWUqBw37XXXvviI4880jp819rc5ftP47YB 83BDrynYeCaGCCilN1CCUd8exNWDvsDHmw7BbitHzoVkXIhJxdSNx3FT/9m4YvBCVGNjTNxyGDX7 TMYe/mbNT8aZS5fQc+pqrNt/GCXpoeg/9Rszt2na6mAc2LAJ1/WfiScHT0PKwplmWp15R1azzYhO o2AqUWMMFtJF4uyJDIvtyC8rQd6Gr1HhT2Uy1C32b4ly/zeQ8+FIrDl8Gs+PmYthyzUJx4GlR87h ur4LkLgvGPlUbAW9i3R6OcnsgXWDlqPBB0ucB89dGETP4XcJkX2olU+rl28evfHGG+sHvD3287v7 TPHc238+vjt5FsV5qSiK2YOS+MNIys7GS6NX4JXRXyCfRqf159/hkWFTsOIQuS2jBPEFJXjry00Y t3In+q3YiftHLcTFMgteD/oOtwz9EjEZmbAlH4Tr/F5c2rAcQV+uxdertyBm3Eic2b0RX67ejPxZ n8OpKFAuE1GokTN5HqKGEv9myJgShOSLqWg44Stc3Xcqdh8Pp5/bG+kHduHRPh8g7MABRK7fiPuH sZGVE2noV2zYbHRZuAm135qH3IJ8bD4ahXdWbEeDj5ehRrfPUa3vIvx58AJ0mLjk4OR5y/9p7vUp Vj7tTdWqVXvwpptuevnQpmWrypLDPbbci7DFH4Pj7G5YU85i+/lLuK3PdNw54AvMD2a3crvx9nc7 cd/w+UjJTIclZr+ZomKL3gTLhaNIJsfdP3AKvjkRhfHf7Ua1fvPx2NiFKE5PQtrY/uZ94TJ/8mnH prDTRbPQXSol4gpoFIsCmqK4cwtkD+qEjKAPkPLDD0iJi8HmkGgETv8BN3afhFfHUWH5xfCb9g3m BIci5VIGhi7dgev7T8e4tYeQmJaLKQfOoGav2fCb8jX2xKbgoYHTEZtbjNbTl6LeJ6uQTeSX030s dQMlHg8SC4rLp0yZ8uCIESM0jiI79HejV0oVpwj6N7xSu/bdbzZr9lxyyP7jFed2wHNuO+wRmpNB Q3NmO6xRRGx+NsLjqWxnGWyll7D06HnU7DsXL45ZiMLiQnLoPthitvBzK+wx22FJO4PTyWkosFhg tZYglV3ytsHefFQ3kWbenPA1RnxBxB6IYs+Iw7rj0Vh6OBJjvt4Gv0+W4JWRs3HvkBm4ho35575T UGvAXNzeeyqm7AlHhtVGd81Bn9qDzAo7Mi02jA8+gul7YnAqmb3CY0NwUjqmbDiG4NhL5phSlwsn LqUhyepEy8nf4Y6Bc3GuoJxlMODR/CbNc3LrxQMXCotK1lHBosi/S7k/UirltrovvfR0WsjeY/bw YDhDt3unD2kqEZXqOrsZnsjNcEZS2We3oSKCEncYuyKjDYfay0vpfoXApvkj0buAqN0AG8Z1Xi7W frjon2oOmZTg0YsRbicic/Px1pqDeGLYPNzai72AHHsbb/SefnNxZ++ZuLvPNDSetArvrT+CdZFJ SMwvh9WpeXwwb1jodVyqAnaPG6FsvBo8v8+CNTAvXmiI0ryty//pJV99pfKcvH4ZG+CdJTtwS+/J aEfOz6koZ4HFVCYVXHIJ1osH4InfRXDsQdHF457CrIjvKnX1q8rVAWoFDXJfV7169dtaNWxYOyx4 zUxr+B6nPXQ33KepGCoPp7eYeVmaT4gzm4BIytmN5g1ll95e1iy4szxGf0fpk4qlMj1ErSuGjRFN nzWa5ZzXhDEiOWk/rLlnaQgLzMxkj5nC56SSbBQHdSDEKG2NPlzeaXtKYaN9mtXHYz0eHadP7te5 LEOvautVbCsV5yLva+qflOimaCBYH26hUoVoiJINbbUT8eXZsF06g4rkfXDRcwH9azeVqslFHk2E o3tYHH9ib2XSNVHm3+RdKdaHVkVed2sOTvyhzcGWECoiVEhlwZrsdlpK9Sm3ckqhJr9Rod43rCVV JsFJfvTysk+2wxG/G874YLpARH78RjPJzR67E9a0EDgKkgBLAW/aZqYcUg2aLEnRV31WSuV3M4+y quifoGrEe65br6RTXPpdg+vuCnoSuXDyWhWpYShPPGCmQLo0a1AzA2MZvGjWoJlGRp87djMKog/F dw/s+MIDDzwgwy479DeR66MBY7Ao90+f8G63C/u3HHOdopKoWHcYERpCCd0IVwTlzC8r16tYinkj nAr8m8rleRLegF5rNy9ZExVuRmTuOEZaCWxM38zCODXCflSk0A9OPUlUhcCZEV4pp2FPj4At/QyF n2k+CYP94kE4KPYLB2EhBUnsbFBNp9TMRo+Up/mkCbxmInum5t3pNypRdXIbP3snaW6n+0L4xsOv vPJCnZdeqq3ZY3pVWZ7T30StD7GXB2Fq1KjxYtqxHTGOMN5Y2DYaLAlRqUmw4Rso/DTo9YpvyqZE r9prVqT3dXsq7VeU62JI65JSNZUzXqIJiJv4t4TH8MY8saQTo3Q1BMs2ExZZH+4zEstrEV0+8Zbj FeVMVPnea3gbyrxBX+WYy6JzqWwlSHCxXE3ALYvfWzHp/eF9n3r00ZfvvuUWzZITDfhm00lvf1Ox 4lgpVuHsfe0aN2y0Zc7UmTalVKThcofxImGiBV48lPuoaFc4lShln2aLR7ClKa4zPI7iMHzL48mx RsHkVDcV6xWWocwR0RIeQ+VKMVKQRzeUsJPcuxM2ipnJaZQgZVHMhElSRoKmQxNhQrU5plIplRMs fyziSaGRRvRyebwuj3cTlaZXmKmt21jmJkaFW2FJ2OXOOrsz8YO3B/TX2PR1112nxIya4yB/1jeF 8G8q1bdJsTpYs/Hurnnttc8O6tWlR8Wp3Xa7UBvKm6RSRQsIkaKpgNNUhCbGn95JethN47WHit0B hxRLcYsuqFznObpo0fzdTJSnAYjmuRTPeSrJ5GHgPs3v1U1TaUaULMInP1OUhPulSJ9UIs6b+Yzl GWE9hXgeq3wNHqVeY6/w/i2Esx6y9qQBF/+2x+/05EbuuLRs7sRP6r/8TJtnnny0/o03Vn+a+tCo lzhV9kd0KSMvff2qUrXpIN84gQp5jK1UP2z917vdIbToUmSl2EP3wEqpiNjhTjzw/flFn3848667 bg9gy3bgOe0fuPcuf/7tf9fttwfcffedXW67+eYuV155ZedbatXqNf3DUXNj9q8/Z4/d7TE3Q7Q6 iUK3MrjFbOTNelHrSdQcYzZa4mYjRpE/U674jz2E5Zjpv1IWlQmKhwbRJaOoBKUsR2hUejlvg2w3 RsqWtM9dlnigfNeaOSvvuefOtn/+858bXXHFFRqb1YRYzU3V8KkQKrD93Qqtuumky+MElOeeeezh tqXHtxS7DQWwCxKhJaE7HMfXL1/30vPPt2VFNJVYSTVUGbXuEz8RzcTVb5oyrEr75ky/edVVV3VU Eo4bbrih+7QJ78yJ2LHyaE7Ihixb3G6XPX4Pb54Gi4ZMyf2Mwg0N/FxcZnI4e0jiLjiJPgdRaON5 ttgdjvzTG3Myw7dkJIVsO/fdoimLPhw77H1etzWv2ZJ2pDHroRdxfTOGxZ9SpoBVdWKuAOdT6F/1 AP7WphN93oGsnqYmS2mNbURqRfgmyl6b35tN2t900w0vsYKau60G0CxhGT11FQUXqpCQL9F3iVpd x6jSd1M0vVqKl9KVRFaT1ZXxRLlfWlHa3nPPPYGB/u0H9whoM7xHQKvhvbu1Gd6na9u3+vVsP6Jf 97Yj9L13lzbDJT0D3xzWs0u7IX26dxzcq1fggLp16yoFoab7q0xNuZYCdZ3nKFKiEKk6qC4ayVPd VHdZeoHrn1bmT7eqyjWGjCLiVqu+FLzyy7HPP/20ZtT7uokqo1ZVN9F5vsr8kug3HaNKi891DSld 6FBZmt4tA6Eb1o37EK+eoLntf0t0jI5VXeUO6f0JAUP8qLpWzejiA4CUqLqrLr76++r6L9tUuBSg m9eNq1KqnG8OuxDoU6hPmf/I5rsRn9JVnhCjsnXjPtRLEb9FqvYW1V3lqDyf8nxIrAqA3wWRf+/m u2kfynyVrNpV/lWbbriq+BTxW+Sn5/7Hb/9Vlf1j+2P7r9nUo36JIiR/bH/H5qMnKc5nnGQMr3jy ySevCgoKulaJvaok95L4jtM5f9DbL2w+ZUpZMqpXDRs27Dq9zRMfH/+y3ubZsGHDfZmZmR3KctIm lGdenFiWlvxxaU7WqAsX4movXbq01rp162oUFhY+pZdLKpPh/J9GdlWE+ryWa1555ZUblNktISGh tfXEnh3u7xblYeFnbrMQ0OzxnstZ3qZT5lBmfejGvMlurPjS4d61/pTTmbfiyJEjd+jp7L8r+9u/ c/Mp9bLvq3UwqIy7ly1b9nTp8i83uCd9kO0ZM8DufT1qADC6/y+/KjW2D/CuXpfi93H8PqYX8H5f j2fiYItryZSI8tio4fv27ZPf/n8CyVWRenXr1q1v1LtnvXv3vj/503f2u0d0daB/O2BgADCoC8Wf 3/n3IMrldH9VRWn/lMK9ahp3pQHsBPTjOX07eorHDkuzHNv/1s6dO2+oTAn4vw7JPrT6un/1GjVq 3Lhg/Njn4t8etLyg95tO+DcCAvUOGiVQ749VvocWwL8DGvN7pVR9B037fe+h6TzzHprv3bXKd9G6 tERRzw6etOHdorO/mBKgmTL/qoyA/47Nh1ZRwLX33XdfzfbNm9+zd3D3kcm9O6VZtWSLeb+schUb ZSnU3xK9l6ZFULROmi/344+kIX/TDEZ+tn+dn979milpfvNTVq0m/Lupmatb2K2d5eLY4d/HTQu6 Mzr6kMLo/+pNiBW3GrR27NjijldfffX+sAEdv8vr3sKtRQ3cVIamjOqNGjPpTZPlqAjvi3r8rimg 5m/+phdWOmm/Jlbru46lcjtq1g1FM9nNeZq+/xrPa8KyhXw2HH/TtSo6vO5JG+AXkzpzchMZPHoZ /3Uormq0NG5x/ZP33Xf7Z93b1jn3Vtdz5f6ve4wyfiZepQmJmp7v9NNcMCpWL+eZ9yTUCJpAp306 XspvSNF3Idg7KxwdNXmugTlek+3MFP8OeleiHrT2np3nXujd6VLS1I9a0JCqR/1X8XBVxd5wz003 3flB27avnerd+kiFkudJiT9TbOX7DuremrvLY/QCnvetR8349ilXE+14vJnQrPN4vBqkvRqAf3f0 5mA0LxHqGIqONy+9sFyliNMSC3qJMCWgsT3m/bfffPHFF2UL/isU7DNc8jFr3HTNNXcGvPDCi+d7 dIyx+zWBVW/mGD79i1J9YvI7kkNFF07yrabzm5UPiDgp3psZ1psV1uGnt3k0xdOrPG8ZVKhQr32d 6lDRL/Nv5ZOkkts19r4W0Nb7LoWyxzra1Udq1zfdZ0f0b7ulXz+6g6bu/7FbVcTWGNGy5ZO7J4zv F9e3a5rWvHLS0HhouPTOWFWlGhFf6sURolOvp5oubRT6qpnaX86/c/l7erfmuNijFS70aI0sehOl NFYWHqc1Ngw9qEGoRIcP4USq980fvbiiWZHiZU2GZoNpCU42RHZgy8KURV+8kb5ikQbh/yM3n/Ey iqXcfv31Vz0aN7xvbIWWWiEi1SWFQi8H/oKw6zqIWoO8Nrzpjs2RNGowCteuhi0yDK6LsUBOKlCQ DeTmAgnxcJw/i4qDwUie/C7i6HaVswHs7ZXtlMqke6dXXr0L60hoBEUPpA6n3yumZ6AdjV6bhrjY q1Nu/IwgPW/7j0OvFCurK69ATw1ue+S++544/u7g7UWBNF66SXXNtuq2lW+m/0SxMjRKruskwtID 2iB/9SK4tMhrab6Z1uR2aAEOpXrzmISnsHvM/C+4HEY8FeVwZ6TBevQwkkb3QWGnxkRmA9j8RSVe 4+ZuT4/EUIde7BNX620j79tEFr+GSBraI/W799+/Meh3XNHon918ipXVle9465C2LevM6+o/IDuw lUP8aKHClOfA+44tjckvKNfZth4yAlqheMUieDLiAU8ZzAQ772w7TWH0KtNqhcdeAeWNVsZYTdyz m/zRTuiFa3NMUT4sh3cgfmAgyhlgmLfZfQoWWtuS8w2axe8NYWV9tBZWKb+njhywLWXRnPt3jvj3 vJb6083Hs3qupSes9w178/WWKf06ljr1HpheV2rfhNym5MO8ISpbi3W5/OubN2X0qn8Zu3HWxLGw REfC47SYGYdaVVErP9kvJqB813oULPgE6eOHI++tvsgZ2h1Zw7sj/Z2+yPpoFEoXz0PpqUNw5mV4 54nqZRNnBdx5WShYuQyZvVry+nXZK/TyHg0b6+R127yGUr60eo7yDRf5vWGLGzW8W9CTT/7bXbSq PKunrndphuS+zm9uUo5ivbNrVkUmWuVKKR2AEGTSqNPA6YZzujRF8Q9fwVWYQ4Xa4HARlWWlKDmy D5mTxqCgZ0ez4LHeaxO1yGMw77BRKUooXiHEMTgo9KOBG9AN+V9OgiUmhDq2s3E88FjKUBp2FGmD u6Cc5+h1VUVremVKRk5eh+lJtANmPSYaubTOrXLOffRW631Tp8p2/Ns2Hx1oQOS2+2rVemJBn65v Zfm3csjPdFOhhl+N3ymfs5IOjB9bH7ldG6Nsz1Z4bIXs5hbvu2oxp5E29V1kd+dvnfTGut4bE0d6 G0ZvrPveWnfR+/AqysubDvKsunY2vYnc+VOBvFy4hWKHFc6sS8h5fyQ5mNTQtjGvT7pgrzHvCdPI eYX1astQ2b8eogf4LYyfO1nTDP4t6P0RHVSrVu2BD5o373C2W4cUvfTh1kJtClVZaaVAMU69EExv Qa+NFnZuh4rDVKy1FE7yqfLvF29fg1Qi2al3fBUW83xFaRKtk6YGMZ6GaSxvkgrlizaZ5fU7Dadb afTZMyx+jXCpTydYo07B49LKShVwZSYj9a0+cLWRu6dEFzJqMrT0IqRk44M3NDkXMjo1spz59L1n KxNb/I9vPu9AXefORrVrv7igi9+osk7NPMrtL9SaNSykXLlAdOKtUkq7usgNaIzCNStRbimFzeEi N1qQP3cGcv0VRHgpxPtuGQMBNoTe2RUNGMUq7OWnN4d7Za/QsSbsVYirBN1ysRRovIpLXRqhbPdm 2MpL2TEccKWlI3NYIHsEDW0bpXihqDdVpgTwyAfm+cpscmFEn7jY2Z/d8T/tPQi1isI0uUMTSR5s +vwTTRJ6t8/0ZuJQkglxrRRAdNCXlIul4MHaujFy6Wa59a4uvQFnXiYyPn6PFNCUBk5I1w3KH5Zy KxVsbvwvir0s5u3GygEfRV9UtnxkswqgH5XMMhzk6iI2Zsl338FTXEZOt8Jx7gTy+7TiMaIBBR96 j43XYDk6x6x9TBSXtm9sDxkxtNGWX1jJ/V+5VUXt3dWrV6/9fffAqQVddZPeiloCXjUVNLE9FW4n KuXYp48eDHdRJpXrpFtVgpxP34e9jbo0z2srhfhyJ3ipRKgUXxu+lUGqimDu17oNWijlcgisxtEn AxeTCoC+tQZvylhmwdql9EYKyO02lO5YT1+YylRZAoCuIVB0bMy6sh4Eg5PcnDJy4N6AgADZlf+R 4OKnqH1oWb8+E8IDO4Sr+zo7vMwb1tvh8gbkLRARSsdCJGUPakukxsNlo5tVUYGMmVOMG+YxSzcI 5S+Zrm2UR85WhiX1BFGL6ELUYBJdUIQ2jX7p9VGhTb8ZtItGqCzvuISurx7TjGW8hoLANijevdG4 a57SMmSwYa1CuRn4UQOpp8gv9hpJR6fmyAxs5j732btv/U+kY6kaiQm1d9WsXv2Z22rUaBzVM8B+ oUML5JPzHIqKiAqTfIJdT+lXSlnZ7FVLaLndcFrtjKT2oaBTCyqHN9ZBgylSEBUmH1TJLHizxgdV pEUUaRDdw+7t6czeYBrAq1wtW+kmpWihBNO1Dd/KG/F6EvJQjG9NJVqovPwe7WC7dMEEJ45LScju 25HUwWsF6LxKjmeDyUZ4/Kno9nURO7DDsmX9+v3LHxFV9RDMFNQODeo1XzNuyPGMiFCcS89F3pYf UGIQJXR50eBqW5eRT0+4SnMZyTrhyEpHUr8OVDobQghRnE8x2UGINpO7hjesXDlueQIMOEQxDvmz gQ1QwsYrpdKtajzyuauDVmT1Ilseg1EylW88E9MQ8pG1atDLjMZeR9qkUXBYitjQduSvWogSGjcX y0EbNQaDDfYy9SQznty6HjK7t0s+NzNI02n/pdSgwn1+rWZFPjGjd7e3z3w0yj7x2524qd8MxJ5L Qm7/Tqbl9QjGQVSWytE/tAMMEQCbFZlTPzEL/loYRDg60tiRQgxnGpdInNnQ+LYVneuhMKAh8np3 QtaQXsieHoTi1YtRvuV7lG/6BgXL5iNn0vvI6tMRFVSQzb+u8Yu1Hq9ZpkYoZE+SwsT7JqULDWpe QF0UblhtXp1yFmQie2hPw88upV1hL9GSIIrenAGkCfJuWafmjuPjhjTY/8HbmhH6L0GvjxLk95lZ 6ddee+0Ln7RuOj519CCMXrwBNfrNQ1TMRWQO7cIbYfdl93K0fxXJb/WGO7+YN+NA2anjyA+Qj1mf ilD31aeQyW7ZhmiUT6wb5c3lB9aF5etPYT+xFrakCBpBOzx03Uja7NbkbRpFl7UMtgvRyP3hS6QP 9oOF/KlcN2Y0jOUZP5gN7OV0KVApt15D/sDecFUUw2MvR8meLcgc3BaXerShEaPryB7k1pML1k2e jq1jI1wYO/CQlvLjff9L0FvVkOm1oUfmdW07dH+PdltS/VsiOeI0pm45goK4KOR3bUZ+o7dABZcR MUWH9sJT4aERK0Puh+9ULlPtRWsxJdufXV6BBynCHiAfuT6KO7+OnIlD4YzaAGfiFtiyz1ChLtiV yoUunIPflYfMQUVXOBkyOywojwpD+gdvm+wgUqozkD3BeAMyeqKHOrDRi6mgkvP8mqPw9Enk2e04 lngJFy8moygqEoWDOvPcxqQsuZCSxmbQ6UJgY2fK/DkdKvXwu28+StCQohJ+P/Ve3drDzwY2i7aw MmnvDELq9k0InzTS5DKwB1KBNGT5Q3szvreYxSMqzoehiGjVmt+K4y1Ufsm2H0wiiezR/VFOpTr9 iFgiK3XWGDhid1E2whO/Bc6MU3ClnEf5sQMo3LeZshUVJ/bDk3mBSi5n+cp9YwMKM5D+KRVMjq5Q 0jfRA8sFu7r416UkQ1R40dSPcPxsCp5+expqdR6H+7p8gKCF3yJj42pk+smQkYOpXG9A8zpKOjfC gV6dmw/6Fz0S+gklXPmif72Xu2d1fZPdsCFyaHULw0NQlJKIgtF9Tf6Zcr83kDl/MnmWXdluRfbc T+n/0lC01whZAxR0boG9O/eh+TvTkL9jHcrZFYvb1kHWgnfhSdgNuxa9TtgG17nNyN84D7E9WqGY 19KAj7VTHRSSTpJ6t0fxysVwaIlylxatYisWpiMj6F096WUD0rAZf7sOeVhZmjQS1wA5m9bhiR4f IGDW9zhyoRBRhS4UFxahvKAYxccOI7dbOwJAtCU3kJRChZ/t9ubbUwOaykv6XdGrlvJ5CfJtH37h vvsaRY5+K6yQHKlUqfl7d6L/9FVoNWY2UjevQ96Gb5G7djm7Woh3sDvjIlLJaTZxIVGhQZf0rq2w ds8p3DJkPs4c3o9sGq/iKaNhj1Z+my1wxKyHO2aHeT2qeOooWOk1KOOTHHxvlMa/DWc3RGaXN1HC MFfDlC7RRU4mkoeQ6xWByfto/5LxXoRELdtXNGcS4iJjUHSOXG4vg7u8AlHBWzBn40G8v3o/Cr6c w+PI2UIuXTrxb/KQztsiPxvfmvf/uypXhak7aDDc5Ljp2bJlwP6OLY5pafS4Hu3x7f4QXN93KkYt 24Zi0kDglCXoP38tihx6OdqKgu3fo1CGhRV10Pe0stLpXZtj9Z6juHnAbIQfPYachR/DEbkOrvjN RqF6s1LLUSjXTeH4vuapgo0G0tmxOUWJjcmjJmjQk4TXUejfBllfzWfkVwq3zQ1b3Fnk+IuG6D1Q yd5BJK+bWEGfObVnO1zo+Sbs2aQWiw0F9H8/3ngMftPXInf5AiJWobXcs0aoaN0AsX6Nk4cNC5AO fnflXg53Kc8E+bUfe6Z724RiWtey48fQfuZa3DzkK5y+mIMt51JQvfdkXNtzNraeSSQluJHxyUeo aMuuzNAyYUgPJH3wHsLo0H+x/QhuG7gYcQkJZs1vR/RmOPS2ZdwWopefMfz77EbkDetAw8LuKT+W N13RWn6tl08VtlaQImxsuOK2DVC+m0aQ13TT0GVOn+DtLf5NeazXTZOrpex4Lhq8kvaNkb5+pfIH wOa24+3Vh9Bz1g8oXDyTFOINZsx8B56fH/iaM2xEn3otH35YuvhdePenLpheT3qh1csvdLswtLMl +e2+yC+x4vZB8/HsqK9QUFaB4d8dw58GzEH1fvMxd9MBg4q8IX1Q3qklMiePQXpaHkIu5CEn6gym bjiO+wd9gwupcbAl0Bc+vwH2xJ1wxmyBNXEXyvKSYM1OxqVe7ZA2eiisCTFInfC+4WeXBoeoYBlH NxXuJMfLDbtENGqxwHJXBZyxZ5Hr7x1edLd71VCLurjSeXsYlpcGtMCFKR+azAMWRm2BX2zBkAXb ULJwGpz+L1PBivpeQVmr15DhXw97e7Z+c8aYMfKYfjflim81D0FR2cN33HHHay1eeaVn1IdvuS+G haHlZytRs880fHPqHG2XDd1n/IAr+n+Fa/rOxqrDEXBlZSK1bwekfjIBSanZeHT4bNzY+2NsjkrC 2O/24bbBXyE1PRaWuH1U5BlUVGTCURCPivSz6DXvB7wyYgqOzPgUq5f8gPsGTsEPa3cipycVRit+ OaWgnP+2ogrNqKmPzIWzoMUNPZZyZH3+IcrbMUIjHenRk9O4Wi2QxGAn64clyL2QCBd9Zi3eVWfi aoxdvRcF8yYyjFfjsbd1a46ybbuQc+6cOycx8XPNcKf8LsOQPr5VaylCefzqq6+uP2Jov9FxCXHu 1pPXmNRUWt4v31oBt7UEiVl5uG/kV7hz0DSkFJWgrKgAmbEXcST8Al75YAGqMdi4YtBCtJ2zEV0X rKfCpiI3MwlFRVmYtuUUBk1bhrLSTJRlJeO23jNw/5CZ2DbrU7y3YieuJj+vWb+HfE1DY56HyRdV uEpEklO9g+uNkNW3DZCXAysDj6yUC0gZ3ZvGkC4VjanWky3p2gL5kacRMPVr1JmwENlWG0pdbtZ5 HiZtPIn8aePMfIhslp/1/Sr68Kfw2KgF+PDrHaFUbM3fK8e5lOvzb++sXr36M7feemuTb7ZsWdp6 8ree69n1Hxw+B2fSM1CeRFcs6qDJxHRz/5kInPsDShhRjf1uNx4cugB39p2FF4NW485hi3BVn9kI +GIHGn/2PZp9OA+5FU68tXQP7un5GQ6eOQP7pQhYMqLx3OjZeGDgDGyePwfTlq/DNQyxv/32IPJp jLwT9zT6VY8cqoF2ZRp9DaU0fNldGqGUruHSgxHoMHERslcvQmGXFig/dBCl8eeQMOldHI3PwbUD 5+LKAfMxM/gELhaV4bpuU7HsYDQSV8xH+pJZKDh4ABuOx+C6flPZGxcRCNOyhowJunXevHm/yyiZ j2/1APLeGjVqvFD7xRfbd5mxoqRm19noNO17ZJSWoSg5DCXnd6KCHDmZPFqrzzzsT0jDHhq36/tP wYgVm7E7kqFxRTnmBZ9C79nrEZyUiTvf+gJjVm3A4v2RuKb3HAxdvBtluefhSjyA4tWzERK8A8M+ W4zTU6cjiT7z/B824+yOvTSMzYhcopZ8a7wAWnVLJ3oNHZsiq08n5Ozdg1XHo3DrwFl4/qNFKPqB AcL4EdhwIgIjl61lELIT87acxNXsdVcPXITOs7/H3phEXNd/Do5eyEZiajrGL9+NHgs34e7+09g7 5+DPgxfjnhFf2MZMmvHAmBkz/mneFWp/NAp2xRVXvPzBxxNG+b0/BV/tDYe1LB8V5w4z9NyLkrwU LDx8Djd0n45GE5Yh1+bAuO8P47Yhc5BTkA1LShQsCfvhKk6FxWrHwbRcXNfrc5xIzsJz7y5Ete5z cKGklD1gOxy7vkR258ZIDmyFxL7+yGRoXEDlRXduhQv+TcibDczjeYWpFW0bo4QGKrNHayQt/wL5 GamY+P0BXN8rCK9+9BXqfPwVkhctRsY3K9AoaAVe/2gZ0k+cxP74bNzAnndFvzls8BBM23kK97Kx heDBX23ALT2n4ZUJX2H82j34fP0BXDN4Jp58a05C0IJvHq6cvCf9/MObb+xWlHBH9epXPvX2wB5d Ms7sS7blJMKeTgN2dg9s5/YjPz8LQ1YewA09Z6HZx6uRQ8WG5xXhzsHTMGr1PlSksKvH7KUXsI2G aztKMmLRafoStJi0CjkWK+4btRjViKKj6Xko3bwCqQHNUUF3SQva28mTViKzgt5AIXmzMKAJiuga 5XRvhsyR/ZDx5QKkHz6ITBrOqRuP0PuYirv6zsTAReuxLuwcnhixABGJqdgdFoOa9MVvHTINx+Mz cD63CC++twL3DpmHNKeb/u0a9JyzFmcZpd0y4FPMP3COHoQDJR43ypwexOQVeZKycr7WOkHUxz+s XJ/7Ja6tft11191yww03PLR89meDcsK2F9kjtOgj3aUzwVTudlgzz+PdJWvwwODpmLj+CPIq7LhY UIF6ExbjwbdmosRmhSVmJ6znGRzEboUlfieiLsTjocFBOHwuDikFubh/9FJc22cBmk/6Gpfi45C7 cjlyPn8fqe/2R8Y7PZH+fn9kTxmL7AVTkL2ZwUn4SVQUZCE+IxOLth1Fq6BvcT0b56ZeU9Di06U4 mpQBB33XzGIL7ug7GXcMnozbSE+vT1yMFz6Yh9vpyTxEg3tn78+xZH84Tufkow69kpj8Ury1Yhse eXseAyA3XXSXWQpUobXN7USR1RrWoWfPm/ReHHXzdyv3R4rV6iR16tR5eNea1eNKzh9yuungu84G wx6xx6RmcUZSwcmnEXcxBZcYm5fmJiC9KB/PvLMIN/SYhmmbDsOVGW2y4Fljlc1jBypiyasluYgt KILNWo4yRnGDlm7EteyeV/efh6ffXoRhs9dg5obD+O5EHL4/GYvvjkdj2vZj6DN7NZq+Ox9PDp+F W/rPwhV9pqIa0Viz+zQ0mfQNDqfSsDqsJgVWCa1/rtWBMCpu7Lqj+CEsCcV0z86TehYeOIOZ20IR V1gOiwc4m5VNxBZh74Uc3DZoLt5afRA2j8ubAs5jZ3mMNIliu8ORSWN29yjvat9/l3J/pFhKrdtu u+3+3T98PaLszKEK6+ndcEdsM9nwnBHBQMQGeCI2Er27iMxjKI05ioqiFHSZvhy3d5uEredSYcu/ ZBaGdZzfZdaxtGusIHYXrFkxZmKdw+VAhc2JQqcDAxZuRHUq60p6Glf3n00kfolr+nyBKwbMw9X9 vkD1AQtwZe955MkFqEFv4/ruU3idiZi6LQQXSyyoILKUhcxm53e7g0ZzOe7pNxEZFicDMCnJxVBc WfD4HxVPt9ZkkHbxu5ad3h2fijt6f4KaXcbj9KVc/lgOc5Dy/9rz4M5PQ0l+sodu44hl06bpgcFv Vu5PFXsT/dl75372UUdL5AG7M5SIDaNCzYK12+CI3AZ35CYKw9Qoopd/WyJ3MKzPwobIJKTlFcKe eREVcXvIs9vhOb8XiNoB93kqN5rH5UTDTS5z8E5dyq3G/xXYbVgWHmMQeHfv6ezOM3H7wNm4g8q9 u+8c3NFzKvlzNnot3oa5ByJxLDkD+RYlY6MeNBHP4yDSXEaR5Syvdr8PcF3fSYhJzTJTyHQdM6lP syX5oVSHSjpo4w+Z5Q48PWIeHiRV7E/OZgAixebD4yiGNfccvRf2VN5LWeIhFF4KseRmRWi9T+nr N21qBZG0PINajz567wPfLZrdPT/8QLKyMSm/mOf0FqJ1I5G7FfbIraSHrVTuVnjObDZ5xbSMsSX2 IMrollljGW3xb2Vpsp3jMeeVZ2yrSUvoJi1Y4nfDkcVK8ybsbhu7oGJ75WSk8G8huoDoy6axy2HX LrA7zaLQGiR3UkwqQbfm3ElRxJ+6sGZEsrmc1LaTPWFf3CX0nLUaFrumnfIc/mo2otGsQAyboQ8b z/tw2RaMWBKMOHKunRTgKEmGJT0SNirUHs97i9sNT8Im2BL3Ijf5ZPihnRs1xvKblCvF+kLcG594 4v772jRp8nLeqZ1xjnBa+LA9Jo+YJ3wTP6mcCCoqQnkcN1KUy3GDN+0V0etRbrHLuRx57LmdZtjQ HbPJJAEyecVID57oLSY5mu3SSdjLkuFyeNeN8BBFNCMml6PLQ+4kItWblYPR5GkkOqUQ6pfKNGk2 zT4lyDS5HvndScvupgItVKBdKBVq+amGY4EU/m6OZ1lsUI9TTzPIp/Yy2HITYU07BVsS71fZn5Sl T1nzYnkfseyxiQfzN36z/Fm6YgKhlPs3fV0fHVx2uWrXfqx27NHNWxzhuzyu0GC4wneRDrabrHi+ bHg/Sjd4OY8jxWTD42/Khneen5UZ8H4srDQ/3RqzTdwG64X9cGacBcqzqQUaDmFMGpEoMaY0+Re9 cJ9XhD51a2+STCna+7eO9R6jvk8Roil6TGSO0XlmPi8bhVzrsRfBkX+Bhvm4SUnoTbGldFoEk/Kl U7lOejnWpP2OC6E7P/9h2cKn7777bgHxV5Ur1IpnzcRlegePzJ44rmfpGSmWCgihksJ2mkx4zgjv AuH/rHJdRIFJlJmgjHRKkrnFJFKzKt9iVhTcpRk0IOI8u0+LlVKpMH2v/DSJMauK/hllCu5StFeZ Wp9HFCJ0mzW/lb61JA327BiUkkcdhlN5v+xNSsGFWDZ8HO+B3o3W+7Ym7PGE7loz8Y477lASJA29 Smd/kxakdR8dKFvTvbfccstziXs27bJrreWTyt/ozTWmdIP2Kkky/znl7vDmEyOXueNJK0SJSSsY ywaMo+KTDsGWGgYnAxWUZRNZpV5EkzZ+tCi6sokStRIX3TnvAuma0Vh2WVyOEp5SDIelEG4q05OX AHd6BCPFg2xgUh6vp7yPuKAsfbwfKlLLg7tMgk56R0SvJS644sC2bycLeNWrV9fDWQHxV4MI/fgX Onjssdpfz5oypiJ0rxMhvEAoDVUYeTKU3BomQ0bv4JeU+6MspFTSryjXZCDVd5OBlMcQLco+qnUh PFoAO4HlKH0gv7vi9pL/DjN0Pglr6ik40qn0yiyk9vTTlRlIKZczkJ6GPeWoyUAqsSYduJyF1G2S bbJeWndC1xSXmvyQDIi0j3640hmaJHHxO6AVxfOjt+etWTZ9bOMGDV6oVauWIjOhVjr7m5TgM2Ii Zk23v394325tkvdvO+MM20GFMgojWo1yQ4Tg9fQW2IWrKNcoluLLQCrlmqTDv8q5lTcST1HORZNv UcLvlShWqkDlsVWaVaUa9KaApdIlSjdIUfpCLYXuXSmfXdrkc9xukOjdL7rx7WeZVdIX/kVULhuU yhVqXaQD5YW0x2xG/vk9KcP6dG7foM4LyrsmxephgXq59ParqBVvGNReddVVT/q92aK9JXSn1WQb JS3Y9RnGSoVJuewuSpT5OyhXK5a4eOPK4Wi6orplAnuJ4V/yOm8YQjHpQxzoTaLJT6V4rcxe6k3x yvIM0tRA3l4gUS7HH6V3lZgGqbzWT4UKVaOZRuRxFno3MYfX7H70wQdfe+6pp5TRT26XaFNA9NHB X0VtVa4Vah9YOWfm0DPb1m91UalOKtETth720/rkDYSzNU+zYqF0RxhA/C7IlVtmboZdk9ymh5HK JipFKIuoQXUl/xkaEYXou1BtlKR9vH4VBP4YkT8Vb9k+Rbu5z/fdxR4jtNtZh5yzuzJ7B7br8vDD 99UhDShrnw+xPsX+Zg9BIZxZZ+etbt06W0/utrtIBe6QYFICFRjGm6HHACpYylV6bUjk855hl6Vo 8EbjC04FFFE89hxv0uQpZzmV+XPl05rcuT4/VwgU8sxN0oAlenPnOhJZtlGElFuJRqLTqWOMd6GG 0DFSro7RZ1UFekWJ29Vghr/NPh3HnqLewu8e5c5NkqdCj4A9xZYYjLLYXdb9axctbvdmk9bXXnut 8kEqnaHmw2kcu6pif3XTQb4HjveysOc3Lpj5ufsUlSp/NoQIpWK9yuVNUjxUuiOCfCZ3TF4DEesV dl2KS3lzz1PJRK7GENzneWNStCIzDfYw5FXeXAUUppsLiYZbpWCWoXSvfwV92u/t1vpb57BO5GYz YaQyybArkVRAMVRDRF4+31yDYihEdLEVNiOsKwMFW8J294HNX60ZN3JgPyL11fvvuks0oIew8gpk vNS7f5UKfJuPEjR+YCZ4fPjW4K5ha1ZsdtDl8hoz3kwYOZCo9fC7k2iVKyYFuyJ2EbFKTEzHujIx sesMFRDJrhXF889zfzSRQ+W6K5MTu0UVlcmJTbSmhOvq0j4xnFqpBJ9SfiRSZqUYxHpRa5ISE3WX ExNL+Jty6io5sddIehvHIxePnoGTXd/Bvyvidlv2rl24atTQbv3vvv32hk8+8sgr1IXe/RUNiCrV q+UV/KrxqrpVNWRKkPnkW9279EjbszHKTqQ6wmhIlJyY/CpFOxQ8hO82i25YIoI9WaF7c06sX7k3 eMX89Vu+nv/dmsUzV61dOvfbrSvnbdi/ev6Oooid+c5zUjDPF1pJCy5yplshr+Fb3rTWjTBdt9LI UBlIWE8hx/5MsRIp3Ss+FLupWMTTRYxfx/NkCGnpiWBnoiaTeHuC9zhe1yh+C6xswLxze7I3rJy/ 6I16L/ldd911Da688kp5App7q+BAD2B9NOALEn4TYrXpoKqUYJIT33fXXa2sp3a45Hq5wmlYwkQP u2ENoY/J0Lcicrsr8fCGqJeef7ZHrVo1/OhZtFPW53uV+fn22/3uvPO2wPvuvrsbKxp4U82aPZs2 rDvy0Nqle4rP7ilTKKkxBCdvTBGQXDCPsc6K3SlUhiI0ZX02qbB/QblCnzcklXiR6M36LI9jE3+j EeZ3o9xK9KoX6Dil0bYk7XdeDNlwZvTQ7iNuueXGFldccUUDivIGK2XsAxRxq7wBBQfSzW8yXD/d fJSgljFzEOq98kKjtYtmz3GY3ORUgKiBCraH7EBZWHD5mR2rd91cs2YbRibNKHqrW4mAlWj4tcpP /f0GpQmlBaUNpcONN9zQ9c47b+99cvf3R1NDN2cWRW2rsPv8W3ZvodcbPAhhpBCK0mz/knK9ywp4 P5V5X9wpBTpZnkvTnahEB100B5XviN/lKYjYVJx7ZmtG+I6vd+9eu/jrRx99tH21atUaEamqs5Aq pcpgqedKD+rF4taqaP27N52kVvHN+Xpc+cqPf/vVZqcMF70Ed/hmKdWdH7Ita3if7gMef/hhpccW Hz1PUaJgVcyXTluiv7Vfv1fN8Nzyz3/+czuK35/+9KfOXTq1fnfd4qnfZ4VsulR6dlupnaGn43Ja bSqXipGyf5pOWyK/WEpVJOUibzqIRruSu/O8snNbi7PDN2ZmRe5MO7Z9xfZl8yfNefG52l153ZYv vfR8u6uvvlopvlUvGSolNhZSfUr1UUBVbv270Fp1q8q3Im5lU66fe2xHul2h7omtKDu+3hO147s9 N910U6OHHrpXucp1jIheFlTOtLqQGsYn+ltliWKUD1zKlivzKkWoVupr5S7vcM011wRQ0YFvNKw7 LGjMsM/iT24Lzzu/Jyfn7Na8isSdHmvCLo89fo8nO2xDek74xrT8iE05hWe3FhZGbS8sjt5VkX9+ b25h/OGc9KgDcYumfzhzzIh+77Vs3qgfy247Y+KY97oGtuvOa6kXCaE+QKg+qpc4VfX1pdf2KdVH Af8QWqtuKkAF+ibUKV11/Yv7Nkba6NeWhW9zh65f/s2jD95T/85bbvH5ejpObok4SefJigr5PtHf 2i8Ol/chVEjRahCVr26ofOKvU6RojeC3pqLbt2zZpF/3wPbDTM7yLq1MvvL+3dq93a97+5/nKw9o M6R3lw5DevfoNCggoEPvm2++WXnPRUU+ZaoxdS29r6seJYWqHqqP6iWUqr5Vkfp3Gaxf26oqV2hT q6pSr1tCt3kSj2w9+NJzz9UjVch6Sqm+SsltE9EL9RK1tk98+/S7jhMq1BBqEF1D3VDdUdShmxei 1CNEH+qyUvqviY7zcb0aSmUos7+PqqRMNaau5etdqrvq4UOpz1D5lCqF/i5K9W1VaUEVUIWE0Jfa vFG/ScO6dV8mIrRPv/mU6us6Pk76a6IK65iqilYjqhvKxdFNi1qEKClbCvl7E8LrHJ2rMqRIIVPl qrv7lKlr+hDqA8TvjtJf2lS4FKUb100rU72U6avwT7Ps69jfWikfEnSsbkbnqmFUjm5WN62bV/lS thpQXVbo/jXRcTpeonNljFSWAKC6qnzdk65VFQxV6/4vU6pv0wV0UbWoKqVK+m5SlVaFVVEfJ/0z La1zdXOSqooWoqQIXUd8rXr8mug4H9frXJWhsnQfP1WmT6GS/9HNhyxVRhXzIUqiyqvC6ka+Cv6z mw8xvptVuVKCRHWQ6Hq/Jr5jJb7zqypR4ruW5N+2+W5WFVTFpeSfctO/qoJVFeCrx2+Vn54r+Y/d VGEp0ie+m/hj+522/xok/LH9sf2x/bH912w/ZVaf+EzYT03b35Kq50h+WuYf2x/b37VVBU9VYFUF nc/7lly5ePHiGvPmzbvh4YcfriapU6fONePGjbs+IiLivry8vAalqTE9LVGnhlnCj75tCTs80n6K nyePj7CcPjXMmpHcu7i4uElaWtrDWiNgxIgR1ZTGXnL69OlrJUppX5nWvmrdJH9s/4e3vwZQA0qK oi3F3NWeeeaZ6pKvv/769sOHDz+yatWqe9esWXN/cnJy+5KSko8qclMXWxJCl1lCgleUH9/yje3Y 5q2Oo5vD3Ic2pXn2bij07F5X7Nm5rsSzwwi/ry9wH9qa6ToaHOE4sm2H/cTu1faI48vsieeW2Auy F5aXl48sKiqqHxYWds/FixfvLSwsfC0xMfEWJV73rdFQBdB/bP+Lt6ps9bdAes1tt91Wnexp1g2q Xbv2jY8//vhN0dHR7UqPHVhatn71t9bl8w+5ls/NcC/4rMAzc2K5Z9oEJ6aMBz4fB0waCXz8FmWE V4LerhR9r9zn2z9xeKXw+E+475N3gE/HqByPZ+p7Ts/MD8o9cycUeZZMynCtnH7UvWb+SWfMia8J 6s4zZsyoLtHbnZLK95Or3uMf23/55gOq5LKJpwikGsO6RiB99tlna3bs2PHWAwcO1AsODq6X/e3C T6xT3w0rf29AqnVMP7vn7d5ujOjtwVu9gOE9gGFdKV34XdK5ilTu028+GfoLYs5lGcO7AW9J9F1l Vsrl4yr/1u8j+feorh6M6eXCu4Mtno9GZ7imfhpu3b9jDJn/Mb3oqWyJ27Zt871or3v+Y/sv2n7K qj5GFVA19K6R7RvYyLd379797iVLljwXPf3jgcnjB+7NeCswpWRgR4uzdzsPer4J9GhOaQnzvVdb SntKB/6tT/7dszVFv/O43vzs04qfEh5vhL/rsxd/0+9GKo/pSenB3yUqp1cbb5m9Je1+LOZa/F3H dmN5XXluV352bwtnn06ekiHdLfnjhl4omPrR5rI9GzumpKTcf+zYsRsPHTKrEkkXfzDxf+Dma5Sq zPojsHbo0OEmMtLN11133c2dW7S4f83IIa0i3uk/58KAwJO53Vvnlwc09SgnLTpp/QN+Kv+Asnr6 NwH8tMyV8in6RH9XSketstSMx+uTv/nx3N8iupZykHds4BXlOpCYffqN11Z5uq6fpAnc/FRGUu8S WyqHn/qN9fCwTi5+WgKaIb9LM2T3bpeXM6Lvgayg9z5O/mrOqwr8xMIMAqsx6JNu/gDxv3nzgfVn zFqrVq0b6tevf8uTTz55+2uvvXbv8r4dWh0b5D87YYB/VFb3duX5nZp5bASEi0BSnnUBQosvuTs1 JRCUg5fAVE4zAbmjgKzPSlB1oLTXJ4FjACYwUXyA+2ui4805PM6P1/QjaDspg18V8CrVTHvfdSk+ oFbmEDZrwnXiMaZDNTX1dfs3gyewGcHrTRCq+7B0aobCwFburJ7tSy7273Qi6d0Bo5NnTXg2evfu WimHDtVcvHix9PXH9j+4+di1anAln9W4AVqR0b9147uGd+7w6NttWz6zZVjPgdGD/Y5k9GpVVNS5 kdtOoJo17UxWF4qSPhlRVm+Jss4SKAJPJYC8v3uP8a6uoGR9DQgUZZWtCjhvmR4CTnlAtYCARH8b IOp3k4/Te5ySTit/qNbQ83QiMDsJmD4RoFkuj/GK9tWlCMDK/qVOJhYWgNUZdA0drzTCr/E31o9l a4kOe9v6KPZv4soYEJCTOGrAN+EfjnljXVDQdVumTbuen+rsfzDwv3D7KWB97KppI5pKUuuWW265 /c4777ynZ5O6z28a1Gl09Dtd0lK7NnaVaSkmX8N2ELv9miitvDI6ku0qV/YxOUq5X8uMSAz4DRBZ rjmG4Gkrlqbpbq8kXQQWwerNvq7jK8tWjlQlCTfJaH2AF6h5vmF5lmX26VgC1azwVoffdV7l8bqm EW8dTLZ2lm0WeTDnecWbgpmdrF0DONo2gJVsn+vXzJ3eo0152ruDI86PG9Fo88iRNSuH1qTbP7bf casKWJ87cHlCmvzWu2vVuuu2GjXu71j78ReOvz18XvyA7hfT/Zt6LP5aQkorLikVqTeH989B+nMR AJRd0+GnLMcCgBcsyh3ubq9s9FqetbHpDFrnxqyzQJCYTPR/RUw5KrtStE/5xc1CF1V+V/J2bz0E Qn2XKCmlWN6bnNLkDtf6kD5QK0eiwKr7Mx2AYpid52opQ5M1VAD3ZoR20moo93l8pyae5BED9l6Y 8EG3tf3719KoRJB3BZI/GPgf3KS4X2JYAVYMK8De8uKDD95b//HHHx3dsmn9XYP6TbjQs+PFQr8m jgqaZ60b4aL/5+jYHDa/ZgQhQSeWNKD4dZELYJYcIxh8C9Qp+7/EANYcR8AQPB6CSEDXkmROnqPF RJ1kQQfFTkDaWFYFfdpSdqTiQErnBqjgd7sSLxtG9l5Hy/B42fYnwnJ0Pe9qLHIFBFaxsE9UDwGc xyrJPjuZVtMyOdjNb14Xw8OOoMTNsgguio1gLw1oiKzuLSsS+wXsPjd6eLOYT95/NXv5V69mLl58 7zovE/+x/R3bXwUs5aa77qp1d99GjZ6d5O/feN+QAZ/FD+sfk+3XwmFp39DjXdeonmEz+aFmfU/D RDKzPwfoL4uAQrDStCpvvV1gNL6qQEFAtJbZfQNyQQoDGiHXvzGyAlogu5cfcoZ0R87oAcj/dDRK 5n+K0hWzUPztlyhas4SyHEXfLkfJ8kUon/k5yiZ+gIKxw5ExrDsu9W2HS92aIqtzI+QRTEWsfxmB ZxOgNXJAoJm89QzKbH6skwnC5GLwvrQapcTco+ou0KpDyF2RpeE9iaE7akGZV7wWhWWZdfh0HO/J 0u4Nd07XtqUX3x2xKSHo/TdDFyy4PWTePLlgf7gQv2GTkqq6BT4f1gD22muvvaNR7dqPLRrQveO3 b/cbcmqA/76Unm2s5TR5ymTuCKCQWVwyjW3INlqSSUGN8Q/ZeL8CXMNIRgh4+bQCC1nbSiCU8vdc SioZN7lXBxR99iEqtq2H7VwEHOmpcBcVwG21wGP3Lk3qcjrgdDnNSpnK2KM0SWZVTbNUKb/bHPBY rGbFIrelDJ7yEngKcmC/GAdrxAmUbViNvInvIqlbO1zs2BjZ7CBKjW9h3cToWi3OxnvVQmNmKScD Xi9zyzoIlGb9LcPa0kNdWoU6BH5ds2yUWF73J59cvrWW3lMnLwxo5rrQr1NW5JjBs+IWftEiZcnC OuvWrfsjgPsbW1XA+lhWU9/1PtZtV1999T1KONPm5ZfrHv5kwoKz/f0ysgJf99jYEC5/r3lW/ldj dtUo/G4CGDbIzwKknwp/06dZ8ZPioJSyI+QQLFn+LVEybCDKly2C9eQh2NMS4CzPh8NRbtI8KemO myKgmhRxLmUy8pj0ex6loVZ6Oe1zOAlYipZrIXjdNhs8BDi0DoNSUimxn8cFB8HvJvi1fqRyk7uL S+HKyYLt9CEUL56B7OG9kOHXAkUEZgXrZwl4nQwsIMpV0P1U+rJGZCW892YALH20rZTLwebrhr0t PM7aro7x6+XSpAe2cF4c3PNU9qK5/eX7ao4E2+EP9q2yVWVZAbYqy+rlmDvrPv3o4/4N6ryydECP QVHvjziU3q2jw6LFOtuKbegSkJGsZA2tZeagWXXIx6W/aYa32DhaKVXLe5k13WmCvUEUG63SpBpz yXIquK8wsBky+wcia8onKDt0EK60i/BU5BGYRSTMUmJSCTmV94xCsHrsBF+FBSgphicvA66MVNhT kmBNiIY1MhyWowdQui8YRXv0CvARlIcfhSXyBCyhR2GNjoTtYjzs6RfgzL5EkObBYyP7OnkNAtqb zstDcFOsBLeFnaU4C/YLZ1Gycx0yPnkfOQO6obhLSygQ1UIl3nWJeI8CpUY1CGAz5qyREbGyAjYe Y1YToD6MW2HigcrAjeztDSjpqnR63Z3Zs21a2qQPPk+Y+ukT5xYuvPGkN1no/2n29QVfkqq+7GWW pYhlH61Zs+YzM9o0HBbaq9WJ3MBGLjt9MrkDSltuku6TTYz/10Hr5RPQ8uu4zxfQeNiQEn3X2vd2 Bit2P/mpDVFOKfZvirxBAcid8RFKD+6AIzOFZr8MTqfFpJjU0sQeB0UsWU7w5GTCej4Cpbs3o2DZ l8j9/CPkjqVfO7Q98vq0QF6XRihg45cQJOVttXg3gzP6nrpWGTtHCX8rJKsXsLMUMGgs6NYa+f07 I/vtAciY+B6yF8xEwfrVKDu2D67E80BhFoFbRkK3krDt9DScJHqCutwCW2I8inZsQMb08Ujv3xYl ga+zE9MdaEc/nyCUry4QOzUyYQI7BWsaZfDqRGtRaSk676iG9ku84JUbYm1X35PTrqnjQv+uaw8P 7fnErFH+14wYYRba+j8LXh/LVn2AoGDAvIJ49y23PNzuhWdebVb7iYYbe/gvienS9lI+gw0xp1tL gypyZoNomEiKF3P4xAQpBIsZpjJmkkK28ZB1BGYPfb0KslNut+bI/vhtFG5bDWfKOXjKcghYAlOr VYrxxK6OUngyLqL0+D5kf/0F0j8egUuDOiK7S2MGUAQly3aoI6nz8LssgMRcx3QcMVqlmIcXqrNW L6aPSrH6ydRrxELsKGkKO/3OUvqfuf5NkNGrFVLf6YaMORNQGLwWtrhouEvJynQ7tCahVotzKy9g cQFssVHI+3450scORR47g5VWx6U6dGKnlohRVQ9ZGbKwWbGI9TEPU7hffq53FIN1V8enj+xp14z3 0QhFAW8gfpDf3rOj+wRFfTKuQfi/YfHef/fmY1rddNUATC/06gXhu6pVq/bwrTVr1n7mnnvqHxjU c31q93Z5JRo7VfAhACq611MjEzWLbQXYSmatNH/ehw06VoEJhcyn5bS1PF9m4BvIDhqOir2b4M5M JQi8zOpUvlm7lSaZQVNWOsqP7kTarI+RMqwrcru3oE+p0QX6k/IpDfi0tFU9go8MLtMrVq8E7o8A TFB4n4KpPhQDFvqWYjX+7hLgtWQLO5xDbOfXiH67wMb7I4DMMoQEXbGA3N8faZ++h6J1q+FKioOn tJg+sZWBIK0B78Gj5bXSU1C6ZS2yP3gLRYHUm8puTZ21bcaymvO6GotWJ64MWs2YL90JimFo1VE+ cFsCW8NmWuGEnT3f/w33xW6tQ84M6z3m7Iygp9fOmiULqbb8X8++vwRaPUi47BrcdNNNj41s2LDV d927vn9yaP8NmZ1bl1sCmngZrTVFyxeysbWsrMYqFXyJHUxQxk/9rU+No3oDFgZvjKht/LsooDUy 3xmK8j1bYc9NgcNWQrCy0a1krwoGU+V2OOLOIe+bL3FpZA9kBTSg30sgqZOYBxAsW+O4un7byrUq GRh6/MlkdD3s9DOdfmJXgZCgpQ+uRZ59Dyi8DKzy+Mnj3QSEMc8060Y05srfNI9Bj4FdZjRAfzem a8Sy36wHV+t6xg0o5b1dZGfKmPURyo/vgZv+tcdWwfupdG+sJbBHhaGMAM/o44dyukN2dlp7xyaw +DWFVfWQ6yDXgBbD+5BFdaRe1eEFXLo6jva0Th3qmCUuFROUdmjgSe/WMiXpozFzkydPCLw4M+jR nSPM2sj/a8FbFbS/5M/e+8pTjzz75dD+PbaMGfFp6LC+m7O7tHGa9T8rwamGN0GVTJsaX8wg82ZA 1RhoTZZqpTXt3qAPS9HK4G++Zpa/TH2rO7K/Xcrg6SJNa7lZ+sHitMHK4MpTZoHjbBzyZs9HZq8A FPk3goMg1LW8w0lyS9Q5dN3KBwAa+Nca0G0FOi+zXn76ZVisUsj0VYFrnpgJjCrXRPcKnrz3Z9wb nUuQ6OGG/FHfaruqi9eyCMx12IH00KMuQVgfOV2a4dKYgSgN3ghXTi7cZQSwzQWnhe5OOa0Ig7+0 LyYifRB94ACNQHhHThyyCuwEAq9WQPMtlex9lMy66V60zzxoUd10fa0s3BAZnVsVxX80dnTKgllv Ji2Y9fChoCCR0P868P410CqFhhKpKKnKY8NavNH+vXbN++3t1mpdWo9mDi0ppwY2bEeFudhY1oA6 pvFlVs3iswYkPIYmTRG01vwz/hpNnqNNY2R1aoW8+Z/Ceu6UN+BiYOPw0C8UKxVloeTADqR9NBYZ nZqZBpH515iwzLd5nMsGU1CnJ2MSb7DHaxph/czEF4JYjeurjznXK5d9bB+QfWI6oheMPndHFsRc s1LM7+qovKb3ugSZnoIJvL7zzBAe3RX+ndeVFmVAV+StXAxLXBRc9lIGchQHfeLiPJRvWoWCyWOR 25WuAl0VNzuVWNVYBzGtwGssAK/PDqVVOM2TQHUeP3YU/S5QU6/Odk3dKV06lkYP7PNWxEdjXjw5 fpTyuvyvcht0MxLfcNfPQFurVq0nOzVs2KjNa6+12t+544aMrq3tFplcsoOWj1ZjaWVkhxk8l+mn 2SRA/6JoAUGge80o2EGAF/q/hoSB7VG8fy1cean0A8mqNkbkFP4PzohTyJz8IbK7taEbQfPfRmBl A5qphmKeVyhkNrGegENgeFnRy/AaIzXjwwp0KF5/2su63uEkzUXwir5r/2VGpnhncLG+VcR33uVj fYDnvXnBrQ7qY2YBjseJrTsygNLKpwo+WVf5wulvD0DRvq10IVLgshaZhx2oqID9YgKyF81CfGAr WOg3O9gZXASt92GE2F9sz7rxfrTKqUZp9Ijbdx8mgGzfhMDVsGMLXOjVqfjMkO7jj6z+6o7T3y2+ uXLCzn89eH+Vaa+66qrHb65R48UHb7ut8fq+Pb6J6+qXXspI1tVajSKQvkQwEYz+DIQCqNxATZxu TP+QiqMinWI6fmpCtRZMFsgKOzdDxidjYL1wzjyV0pMql1a1tjsYjKWj7JvlSOvXA3lUvFWgk3lU gwkUhukEIj1pkokkiNuRUeUSyPUgS7nayMwSbGxcJxtSAYxHk8nF+ixD67Xpd4eWxW3/KkGgDqAO qOuwvLZyM17hfch6sDNyv0y3ZnGp/rquOowZmhLDVXYWuUUCkRmBMMGV6itAe/cbYLPu8v8r6Mdm 9++C1HFD4UmMInDL4XF6GHy64C4sQPnp40gd0QclDN7M2sY83zufVx2GdWanFRt7wazfvWB28x7d bQlcBclvvkIL+Doy+7YNPT28y/DF7wXU+Dqot1yG/2rmrQraqoGYQCuf9r7bybQf9OnWac3kDyd+ HTTu850j+2fEfzkLFSEnYI0IQ9GKBUh5pzdyNDZpgKRGpkKlQInMp2EmsgOVbO/cFGldmyNzVhCc CWwsMqtLq8no6RUBXH42FJemf4hM+oSaYCLwexT4yT3we4Vs/gojek2akQ8r1pVp9rEm2V0Av+zT en1vw8SaFM466uGGmcRCcRkLoM5GUMrMtn+ZDc66y+fVqIgBhdjUC3qtkl5B8Gj5YpfK033pmMqR Be8IgERsrfpQdD1ZHONCyPpoP6/NTu7ida1k8SKWebFvZ5Qf2gl3aYFZF8riJnjLCuEIP4a0d4ch m9fUsvQa5XAT8N7Ook4jHdDaGVdBVo/XU13YiWTxdE1361dR0Ol1z8W+7fdcXD6/aerqr144tnCK 4ha1/X/lpor7xmkFWg15XR49oDza8qXnXu/VrHHHjwPbjtn17tDc7MgQ1+6TEej7xVq0mbIS3+49 ifQzZ5E95SMUEGyKsr1vITShsHHIhk7z2RB2suKlLk2Ru2wmLEln6cvSLOpxLFnWVVyEnG2bkDJ6 CHIYeNk6vkJ2fsWMNDj04IJlOv3qGfCaNa0FEAMqClnMjFiY4MjLiFYGRNZAzfxioNK2LsoJZisB ZqX5rKCU0LzmB7ID9XgTaf07IG1wIDKGdvXK4M5IH+CH7B7tUBDYGqV+LQjYpqwT68FrmWE0AtJO /17rcNs1BGdcIq+75FZwaEBKEYv7pjcSYOrQmjyjUQ/vgxYFYWTo1nWQ2qsZctYsgCXhDJwVepjh hsdmQUXkCWTPmIDsALoacjs0u6xt00oR0wugshhet0kdSKzs5P0rpvC0Yf3Y+QoCWhZHdm2/fXf/ /g+fmDHj1rV/WY7vv4Z5fUwrEdtqqMT3CFfjtMpsqcSRtRs89Xjzeb27fnxg3IhDyUGj3YnhYRj2 xTrc2HMaavSdj5eGz8W56GSkrvoKmUO70CeT2ZIvRgCTIWSC7fRFy9iY2d3fRO6i2bAnxsNls8JG 0Doc9OsK8pG/cgmyBvdEkcw6Fa9JJhb6sg6ZRwV0GlPV3zKZagxNCmcAIjPpNcnyKcXsXuDaAwiq znVR0PMNFI7qjOLP30HR3CDkLZqOgo2rzMOKipizsCVfgCstFZ7MNCA3A9CQVW46nJmXYLt0ERUX 41AeeQpFuzchZ9kc5Hw2GhmM/LO7NkBpZwIvoIEBn14vchLImkdgmE6AaiPXQfXRyIOCQ4kA7eto vA/6ou42XotSwXOzulFHkyagIvQUnE4bHHYGqdZSWM+cRN7MT5DKTl3OTqCVVS16dN6+udGBr5N4 p1J6Yw7D9hrJaSeGbsy2aYLMbm2y4z8e9V7o+HdeWj2iux4m/Vf5u1VdBJ9f63sipsjzQcpTvRo3 bDWiXcvuKwNbLzjbp5P9Yt8AlIQexTe7DqHttNV4aMR8NP1wMRLjkpBBQOQO6Gj8KXvlUJCA6yGA 7TTfBX1aIXX253BcTGcA4oKH/qwe0TpzLiF38XzkaByT4NPDA61obaUpdnUig7Z9jS5DXZSwUUsI APNUSayjxtKTJQLbGlDp+9Fsu2k6bewkBYH1kd63JcqWfgznsVVwRW8yawFp2S9HzjkGQ4XQEpCa W+NkXdwurdemBfTsZsVBs3SYXY9tNYOMAHIqcCyFq7wQ9uxklIQcQNrcz5A6ahCy/VrSD6dfyft0 06q4eM9mTFsdzAxbySrIXRCwxMrq0GRGmXh+2nlv5dSbRR2OxxcGtEbKh2NhvZTAepbQlbLAaSF4 M1JQHHKYHW8Z0lbNRcYXk5H7dl+U6tp0fTRbTo+Q9RhYbG5GPth5NLvMzQ6iMeIC/0bumJ6ty8Pf 7t8sctHKu/Z4F57+r2FdVbSqi+DzaxWMKTfx4zVqXPvigjYNJqwJbLbkqH/jQ7mBTdx5NK8p7wxA 3tpvUBJzHsUFBSjKyUTOrh+QNaonigkqm4Z9/OvRxLMRTaDSDEVd2iB9wii4c7OAEgJEq6TZCJDM VBSv/xq5PVqbyTMuE1jR/yQINfDv9G/IcxnEkcmTxw9F3tzJyH+nP0q6tiLI6fPRZGuKpKXty2Rl XpPmMbdLI6SM8EfB8slwHF8H+/mtsMdsJHDXwaOF/5T0Pzsc7op0+tcEotXKgJB1cdphJ/vb7VZa AxvraAesmgFmYdBYAYerjPFjuXkY4qJr4+R5rvIiuAjiikPbcenDt5HdrRkB7H34oNETa+eGxofV SIjXreEngetlRi87ujvRJQp4FaXsfBa6DyU8JndAIPKX0GVIz0Z4cjaWHovAqB92InD+92j32TKM XRqMBduO48DxMyjcvxv5cz5FGnVWYfxsTX/U5CY9ZfMGsoaRNcrATl7h3wBZgW94Yob3WRI5fmyf kKAPlFjcZ33/o8Hrq6RA+1MXwZdj+pmH77799Yfuvr3l5m7tV2f087MIkIqIbezZmX7NcWZAVxz7 eBwivv4CZ+d+jJRxfVDUvblhSxvNtBjTQiDmknWyPh6DstCTWuqXARgpTlFzcQEKg39AXNcWsFOZ 5tUdDeuQRRVMKfCp4G8VK+Yh/XQYTkYl4WDoeRQkpyJ78SwUDgkk03rHhG0MdHL86+LSyI4oWD0Z 7phdjNL3m6U9XMk7+F3LOGmRsW1m1QrbOYI3ci/K1i9H3ucMBPsHIK1bc1ygTxgXUB/x3RojpW9b ZIzuiYIpY1G8ZgnKjx+EKyMT7qJSM0/X7XaThQlgAllPw1BCd2fbSuRMfR/53drRl6bfSh2UMwAr Z5l2MxJA8JpXdLz+qPcVH7kOYkj68gRa6ZDuKP5hFSIjY9H50xW4tfsnuKXvZDw5Yg4avbcQbT9a ipcGfooWb3+K1TsPIf7sWeSdPIL4uVOQ9t5w5Ac0oz9Ptm9NAiCQNc/BBKiGRF43dXJ0boL0QZ0z zwzs0ntKt243Lh40SHNQ/qOB+0sugoa+lBhdObuNi/DQLbfUWzti8KSNI4bMjejZ6XQuI3s9OnUQ YHkKruZ8grSQEzhzPhETV2zB+kNhSAkNQ/b8z3Gxa3Pk92uP0h6tkNm3PS4M8kc2fUqPtcw7MVsT YyxFZIqtyBjbH6UCKH1Dd4fmZFtehx1DZs7h9zoyu7RC0cbvsXHXcTT9+BvcPWA23lsVjHMHd6Jo 6jsoJFuV0cfM79MGpYsnwn7qB8OoTroFrnMb+H0zXHQPvEuu7OD3HWYhzqL5HyJ/YAeey2vRpbBr 8jbvTZNrvPMnCDDWy0Xw2elHlgZokvjrSAtsjEt9OyFvwTTYokLgKswmOzOI8hDIWhpWIyQFuSg+ tAvJ741Ann9LBpYK5ipBK/ZT8GoCKVoJ82SNVkZ+POugUZnid3ohe80qhDAAHjF9OSZ+tx2nL5DV GaRpkWWb0wmL1YXMc+eQEXYKOUnJCDufgplrD+LkuYvI3rwBhSSU8k4MlFmuXmMy834JWvM0U/dH Bs7hZ0KPNp8emDDysSMfjhZhyQILG/9xm0Ar8bkIPrbVxBmNImhlkUcpz91cs2aDWjfc0HzLm023 JXdqVlxOn6mECs5gI+Yu/QpxYZH46IcDuG/AFNTq9TmajfsCR8KjkRsfg5SIUCRn5yKSvuwlMlR5 ThosZYX0G2l+6SO4yU6WyBDkTn6PDduU/i+VKRehjfxAKpidxOmnUQUCpUsLFAVvxHe7juHFd7/E TYNnY8TybTh96BAuff4ekvu1Q/FnI+E68DVcUZthj9XCdNvhukCQUpwxm7wLQ8fuhBYC1RrBCPkG BR8NRFFP+qWdCSoC30nAaPaYszWvr9lWJtj7y0uOGsIyDW+AQJPuR/cnoBUyxgxD1opFDO6S2Rkt 9NmdZiTA6XDBnp6BDPnuA/zMy6AayzajIf4Ea7sXDcuaObjsHN6hLT0Vq2eCrsJBfsj5fDxyvl+J VEr8jInI2b0errJc+rtkeK0MnpiElLCTOHb8BD7ddBQ395mLwNlbEHXyNNtoIbK7tON9NWWHUWDm jQcEYAW3VjK+5gYn9m0Xd/ztXqOGBbwuV1Fk9h/Jur/EtgrIfGyrFWieeuGxxxpN7N1l+PtdO40O 69UppiCwhcdGk5PbswPSJo1HVnIKxn63GzUGTse1fafhvv6fYV1YLLIsNkQXFOHT7UdwK/dV6z0D t/SbgQkbjiAyI9dM7gajZM2TzaOpLxjUAXYCRyMFFg0rUaE5ZIc0+sQZHVsir21jpPZqg7ydGzBn 816WOQX3DVuC8av2Ii46BrboI7CGbYCNbOpI9K4IhtgNFH6P2wlbzE44tf4yXQSPAEwm1npNtgPL kPOWPwrJ6nb54XRt5I+K4Z0Mspz+bQgwsr+GvDSUxWOMf6rgh+xpZYNbyNQOvVPWnma5fUtc6tMZ 1r3r4M5IJKh4j3SNXXqbgoFcyeZvkPFWN+STzc3rSgSpAiWvL6ox5td43Vcrh/lUH3Zk6kIuUAWD tzL/NxiYNkTB52NRFnGUnYN6NEGjBTYSwunES/hg3Unc1m0Gusz4HmdPniRw5yK7c6tKdlXdK4Uk oYcTLlo3R8fGyOjWsji6f7svz84MejRq3tS7/1PfoPgltr08eYaitVOe61K/rv+Cgb2nzu7bY9b5 3u2T87u2RH739rg0KQjOtCzM3HgSL45fhWq9ZuOewV9i9KKtSMsrRakHmBp8CncOnoVqfabiqn7z cW2fL/D6J99h+f5wMgVb0+qEbfcB5I0bg+JOLYy/nNv2VcQzqi6aNREO+sGO1DQz8lB68BAip32C 9LMRGPfNHlzXbSpuG7AMY5bvxjkyuy0tjKANRvm59XCe1xJ4++HU2tVkXWc0AX1+A9wXBN5g2OJ3 w5pwCCWRwTgzbRhSejZFEQEhfzCJ/noUmSmJUshOU8EI3S5mNaaVLgwBfnnuAzuwgOcIbARrIN0I 7ne1qQtnq5fp99ONmj4eFlocJ335Co8LVo8F7rICZP6wApf0BIxAMvM0/PVki75tW7oMDNI0hOZ7 Auh9xMwglz6vnvrZycilrNeFXp2QOH8KkJ9Hl0SqdKLC7cLRi5not2QXbu32OfrNXo9oMnDJouko YefydHiZdVYQyA6jTkh3RJOCzPtw/CztWt9zqWfD9bt6Nmm6p0ezV1s+/LBw8R/Fuj62FXD/qm97 zTXXvFKjRo1G9Z56onPKvGmpscO7uc4P7YyUpfORnpiCecEheGLkYlzfazruHTwD/tO+QRYj7BL6 r9voKrSfsQFX9/sCfxq8CH8etAjX9puL50bOw+wNe0kSdnjKy5AyaxKy+/ihyI8+cOeOuDBuJMpP HMS52It49+tteHXUNJb7Nd6jb3cxNx8Z5Q58uv4EanadgQeHrMS8nRFITouF9dJxWON3wpIg2Y6y C7tQnrwf1qR93pXxEnajPOkgsrNicSouHpuOnMa2nfuRvH0DMkb2YyA3BBeWLMbxvQexaO02LF29 DbHrNiMvaCzZsS4DRjYw2c87d0HzIHwAJvO2IahbK+DxDseZuRLtX0Uhj8uYMBL5h9mBHOUod5B9 6fd6SgpQsuUHZPQLZFTfCBb6uk7D6DyPgNIr8Hpt3t2BboPYmObdQZelhOVnMkC9NKQzEt4fjsTF 85AbFUnWVWDoMXFucHQymkz5Hjf2mYV3lu9F/LGTKPpispkHYqdbImvinUtCVuf1LLQUaV38kP/B Wyic8q4nfdoHoVFffTFg1aCAexcEBV2nlKj/SXMZBFqJTIF6laJI36Rwn2/77PXXX1/vwQcfbNWt Q+tB+z4dm5O8/Xv3hchIfHvgNFpNWoVbBkzHNb1n4b6hMzH222Cczc6H3W2nX2dHbmkZlu8Lx3Oj l+CGAV/iz30X4Lre09D9yy04kpgOm6UC1ouJyF23ErlL5iLvu6+Re+QoLlzMwqSNh/HsyIW4vt9s XDVoLq4dOBvX9/wM4zcdw8qT5zFg6RZc32cy7hwyF9+FxiMjNRrW1HBYM86iouQSMopLcCQmCdtP hONMfBx96kyUpoeiOCMBn6/egUeGzsZ1vT7DXXRh+nw4A5tnT0bIlq34dOlW3Nr7c1zTZwbu7B6E pWt24OLSeexYLWEjmBwdvX6hHg+bx8gadyUDG+alK2OCSYJN5t37Dtnr7JBNkfHeUOQd2GncBjOC YrfAmpmMgj1bkT6yL3K7vknwktV5vHmBVEEgr2HTfAaC1cbAKndgV6R8NZ1BWBj2ngrF4l1H8PWh UISmpsNqHty4Ue7y4PuwRDw2ZhnbZQ4+WHMQcYf2onD2eDPu7X13TyMLr6GkCwOy8QwYN25E2oU8 rD4S6Zm+6Yh76a5TpSdjktclXLrUYNy0adcHBQVdXSWX7791q8q2vnFb3yQarQCmdeCe0Oqv1113 XUP6OQGzF8z+7PyF2PxF+0LcraeuxW2DF+Da3vPItDPQYMISzN17EhfycmAty4MtKwGW9FhYci6g oKQQs/ZG4P6RX+K6wfPxwrtfYPnhcBSTdQoqynGOQJ+9+TgmrjlO838UPeZux/MjF+CG3pNQneC5 uv8XuGIg2br/l7iSHaTORysxdPl2dJy1Bjf1noInh36OkNQcFGnoqaQEh2JTMebrYLzKMl4cMhkf LPkBoefPoaKAdbl4FGXZF9F7yjLcQtelOhnp4eHz8O3+SGydMxV71q3H2GXbUH0grzv4CzzD37Zv PoLUr75EBl0BvVau2Vga/zTzXjUngcD1vkIu9vWysXlgQpDo8a+V7oeNn/mBDRA3ui9KTp+CvaQU FwtLsT4kCkuDDyIn5gzS5gahuE9rVPi9gbIeHVDw4TiUzJ6GwgWTkTumF9LJsKlzpyHlUja6zd+E u4bMZMzAe+g3DU+PmYcjSZnIKSlHAYPAOXtPo0b3aajVfxHm7IhA9LYNSP5sLJJ7tUJW7zZI7h+I 5NHDkLnsKySEnMHaE9F49r0vUX3ALFzZdy5u7DsT9cbOS/rw680Thw9//6ZRo0ZdQ+DKKgsz/9bN B9yqbPujR7s1a9Z89sYbb6z36KOPthww5r1x87fvP9Nk/Ff2+wZ9iRq95+NOsmDTScsxe08YorOz UVCUjuLkEBSf3YniM8Eojj0KS8ElHDgbj/5fBpMtZ6Jm908xc3cIzmUWICmvBF+Sje8cMAm1ek3C g2Tsl8ctwpuTvsWQr/Zg0akkfLbjDOq9txx39ZqCWj0m4ZFBn2PynrMY/t0hPEef+g6ybfvPFiCx uAxR2eV479ujBOJC1Ow3B88Mm4t1p6KQnZ0ER1YU3YSjsCUcgT3qAI4dO4jhX3yL196ZhSd7B2F4 0FzsnDsfMSuWYveqVRizYDleGTsTz/cNwg/f7kLOV4tR0quDyePlfepF0CrIoZjRBQY4mllm17hr pR+qecF6+FFAIKZ1b4XU94chd/P3yEvPxMLdJ9GS1urOAVPw8nvzEXw0BEUbvkXe8B7IHBiIwm+X I+1iKpZuO4SDZ6ORtHc70lYvxfl1G7D6aDzue2sxqg2Yj2psi2rs1DUGLcDARRtxJiUTpxlzjPxu nyGU+wbNx+aIVMScOI6cyDAUX0hCclIaYhNSEBqfjh9OxqPr3E108WbhWpZ3ZT8SxICvKAtw17C5 JW9+uGDz6A9n3rNw4Xc3Bi1e/G8f160KWrGtfFvfUzKx7f1XXXXVk/RtXyJ4G9Z7443OrQcM//Kl weM99/QIwotvL8KwxTuw7XQsikoL4chPQ1n8KZSc34uSmD0ou3gCFYXJyCgtwewdp9Dww1UE3Wzc TwabsP4w4gnYfJsTiw+cw0NvLcJ1A2di2MqtOJaUjKLyEljI0NZiMnfhBdhthSitKEZKQRkiLhXj fF45IovLEfjlRlzfdyqeHb8M3xyPQEROMbrNphUYOA9XsVM9NHIJtp0jA+WnoiztKKyJ2+E5txWO bYuRNa43Ekb0wMUpE5G5Zg2ytm9noLQaiW8NRHLgm8gY0AmZU8chc/0qFISeQvHab1BAX7KU7KrM MWbck36tmTyu0QD6tpqwonfqrDTBxX5NkBPYEsl9/JHz8Sjkr/gCJeGhiE3MwOydoXjp/bm4fdBk 3ERWr97vc7z48SKcioxD1tIluDisP7K/mI6ww4cxYulG3NL3c7z56RLs3XMIBceOIGLjVizbG4kH hy+gKzMH1fovwJWUWkMXYBhdnPNZBfjmRCRe/2wlag6Yjebvf4mzmbnIpnuy6lA4WnzwJe7sMhG3 9/wYN/T4ADf2/BCPDZ2Khu8vwRN0nW6k/q5gcH3loHm4Z/jcotbvL9jQ872p944KmlWrd+/L0x7/ Laz7Sy6CQHt53Jagfezaa6997o47bqk/cli/PscP7liTm5tWcKGojAqwotRSBntxJhyXomA/dwAV 4cGw6PPiGeTkZeFkchY+3ngEj5JBa5Blb6F5b/DBUpqs48i0O5HtdGPd6UQ0+ew73ED/tc6EFQhN zkBxVhIsSaGwxB6GNWYfbOe3wha7FRXxe1GaRAClJaCYPvFHa4JRe8wCMydi6IrtuFBYbsp+6v2l dCvmGb/u2dFf4UJZOQovhsNyah0qvp+Cggl9zTTL4lYvmsfCSqjs9mvGz8Ymqve+Eq5giKxJUOrN BIve5FXSEg1bEbjONnVp+l9DmZ8m07REUQ8/+r7dkDyoBy69OxQpn49H5spFyA85jvS0dIQkpGHZ oTPoMv07PESTfitN+20DJuOtb7dj/OYDaDVtFep8uBhhMclI3L4T8V+vQMLhE1i85wweHfUVbhi4 AE+O/gKrDp5GUlQMTu8/hPiCUvRbvhMPjFjMQJfu14B5eGrETOw5l4KzWYV455s9uG/YbNSdsBzb o1JwyWLH1J1H8FrQV7iLnaXuB8sRtOkEVoXF42hmIRJtLmS7gAybGzODj+GNoEXoPGu1c9iCDSe2 RVzoezA2f3jwqYQnnnzySbkKws3/KHCrAlZMW3UUQcNft1599dX33nTT9Y+98Mwzrw7o5tf+xNZV 32ac3JJeHLHdUxoRjNIzu1FyhoA6y+iY7oAjagds0XtRlnAcxfmXsCvyPLrO+YHKmYkbe0/HPf1m ouecjZizPRSpBRUoYUBysbgCU3edwGt0MW7q/zkafLgU++PSkJcWi4qEQ7CeD4YjRg8FdsIduw32 6E2oiN0Oy6WTyM9LwabIGLw0bjoeHvApPlm7HylFJcijnzxh7QE89t5KVDejFl/g7uGL6GaEICkj E/HbNyAy6F1cGNoHWX39kUkf71KPlsjo3gI5jM7zApsbyenWAln0AdPpZ17q2xYX+7ZH0qBAJI3o g6RxBGXQWGTO+oTAnIusDQwi92xDXkgIMhkAxiVlY/upREzdfAIjV+1G3fFybybj5q6f4layau1R 89Fl5lrMJ+Mm5JWhlJ33eHwqBn65Gbf1nYHGn67AexsPsM4nEDBjDR4cPB21+kzCM+8twC1k5+c/ WIzBy/djJl2niZuPosHEJbhn4Czc3Wca3py4HCuPR+KS04WgNbvwysg5aMTjl9DPTSuzYXXIOTz3 /jzU6vspei7cjPB0WjSH00wSsjOAtrjdsHo83klEDPDsGrJzuyz5xcVrjhw5Um/Xrl2P0b+t+RPg /svdhV8CrFhW47U3KNWnsn43bdrwidatm7+4edXCd9Ii9p3OO7OjtDxyq8dxdiucZwig8O2whe/i 9z1wnyGoIoNhp5Sf3wdHThziEuPx4Zcr8dqQjzFq2SbsJIOkarZ+eQEstgokErhfHorDM2TJm/uT hQdMQ9NPliE4jL5naQ7sF47BGc/OECeW1dOuLXDHbzfjr5aEvaigj5p06QK6fjQNfResxoaw8wzE ClFRlssArxQbz19E7fcWkW2noVofBoz95efOQn2y+Yzt4QhPzEFORh4KUzNQlpKK0otJKE6IQ1Fs NIpjzqMk+izdnCiUJMbST09CQWoKcsmY2Vk5SM4uQFhyHjaFX8Ss4FN4a9l2dJr1Hep/8hUeHzMb tw+k/91zGqp3nYXqveaiZv85tAYEz4fzMXPnCeyNoy5KyrzgcMNke2JcijKrB/uiL6L/ojU8/13c MXAy7uwzGU8OmoouM1ZjU1QirUYZxm/cTd9/Nh7uPxkP9f4MD/f5BM/QvL9D1t0aeRGXym3Isdux MZzMPnE63l2xDgcS03Gx3In10Rl4he7UTf1nodXMzdhynm6dywmrZrZ59A6fwOryPpp2W+F0VhDQ Du5zw+JwJmbnFX45YsSIWwICAq5r2dIkE/kfAe5fBez1119/0yN3331X7UceefDR++57/OzBHdMv nTpwqvDMIXt55D4GMDvIqlvgjKRfGLkd9jM74IjYCc/pYCB8MxCxCZ6Izfx9B92Eg3Cknoc9JwXW ggxYyYw5CaEoyYpGoaUIK46Eo/74r1Cz13TcwqCpwfvLMW3zKWTkF8GVz3NiDpBZd1GCYYthJyFo veJlX+t5XiORgRWPdUihZBanEmpIwR43GcKDcgLi4IU09PpiDW5joHc9AVRt4EL6f3NxLSPkGr2n 4KZen+HOflPJSAtQb9QiPDyIYHhrDh4nQz3z9lw8R5N854CpuH3AdNw6YCb9ULJU7xn0Bafhhp4z cH2f2bi2D8vrz+ibZVcnQK/vOQk3dRuPR3p9gH5zvsOasBhEFZQggy5RGUDm0hRJB9xOMhxZrpSI 3RV3CW0+/AKD5v+ALZFJyHR6EEXLkW6xItfqRGa5neDiPfK+PCAbshyL24MCArSYZj+P8UER/67g r97OQGH5hZZS7ncii3/voBXrPm8D2X4KriPzv/reV1iwNwzZNk3HtHt7jyaks35unqNH7y63BXBS HBZ4NF3TWW6zWEujt2zZ8tjy5fO0tMG/lHH/JsNS9HBBiejufb1u3afXLv2id17EweTy8N0OWxiB cnoX2XQf3OHbCNAtBOpWuCPIfGeCDfN6IgnayA1GPJGbCNztsEbthJWfFroPFefIjmTh4vijKCvN xvQftuCVwR/h5SGf4KOVwYjPLUZxaQXKC7JhTQlDhR7BxgTDHb0b7nN74InaBZzbwUBqO1zR/I2A duuYpAOw5saAaodLzUnACrR0y2CzsYHFZGSPYgI6PD0Hn289hAcHfoTqPShk+OqMkqv1YUAzgH5h HzIzv1/ZbwH+NGAh/sxIulrPhUau6kWw92Zw0ucLXNV3Nqr1mkZwTkaNLh/hls4f4Am6KC0+XoK3 l+/B/oQsRDPQTCm2oNDhRhk7lF6bt7vIXGQwQgOayWsjUGxktXKCJCwlDXXfmYQaGm7rPgG95q1G HOtr52/KqedWvjHey2XhPYHg5C0b0VeVK0BTA7yOi+e5yOC6rgfh2RYMWbELDwyehpt7T6Y7MQW9 F27E0YR0lFotcDnLeXYJRQyr5H4WuCsyYc+jtUk4CHvCUTgSTsDKmKLkUjiK0s+6SrOjzxRmRr57 Ie5kbWJHmPrdgasCfaAVYH3DXAJsrXvuuefOFi1aPNaqSZPaaxbN73N298bFpWf2WZ2Rezyu02TY MAI0dCtcYVsI2k3A6Y1wnyarntlKt4AAPbudfi2Fny4J97nPeD89Udu4L5iyEy4C2RG9B7bMaOQU ZiOvtAAlSviWm4DyC+H0WY+RWfeSUXmcWDWaHYLgBYGKc5Qofmd5EHjPs7zY3bDH7+G5h+Es1HN/ MrUG28W2BIRMnYM22MFGF/uKhcrZwPn8+2KZBdE09REpWTiRlEGznYH1DFi+CY3HiuNxWH5Mn/H4 JiSeAeMFBEel4UBsJo4lZSI0NRvneG5CYSlSyq3IJosWs+xiAqqC4iBQ9E6ch6ZXcHKSueyyAprp RkB51M2c3pxh2mejJOYW4O1FG/HQ0Lmo0Xk8hn21ATllPF4vQ1JUlCaxC6De/4kZfWgVA3vLpRII XAKW+yw8Ib3UgpUHz+JlBmX3EbBvTFiKjzccwvaYVGST6S10DQRaj72IpJoNW14i4wYGwslHYLlI i5lE4kjYBU/8NrpotHbxW1FOnRclHvLkJx+3FGZGrEpLPvk6cSTgCl+/C3CrsqxvzoEv8NIQlwKv e+666+ZHgj4c2zz+0JaVRaf3pVvO7Hc5wvfBGb4XrtP0XeUKEIgeghUUTwT9TIrLyGaClO4BWVaC yI2VIvZdR+Dyd+MPe31iN10NBW8OsqfdCAFKINoitxH42+iGEJQEuPM8Az26CJ7zm8i6G8wbCe5o dpzzXnET1O7oHUac/O5M3Akb2deRGQlXcTJc9hyyTglBTMYhg9jIPmIg+hGiL7KKphbazGQe5WNw kQnt9OXsNIsO/iYzqxx0DmKDHMTfyWQ8xu1xEEB2A0DNsXUZ4e8EkUMzvXx+oTmWzMeyxPhuAsn7 BoWvDO/TLDcvoBliFdyfTXfhbEY+IlIzcYkWyCWLQbqVK2GY1wtXIZVCsy7A8quAyjvkXtWLleZB HnZYp9OBMsYRO+j3H4/PwNm0fGSVlsNmt8BenAdHRQYseWdgS2MckUyQJmiSEduc1sxJ4nAylnBr shH/Bv8GQSsAOxL3uSsunMhLPn9k3JH9G1+Qn0ssCV8+d+Ef3nyArcqyPrfAPEyoVavW3S+++PTj gR1b1lk07ePu6cd3nK4I3VXhDCWThbHiYQQPgy53OJmOAZjxX8MJRgLXHSE3wSdeEHsITM8Zgoq+ rxGCFVESsibZ2E1ASvTdw/1e4XnnfiJiWQFWEsNj6dt6YnidSvH+7RVIeDwEaAZunjj63gm0AIm7 yBgHYc0Ig7MgHp7STDqVhUQgvT8xHsElYImhTGObBhcQKsWAW4igCCNGBBICXuebMvi3hIDln+a7 fEKBUuXq0yfmWr7zTDeo3GfO57m6HL+LUYlPXt5bLg81dRAW+UHxgt9blrdMtzqKOiHZ28MOpe9m DrPxV+mXusimjlK4yrLgyE+CLeMMrBeO0vTTslFPNurLkUBrSvFQ3HHUbQKJKpGElUDyiCMe4uiy JZBk4imJB20lsYePxx3bNXh2UNCDgwYNurlZs2bCVVXg/sOs6wOsz5etyrJmTPbhe+99srtf+zc2 LZ3zQX7k3oKK0ztdrnD6kKEEWCgrGkY2I4A9BLCHroInnDclF0EM+yPgesUjP5cCugdG6B54TTsB +CNhWed4rBGeVxW05/m3cQ9+m7jJAu5Y1lOKpcJdNGXOhM1wJfEziYFj4g42zB445EqkhMCRHQNn aQY8NoJYjar5hGxs0jM/vcmYlSdX+0yuXAHYi1mvEEC+738BdBXh/37rP7N50cjrS8SUvJ58AqHX IFrfJaoLO4Vhcy949U/ugTlGdWaH89CH9tDsu2wlsJdkwpIdC0saXbCkI9TDXjjiSUjxJCSC0QDS TN2kztnp3bEb6Z5pMj3bJ3E3haRlRm82mREda8J+T0Hs/uiQPd+NWzZvcqMNX89/bcHnnz/crXVr DZnKkv9TrsIvuQa+4MskVKY8cOONNz7VrFGjhod/WDG9MHxvVgX9V0cozf4pAjNkI8FLdiVYwaAM AnA4zcZpmggyqovM+p8BXLoU9IXl40ocGjKTohMI2jg2QNx6MgddF72GQ8W7YiU8hz6bjWxiFZjT I+AiC7kZLKKiiKzMeJ9BnMBiWFlSxb34i1T+Vine3/VdLogY8cdiAMdyjOh7pXhZU51Fn14GNSxa +alz5YroRUyNDjicdgrdGnuZ8edhyaVblApHbhycZFJn8gn6pIdgi99L2WUY0pFAV4ys6pbI1NMq yTppHjJi2V7UiYcdXxPnnWRVD8W4BAIspSJuhy0/9uDFo9u/mzTp/Xea16hR44GbbrrpzjvuuEN4 EhmKFEWO/1RwVhW0PtfgcqrPm2+++dFOrZq91rV9+xYnN6xeUnxyT7rjFCtLYLpP0YcMoZ8aKuGN EchGGJB56CY4ybT2MwrI5Br8JwCXYhh3J9nWy7ouBRBiEDIvKAKsHlboOI8eXMTtJnjpx0kEdplL 08h7YUnYD9vFI3AxMPFknYE7LwauomQ4aGKd5dn0MrJJ0jlwEywem1dQRTy2PIKp0ADK/TMp/pG4 zL4CuMuz4C5LN+IqTKIkUhLgKIyHoyCOQWs0LFlnUZYRCUvqKfrxB3gfZEK9oaEA1vdARr6pLEv8 brKjWHWXAaI7gfqQJFJPBK78UxjgahK9hG1JvZl5yXE8n8GuI46uVvwWT0XCDktaxLZT+9Yvn/j8 80+/9MILtWvfe++9ms6qF2RluX8JtH83cH/KtAKt73HtrRST6vPppx97qVat6+uEbfr+24KTuzPt oXQFQngzIWzgMAZPdAcknjABlzcWQp82dD3BS/Y6vR6uiL/uKlwGbBXxyKet9G29/i2BzGAM533g /eeAi2heVxKjxuAnmUKA9X7yGJk9mkM32Vii79r/l+N8wr/paigA8dD18MQKHAQ5QeAQaxkRo3vF SR/wx0KwUOwEke0XRC9hOugvVhWd5+B1nXqT+LLob7k8AhqBV1lvb93FhNSr6klwXRbtM8K68xif 6BzVX53a6KYSrMYtIHhdPMdNV8qT6GViPdCxxe125Z3bnR6299tvZ342rt8zzzzx6iuvPPds/fr1 n6SV1ntmIkBhStj6JdD+XduvgpbyyJVXXvnMC88+1WjjollTcg9vvVRxiiZE7oAeHNBVcIZ7n4I5 KR6C2AA3lMAlaBEu4XczFPbLjPvvAK6bDeIWa1QGZqB/C7oKRgwg+fdlYd0lcRsp/Jsg8TY+G5bg crORxV7GZBIE3oia9TRA/ouALAeync75sYj1vYwvX/uysF4eAuOy+IIgMqBTbFd5rari4m9eIYjp 6kjEnN5Oxzr/FuG9ydKY0QDjEkh4bVkhluOg3uRa2elKVMRtdyWHrD+9Zun0D+u98kKjpx599OW6 L730/ItPP/04saMZgcKRfFmxrIZR5YL+08HYT0Hrcw8ug1ZM27xxw2aTRr01uODEzhLbKSr4tBek jhA2OkHqDN8CO/1YL3B5k5Vjtu7TFD1wMPuoEJ73nwVc+a4CCf9mQ5jhG4oYSA1oTKQxmTyW4gOC gFH1WL1fJn/P18BGeI2/CH/ziTnup8JyTEfgsQZgEpahT8OSlVLlNwHZVy+veOt7WVgvr4hBxcK8 bx73lzJ+KlV+q3QJ1KHFrl5rIcsgxt9DsO5xlyYcLtz9/YK5o4b07HbDDTe8fMsttzz33FNPPcvv ep9QiV6EIbkFipEEWOFLOPMFYv8QaH1MK1FhvkDM59OaubOszLPPPffc6/OCPhydemB7lDUk2OVR oEU/1hFCtiLTusMYzBCgchNcGkEwIOV+AtZ1mvsEVgZpoGuB02QeA96qwuMj2XCV4pHQx60K2r8O 3L+A1y3gVoKyqmjIy/v9p7/rb68Y8JD1PMa0KiKmqad4G0oiky6/j9cXI6mRDTtXsjEDOsTxU4GL ylP5LNNFMEr0yrqHwJN4z9engFJVtF/l/0apZHsfY3v3q4yfCq/LTx+gfZ3uL8z8c3ES5A6f8Fy9 tlQWt9cWc2TtoTFv9e3/xBOPNKX5r/vA3Xe/fBcxQqwoP4ZyGiuAF35+yrA+t8AH2H94E3BViApT wbqAxmh9aZEeonvw9ORRw7utmTP1w/Bvl6xxndwBm/xYgtMdQkWF0HcK1ZMxmiSKhy6DRD6vEX3X foLbRbAbAFMEXJ9on4vAdZ8hIxCw7rMMGPSUrFKcBLCTgHUyKHPpKdo5lkHxCLyV4j5PkBvR36xD NIFsHjbweyUL64GDF6w8xgiB4zOBhukkLIMN6m1Ub5TsoNgT6WfSn3MStF6GrQqKXxYdZyb3JO5l GQrk2BHoq3p9T5Wj43zgZV0vuwSsI8FyOTD6a8Lz/+K/VvqwrP9fwFulY8it0SfZ1rgZ/O6iOPld Y7BGZEWSuC+RhJSwCRXx2zx50cHFiSc3nD0WvGLN1I9Gvd2y8Wtt69d5qWmndi2aEh96TKsXXvVG iyyzhkn12L+qD+tzCf7h4Ounm49tBVzfOK1vvoHv9ZonH3vooXr33ntX411L5i8sOr6r0BUSTD+W 7kAYGzeUvVzgDaWiGYx5NHpA39bDv80+s79SxMo6jyB1koElLrkIZ6h8w7BkOrkGerpmRhd83yUs M5LH6qkYwevQk7JoAsrMNyC4Ke7zZPLzbDyC1y0gK7cBxXw3f3N/5VMyjz5jeA59TePDVTXDRtjo Ep/5NsdIKvdXAvO3icqrBE5V8QHK+NFe0OrahukY7PjEy34/ASzF5+96fXIJzyf4vGD1ia5P3cqK VIpcBnU+J3+/LPzbTmtiZceqSNrvyo0KTo7at3LvD4s+mdqvW6eeDeu9+GZgYPu2j9x//6uKc4gL gVWjA3p3UFjxsavwI4vtC7qqugTC2z8FWG1VQevza9VDdPHLKezvvv32l1fP+GzcNzM/C7oQvPaU PWSX204Q2sm2jjA2PAWhVIweOIiBq4iLwHaGE1iarhhOBtVwmdwIAtZ+ejcsEftgOXMAlshDsEYd 9lgo1uijrvLzR2wl5w5VFEUdKCuKOlhWGn2ooiLmgMMavd9ji94H+/k9sEeRuaJ4/XO7CFSBlQ1C wLoITonTPMLlNc3fBPB5NrREjOtjXcPArCuDJa//x4Y18lO2ErAqgzIjcgt8oPg1qSzDgLKKmDK9 4PKOWki8TO4NvEgAl6WSIY0ItKwz5eeM7C3H97uRy2V7xcn7s5GZrXSDrLQAloT9nqKYPcVJR9dG ntqydPOWr2d/MaBHQJ+mjeq1Y9s3vOKKK1659tprn7/llprPEoVVmdUHVp/v6gNrVXb1uQP/NFir biqsqougC/80l1dtVrzOn//850aHVy9ZU3RkW56LALUbN0GuASNogVdPyIyrQB8wdA9s9GHtetx7 mqCNoJnkpyViB8rO7LGnH9ucemb7ymOh274/tGr+tIUT3nkrqE2zJsOeefyRXi89+3Tfl5+t3eeF 2k/2qf3kY32efPyR3k8+9kifp594rN9zzzzR/4VnnxxU+/HHB774zNNDBnTtOP7beZ+t2LFs5qaQ DUsOpx7bmERwuy0EtkMzwciQJvIlg2kM1kmguugamKdkZEyPImONIihph74bJpJPy05AM+6pHOLx AofHJWzk3xu8ogcSvxm4fwGN16z/5W+B1Bs0Uch4Eu2Hyk9Yx+us4z5eL34Dj9lI1mX8wLo4WCeJ nUCWD+oFrKyBr+PxXrjP66OyE8u9ocjNKYjanBe9f+WJfWvmfb9+6Yz5LZs36P7www+0rVGjRtOr r766AaWuXqnSGyps/ycqcaCEhIp1RGhyIX3M+lNXQFIVrL8rYLVVZVufiyAH+kcuwl233lpncK8u XTs1b9Lt0v6NSTa6CG4GYg6N1Z4iGAhYF0HpOk0Ai1UJXFsIhZ+W03tceSe2lZ7dtjI8/tAPMdM+ GvVx3Vde7Hr99de3obSuWfP61lROq2rVqjVnx2jO68lf8kmzStH+FpSWlFaU1pQ2PL49peN1110X QLMV+Kc//akzFd7t0QceGPDe24M+2/ntl1sTj22IzTsbXFgSvctSFrPDYY3d4bHR7DsYMDljNhPE m+gmUMyYJNnPBGVi2kogEdx/YS6CPtFrwr0g+TEwf010vMZUvUNW1JnKprjYoVzqWBR1Mh8DK++Y dxzWe01XJah9n+ZBgOlYYmeCVMfyHJbrccTucFqid1jKY3eXF8bsy00O2xYVvve7ncd2rF4zecKo Ma++9HwngVR5LGrWvK4h9fkq5QWKAitlUFTKAJ8LoABLIwI+n1UYqcqsPw20fnd2/enmu4h6iI9t qw59mXwHYttnHn+4zcn1q4JLTmwrcxqflQxE1vVoKEzjtaeDybDbUR6y3VMeut1VGLIj51zwtwd2 rpq/dPyoIW9Xr169GUH2BoGlKWuvUepQpKyXKS9WihT3U/H9puNeoei8epT6FJXViCKQC9wCdZur rrqqw5133tmF1+xMQHfmZ3ey9sCxI/pOWrts+g+hO74OuXhyXWp+xNbC8nNbK+wx29wuAlmM7GVi gaCStRRA6cmRni6ZsVkNwvuEv4u1DeB+XQzja7iN3w1oCV6vS6DreL97mVeA1vGqk1cEbk3N1AMI C69dEbfHVRa7u6Lw/K78vLO7stlBzx/dvGTnru+/WLf923krvpoV9NkbDep0v+3mm9uIFO64444W DzzwQDMfm1JPL1Gepyio8jGqgCrXUMG4gqufsqpvCOunPqsPqP8Sdv2lTRfUhVUJ9R5VTr7KZbal vHD11VfUb9349S6pe9efrzixxaKhL2cI/buTZAYyr/3UerLrFhSEBOed3fHDnrmfvPf+a3Web/vI Iw80ffappxrVrl27AcuRyZEz/xRFA9HqFMo6rjE+KUzXkymS4nyiv7Vfv+s4Ha/zdL7qJqWLIQRs gVoN4gN0E8plMFPaseN0uvGGGwIpXW+qWbP7gw/e3de/Q4vRQaMHfT7ro5Fzj21cujszYmdawbm9 hcXn95aWxuy1W+L3uq1xmqereQya0ST/kExIUSTufUjgZc5fEt/wl+Y1OCkmMR4BrydjrqS9cF7Y D1vifvOIuCLxgLMkZl9ZftSuvJyzO7Kyz+9LTwoNPndo49L/r72zaYk6isK4+xapI5moIbQotMB2 IpE4VqPOqOmo48so2sJclK8JRhpoERUiROuiVYsiFAokwraRfoDAr9AmoxdbJN3f5AOn2xhamlZz 4CGY+f/vOec5zzn3KEKzd6fH7kyND9y4ebnv+r3bV6emr41OxGNnetLT08mryiHkbq7TTqRBlyv5 wzkNDi/wA/9HHBApHMInHHP1a6JKqKyKdqpKrAh123bWjRpOcU4gBPXDr78cSJTOPB46UdL8dnF+ 5cPC3JdPCzOrHxcer664qfv55ZPVd6/m3i/M3H/Y190eL8jbX7YvM7PEXUFMS0TKIs9ZiJApDkns SBDFHs31Q7MASEsGvuM5YuM93qe5IB3yETaixhc+aRD8EzsTWmKmqExn1o5qBwRd41Dn9rmom9RR J4BGN5Gac3Nz46GTwd6m+khfWzQyGI9Wr6FyMN5UOdgRqxrqikUSOBuLXOxuqxnubgknoM87Gqs8 VA6A9nqHxnB/vCnS1xmr7Z8cPT8+cal/bKS/d6ShIdxTXHy01fmPuphq6mvDneXlZa3uBklMTocK x21FIBAIuji54hGnbi5yRqA0NI0NH/CiSQpf8GanKTXXD1WaqPb6t0IFO24KhMAIVMJFTCQo4dKt kFN2a6hniD9V5LcJy26/fbP4dPn1/MzslYFz7YcOHijNytp7LCNjD+9AFkKlARCZfupkDYEkdTM+ 6Wh1tUgT9Jme4Xne42bgDOKFfESND3zRGDQI/smB4jFliIui2unMykLxtXIwpRO7tRNIKDs7O+IE U+NQm5+fX7ceCgq+Idl3HjinFhE6YYbXUJWXl1fpEHLX+SkE6VYzYiI2eKfxiJcmlDB1c5EX+ema J2d2Uk1RcQ8/Eqnl3orUXv1WqH/s+t+oWeFq4iIqOpGkuaK5kiFJk6u0PRysX3r24PnS/KMXk8MX mrtaGoOFhYXF/Nf77nu6WtfOzxZ5SPKJ2gh4Xu9yjsTN2RI0OeBXYma6JJvOxEvhEYBWDnY+7dXk zBQTEM/vQOdwLsAHvvCJGPFPHDQY01Ki1EpF3NSEHGhMhoKmJ3lSNw0HTVH4EPc+/8lEKuxq06pA 4CRDYiRK4giPQkMWxFFcCEXE/FvkplFRTk7gsJtMmqy8A3GQxjnqaJ8oS5C6ebOwZ0jQErUETT7E sN50puCa0OSKGBAF+SAQu1tvJSRAgC98MiUlRgmS2CRKTU1fmOQlrsnXTlDLezKR+pz+VWYLL/FC BgWGLDupIFlEa1fVrqTJ6ovVkrVdBFnylY/gi1nTmTiZRMQsUZMDIHft1ID8tgo6UyIE+JMYfUES I7DC3Iw4Le/gnzFbbIkXYlRUCFURLfl8Bsk8w7NWrCJQpO2k2QKqqCqyBA0QgoQtIBQLxPOr8M8C 1hewYhSXVpTiVdz6+O9M4gWQooKqeBCvzve7XwSLVJ2zW7ubuCxs3slgRbOVSOZLUEzi0UfKPIMU v5CQrM63sORbklOWsh0z290SpQ/7DEhZylKWspR9b2lpXwGGY4P5bQ8pBgAAAABJRU5ErkJggk==

بررس

تظاهرات بال

و پاراکل

ماران

بستر

مبتلا به کوو

19 در مرکز آموزش

درمان

منتخب دانشگاه علوم پزشک

قزو

مطالعه مقطع

که

فلاح

مهناز مراد

ساره محمد

دانش

ار،

گروه پرستار

مراقبتها

ژه

، دانشکده پرستار

و ماما

یی

دانشگاه علوم پزشک

قزو

ن،

قزو

ن،

ران

کارشناس ارشد پرستار

مراقبت و

ژه،

دانشگاه علوم پزشک

قزو

ن،

قزو

ن،

ران

.کارشناس ارشد پرستار

مراقبت و

یژه،

دانشگاه علوم پزشک

البرز،کرج، ا

یران

Sareh_mohammadi@

mail.com

اطلاعات مقاله

چک

ده

نوع مقاله:

پژوهش

اص

تاریخچه مقاله:

تار

در

افت

21/09/140

تار

بازنگر

20/01/1404

تار

پذ

رش

/1404

تاریخ انتشار:

/140

کلیدواژه‌ها:

کوو

19،

تظاهرات

‌

آزما

شگاه

تظاهرات بال

هدف

یماری

کو

وید

-19، بزرگ

‌

تر

ین

و شد

ید

تر

ین

یماری

همه

‌

یر

بعد از آنفولانزا

سال 1918 ، محسوب م

‌

شود.

ظهور

این

بیماری

چالش‌های

بی‌سابقه‌ای

را

برای

سلامت

عمومی

ایجاد

کرد

ین

مطالعه

با

هدف

مقایسه

ویژگی

های

بالینی

پاراکلینکی

در

بیماران

متوفی

بازمانده

از

کووید

در

مرکز

آموزشی

درمانی

بوعلی

سینای

شهر

قزوین

انجام

شد

روش پژوهش:

در

این

مطالعه توص

یفی

مقایسه

‌

مقطعی

در

مجموع

تعداد

324 ب

یمار

بستر

مبتلا به کوو

ید

19 (149

زن

و 175

مرد

)

با

استفاده

از

روش

نمونه

گیری

در

دسترس

انتخاب

وارد

مطالعه

شدند

. روش جمع

‌

آور

اطلاعات مطالعه پرونده و ثبت تطاهرات بال

ینی

و آزما

یشگاهی

بود.

داده

ها

پس

از

جمع

آوری

با

استفاده

از

آزمون

‌

های

آماری

تی

‌

تست

مستقل

رگرسیون

چند

متغییره

تجزیه

تحلیل

شدند

افته‌ها

بیماران

متوفی

نسبت

به

بازماندگان

مسن

تر

(001/0

P≤

)

دارای

بیماری

های

زمینه

ای

بیشتری

(001/0

P≤

)

بودند

از

نظر

علائم

بالینی

تب

بعد

از

بستری

(015/0

)

لرز

(004/0

)

سرفه

خشک

(001/0

P≤

)

علا

ئم

قلب

(018/0

)

ین

گروه

متوف

و بازمانده تفاوت معنادار

داشت

. افزا

یش

سطح

پروتئین واکنشی فاز حاد

(001/0

)،

سرعت

رسوب

گلبول

قرمز

(020/0

)

لاکتات

دهیدروژناز

(009/0

)،

کاهش

میانگین

سدیم

(001/0

) در ب

یماران

فوت شده نسبت به گروه بازمانده تفاوت معن

‌

دار نشان داد.

ضایعات

ریوی

با

الگوی

گراندگلاس

شایع

‌

ترین

یافته

در

اسکن

ریه

بیماران

در ب

ین

دو گروه زنده مانده و فوت شده به لحاظ آمار

تفاوت معنادار

(05/0

)

وجود

داشت

نت

جه‌گ

علائم تنفس

ی،

سرفه

خشک،

سردرد،

لرز،

یافته

های

رادیولوژیک

کانسالیدیشن،

علائم آزما

یشگاهی

کاهش لنفوس

یت

‌

ها، همچن

ین

در ب

ین

فاکتورها

دموگراف

یک

سن بالا و داشتن ب

یماری

های

زمینه

ای

تظاهرات

شایع

در

این

پژوهش

بودند؛

که به نظر م

‎

رسد با

ید

یشتر

مورد توجه مراقبان سلامت ح

ین

ارز

یابی

بال

ینی

مراجعان قرارگ

یرد

استناد: یکه فلاح ل، مرادی م، محمدی س. بررسی تظاهرات بالینی و پاراکلینیکی بیماران بستری مبتلا به کووید 19 در مرکز آموزشی درمانی منتخب دانشگاه علوم پزشکی قزوین: یک مطالعه مقطعی . مراقبت امروز. 1404

؛ 18 (1): 30-16. https//doi.org/10.22087/ca.to.2025.409245.1012

ناشر: دانشگاه علوم پزشکی لرستان

This is an open access article under the CC BY 4.0 license

https://creativecommons.org/licenses/by/4.0/)

مقدمهشیوع عفونت جدید، که در نهایت به عنوان کرونا ویروس 2019 تعریف شده است، اکنون همه کشورها را در سراسر جهان گرفتار کرده‌است ADDIN EN.CITE <EndNote><Cite><Author>Favaloro</Author><Year>2020</Year><RecNum>71</RecNum><DisplayText>(1)</DisplayText><record><rec-number>71</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">71</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Favaloro, Emmanuel J.</author><author>Lippi, Giuseppe</author></authors></contributors><titles><title>Recommendations for Minimal Laboratory Testing Panels in Patients with COVID-19: Potential for Prognostic Monitoring</title><secondary-title>Semin Thromb Hemost</secondary-title></titles><periodical><full-title>Semin Thromb Hemost</full-title></periodical><pages>379-382</pages><volume>41</volume><number>03</number><edition>12.04.2020</edition><section>379</section><dates><year>2020</year><pub-dates><date>//21.04.2020</date></pub-dates></dates><isbn>0094-6176</isbn><urls></urls><electronic-resource-num>10.1055/s-0040-1709498</electronic-resource-num><language>En</language></record></Cite></EndNote>(1). اگر چه کووید-19 به طور کلی یک بیماری حاد قابل درمان است، اما در عین حال می‌تواند با میزان مرگ و میر 2 درصد کشنده باشد PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YdTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051 bT43MDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMik8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJlYy1u dW1iZXI+NzA8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlkPSI5 cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjcwPC9rZXk+PC9mb3JlaWduLWtl eXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250cmli dXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5YdSwgWi48L2F1dGhvcj48YXV0aG9yPlNoaSwgTC48L2F1 dGhvcj48YXV0aG9yPldhbmcsIFkuPC9hdXRob3I+PGF1dGhvcj5aaGFuZywgSi48L2F1dGhvcj48 YXV0aG9yPkh1YW5nLCBMLjwvYXV0aG9yPjxhdXRob3I+WmhhbmcsIEMuPC9hdXRob3I+PGF1dGhv cj5MaXUsIFMuPC9hdXRob3I+PGF1dGhvcj5aaGFvLCBQLjwvYXV0aG9yPjxhdXRob3I+TGl1LCBI LjwvYXV0aG9yPjxhdXRob3I+Wmh1LCBMLjwvYXV0aG9yPjxhdXRob3I+VGFpLCBZLjwvYXV0aG9y PjxhdXRob3I+QmFpLCBDLjwvYXV0aG9yPjxhdXRob3I+R2FvLCBULjwvYXV0aG9yPjxhdXRob3I+ U29uZywgSi48L2F1dGhvcj48YXV0aG9yPlhpYSwgUC48L2F1dGhvcj48YXV0aG9yPkRvbmcsIEou PC9hdXRob3I+PGF1dGhvcj5aaGFvLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgRi4gUy48L2F1 dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5UcmVhdG1lbnQgYW5k IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGlj YWwgQ2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNl YXJjaCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGlu YS4mI3hEO0RlcGFydG1lbnQgb2YgUGF0aG9sb2d5IGFuZCBIZXBhdG9sb2d5LCBUaGUgRmlmdGgg TWVkaWNhbCBDZW50ZXIgb2YgUExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2Fs IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzks IENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSZXNwaXJhdGlvbiwgVGhlIEZpZnRoIE1lZGljYWwg Q2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJj aCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4m I3hEO0RlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBUaGUgRmlmdGggTWVkaWNhbCBDZW50ZXIgb2Yg UExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRlciBm b3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzksIENoaW5hLiYjeEQ7RGVwYXJ0 bWVudCBvZiBQYXRob2xvZ3kgYW5kIEhlcGF0b2xvZ3ksIFRoZSBGaWZ0aCBNZWRpY2FsIENlbnRl ciBvZiBQTEEgR2VuZXJhbCBIb3NwaXRhbCwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2Vu dGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vhc2VzLCBCZWlqaW5nIDEwMDAzOSwgQ2hpbmEuIEVsZWN0 cm9uaWMgYWRkcmVzczogam16aGFvMzAyQDE2My5jb20uJiN4RDtUcmVhdG1lbnQgYW5kIFJlc2Vh cmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGljYWwgQ2Vu dGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4gRWxl Y3Ryb25pYyBhZGRyZXNzOiBmc3dhbmczMDJAMTYzLmNvbS48L2F1dGgtYWRkcmVzcz48dGl0bGVz Pjx0aXRsZT5QYXRob2xvZ2ljYWwgZmluZGluZ3Mgb2YgQ09WSUQtMTkgYXNzb2NpYXRlZCB3aXRo IGFjdXRlIHJlc3BpcmF0b3J5IGRpc3RyZXNzIHN5bmRyb21lPC90aXRsZT48c2Vjb25kYXJ5LXRp dGxlPkxhbmNldCBSZXNwaXIgTWVkPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5UaGUgTGFu Y2V0LiBSZXNwaXJhdG9yeSBtZWRpY2luZTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2Fs PjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+VGhlIExh bmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJp b2RpY2FsPjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+ VGhlIExhbmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2Fs PjxwYWdlcz40MjAtNDIyPC9wYWdlcz48dm9sdW1lPjg8L3ZvbHVtZT48bnVtYmVyPjQ8L251bWJl cj48ZWRpdGlvbj4yMDIwLzAyLzIzPC9lZGl0aW9uPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxw dWItZGF0ZXM+PGRhdGU+QXByPC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MjIxMy0y NjAwIChQcmludCkmI3hEOzIyMTMtMjYwMDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjA4NTg0Njwv YWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGN1c3RvbTI+UG1jNzE2NDc3MTwvY3VzdG9tMj48 ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9zMjIxMy0yNjAwKDIwKTMwMDc2LXg8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1v dGUtZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9D aXRlPjwvRW5kTm90ZT5= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YdTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051 bT43MDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMik8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJlYy1u dW1iZXI+NzA8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlkPSI5 cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjcwPC9rZXk+PC9mb3JlaWduLWtl eXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250cmli dXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5YdSwgWi48L2F1dGhvcj48YXV0aG9yPlNoaSwgTC48L2F1 dGhvcj48YXV0aG9yPldhbmcsIFkuPC9hdXRob3I+PGF1dGhvcj5aaGFuZywgSi48L2F1dGhvcj48 YXV0aG9yPkh1YW5nLCBMLjwvYXV0aG9yPjxhdXRob3I+WmhhbmcsIEMuPC9hdXRob3I+PGF1dGhv cj5MaXUsIFMuPC9hdXRob3I+PGF1dGhvcj5aaGFvLCBQLjwvYXV0aG9yPjxhdXRob3I+TGl1LCBI LjwvYXV0aG9yPjxhdXRob3I+Wmh1LCBMLjwvYXV0aG9yPjxhdXRob3I+VGFpLCBZLjwvYXV0aG9y PjxhdXRob3I+QmFpLCBDLjwvYXV0aG9yPjxhdXRob3I+R2FvLCBULjwvYXV0aG9yPjxhdXRob3I+ U29uZywgSi48L2F1dGhvcj48YXV0aG9yPlhpYSwgUC48L2F1dGhvcj48YXV0aG9yPkRvbmcsIEou PC9hdXRob3I+PGF1dGhvcj5aaGFvLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgRi4gUy48L2F1 dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5UcmVhdG1lbnQgYW5k IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGlj YWwgQ2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNl YXJjaCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGlu YS4mI3hEO0RlcGFydG1lbnQgb2YgUGF0aG9sb2d5IGFuZCBIZXBhdG9sb2d5LCBUaGUgRmlmdGgg TWVkaWNhbCBDZW50ZXIgb2YgUExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2Fs IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzks IENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSZXNwaXJhdGlvbiwgVGhlIEZpZnRoIE1lZGljYWwg Q2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJj aCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4m I3hEO0RlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBUaGUgRmlmdGggTWVkaWNhbCBDZW50ZXIgb2Yg UExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRlciBm b3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzksIENoaW5hLiYjeEQ7RGVwYXJ0 bWVudCBvZiBQYXRob2xvZ3kgYW5kIEhlcGF0b2xvZ3ksIFRoZSBGaWZ0aCBNZWRpY2FsIENlbnRl ciBvZiBQTEEgR2VuZXJhbCBIb3NwaXRhbCwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2Vu dGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vhc2VzLCBCZWlqaW5nIDEwMDAzOSwgQ2hpbmEuIEVsZWN0 cm9uaWMgYWRkcmVzczogam16aGFvMzAyQDE2My5jb20uJiN4RDtUcmVhdG1lbnQgYW5kIFJlc2Vh cmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGljYWwgQ2Vu dGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4gRWxl Y3Ryb25pYyBhZGRyZXNzOiBmc3dhbmczMDJAMTYzLmNvbS48L2F1dGgtYWRkcmVzcz48dGl0bGVz Pjx0aXRsZT5QYXRob2xvZ2ljYWwgZmluZGluZ3Mgb2YgQ09WSUQtMTkgYXNzb2NpYXRlZCB3aXRo IGFjdXRlIHJlc3BpcmF0b3J5IGRpc3RyZXNzIHN5bmRyb21lPC90aXRsZT48c2Vjb25kYXJ5LXRp dGxlPkxhbmNldCBSZXNwaXIgTWVkPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5UaGUgTGFu Y2V0LiBSZXNwaXJhdG9yeSBtZWRpY2luZTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2Fs PjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+VGhlIExh bmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJp b2RpY2FsPjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+ VGhlIExhbmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2Fs PjxwYWdlcz40MjAtNDIyPC9wYWdlcz48dm9sdW1lPjg8L3ZvbHVtZT48bnVtYmVyPjQ8L251bWJl cj48ZWRpdGlvbj4yMDIwLzAyLzIzPC9lZGl0aW9uPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxw dWItZGF0ZXM+PGRhdGU+QXByPC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MjIxMy0y NjAwIChQcmludCkmI3hEOzIyMTMtMjYwMDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjA4NTg0Njwv YWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGN1c3RvbTI+UG1jNzE2NDc3MTwvY3VzdG9tMj48 ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9zMjIxMy0yNjAwKDIwKTMwMDc2LXg8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1v dGUtZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9D aXRlPjwvRW5kTm90ZT5= ADDIN EN.CITE.DATA (2). هرچند میزان مرگ و میر ناشی از آن تاکنون کمتر از بیماریهای سارس یا مرس بوده‌ است؛ اما با اینحال، این ویروس بسیار عفونتزا بوده و به عنوان یک تهدید قابل توجه برای سلامتی بشمار میرود ADDIN EN.CITE <EndNote><Cite><Author>Shi</Author><Year>2020</Year><RecNum>10</RecNum><DisplayText>(3)</DisplayText><record><rec-number>10</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">10</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Shi, Heshui</author><author>Han, Xiaoyu</author><author>Jiang, Nanchuan</author><author>Cao, Yukun</author><author>Alwalid, Osamah</author><author>Gu, Jin</author><author>Fan, Yanqing</author><author>Zheng, Chuansheng</author></authors></contributors><titles><title>Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study</title><secondary-title>The Lancet Infectious Diseases</secondary-title></titles><periodical><full-title>The Lancet Infectious Diseases</full-title></periodical><dates><year>2020</year></dates><isbn>1473-3099</isbn><urls></urls></record></Cite></EndNote>(3). بیشتر علائم بالینی این بیماری غیر اختصاصی هستند، اما توجه به علائم بالینی کووید-19 مهم است ADDIN EN.CITE <EndNote><Cite><Author>Zu</Author><Year>2020</Year><RecNum>16</RecNum><DisplayText>(4)</DisplayText><record><rec-number>16</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">16</key><key app="ENWeb" db-id="">0</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Zu, Zi Yue</author><author>Jiang, Meng Di</author><author>Xu, Peng Peng</author><author>Chen, Wen</author><author>Ni, Qian Qian</author><author>Lu, Guang Ming</author><author>Zhang, Long Jiang</author></authors></contributors><titles><title>Coronavirus disease 2019 (COVID-19): a perspective from China</title><secondary-title>Radiology</secondary-title></titles><periodical><full-title>Radiology</full-title></periodical><pages>200490</pages><dates><year>2020</year></dates><isbn>0033-8419</isbn><urls></urls></record></Cite></EndNote>(4).با توجه به ناشناخته بودن بیماری، نکته مهم این است که تفاوتهای قابل توجهی در ویژگیهای بالینی و جمعیتی بیماران مبتلا به کووید-19 در مناطق مختلف جهان مشاهده شده‌است ADDIN EN.CITE <EndNote><Cite><Author>Aggarwal</Author><Year>2020</Year><RecNum>137</RecNum><DisplayText>(5)</DisplayText><record><rec-number>137</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">137</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Aggarwal, Saurabh</author><author>Garcia-Telles, Nelson</author><author>Aggarwal, Gaurav</author><author>Lavie, Carl</author><author>Lippi, Giuseppe</author><author>Henry, Brandon Michael</author></authors></contributors><titles><title>Clinical features, laboratory characteristics, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19): Early report from the United States</title><secondary-title>Diagnosis</secondary-title></titles><periodical><full-title>Diagnosis</full-title></periodical><pages>91-96</pages><volume>7</volume><number>2</number><dates><year>2020</year></dates><isbn>2194-8011</isbn><urls></urls></record></Cite></EndNote>(5). نتایج مطالعات همچنین نشان می‌دهند بین ویژگیهای بالینی، آزمایشگاهی و اپیدمیولوژیکی افراد متوفی و بازمانده تفاوت معنیداری وجود دارد ADDIN EN.CITE <EndNote><Cite><Author>Yang</Author><Year>2020</Year><RecNum>5</RecNum><DisplayText>(6)</DisplayText><record><rec-number>5</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">5</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Yang, Xiaobo</author><author>Yu, Yuan</author><author>Xu, Jiqian</author><author>Shu, Huaqing</author><author>Xia, Jia'an</author><author>Liu, Hong</author><author>Wu, Yongran</author><author>Zhang, Lu</author><author>Yu, Zhui</author><author>Fang, Minghao</author><author>Yu, Ting</author><author>Wang, Yaxin</author><author>Pan, Shangwen</author><author>Zou, Xiaojing</author><author>Yuan, Shiying</author><author>Shang, You</author></authors></contributors><titles><title>Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study</title><secondary-title>The Lancet Respiratory Medicine</secondary-title></titles><periodical><full-title>The Lancet Respiratory Medicine</full-title></periodical><pages>475-481</pages><volume>8</volume><number>5</number><dates><year>2020</year><pub-dates><date>2020/05/01/</date></pub-dates></dates><isbn>2213-2600</isbn><urls><related-urls><url>http://www.sciencedirect.com/science/article/pii/S2213260020300795</url></related-urls></urls><electronic-resource-num>https://doi.org/10.1016/S2213-2600(20)30079-5</electronic-resource-num></record></Cite></EndNote>(6). تخمین زده میشود دورهی نهفتگی عفونت ناشی از کووید-19، بین 2 تا 14 روز متغیر بوده و به طور متوسط علایم ظرف مدت 5 تا 2 روز ظاهر میشود ADDIN EN.CITE <EndNote><Cite><Author>Lai</Author><Year>2020</Year><RecNum>58</RecNum><DisplayText>(7)</DisplayText><record><rec-number>58</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">58</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Lai, Chih-Cheng</author><author>Shih, Tzu-Ping</author><author>Ko, Wen-Chien</author><author>Tang, Hung-Jen</author><author>Hsueh, Po-Ren</author></authors></contributors><titles><title>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges</title><secondary-title>International Journal of Antimicrobial Agents</secondary-title></titles><periodical><full-title>International Journal of Antimicrobial Agents</full-title></periodical><pages>105924</pages><volume>55</volume><number>3</number><keywords><keyword>2019-nCoV</keyword><keyword>SARS-CoV-2</keyword><keyword>COVID-19</keyword><keyword>China</keyword><keyword>Epidemic</keyword><keyword>Remdesivir</keyword></keywords><dates><year>2020</year><pub-dates><date>2020/03/01/</date></pub-dates></dates><isbn>0924-8579</isbn><urls><related-urls><url>http://www.sciencedirect.com/science/article/pii/S0924857920300674</url></related-urls></urls><electronic-resource-num>https://doi.org/10.1016/j.ijantimicag.2020.105924</electronic-resource-num></record></Cite></EndNote>(7).نتایج مطالعات مختلف نشان میدهد علائم شایع شامل تب، سرفه و میالژی یا خستگی و تنگینفس می‌باشد ADDIN EN.CITE <EndNote><Cite><Author>Zu</Author><Year>2020</Year><RecNum>59</RecNum><DisplayText>(8)</DisplayText><record><rec-number>59</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">59</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Zu, Z. Y.</author><author>Jiang, M. D.</author><author>Xu, P. P.</author><author>Chen, W.</author><author>Ni, Q. Q.</author></authors></contributors><auth-address>From the Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China (Z.Y.Z., M.D.J., P.P.X., Q.Q.N., G.M.L., L.J.Z.); and Department of Medical Imaging, Taihe Hospital, Shiyan, Hubei, China (W.C.).</auth-address><titles><title>Coronavirus Disease 2019 (COVID-19): A Perspective from China</title></titles><pages>E15-e25</pages><volume>296</volume><number>2</number><dates><year>2020</year><pub-dates><date>Aug</date></pub-dates></dates><isbn>0033-8419 (Print)0033-8419</isbn><accession-num>32083985</accession-num><urls></urls><electronic-resource-num>10.1148/radiol.2020200490</electronic-resource-num><remote-database-provider>Nlm</remote-database-provider></record></Cite></EndNote>(8). همچنین در مطالعاتی دیگر بروز تهوع و استفراغ نیز به‌عنوان علائم بیماری ذکر شده‌ است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE.DATA (9). در مطالعات به طور متعدد، به وجود ارتباط بین سن بالا و افزایش میزان مرگ و میر، در مبتلایان به کووید-19 اشاره شده است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjI2PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxMCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+MjY8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjI2PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaG91LCBGLjwvYXV0aG9yPjxhdXRob3I+WXUsIFQu PC9hdXRob3I+PGF1dGhvcj5EdSwgUi48L2F1dGhvcj48YXV0aG9yPkZhbiwgRy48L2F1dGhvcj48 YXV0aG9yPkxpdSwgWS48L2F1dGhvcj48YXV0aG9yPkxpdSwgWi48L2F1dGhvcj48YXV0aG9yPlhp YW5nLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgWS48L2F1dGhvcj48YXV0aG9yPlNvbmcsIEIu PC9hdXRob3I+PGF1dGhvcj5HdSwgWC48L2F1dGhvcj48YXV0aG9yPkd1YW4sIEwuPC9hdXRob3I+ PGF1dGhvcj5XZWksIFkuPC9hdXRob3I+PGF1dGhvcj5MaSwgSC48L2F1dGhvcj48YXV0aG9yPld1 LCBYLjwvYXV0aG9yPjxhdXRob3I+WHUsIEouPC9hdXRob3I+PGF1dGhvcj5UdSwgUy48L2F1dGhv cj48YXV0aG9yPlpoYW5nLCBZLjwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgSC48L2F1dGhvcj48YXV0 aG9yPkNhbywgQi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVz cz5EZXBhcnRtZW50IG9mIFB1bG1vbmFyeSBhbmQgQ3JpdGljYWwgQ2FyZSBNZWRpY2luZSwgQ2Vu dGVyIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIFJlc3BpcmF0b3J5IERpc2Vhc2VzLCBJbnN0aXR1dGUgb2YgUmVzcGlyYXRvcnkg TWVkaWNpbmUsIENoaW5lc2UgQWNhZGVteSBvZiBNZWRpY2FsIFNjaWVuY2VzLCBQZWtpbmcgVW5p b24gTWVkaWNhbCBDb2xsZWdlLCBCZWlqaW5nLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgVHVi ZXJjdWxvc2lzIGFuZCBSZXNwaXJhdG9yeSBEaXNlYXNlLCBKaW55aW50YW4gSG9zcGl0YWwsIFd1 aGFuLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJl IE1lZGljaW5lLCBXdWhhbiBQdWxtb25hcnkgSG9zcGl0YWwsIFd1aGFuLCBDaGluYS4mI3hEO0Rl cGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJlIE1lZGljaW5lLCBDZW50ZXIg b2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRl ciBmb3IgUmVzcGlyYXRvcnkgRGlzZWFzZXMsIEluc3RpdHV0ZSBvZiBSZXNwaXJhdG9yeSBNZWRp Y2luZSwgQ2hpbmVzZSBBY2FkZW15IG9mIE1lZGljYWwgU2NpZW5jZXMsIFBla2luZyBVbmlvbiBN ZWRpY2FsIENvbGxlZ2UsIEJlaWppbmcsIENoaW5hOyBJbnN0aXR1dGUgb2YgQ2xpbmljYWwgTWVk aWNhbCBTY2llbmNlcywgQ2hpbmEtSmFwYW4gRnJpZW5kc2hpcCBIb3NwaXRhbCwgQmVpamluZywg Q2hpbmEuJiN4RDtEZXBhcnRtZW50IG9mIENsaW5pY2FsIExhYm9yYXRvcnksIEppbnlpbnRhbiBI b3NwaXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBQdWxtb25hcnkgYW5kIENy aXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgTmF0 aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJhdG9yeSBEaXNlYXNlcywg SW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNlIEFjYWRlbXkgb2YgTWVk aWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVnZSwgQmVpamluZywgQ2hp bmE7IERlcGFydG1lbnQgb2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIENhcGl0YWwgTWVkaWNhbCBV bml2ZXJzaXR5LCBCZWlqaW5nLCBDaGluYS4mI3hEO0dDUCBDZW50ZXIsIEppbnlpbnRhbiBIb3Nw aXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7VHNpbmdodWEgVW5pdmVyc2l0eSBTY2hvb2wgb2YgTWVk aWNpbmUsIEJlaWppbmcsIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBUdWJlcmN1bG9zaXMgYW5k IFJlc3BpcmF0b3J5IERpc2Vhc2UsIEppbnlpbnRhbiBIb3NwaXRhbCwgV3VoYW4sIENoaW5hLiBF bGVjdHJvbmljIGFkZHJlc3M6IDI3MTY2Mzc5NDdAcXEuY29tLiYjeEQ7RGVwYXJ0bWVudCBvZiBQ dWxtb25hcnkgYW5kIENyaXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9y eSBNZWRpY2luZSwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJh dG9yeSBEaXNlYXNlcywgSW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNl IEFjYWRlbXkgb2YgTWVkaWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVn ZSwgQmVpamluZywgQ2hpbmE7IERlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBD YXJlIE1lZGljaW5lLCBDaGluYS1KYXBhbiBGcmllbmRzaGlwIEhvc3BpdGFsLCBCZWlqaW5nLCBD aGluYTsgRGVwYXJ0bWVudCBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgQ2FwaXRhbCBNZWRpY2Fs IFVuaXZlcnNpdHksIEJlaWppbmcsIENoaW5hOyBUc2luZ2h1YSBVbml2ZXJzaXR5IFNjaG9vbCBv ZiBNZWRpY2luZSwgQmVpamluZywgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2FvYmluX2Jl bkAxNjMuY29tLjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2FsIGNvdXJzZSBh bmQgcmlzayBmYWN0b3JzIGZvciBtb3J0YWxpdHkgb2YgYWR1bHQgaW5wYXRpZW50cyB3aXRoIENP VklELTE5IGluIFd1aGFuLCBDaGluYTogYSByZXRyb3NwZWN0aXZlIGNvaG9ydCBzdHVkeTwvdGl0 bGU+PHNlY29uZGFyeS10aXRsZT5MYW5jZXQ8L3NlY29uZGFyeS10aXRsZT48YWx0LXRpdGxlPkxh bmNldCAoTG9uZG9uLCBFbmdsYW5kKTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkxhbmNldDwvZnVsbC10aXRsZT48YWJici0xPkxhbmNldCAoTG9uZG9uLCBFbmds YW5kKTwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TGFu Y2V0PC9mdWxsLXRpdGxlPjxhYmJyLTE+TGFuY2V0IChMb25kb24sIEVuZ2xhbmQpPC9hYmJyLTE+ PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+MTA1NC0xMDYyPC9wYWdlcz48dm9sdW1lPjM5NTwvdm9s dW1lPjxudW1iZXI+MTAyMjk8L251bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzE1PC9lZGl0aW9uPjxr ZXl3b3Jkcz48a2V5d29yZD5BZG9sZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3 b3JkPjxrZXl3b3JkPkFnZSBGYWN0b3JzPC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+ PGtleXdvcmQ+QWdlZCwgODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtleXdvcmQ+QmV0YWNvcm9uYXZp cnVzPC9rZXl3b3JkPjxrZXl3b3JkPkNhcmRpb3Zhc2N1bGFyIERpc2Vhc2VzL2NvbXBsaWNhdGlv bnM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdvcmQ+Q2xpbmljYWwgTGFi b3JhdG9yeSBUZWNobmlxdWVzPC9rZXl3b3JkPjxrZXl3b3JkPkNvaG9ydCBTdHVkaWVzPC9rZXl3 b3JkPjxrZXl3b3JkPkNvbW9yYmlkaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIElu ZmVjdGlvbnMvY29tcGxpY2F0aW9ucy9kaWFnbm9zaXMvKm1vcnRhbGl0eTwva2V5d29yZD48a2V5 d29yZD5EaWFiZXRlcyBDb21wbGljYXRpb25zPC9rZXl3b3JkPjxrZXl3b3JkPkRpc2Vhc2UgUHJv Z3Jlc3Npb248L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkZpYnJp biBGaWJyaW5vZ2VuIERlZ3JhZGF0aW9uIFByb2R1Y3RzL2FuYWx5c2lzPC9rZXl3b3JkPjxrZXl3 b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5IeXBlcnRlbnNpb24vY29tcGxpY2F0aW9uczwv a2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3b3JkPk1pZGRsZSBBZ2VkPC9rZXl3 b3JkPjxrZXl3b3JkPk1vcnRhbGl0eS90cmVuZHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk9yZ2FuIER5 c2Z1bmN0aW9uIFNjb3Jlczwva2V5d29yZD48a2V5d29yZD5QYW5kZW1pY3M8L2tleXdvcmQ+PGtl eXdvcmQ+KlBhdGllbnQgQ2FyZSBQbGFubmluZzwva2V5d29yZD48a2V5d29yZD5QYXRpZW50IElz b2xhdGlvbjwva2V5d29yZD48a2V5d29yZD5QbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMv ZGlhZ25vc2lzLyptb3J0YWxpdHk8L2tleXdvcmQ+PGtleXdvcmQ+UHJvZ25vc2lzPC9rZXl3b3Jk PjxrZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD4qUmlzayBB c3Nlc3NtZW50L21ldGhvZHM8L2tleXdvcmQ+PGtleXdvcmQ+UmlzayBGYWN0b3JzPC9rZXl3b3Jk PjxrZXl3b3JkPllvdW5nIEFkdWx0PC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIw MjA8L3llYXI+PHB1Yi1kYXRlcz48ZGF0ZT5NYXIgMjg8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRl cz48aXNibj4wMTQwLTY3MzYgKFByaW50KSYjeEQ7MDE0MC02NzM2PC9pc2JuPjxhY2Nlc3Npb24t bnVtPjMyMTcxMDc2PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM3Mjcw NjI3PC9jdXN0b20yPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L3MwMTQwLTY3MzYo MjApMzA1NjYtMzwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1wcm92 aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFn ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjI2PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxMCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+MjY8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjI2PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaG91LCBGLjwvYXV0aG9yPjxhdXRob3I+WXUsIFQu PC9hdXRob3I+PGF1dGhvcj5EdSwgUi48L2F1dGhvcj48YXV0aG9yPkZhbiwgRy48L2F1dGhvcj48 YXV0aG9yPkxpdSwgWS48L2F1dGhvcj48YXV0aG9yPkxpdSwgWi48L2F1dGhvcj48YXV0aG9yPlhp YW5nLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgWS48L2F1dGhvcj48YXV0aG9yPlNvbmcsIEIu PC9hdXRob3I+PGF1dGhvcj5HdSwgWC48L2F1dGhvcj48YXV0aG9yPkd1YW4sIEwuPC9hdXRob3I+ PGF1dGhvcj5XZWksIFkuPC9hdXRob3I+PGF1dGhvcj5MaSwgSC48L2F1dGhvcj48YXV0aG9yPld1 LCBYLjwvYXV0aG9yPjxhdXRob3I+WHUsIEouPC9hdXRob3I+PGF1dGhvcj5UdSwgUy48L2F1dGhv cj48YXV0aG9yPlpoYW5nLCBZLjwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgSC48L2F1dGhvcj48YXV0 aG9yPkNhbywgQi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVz cz5EZXBhcnRtZW50IG9mIFB1bG1vbmFyeSBhbmQgQ3JpdGljYWwgQ2FyZSBNZWRpY2luZSwgQ2Vu dGVyIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIFJlc3BpcmF0b3J5IERpc2Vhc2VzLCBJbnN0aXR1dGUgb2YgUmVzcGlyYXRvcnkg TWVkaWNpbmUsIENoaW5lc2UgQWNhZGVteSBvZiBNZWRpY2FsIFNjaWVuY2VzLCBQZWtpbmcgVW5p b24gTWVkaWNhbCBDb2xsZWdlLCBCZWlqaW5nLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgVHVi ZXJjdWxvc2lzIGFuZCBSZXNwaXJhdG9yeSBEaXNlYXNlLCBKaW55aW50YW4gSG9zcGl0YWwsIFd1 aGFuLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJl IE1lZGljaW5lLCBXdWhhbiBQdWxtb25hcnkgSG9zcGl0YWwsIFd1aGFuLCBDaGluYS4mI3hEO0Rl cGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJlIE1lZGljaW5lLCBDZW50ZXIg b2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRl ciBmb3IgUmVzcGlyYXRvcnkgRGlzZWFzZXMsIEluc3RpdHV0ZSBvZiBSZXNwaXJhdG9yeSBNZWRp Y2luZSwgQ2hpbmVzZSBBY2FkZW15IG9mIE1lZGljYWwgU2NpZW5jZXMsIFBla2luZyBVbmlvbiBN ZWRpY2FsIENvbGxlZ2UsIEJlaWppbmcsIENoaW5hOyBJbnN0aXR1dGUgb2YgQ2xpbmljYWwgTWVk aWNhbCBTY2llbmNlcywgQ2hpbmEtSmFwYW4gRnJpZW5kc2hpcCBIb3NwaXRhbCwgQmVpamluZywg Q2hpbmEuJiN4RDtEZXBhcnRtZW50IG9mIENsaW5pY2FsIExhYm9yYXRvcnksIEppbnlpbnRhbiBI b3NwaXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBQdWxtb25hcnkgYW5kIENy aXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgTmF0 aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJhdG9yeSBEaXNlYXNlcywg SW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNlIEFjYWRlbXkgb2YgTWVk aWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVnZSwgQmVpamluZywgQ2hp bmE7IERlcGFydG1lbnQgb2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIENhcGl0YWwgTWVkaWNhbCBV bml2ZXJzaXR5LCBCZWlqaW5nLCBDaGluYS4mI3hEO0dDUCBDZW50ZXIsIEppbnlpbnRhbiBIb3Nw aXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7VHNpbmdodWEgVW5pdmVyc2l0eSBTY2hvb2wgb2YgTWVk aWNpbmUsIEJlaWppbmcsIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBUdWJlcmN1bG9zaXMgYW5k IFJlc3BpcmF0b3J5IERpc2Vhc2UsIEppbnlpbnRhbiBIb3NwaXRhbCwgV3VoYW4sIENoaW5hLiBF bGVjdHJvbmljIGFkZHJlc3M6IDI3MTY2Mzc5NDdAcXEuY29tLiYjeEQ7RGVwYXJ0bWVudCBvZiBQ dWxtb25hcnkgYW5kIENyaXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9y eSBNZWRpY2luZSwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJh dG9yeSBEaXNlYXNlcywgSW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNl IEFjYWRlbXkgb2YgTWVkaWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVn ZSwgQmVpamluZywgQ2hpbmE7IERlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBD YXJlIE1lZGljaW5lLCBDaGluYS1KYXBhbiBGcmllbmRzaGlwIEhvc3BpdGFsLCBCZWlqaW5nLCBD aGluYTsgRGVwYXJ0bWVudCBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgQ2FwaXRhbCBNZWRpY2Fs IFVuaXZlcnNpdHksIEJlaWppbmcsIENoaW5hOyBUc2luZ2h1YSBVbml2ZXJzaXR5IFNjaG9vbCBv ZiBNZWRpY2luZSwgQmVpamluZywgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2FvYmluX2Jl bkAxNjMuY29tLjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2FsIGNvdXJzZSBh bmQgcmlzayBmYWN0b3JzIGZvciBtb3J0YWxpdHkgb2YgYWR1bHQgaW5wYXRpZW50cyB3aXRoIENP VklELTE5IGluIFd1aGFuLCBDaGluYTogYSByZXRyb3NwZWN0aXZlIGNvaG9ydCBzdHVkeTwvdGl0 bGU+PHNlY29uZGFyeS10aXRsZT5MYW5jZXQ8L3NlY29uZGFyeS10aXRsZT48YWx0LXRpdGxlPkxh bmNldCAoTG9uZG9uLCBFbmdsYW5kKTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkxhbmNldDwvZnVsbC10aXRsZT48YWJici0xPkxhbmNldCAoTG9uZG9uLCBFbmds YW5kKTwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TGFu Y2V0PC9mdWxsLXRpdGxlPjxhYmJyLTE+TGFuY2V0IChMb25kb24sIEVuZ2xhbmQpPC9hYmJyLTE+ PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+MTA1NC0xMDYyPC9wYWdlcz48dm9sdW1lPjM5NTwvdm9s dW1lPjxudW1iZXI+MTAyMjk8L251bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzE1PC9lZGl0aW9uPjxr ZXl3b3Jkcz48a2V5d29yZD5BZG9sZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3 b3JkPjxrZXl3b3JkPkFnZSBGYWN0b3JzPC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+ PGtleXdvcmQ+QWdlZCwgODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtleXdvcmQ+QmV0YWNvcm9uYXZp cnVzPC9rZXl3b3JkPjxrZXl3b3JkPkNhcmRpb3Zhc2N1bGFyIERpc2Vhc2VzL2NvbXBsaWNhdGlv bnM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdvcmQ+Q2xpbmljYWwgTGFi b3JhdG9yeSBUZWNobmlxdWVzPC9rZXl3b3JkPjxrZXl3b3JkPkNvaG9ydCBTdHVkaWVzPC9rZXl3 b3JkPjxrZXl3b3JkPkNvbW9yYmlkaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIElu ZmVjdGlvbnMvY29tcGxpY2F0aW9ucy9kaWFnbm9zaXMvKm1vcnRhbGl0eTwva2V5d29yZD48a2V5 d29yZD5EaWFiZXRlcyBDb21wbGljYXRpb25zPC9rZXl3b3JkPjxrZXl3b3JkPkRpc2Vhc2UgUHJv Z3Jlc3Npb248L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkZpYnJp biBGaWJyaW5vZ2VuIERlZ3JhZGF0aW9uIFByb2R1Y3RzL2FuYWx5c2lzPC9rZXl3b3JkPjxrZXl3 b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5IeXBlcnRlbnNpb24vY29tcGxpY2F0aW9uczwv a2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3b3JkPk1pZGRsZSBBZ2VkPC9rZXl3 b3JkPjxrZXl3b3JkPk1vcnRhbGl0eS90cmVuZHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk9yZ2FuIER5 c2Z1bmN0aW9uIFNjb3Jlczwva2V5d29yZD48a2V5d29yZD5QYW5kZW1pY3M8L2tleXdvcmQ+PGtl eXdvcmQ+KlBhdGllbnQgQ2FyZSBQbGFubmluZzwva2V5d29yZD48a2V5d29yZD5QYXRpZW50IElz b2xhdGlvbjwva2V5d29yZD48a2V5d29yZD5QbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMv ZGlhZ25vc2lzLyptb3J0YWxpdHk8L2tleXdvcmQ+PGtleXdvcmQ+UHJvZ25vc2lzPC9rZXl3b3Jk PjxrZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD4qUmlzayBB c3Nlc3NtZW50L21ldGhvZHM8L2tleXdvcmQ+PGtleXdvcmQ+UmlzayBGYWN0b3JzPC9rZXl3b3Jk PjxrZXl3b3JkPllvdW5nIEFkdWx0PC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIw MjA8L3llYXI+PHB1Yi1kYXRlcz48ZGF0ZT5NYXIgMjg8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRl cz48aXNibj4wMTQwLTY3MzYgKFByaW50KSYjeEQ7MDE0MC02NzM2PC9pc2JuPjxhY2Nlc3Npb24t bnVtPjMyMTcxMDc2PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM3Mjcw NjI3PC9jdXN0b20yPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L3MwMTQwLTY3MzYo MjApMzA1NjYtMzwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1wcm92 aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFn ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE.DATA (10). دیگر مطالعات نیز گزارش دادهاند که، وجود بیماریهای زمینهای، نظیر فشارخون بالا PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5MaXBwaTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT43NDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTEpPC9EaXNwbGF5VGV4dD48cmVjb3JkPjxy ZWMtbnVtYmVyPjc0PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBkYi1p ZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj43NDwva2V5PjwvZm9yZWln bi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29u dHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+TGlwcGksIEcuPC9hdXRob3I+PGF1dGhvcj5Xb25n LCBKLjwvYXV0aG9yPjxhdXRob3I+SGVucnksIEIuIE0uPC9hdXRob3I+PC9hdXRob3JzPjwvY29u dHJpYnV0b3JzPjxhdXRoLWFkZHJlc3M+U2VjdGlvbiBvZiBDbGluaWNhbCBCaW9jaGVtaXN0cnks IERlcGFydG1lbnQgb2YgTmV1cm9zY2llbmNlLCBCaW9tZWRpY2luZSBhbmQgTW92ZW1lbnQsIFVu aXZlcnNpdHkgb2YgVmVyb25hLCBWZXJvbmEsIEl0YWx5LiBnaXVzZXBwZS5saXBwaUB1bml2ci5p dCYjeEQ7Q29sbGVnZSBvZiBNZWRpY2luZSwgU1VOWSBEb3duc3RhdGUgSGVhbHRoIFNjaWVuY2Vz IFVuaXZlcnNpdHksIE5ldyBZb3JrLCBVbml0ZWQgU3RhdGVzJiN4RDtDYXJkaWFjIEludGVuc2l2 ZSBDYXJlIFVuaXQsIFRoZSBIZWFydCBJbnN0aXR1dGUsIENpbmNpbm5hdGkgQ2hpbGRyZW7igJlz IEhvc3BpdGFsIE1lZGljYWwgQ2VudGVyLCBDaW5jaW5uYXRpLCBPaGlvLCBVbml0ZWQgU3RhdGVz PC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+SHlwZXJ0ZW5zaW9uIGluIHBhdGllbnRzIHdp dGggY29yb25hdmlydXMgZGlzZWFzZSAyMDE5IChDT1ZJRC0xOSk6IGEgcG9vbGVkIGFuYWx5c2lz PC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPlBvbCBBcmNoIEludGVybiBNZWQ8L3NlY29uZGFyeS10 aXRsZT48YWx0LXRpdGxlPlBvbGlzaCBhcmNoaXZlcyBvZiBpbnRlcm5hbCBtZWRpY2luZTwvYWx0 LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBBcmNoIEludGVybiBN ZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50ZXJuYWwgbWVkaWNp bmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBB cmNoIEludGVybiBNZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50 ZXJuYWwgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdlcz4zMDQtMzA5PC9w YWdlcz48dm9sdW1lPjEzMDwvdm9sdW1lPjxudW1iZXI+NDwvbnVtYmVyPjxlZGl0aW9uPjIwMjAv MDQvMDI8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+ QmV0YWNvcm9uYXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPipDb3JvbmF2aXJ1cyBJbmZlY3Rpb25z L2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29y ZD48a2V5d29yZD4qSHlwZXJ0ZW5zaW9uL2NvbXBsaWNhdGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+ TW9ydGFsaXR5L3RyZW5kczwva2V5d29yZD48a2V5d29yZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxr ZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3Jk PjxrZXl3b3JkPlByb2dub3Npczwva2V5d29yZD48a2V5d29yZD5SaXNrIEZhY3RvcnM8L2tleXdv cmQ+PGtleXdvcmQ+U2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48L2tleXdvcmRz PjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+QXByIDMwPC9kYXRlPjwv cHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MDAzMi0zNzcyPC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMy MjMxMTcxPC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1u dW0+MTAuMjA0NTIvcGFtdy4xNTI3MjwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1k YXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPgB= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5MaXBwaTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT43NDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTEpPC9EaXNwbGF5VGV4dD48cmVjb3JkPjxy ZWMtbnVtYmVyPjc0PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBkYi1p ZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj43NDwva2V5PjwvZm9yZWln bi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29u dHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+TGlwcGksIEcuPC9hdXRob3I+PGF1dGhvcj5Xb25n LCBKLjwvYXV0aG9yPjxhdXRob3I+SGVucnksIEIuIE0uPC9hdXRob3I+PC9hdXRob3JzPjwvY29u dHJpYnV0b3JzPjxhdXRoLWFkZHJlc3M+U2VjdGlvbiBvZiBDbGluaWNhbCBCaW9jaGVtaXN0cnks IERlcGFydG1lbnQgb2YgTmV1cm9zY2llbmNlLCBCaW9tZWRpY2luZSBhbmQgTW92ZW1lbnQsIFVu aXZlcnNpdHkgb2YgVmVyb25hLCBWZXJvbmEsIEl0YWx5LiBnaXVzZXBwZS5saXBwaUB1bml2ci5p dCYjeEQ7Q29sbGVnZSBvZiBNZWRpY2luZSwgU1VOWSBEb3duc3RhdGUgSGVhbHRoIFNjaWVuY2Vz IFVuaXZlcnNpdHksIE5ldyBZb3JrLCBVbml0ZWQgU3RhdGVzJiN4RDtDYXJkaWFjIEludGVuc2l2 ZSBDYXJlIFVuaXQsIFRoZSBIZWFydCBJbnN0aXR1dGUsIENpbmNpbm5hdGkgQ2hpbGRyZW7igJlz IEhvc3BpdGFsIE1lZGljYWwgQ2VudGVyLCBDaW5jaW5uYXRpLCBPaGlvLCBVbml0ZWQgU3RhdGVz PC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+SHlwZXJ0ZW5zaW9uIGluIHBhdGllbnRzIHdp dGggY29yb25hdmlydXMgZGlzZWFzZSAyMDE5IChDT1ZJRC0xOSk6IGEgcG9vbGVkIGFuYWx5c2lz PC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPlBvbCBBcmNoIEludGVybiBNZWQ8L3NlY29uZGFyeS10 aXRsZT48YWx0LXRpdGxlPlBvbGlzaCBhcmNoaXZlcyBvZiBpbnRlcm5hbCBtZWRpY2luZTwvYWx0 LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBBcmNoIEludGVybiBN ZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50ZXJuYWwgbWVkaWNp bmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBB cmNoIEludGVybiBNZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50 ZXJuYWwgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdlcz4zMDQtMzA5PC9w YWdlcz48dm9sdW1lPjEzMDwvdm9sdW1lPjxudW1iZXI+NDwvbnVtYmVyPjxlZGl0aW9uPjIwMjAv MDQvMDI8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+ QmV0YWNvcm9uYXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPipDb3JvbmF2aXJ1cyBJbmZlY3Rpb25z L2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29y ZD48a2V5d29yZD4qSHlwZXJ0ZW5zaW9uL2NvbXBsaWNhdGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+ TW9ydGFsaXR5L3RyZW5kczwva2V5d29yZD48a2V5d29yZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxr ZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3Jk PjxrZXl3b3JkPlByb2dub3Npczwva2V5d29yZD48a2V5d29yZD5SaXNrIEZhY3RvcnM8L2tleXdv cmQ+PGtleXdvcmQ+U2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48L2tleXdvcmRz PjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+QXByIDMwPC9kYXRlPjwv cHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MDAzMi0zNzcyPC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMy MjMxMTcxPC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1u dW0+MTAuMjA0NTIvcGFtdy4xNTI3MjwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1k YXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPgB= ADDIN EN.CITE.DATA (11)، بیماریهای قلبی-عروقی یا مغزی-عروقی PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjEyNDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTIpPC9EaXNwbGF5VGV4dD48cmVjb3JkPjxy ZWMtbnVtYmVyPjEyNDwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGIt aWQ9InpmYXd6eHN3b3NmZnRqZTl0OW9wdjI1dWZ4eHR2cGVheGF0NSI+MTI0PC9rZXk+PC9mb3Jl aWduLWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxj b250cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaG91LCBGZWk8L2F1dGhvcj48YXV0aG9yPll1 LCBUaW5nPC9hdXRob3I+PGF1dGhvcj5EdSwgUm9uZ2h1aTwvYXV0aG9yPjxhdXRob3I+RmFuLCBH dW9odWk8L2F1dGhvcj48YXV0aG9yPkxpdSwgWWluZzwvYXV0aG9yPjxhdXRob3I+TGl1LCBaaGli bzwvYXV0aG9yPjxhdXRob3I+WGlhbmcsIEppZTwvYXV0aG9yPjxhdXRob3I+V2FuZywgWWVtaW5n PC9hdXRob3I+PGF1dGhvcj5Tb25nLCBCaW48L2F1dGhvcj48YXV0aG9yPkd1LCBYaWFveWluZzwv YXV0aG9yPjxhdXRob3I+R3VhbiwgTHVsdTwvYXV0aG9yPjxhdXRob3I+V2VpLCBZdWFuPC9hdXRo b3I+PGF1dGhvcj5MaSwgSHVpPC9hdXRob3I+PGF1dGhvcj5XdSwgWHVkb25nPC9hdXRob3I+PGF1 dGhvcj5YdSwgSml1eWFuZzwvYXV0aG9yPjxhdXRob3I+VHUsIFNoZW5namluPC9hdXRob3I+PGF1 dGhvcj5aaGFuZywgWWk8L2F1dGhvcj48YXV0aG9yPkNoZW4sIEh1YTwvYXV0aG9yPjxhdXRob3I+ Q2FvLCBCaW48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5E ZXBhcnRtZW50IG9mIFB1bG1vbmFyeSBhbmQgQ3JpdGljYWwgQ2FyZSBNZWRpY2luZSwgQ2VudGVy IG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBDZW50 ZXIgZm9yIFJlc3BpcmF0b3J5IERpc2Vhc2VzLCBJbnN0aXR1dGUgb2YgUmVzcGlyYXRvcnkgTWVk aWNpbmUsIENoaW5lc2UgQWNhZGVteSBvZiBNZWRpY2FsIFNjaWVuY2VzLCBQZWtpbmcgVW5pb24g TWVkaWNhbCBDb2xsZWdlLCBCZWlqaW5nLCBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0 aXRsZT5DbGluaWNhbCBjb3Vyc2UgYW5kIHJpc2sgZmFjdG9ycyBmb3IgbW9ydGFsaXR5IG9mIGFk dWx0IGlucGF0aWVudHMgd2l0aCBDT1ZJRC0xOSBpbiBXdWhhbiwgQ2hpbmE6IGEgcmV0cm9zcGVj dGl2ZSBjb2hvcnQgc3R1ZHk8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+TGFuY2V0IChMb25kb24s IEVuZ2xhbmQpPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5MYW5jZXQ8L2FsdC10aXRsZT48 L3RpdGxlcz48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TGFuY2V0PC9mdWxsLXRpdGxlPjwv YWx0LXBlcmlvZGljYWw+PHBhZ2VzPjEwNTQtMTA2MjwvcGFnZXM+PHZvbHVtZT4zOTU8L3ZvbHVt ZT48bnVtYmVyPjEwMjI5PC9udW1iZXI+PGtleXdvcmRzPjxrZXl3b3JkPlJpc2sgQXNzZXNzbWVu dDwva2V5d29yZD48a2V5d29yZD5QYXRpZW50IENhcmUgUGxhbm5pbmc8L2tleXdvcmQ+PGtleXdv cmQ+T3JnYW4gRHlzZnVuY3Rpb24gU2NvcmVzPC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5 ZWFyPjIwMjA8L3llYXI+PHB1Yi1kYXRlcz48ZGF0ZT4yMDIwLzAzLy88L2RhdGU+PC9wdWItZGF0 ZXM+PC9kYXRlcz48aXNibj4wMTQwLTY3MzY8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIxNzEwNzY8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJsPmh0dHA6Ly9ldXJvcGVwbWMu b3JnL2Fic3RyYWN0L01FRC8zMjE3MTA3NjwvdXJsPjx1cmw+aHR0cHM6Ly9kb2kub3JnLzEwLjEw MTYvUzAxNDAtNjczNigyMCkzMDU2Ni0zPC91cmw+PHVybD5odHRwczovL2V1cm9wZXBtYy5vcmcv YXJ0aWNsZXMvUE1DNzI3MDYyNzwvdXJsPjwvcmVsYXRlZC11cmxzPjwvdXJscz48ZWxlY3Ryb25p Yy1yZXNvdXJjZS1udW0+MTAuMTAxNi9zMDE0MC02NzM2KDIwKTMwNTY2LTM8L2VsZWN0cm9uaWMt cmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtbmFtZT5QdWJNZWQ8L3JlbW90ZS1kYXRhYmFz ZS1uYW1lPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjEyNDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTIpPC9EaXNwbGF5VGV4dD48cmVjb3JkPjxy ZWMtbnVtYmVyPjEyNDwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGIt aWQ9InpmYXd6eHN3b3NmZnRqZTl0OW9wdjI1dWZ4eHR2cGVheGF0NSI+MTI0PC9rZXk+PC9mb3Jl aWduLWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxj b250cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaG91LCBGZWk8L2F1dGhvcj48YXV0aG9yPll1 LCBUaW5nPC9hdXRob3I+PGF1dGhvcj5EdSwgUm9uZ2h1aTwvYXV0aG9yPjxhdXRob3I+RmFuLCBH dW9odWk8L2F1dGhvcj48YXV0aG9yPkxpdSwgWWluZzwvYXV0aG9yPjxhdXRob3I+TGl1LCBaaGli bzwvYXV0aG9yPjxhdXRob3I+WGlhbmcsIEppZTwvYXV0aG9yPjxhdXRob3I+V2FuZywgWWVtaW5n PC9hdXRob3I+PGF1dGhvcj5Tb25nLCBCaW48L2F1dGhvcj48YXV0aG9yPkd1LCBYaWFveWluZzwv YXV0aG9yPjxhdXRob3I+R3VhbiwgTHVsdTwvYXV0aG9yPjxhdXRob3I+V2VpLCBZdWFuPC9hdXRo b3I+PGF1dGhvcj5MaSwgSHVpPC9hdXRob3I+PGF1dGhvcj5XdSwgWHVkb25nPC9hdXRob3I+PGF1 dGhvcj5YdSwgSml1eWFuZzwvYXV0aG9yPjxhdXRob3I+VHUsIFNoZW5namluPC9hdXRob3I+PGF1 dGhvcj5aaGFuZywgWWk8L2F1dGhvcj48YXV0aG9yPkNoZW4sIEh1YTwvYXV0aG9yPjxhdXRob3I+ Q2FvLCBCaW48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5E ZXBhcnRtZW50IG9mIFB1bG1vbmFyeSBhbmQgQ3JpdGljYWwgQ2FyZSBNZWRpY2luZSwgQ2VudGVy IG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBDZW50 ZXIgZm9yIFJlc3BpcmF0b3J5IERpc2Vhc2VzLCBJbnN0aXR1dGUgb2YgUmVzcGlyYXRvcnkgTWVk aWNpbmUsIENoaW5lc2UgQWNhZGVteSBvZiBNZWRpY2FsIFNjaWVuY2VzLCBQZWtpbmcgVW5pb24g TWVkaWNhbCBDb2xsZWdlLCBCZWlqaW5nLCBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0 aXRsZT5DbGluaWNhbCBjb3Vyc2UgYW5kIHJpc2sgZmFjdG9ycyBmb3IgbW9ydGFsaXR5IG9mIGFk dWx0IGlucGF0aWVudHMgd2l0aCBDT1ZJRC0xOSBpbiBXdWhhbiwgQ2hpbmE6IGEgcmV0cm9zcGVj dGl2ZSBjb2hvcnQgc3R1ZHk8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+TGFuY2V0IChMb25kb24s IEVuZ2xhbmQpPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5MYW5jZXQ8L2FsdC10aXRsZT48 L3RpdGxlcz48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TGFuY2V0PC9mdWxsLXRpdGxlPjwv YWx0LXBlcmlvZGljYWw+PHBhZ2VzPjEwNTQtMTA2MjwvcGFnZXM+PHZvbHVtZT4zOTU8L3ZvbHVt ZT48bnVtYmVyPjEwMjI5PC9udW1iZXI+PGtleXdvcmRzPjxrZXl3b3JkPlJpc2sgQXNzZXNzbWVu dDwva2V5d29yZD48a2V5d29yZD5QYXRpZW50IENhcmUgUGxhbm5pbmc8L2tleXdvcmQ+PGtleXdv cmQ+T3JnYW4gRHlzZnVuY3Rpb24gU2NvcmVzPC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5 ZWFyPjIwMjA8L3llYXI+PHB1Yi1kYXRlcz48ZGF0ZT4yMDIwLzAzLy88L2RhdGU+PC9wdWItZGF0 ZXM+PC9kYXRlcz48aXNibj4wMTQwLTY3MzY8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIxNzEwNzY8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJsPmh0dHA6Ly9ldXJvcGVwbWMu b3JnL2Fic3RyYWN0L01FRC8zMjE3MTA3NjwvdXJsPjx1cmw+aHR0cHM6Ly9kb2kub3JnLzEwLjEw MTYvUzAxNDAtNjczNigyMCkzMDU2Ni0zPC91cmw+PHVybD5odHRwczovL2V1cm9wZXBtYy5vcmcv YXJ0aWNsZXMvUE1DNzI3MDYyNzwvdXJsPjwvcmVsYXRlZC11cmxzPjwvdXJscz48ZWxlY3Ryb25p Yy1yZXNvdXJjZS1udW0+MTAuMTAxNi9zMDE0MC02NzM2KDIwKTMwNTY2LTM8L2VsZWN0cm9uaWMt cmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtbmFtZT5QdWJNZWQ8L3JlbW90ZS1kYXRhYmFz ZS1uYW1lPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE.DATA (12)، بیماری کلیوی ADDIN EN.CITE <EndNote><Cite><Author>Cheng</Author><Year>2020</Year><RecNum>129</RecNum><DisplayText>(13)</DisplayText><record><rec-number>129</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">129</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Cheng, Yichun</author><author>Luo, Ran</author><author>Wang, Kun</author><author>Zhang, Meng</author><author>Wang, Zhixiang</author><author>Dong, Lei</author><author>Li, Junhua</author><author>Yao, Ying</author><author>Ge, Shuwang</author><author>Xu, Gang</author></authors></contributors><titles><title>Kidney impairment is associated with in-hospital death of COVID-19 patients</title><secondary-title>MedRxiv</secondary-title></titles><periodical><full-title>medRxiv</full-title></periodical><dates><year>2020</year></dates><urls></urls></record></Cite></EndNote>(13)، دیابت یا سابقه ابتلا به بدخیمی و بیماریهای ایسکمیک مغزی، در مبتلایان، نسبت به سایر مبتلایان بدون بیماری زمینهای، با افزایش میزان مرگ و میر، همراه بوده ‌است ADDIN EN.CITE <EndNote><Cite><Author>Onder</Author><Year>2020</Year><RecNum>68</RecNum><DisplayText>(14)</DisplayText><record><rec-number>68</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">68</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Onder, Graziano</author><author>Rezza, Giovanni</author><author>Brusaferro, Silvio</author></authors></contributors><titles><title>Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy</title><secondary-title>JAMA</secondary-title></titles><periodical><full-title>Jama</full-title></periodical><dates><year>2020</year></dates><urls></urls></record></Cite></EndNote>(14).ناهنجاریهای آزمایشگاهی مشابه مواردی است که قبلاً در بیماران مبتلا به مرس و سارس مشاهده شده بود PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE.DATA (9). به طوری‌که، بیماران ممکن است شمارش گلبولهای خون نرمال یا پایین، لنفوپنی یا ترومبوسیتوپنی را نشان دهند، همچنین طولانی شدن زمان ترومبوپلاستین و افزایش پروتئین واکنشی فاز حاد

C-reactive protein (CRP) نیز ممکن است بروز نماید. این درحالی است که افزایش سطح آنزیم لاکتات دهیدروژناز

LDH و افزایش سطح برخی آنزیمهای کبدی از جمله آسپارات تراسفراز

AST و آلانین ترانسفراز

ALT نیز گزارش شده‌است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5GYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+NTc8L1JlY051bT48RGlzcGxheVRleHQ+KDE1KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj41NzwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTc8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPkZhbiwgWi48L2F1dGhvcj48YXV0aG9yPkNoZW4sIEwu PC9hdXRob3I+PGF1dGhvcj5MaSwgSi48L2F1dGhvcj48YXV0aG9yPkNoZW5nLCBYLjwvYXV0aG9y PjxhdXRob3I+WWFuZywgSi48L2F1dGhvcj48YXV0aG9yPlRpYW4sIEMuPC9hdXRob3I+PGF1dGhv cj5aaGFuZywgWS48L2F1dGhvcj48YXV0aG9yPkh1YW5nLCBTLjwvYXV0aG9yPjxhdXRob3I+TGl1 LCBaLjwvYXV0aG9yPjxhdXRob3I+Q2hlbmcsIEouPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJp YnV0b3JzPjxhdXRoLWFkZHJlc3M+RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRlcm9sb2d5IGFuZCBI ZXBhdG9sb2d5LCBTaGFuZ2hhaSBQdWJsaWMgSGVhbHRoIENsaW5pY2FsIENlbnRlciwgRnVkYW4g VW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRl cm9sb2d5LCBUaGUgU2hhbmdoYWkgVGVudGggUGVvcGxlJmFwb3M7cyBIb3NwaXRhbCBvZiBUb25n amkgVW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiBFbGVjdHJvbmljIGFkZHJlc3M6IGxpdXpo YW5qdTg4QDEyNi5jb20uJiN4RDtEZXBhcnRtZW50IG9mIEdhc3Ryb2VudGVyb2xvZ3kgYW5kIEhl cGF0b2xvZ3ksIFNoYW5naGFpIFB1YmxpYyBIZWFsdGggQ2xpbmljYWwgQ2VudGVyLCBGdWRhbiBV bml2ZXJzaXR5LCBTaGFuZ2hhaSwgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2hlbmdqaWxp bkBzaHBoYy5vcmcuY24uPC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+Q2xpbmljYWwgRmVh dHVyZXMgb2YgQ09WSUQtMTktUmVsYXRlZCBMaXZlciBGdW5jdGlvbmFsIEFibm9ybWFsaXR5PC90 aXRsZT48c2Vjb25kYXJ5LXRpdGxlPkNsaW4gR2FzdHJvZW50ZXJvbCBIZXBhdG9sPC9zZWNvbmRh cnktdGl0bGU+PGFsdC10aXRsZT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9s b2d5IDogdGhlIG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJp Y2FuIEdhc3Ryb2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FsdC10aXRsZT48L3RpdGxlcz48 cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5DbGluIEdhc3Ryb2VudGVyb2wgSGVwYXRvbDwvZnVsbC10 aXRsZT48YWJici0xPkNsaW5pY2FsIGdhc3Ryb2VudGVyb2xvZ3kgYW5kIGhlcGF0b2xvZ3kgOiB0 aGUgb2ZmaWNpYWwgY2xpbmljYWwgcHJhY3RpY2Ugam91cm5hbCBvZiB0aGUgQW1lcmljYW4gR2Fz dHJvZW50ZXJvbG9naWNhbCBBc3NvY2lhdGlvbjwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBl cmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2xpbiBHYXN0cm9lbnRlcm9sIEhlcGF0b2w8L2Z1bGwtdGl0 bGU+PGFiYnItMT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9sb2d5IDogdGhl IG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJpY2FuIEdhc3Ry b2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdl cz4xNTYxLTE1NjY8L3BhZ2VzPjx2b2x1bWU+MTg8L3ZvbHVtZT48bnVtYmVyPjc8L251bWJlcj48 ZWRpdGlvbj4yMDIwLzA0LzE0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5 d29yZD48a2V5d29yZD5BbnRpdmlyYWwgQWdlbnRzL3RoZXJhcGV1dGljIHVzZTwva2V5d29yZD48 a2V5d29yZD5CZXRhY29yb25hdmlydXMvKmlzb2xhdGlvbiAmYW1wOyBwdXJpZmljYXRpb248L2tl eXdvcmQ+PGtleXdvcmQ+QmlsaXJ1YmluL2Jsb29kPC9rZXl3b3JkPjxrZXl3b3JkPkJsb29kIENo ZW1pY2FsIEFuYWx5c2lzPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwva2V5 d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZlY3Rpb25zLypjb21wbGljYXRpb25zLypwYXRo b2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+RW56eW1lcy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5G ZW1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+SG9zcGl0YWxzPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFu czwva2V5d29yZD48a2V5d29yZD5MaXZlciBEaXNlYXNlcy9kcnVnIHRoZXJhcHkvKmVwaWRlbWlv bG9neS8qZXRpb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+KkxpdmVyIEZ1bmN0aW9uIFRlc3RzPC9r ZXl3b3JkPjxrZXl3b3JkPkxvcGluYXZpci90aGVyYXBldXRpYyB1c2U8L2tleXdvcmQ+PGtleXdv cmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29yZD5Q YW5kZW1pY3M8L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC8qY29tcGxpY2F0aW9u cy8qcGF0aG9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPlByZXZhbGVuY2U8L2tleXdvcmQ+PGtleXdv cmQ+UmV0cm9zcGVjdGl2ZSBTdHVkaWVzPC9rZXl3b3JkPjxrZXl3b3JkPlJpdG9uYXZpci90aGVy YXBldXRpYyB1c2U8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48 cHViLWRhdGVzPjxkYXRlPkp1bjwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjE1NDIt MzU2NSAoUHJpbnQpJiN4RDsxNTQyLTM1NjU8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIyODMzMjU8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0b20yPlBtYzcxOTQ4NjU8L2N1c3RvbTI+ PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwMTYvai5jZ2guMjAyMC4wNC4wMDI8L2VsZWN0 cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1vdGUt ZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9DaXRl PjwvRW5kTm90ZT5= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5GYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+NTc8L1JlY051bT48RGlzcGxheVRleHQ+KDE1KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj41NzwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTc8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPkZhbiwgWi48L2F1dGhvcj48YXV0aG9yPkNoZW4sIEwu PC9hdXRob3I+PGF1dGhvcj5MaSwgSi48L2F1dGhvcj48YXV0aG9yPkNoZW5nLCBYLjwvYXV0aG9y PjxhdXRob3I+WWFuZywgSi48L2F1dGhvcj48YXV0aG9yPlRpYW4sIEMuPC9hdXRob3I+PGF1dGhv cj5aaGFuZywgWS48L2F1dGhvcj48YXV0aG9yPkh1YW5nLCBTLjwvYXV0aG9yPjxhdXRob3I+TGl1 LCBaLjwvYXV0aG9yPjxhdXRob3I+Q2hlbmcsIEouPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJp YnV0b3JzPjxhdXRoLWFkZHJlc3M+RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRlcm9sb2d5IGFuZCBI ZXBhdG9sb2d5LCBTaGFuZ2hhaSBQdWJsaWMgSGVhbHRoIENsaW5pY2FsIENlbnRlciwgRnVkYW4g VW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRl cm9sb2d5LCBUaGUgU2hhbmdoYWkgVGVudGggUGVvcGxlJmFwb3M7cyBIb3NwaXRhbCBvZiBUb25n amkgVW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiBFbGVjdHJvbmljIGFkZHJlc3M6IGxpdXpo YW5qdTg4QDEyNi5jb20uJiN4RDtEZXBhcnRtZW50IG9mIEdhc3Ryb2VudGVyb2xvZ3kgYW5kIEhl cGF0b2xvZ3ksIFNoYW5naGFpIFB1YmxpYyBIZWFsdGggQ2xpbmljYWwgQ2VudGVyLCBGdWRhbiBV bml2ZXJzaXR5LCBTaGFuZ2hhaSwgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2hlbmdqaWxp bkBzaHBoYy5vcmcuY24uPC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+Q2xpbmljYWwgRmVh dHVyZXMgb2YgQ09WSUQtMTktUmVsYXRlZCBMaXZlciBGdW5jdGlvbmFsIEFibm9ybWFsaXR5PC90 aXRsZT48c2Vjb25kYXJ5LXRpdGxlPkNsaW4gR2FzdHJvZW50ZXJvbCBIZXBhdG9sPC9zZWNvbmRh cnktdGl0bGU+PGFsdC10aXRsZT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9s b2d5IDogdGhlIG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJp Y2FuIEdhc3Ryb2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FsdC10aXRsZT48L3RpdGxlcz48 cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5DbGluIEdhc3Ryb2VudGVyb2wgSGVwYXRvbDwvZnVsbC10 aXRsZT48YWJici0xPkNsaW5pY2FsIGdhc3Ryb2VudGVyb2xvZ3kgYW5kIGhlcGF0b2xvZ3kgOiB0 aGUgb2ZmaWNpYWwgY2xpbmljYWwgcHJhY3RpY2Ugam91cm5hbCBvZiB0aGUgQW1lcmljYW4gR2Fz dHJvZW50ZXJvbG9naWNhbCBBc3NvY2lhdGlvbjwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBl cmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2xpbiBHYXN0cm9lbnRlcm9sIEhlcGF0b2w8L2Z1bGwtdGl0 bGU+PGFiYnItMT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9sb2d5IDogdGhl IG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJpY2FuIEdhc3Ry b2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdl cz4xNTYxLTE1NjY8L3BhZ2VzPjx2b2x1bWU+MTg8L3ZvbHVtZT48bnVtYmVyPjc8L251bWJlcj48 ZWRpdGlvbj4yMDIwLzA0LzE0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5 d29yZD48a2V5d29yZD5BbnRpdmlyYWwgQWdlbnRzL3RoZXJhcGV1dGljIHVzZTwva2V5d29yZD48 a2V5d29yZD5CZXRhY29yb25hdmlydXMvKmlzb2xhdGlvbiAmYW1wOyBwdXJpZmljYXRpb248L2tl eXdvcmQ+PGtleXdvcmQ+QmlsaXJ1YmluL2Jsb29kPC9rZXl3b3JkPjxrZXl3b3JkPkJsb29kIENo ZW1pY2FsIEFuYWx5c2lzPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwva2V5 d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZlY3Rpb25zLypjb21wbGljYXRpb25zLypwYXRo b2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+RW56eW1lcy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5G ZW1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+SG9zcGl0YWxzPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFu czwva2V5d29yZD48a2V5d29yZD5MaXZlciBEaXNlYXNlcy9kcnVnIHRoZXJhcHkvKmVwaWRlbWlv bG9neS8qZXRpb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+KkxpdmVyIEZ1bmN0aW9uIFRlc3RzPC9r ZXl3b3JkPjxrZXl3b3JkPkxvcGluYXZpci90aGVyYXBldXRpYyB1c2U8L2tleXdvcmQ+PGtleXdv cmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29yZD5Q YW5kZW1pY3M8L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC8qY29tcGxpY2F0aW9u cy8qcGF0aG9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPlByZXZhbGVuY2U8L2tleXdvcmQ+PGtleXdv cmQ+UmV0cm9zcGVjdGl2ZSBTdHVkaWVzPC9rZXl3b3JkPjxrZXl3b3JkPlJpdG9uYXZpci90aGVy YXBldXRpYyB1c2U8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48 cHViLWRhdGVzPjxkYXRlPkp1bjwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjE1NDIt MzU2NSAoUHJpbnQpJiN4RDsxNTQyLTM1NjU8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIyODMzMjU8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0b20yPlBtYzcxOTQ4NjU8L2N1c3RvbTI+ PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwMTYvai5jZ2guMjAyMC4wNC4wMDI8L2VsZWN0 cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1vdGUt ZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9DaXRl PjwvRW5kTm90ZT5= ADDIN EN.CITE.DATA (15). به علاوه، احتمال افزایش سطح اوره و کراتنین PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE.DATA (9)، و سطح دی-دایمر

D-Dimer نیز در این بیماران، بسیار زیاد بوده ADDIN EN.CITE <EndNote><Cite><Author>Qiu</Author><Year>2020</Year><RecNum>109</RecNum><DisplayText>(16)</DisplayText><record><rec-number>109</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">109</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Qiu, Haiyan</author><author>Wu, Junhua</author><author>Hong, Liang</author><author>Luo, Yunling</author><author>Song, Qifa</author><author>Chen, Dong</author></authors></contributors><titles><title>Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study</title><secondary-title>The Lancet Infectious Diseases</secondary-title></titles><periodical><full-title>The Lancet Infectious Diseases</full-title></periodical><dates><year>2020</year><pub-dates><date>2020/03/25/</date></pub-dates></dates><isbn>1473-3099</isbn><urls><related-urls><url>http://www.sciencedirect.com/science/article/pii/S1473309920301985</url></related-urls></urls><electronic-resource-num>https://doi.org/10.1016/S1473-3099(20)30198-5</electronic-resource-num></record></Cite></EndNote>(16) و همچنین در بسیاری از بیماران سرعت رسوب گلبولهای قرمز

ESR نیز بالا بوده ‌است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5TdW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+NTI8L1JlY051bT48RGlzcGxheVRleHQ+KDE3KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj41MjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTI8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlN1biwgWWluZzwvYXV0aG9yPjxhdXRob3I+RG9uZywg WWFubGk8L2F1dGhvcj48YXV0aG9yPldhbmcsIExpZmVuZzwvYXV0aG9yPjxhdXRob3I+WGllLCBI dWFuPC9hdXRob3I+PGF1dGhvcj5MaSwgQmFvc2VuPC9hdXRob3I+PGF1dGhvcj5DaGFuZywgQ2hy aXN0b3BoZXI8L2F1dGhvcj48YXV0aG9yPldhbmcsIEZ1LVNoZW5nPC9hdXRob3I+PC9hdXRob3Jz PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkNoYXJhY3RlcmlzdGljcyBhbmQgcHJvZ25v c3RpYyBmYWN0b3JzIG9mIGRpc2Vhc2Ugc2V2ZXJpdHkgaW4gcGF0aWVudHMgd2l0aCBDT1ZJRC0x OTogVGhlIEJlaWppbmcgZXhwZXJpZW5jZTwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5Kb3VybmFs IG9mIGF1dG9pbW11bml0eTwvc2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+SiBBdXRvaW1tdW48 L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5Kb3VybmFsIG9mIGF1 dG9pbW11bml0eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0b2ltbXVuPC9hYmJyLTE+PC9wZXJp b2RpY2FsPjxhbHQtcGVyaW9kaWNhbD48ZnVsbC10aXRsZT5Kb3VybmFsIG9mIGF1dG9pbW11bml0 eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0b2ltbXVuPC9hYmJyLTE+PC9hbHQtcGVyaW9kaWNh bD48cGFnZXM+MTAyNDczLTEwMjQ3MzwvcGFnZXM+PHZvbHVtZT4xMTI8L3ZvbHVtZT48ZWRpdGlv bj4wNC8yNDwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KjIwMTkgbm92ZWwgY29yb25hdmly dXMgZGlzZWFzZTwva2V5d29yZD48a2V5d29yZD4qQ09WSUQtMTk8L2tleXdvcmQ+PGtleXdvcmQ+ KkN5dG9raW5lIHN0b3JtPC9rZXl3b3JkPjxrZXl3b3JkPipFbGV2YXRlZCBsaXZlciBlbnp5bWVz PC9rZXl3b3JkPjxrZXl3b3JkPipJbnRlcmxldWtpbi02PC9rZXl3b3JkPjxrZXl3b3JkPipMeW1w aG9jeXRlIHN1YnNldHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk1vcnRhbGl0eTwva2V5d29yZD48a2V5 d29yZD4qUHJvZ25vc2lzPC9rZXl3b3JkPjxrZXl3b3JkPipTQVJTLUNvVi0yPC9rZXl3b3JkPjxr ZXl3b3JkPkFkb2xlc2NlbnQ8L2tleXdvcmQ+PGtleXdvcmQ+QWR1bHQ8L2tleXdvcmQ+PGtleXdv cmQ+QWdlZDwva2V5d29yZD48a2V5d29yZD5BZ2VkLCA4MCBhbmQgb3Zlcjwva2V5d29yZD48a2V5 d29yZD5CZXRhY29yb25hdmlydXMvKm1ldGFib2xpc208L2tleXdvcmQ+PGtleXdvcmQ+QmlvbWFy a2Vycy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5DaGlsZDwva2V5d29yZD48a2V5d29yZD5DaGls ZCwgUHJlc2Nob29sPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwva2V5d29y ZD48a2V5d29yZD4qQ29yb25hdmlydXMgSW5mZWN0aW9ucy9ibG9vZC9lcGlkZW1pb2xvZ3k8L2tl eXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48 a2V5d29yZD5MZXVrb2N5dGUgQ291bnQ8L2tleXdvcmQ+PGtleXdvcmQ+TWFsZTwva2V5d29yZD48 a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29yZD4qUGFuZGVtaWNzPC9rZXl3b3Jk PjxrZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2Jsb29kL2VwaWRlbWlvbG9neTwva2V5d29yZD48 a2V5d29yZD4qU2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48a2V5d29yZD5TZXgg RmFjdG9yczwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjwvZGF0 ZXM+PHB1Ymxpc2hlcj5QdWJsaXNoZWQgYnkgRWxzZXZpZXIgTHRkLjwvcHVibGlzaGVyPjxpc2Ju PjEwOTUtOTE1NyYjeEQ7MDg5Ni04NDExPC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMyNDM5MjA5PC9h Y2Nlc3Npb24tbnVtPjx1cmxzPjxyZWxhdGVkLXVybHM+PHVybD5odHRwczovL3B1Ym1lZC5uY2Jp Lm5sbS5uaWguZ292LzMyNDM5MjA5PC91cmw+PHVybD5odHRwczovL3d3dy5uY2JpLm5sbS5uaWgu Z292L3BtYy9hcnRpY2xlcy9QTUM3MTgwMzc2LzwvdXJsPjwvcmVsYXRlZC11cmxzPjwvdXJscz48 ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9qLmphdXQuMjAyMC4xMDI0NzM8L2VsZWN0 cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtbmFtZT5QdWJNZWQ8L3JlbW90ZS1k YXRhYmFzZS1uYW1lPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0Vu ZE5vdGU+ ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5TdW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+NTI8L1JlY051bT48RGlzcGxheVRleHQ+KDE3KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj41MjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTI8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlN1biwgWWluZzwvYXV0aG9yPjxhdXRob3I+RG9uZywg WWFubGk8L2F1dGhvcj48YXV0aG9yPldhbmcsIExpZmVuZzwvYXV0aG9yPjxhdXRob3I+WGllLCBI dWFuPC9hdXRob3I+PGF1dGhvcj5MaSwgQmFvc2VuPC9hdXRob3I+PGF1dGhvcj5DaGFuZywgQ2hy aXN0b3BoZXI8L2F1dGhvcj48YXV0aG9yPldhbmcsIEZ1LVNoZW5nPC9hdXRob3I+PC9hdXRob3Jz PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkNoYXJhY3RlcmlzdGljcyBhbmQgcHJvZ25v c3RpYyBmYWN0b3JzIG9mIGRpc2Vhc2Ugc2V2ZXJpdHkgaW4gcGF0aWVudHMgd2l0aCBDT1ZJRC0x OTogVGhlIEJlaWppbmcgZXhwZXJpZW5jZTwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5Kb3VybmFs IG9mIGF1dG9pbW11bml0eTwvc2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+SiBBdXRvaW1tdW48 L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5Kb3VybmFsIG9mIGF1 dG9pbW11bml0eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0b2ltbXVuPC9hYmJyLTE+PC9wZXJp b2RpY2FsPjxhbHQtcGVyaW9kaWNhbD48ZnVsbC10aXRsZT5Kb3VybmFsIG9mIGF1dG9pbW11bml0 eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0b2ltbXVuPC9hYmJyLTE+PC9hbHQtcGVyaW9kaWNh bD48cGFnZXM+MTAyNDczLTEwMjQ3MzwvcGFnZXM+PHZvbHVtZT4xMTI8L3ZvbHVtZT48ZWRpdGlv bj4wNC8yNDwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KjIwMTkgbm92ZWwgY29yb25hdmly dXMgZGlzZWFzZTwva2V5d29yZD48a2V5d29yZD4qQ09WSUQtMTk8L2tleXdvcmQ+PGtleXdvcmQ+ KkN5dG9raW5lIHN0b3JtPC9rZXl3b3JkPjxrZXl3b3JkPipFbGV2YXRlZCBsaXZlciBlbnp5bWVz PC9rZXl3b3JkPjxrZXl3b3JkPipJbnRlcmxldWtpbi02PC9rZXl3b3JkPjxrZXl3b3JkPipMeW1w aG9jeXRlIHN1YnNldHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk1vcnRhbGl0eTwva2V5d29yZD48a2V5 d29yZD4qUHJvZ25vc2lzPC9rZXl3b3JkPjxrZXl3b3JkPipTQVJTLUNvVi0yPC9rZXl3b3JkPjxr ZXl3b3JkPkFkb2xlc2NlbnQ8L2tleXdvcmQ+PGtleXdvcmQ+QWR1bHQ8L2tleXdvcmQ+PGtleXdv cmQ+QWdlZDwva2V5d29yZD48a2V5d29yZD5BZ2VkLCA4MCBhbmQgb3Zlcjwva2V5d29yZD48a2V5 d29yZD5CZXRhY29yb25hdmlydXMvKm1ldGFib2xpc208L2tleXdvcmQ+PGtleXdvcmQ+QmlvbWFy a2Vycy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5DaGlsZDwva2V5d29yZD48a2V5d29yZD5DaGls ZCwgUHJlc2Nob29sPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwva2V5d29y ZD48a2V5d29yZD4qQ29yb25hdmlydXMgSW5mZWN0aW9ucy9ibG9vZC9lcGlkZW1pb2xvZ3k8L2tl eXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48 a2V5d29yZD5MZXVrb2N5dGUgQ291bnQ8L2tleXdvcmQ+PGtleXdvcmQ+TWFsZTwva2V5d29yZD48 a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29yZD4qUGFuZGVtaWNzPC9rZXl3b3Jk PjxrZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2Jsb29kL2VwaWRlbWlvbG9neTwva2V5d29yZD48 a2V5d29yZD4qU2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48a2V5d29yZD5TZXgg RmFjdG9yczwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjwvZGF0 ZXM+PHB1Ymxpc2hlcj5QdWJsaXNoZWQgYnkgRWxzZXZpZXIgTHRkLjwvcHVibGlzaGVyPjxpc2Ju PjEwOTUtOTE1NyYjeEQ7MDg5Ni04NDExPC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMyNDM5MjA5PC9h Y2Nlc3Npb24tbnVtPjx1cmxzPjxyZWxhdGVkLXVybHM+PHVybD5odHRwczovL3B1Ym1lZC5uY2Jp Lm5sbS5uaWguZ292LzMyNDM5MjA5PC91cmw+PHVybD5odHRwczovL3d3dy5uY2JpLm5sbS5uaWgu Z292L3BtYy9hcnRpY2xlcy9QTUM3MTgwMzc2LzwvdXJsPjwvcmVsYXRlZC11cmxzPjwvdXJscz48 ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9qLmphdXQuMjAyMC4xMDI0NzM8L2VsZWN0 cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtbmFtZT5QdWJNZWQ8L3JlbW90ZS1k YXRhYmFzZS1uYW1lPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0Vu ZE5vdGU+ ADDIN EN.CITE.DATA (17). از نظر علائم رادیولوژیکی نیز ویژگیهای تصویربرداری در سیتیاسکن ریه مبتلایان به کووید-19 میتواند در غربالگری اولیه موارد مشکوک و نیز در ارزیابی شدت و میزان بیماری مفید باشند PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaGFvPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY3PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxOCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+Njc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjY3PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaGFvLCBXLjwvYXV0aG9yPjxhdXRob3I+Wmhvbmcs IFouPC9hdXRob3I+PGF1dGhvcj5YaWUsIFguPC9hdXRob3I+PGF1dGhvcj5ZdSwgUS48L2F1dGhv cj48YXV0aG9yPkxpdSwgSi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgt YWRkcmVzcz5EZXBhcnRtZW50IG9mIFJhZGlvbG9neSwgVGhlIFNlY29uZCBYaWFuZ3lhIEhvc3Bp dGFsLCBDZW50cmFsIFNvdXRoIFVuaXZlcnNpdHksIE5vLiAxMzkgTWlkZGxlIFJlbWluIFJkLCBD aGFuZ3NoYSwgSHVuYW4sIDQxMDAxMSwgUC5SLiBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUmFk aW9sb2d5LCBGaXJzdCBIb3NwaXRhbCBvZiBDaGFuZ3NoYSwgSHVuYW4sIFAuUi4gQ2hpbmEuJiN4 RDtDaGFuZ3NoYSBQdWJsaWMgSGVhbHRoIFRyZWF0bWVudCBDZW50ZXIsIEh1bmFuLCBQLlIuIENo aW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSYWRpb2xvZ3ksIFF1YWxpdHkgQ29udHJvbCBDZW50ZXIs IENoYW5nc2hhLCBIdW5hbiwgUC5SLiBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRs ZT5SZWxhdGlvbiBCZXR3ZWVuIENoZXN0IENUIEZpbmRpbmdzIGFuZCBDbGluaWNhbCBDb25kaXRp b25zIG9mIENvcm9uYXZpcnVzIERpc2Vhc2UgKENPVklELTE5KSBQbmV1bW9uaWE6IEEgTXVsdGlj ZW50ZXIgU3R1ZHk8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+QUpSIEFtIEogUm9lbnRnZW5vbDwv c2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+QUpSLiBBbWVyaWNhbiBqb3VybmFsIG9mIHJvZW50 Z2Vub2xvZ3k8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5BSlIg QW0gSiBSb2VudGdlbm9sPC9mdWxsLXRpdGxlPjxhYmJyLTE+QUpSLiBBbWVyaWNhbiBqb3VybmFs IG9mIHJvZW50Z2Vub2xvZ3k8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkFKUiBBbSBKIFJvZW50Z2Vub2w8L2Z1bGwtdGl0bGU+PGFiYnItMT5BSlIuIEFt ZXJpY2FuIGpvdXJuYWwgb2Ygcm9lbnRnZW5vbG9neTwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+ PHBhZ2VzPjEwNzItMTA3NzwvcGFnZXM+PHZvbHVtZT4yMTQ8L3ZvbHVtZT48bnVtYmVyPjU8L251 bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzA0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZG9s ZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tl eXdvcmQ+PGtleXdvcmQ+KkJldGFjb3JvbmF2aXJ1czwva2V5d29yZD48a2V5d29yZD5Db3JvbmF2 aXJ1cyBJbmZlY3Rpb25zLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3 b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3 b3JkPk1pZGRsZSBBZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPlBhbmRlbWljczwva2V5d29yZD48a2V5 d29yZD5QbmV1bW9uaWEsIFZpcmFsLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+U2V2ZXJp dHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48a2V5d29yZD4qVG9tb2dyYXBoeSwgWC1SYXkg Q29tcHV0ZWQ8L2tleXdvcmQ+PGtleXdvcmQ+WW91bmcgQWR1bHQ8L2tleXdvcmQ+PC9rZXl3b3Jk cz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48cHViLWRhdGVzPjxkYXRlPk1heTwvZGF0ZT48L3B1 Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjAzNjEtODAzeDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjEy NTg3MzwvYWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVt PjEwLjIyMTQvYWpyLjIwLjIyOTc2PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRh dGFiYXNlLXByb3ZpZGVyPk5sbTwvcmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxsYW5ndWFnZT5l bmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaGFvPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY3PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxOCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+Njc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjY3PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaGFvLCBXLjwvYXV0aG9yPjxhdXRob3I+Wmhvbmcs IFouPC9hdXRob3I+PGF1dGhvcj5YaWUsIFguPC9hdXRob3I+PGF1dGhvcj5ZdSwgUS48L2F1dGhv cj48YXV0aG9yPkxpdSwgSi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgt YWRkcmVzcz5EZXBhcnRtZW50IG9mIFJhZGlvbG9neSwgVGhlIFNlY29uZCBYaWFuZ3lhIEhvc3Bp dGFsLCBDZW50cmFsIFNvdXRoIFVuaXZlcnNpdHksIE5vLiAxMzkgTWlkZGxlIFJlbWluIFJkLCBD aGFuZ3NoYSwgSHVuYW4sIDQxMDAxMSwgUC5SLiBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUmFk aW9sb2d5LCBGaXJzdCBIb3NwaXRhbCBvZiBDaGFuZ3NoYSwgSHVuYW4sIFAuUi4gQ2hpbmEuJiN4 RDtDaGFuZ3NoYSBQdWJsaWMgSGVhbHRoIFRyZWF0bWVudCBDZW50ZXIsIEh1bmFuLCBQLlIuIENo aW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSYWRpb2xvZ3ksIFF1YWxpdHkgQ29udHJvbCBDZW50ZXIs IENoYW5nc2hhLCBIdW5hbiwgUC5SLiBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRs ZT5SZWxhdGlvbiBCZXR3ZWVuIENoZXN0IENUIEZpbmRpbmdzIGFuZCBDbGluaWNhbCBDb25kaXRp b25zIG9mIENvcm9uYXZpcnVzIERpc2Vhc2UgKENPVklELTE5KSBQbmV1bW9uaWE6IEEgTXVsdGlj ZW50ZXIgU3R1ZHk8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+QUpSIEFtIEogUm9lbnRnZW5vbDwv c2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+QUpSLiBBbWVyaWNhbiBqb3VybmFsIG9mIHJvZW50 Z2Vub2xvZ3k8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5BSlIg QW0gSiBSb2VudGdlbm9sPC9mdWxsLXRpdGxlPjxhYmJyLTE+QUpSLiBBbWVyaWNhbiBqb3VybmFs IG9mIHJvZW50Z2Vub2xvZ3k8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkFKUiBBbSBKIFJvZW50Z2Vub2w8L2Z1bGwtdGl0bGU+PGFiYnItMT5BSlIuIEFt ZXJpY2FuIGpvdXJuYWwgb2Ygcm9lbnRnZW5vbG9neTwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+ PHBhZ2VzPjEwNzItMTA3NzwvcGFnZXM+PHZvbHVtZT4yMTQ8L3ZvbHVtZT48bnVtYmVyPjU8L251 bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzA0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZG9s ZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tl eXdvcmQ+PGtleXdvcmQ+KkJldGFjb3JvbmF2aXJ1czwva2V5d29yZD48a2V5d29yZD5Db3JvbmF2 aXJ1cyBJbmZlY3Rpb25zLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3 b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3 b3JkPk1pZGRsZSBBZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPlBhbmRlbWljczwva2V5d29yZD48a2V5 d29yZD5QbmV1bW9uaWEsIFZpcmFsLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+U2V2ZXJp dHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48a2V5d29yZD4qVG9tb2dyYXBoeSwgWC1SYXkg Q29tcHV0ZWQ8L2tleXdvcmQ+PGtleXdvcmQ+WW91bmcgQWR1bHQ8L2tleXdvcmQ+PC9rZXl3b3Jk cz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48cHViLWRhdGVzPjxkYXRlPk1heTwvZGF0ZT48L3B1 Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjAzNjEtODAzeDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjEy NTg3MzwvYWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVt PjEwLjIyMTQvYWpyLjIwLjIyOTc2PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRh dGFiYXNlLXByb3ZpZGVyPk5sbTwvcmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxsYW5ndWFnZT5l bmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE.DATA (18).براساس نتایج مطالعات، درگیری دوطرفه ریه با الگوی گراندگلاس، رایجترین یافته در تصاویر توموگرافی کامپیوتری از قفسهسینهی این بیماران بوده‌است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5XYW5nPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY2PC9SZWNOdW0+PERpc3BsYXlUZXh0Pig5KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj42NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NjY8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPldhbmcsIFlpeHVhbjwvYXV0aG9yPjxhdXRob3I+V2Fu ZywgWXV5aTwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgWWFuPC9hdXRob3I+PGF1dGhvcj5RaW4sIFFp bmdzb25nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlVu aXF1ZSBlcGlkZW1pb2xvZ2ljYWwgYW5kIGNsaW5pY2FsIGZlYXR1cmVzIG9mIHRoZSBlbWVyZ2lu ZyAyMDE5IG5vdmVsIGNvcm9uYXZpcnVzIHBuZXVtb25pYSAoQ09WSUQtMTkpIGltcGxpY2F0ZSBz cGVjaWFsIGNvbnRyb2wgbWVhc3VyZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Sm91cm5hbCBv ZiBtZWRpY2FsIHZpcm9sb2d5PC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5KIE1lZCBWaXJv bDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkpvdXJuYWwgb2Yg TWVkaWNhbCBWaXJvbG9neTwvZnVsbC10aXRsZT48L3BlcmlvZGljYWw+PHBhZ2VzPjU2OC01NzY8 L3BhZ2VzPjx2b2x1bWU+OTI8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4wMy8y OTwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+KkNPVklELTE5PC9rZXl3b3JkPjxrZXl3b3Jk PipkaWFnbm9zaXMgYW5kIGludGVydmVudGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+KmZlYXR1cmVz PC9rZXl3b3JkPjxrZXl3b3JkPkFudGl2aXJhbCBBZ2VudHMvdGhlcmFwZXV0aWMgdXNlPC9rZXl3 b3JkPjxrZXl3b3JkPkJldGFjb3JvbmF2aXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5pY2l0eTwv a2V5d29yZD48a2V5d29yZD5DaGluYS9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+Q29t bXVuaWNhYmxlIERpc2Vhc2UgQ29udHJvbC8qb3JnYW5pemF0aW9uICZhbXA7IGFkbWluaXN0cmF0 aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvZHJ1ZyB0aGVyYXB5 LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RoZXJhcHkvdHJhbnNtaXNz aW9uPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5JbW11bml6YXRp b24sIFBhc3NpdmUvbWV0aG9kczwva2V5d29yZD48a2V5d29yZD5MeW1waG9wZW5pYS9waHlzaW9w YXRob2xvZ3kvdmlyb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+TWlkZGxlIEVhc3QgUmVzcGlyYXRv cnkgU3luZHJvbWUgQ29yb25hdmlydXMvZHJ1ZyBlZmZlY3RzL3BhdGhvZ2VuaWNpdHk8L2tleXdv cmQ+PGtleXdvcmQ+KlBhbmRlbWljcy9wcmV2ZW50aW9uICZhbXA7IGNvbnRyb2w8L2tleXdvcmQ+ PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC9kcnVnIHRoZXJhcHkvKmVwaWRlbWlvbG9neS9wcmV2 ZW50aW9uICZhbXA7IGNvbnRyb2wvdHJhbnNtaXNzaW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZh bGVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+U0FSUyBWaXJ1cy9kcnVnIGVmZmVjdHMvcGF0aG9nZW5p Y2l0eTwva2V5d29yZD48a2V5d29yZD5TZXZlcmUgQWN1dGUgUmVzcGlyYXRvcnkgU3luZHJvbWUv ZHJ1ZyB0aGVyYXB5LyplcGlkZW1pb2xvZ3kvcHJldmVudGlvbiAmYW1wOyBjb250cm9sL3RyYW5z bWlzc2lvbjwva2V5d29yZD48a2V5d29yZD5TdXJ2aXZhbCBBbmFseXNpczwva2V5d29yZD48a2V5 d29yZD5UaHJvbWJvY3l0b3BlbmlhL3BoeXNpb3BhdGhvbG9neS92aXJvbG9neTwva2V5d29yZD48 a2V5d29yZD5WaXJhbCBWYWNjaW5lcy9iaW9zeW50aGVzaXM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48 ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSBhbmQg U29ucyBJbmMuPC9wdWJsaXNoZXI+PGlzYm4+MTA5Ni05MDcxJiN4RDswMTQ2LTY2MTU8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMzQxMTY8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJs cz48dXJsPmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQxMTY8L3VybD48dXJs Pmh0dHBzOi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcyMjgzNDcvPC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDAy L2ptdi4yNTc0ODwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1uYW1l PlB1Yk1lZDwvcmVtb3RlLWRhdGFiYXNlLW5hbWU+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9y ZWNvcmQ+PC9DaXRlPjwvRW5kTm90ZT4A ADDIN EN.CITE.DATA (9). همچنین نتایج مطالعهای دیگر حاکی از این بود که در سیتیاسکن ریه بیشتر بیماران مبتلا به کووید-19، کدورتهایی با الگوی گراندگلاس و یا ترکیبی از گراندگلاس و کانسالیدیشن مشهود میباشد. همچنین احتمال دارد که ضایعات بیشتر به صورت انفیلتراسیون محیطی و با درگیری دوطرفه و غالبا در قسمت تحتانی ریه و به صورت چندکانونی باشند PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaGFvPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY3PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxOCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+Njc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjY3PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaGFvLCBXLjwvYXV0aG9yPjxhdXRob3I+Wmhvbmcs IFouPC9hdXRob3I+PGF1dGhvcj5YaWUsIFguPC9hdXRob3I+PGF1dGhvcj5ZdSwgUS48L2F1dGhv cj48YXV0aG9yPkxpdSwgSi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgt YWRkcmVzcz5EZXBhcnRtZW50IG9mIFJhZGlvbG9neSwgVGhlIFNlY29uZCBYaWFuZ3lhIEhvc3Bp dGFsLCBDZW50cmFsIFNvdXRoIFVuaXZlcnNpdHksIE5vLiAxMzkgTWlkZGxlIFJlbWluIFJkLCBD aGFuZ3NoYSwgSHVuYW4sIDQxMDAxMSwgUC5SLiBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUmFk aW9sb2d5LCBGaXJzdCBIb3NwaXRhbCBvZiBDaGFuZ3NoYSwgSHVuYW4sIFAuUi4gQ2hpbmEuJiN4 RDtDaGFuZ3NoYSBQdWJsaWMgSGVhbHRoIFRyZWF0bWVudCBDZW50ZXIsIEh1bmFuLCBQLlIuIENo aW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSYWRpb2xvZ3ksIFF1YWxpdHkgQ29udHJvbCBDZW50ZXIs IENoYW5nc2hhLCBIdW5hbiwgUC5SLiBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRs ZT5SZWxhdGlvbiBCZXR3ZWVuIENoZXN0IENUIEZpbmRpbmdzIGFuZCBDbGluaWNhbCBDb25kaXRp b25zIG9mIENvcm9uYXZpcnVzIERpc2Vhc2UgKENPVklELTE5KSBQbmV1bW9uaWE6IEEgTXVsdGlj ZW50ZXIgU3R1ZHk8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+QUpSIEFtIEogUm9lbnRnZW5vbDwv c2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+QUpSLiBBbWVyaWNhbiBqb3VybmFsIG9mIHJvZW50 Z2Vub2xvZ3k8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5BSlIg QW0gSiBSb2VudGdlbm9sPC9mdWxsLXRpdGxlPjxhYmJyLTE+QUpSLiBBbWVyaWNhbiBqb3VybmFs IG9mIHJvZW50Z2Vub2xvZ3k8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkFKUiBBbSBKIFJvZW50Z2Vub2w8L2Z1bGwtdGl0bGU+PGFiYnItMT5BSlIuIEFt ZXJpY2FuIGpvdXJuYWwgb2Ygcm9lbnRnZW5vbG9neTwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+ PHBhZ2VzPjEwNzItMTA3NzwvcGFnZXM+PHZvbHVtZT4yMTQ8L3ZvbHVtZT48bnVtYmVyPjU8L251 bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzA0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZG9s ZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tl eXdvcmQ+PGtleXdvcmQ+KkJldGFjb3JvbmF2aXJ1czwva2V5d29yZD48a2V5d29yZD5Db3JvbmF2 aXJ1cyBJbmZlY3Rpb25zLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3 b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3 b3JkPk1pZGRsZSBBZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPlBhbmRlbWljczwva2V5d29yZD48a2V5 d29yZD5QbmV1bW9uaWEsIFZpcmFsLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+U2V2ZXJp dHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48a2V5d29yZD4qVG9tb2dyYXBoeSwgWC1SYXkg Q29tcHV0ZWQ8L2tleXdvcmQ+PGtleXdvcmQ+WW91bmcgQWR1bHQ8L2tleXdvcmQ+PC9rZXl3b3Jk cz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48cHViLWRhdGVzPjxkYXRlPk1heTwvZGF0ZT48L3B1 Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjAzNjEtODAzeDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjEy NTg3MzwvYWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVt PjEwLjIyMTQvYWpyLjIwLjIyOTc2PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRh dGFiYXNlLXByb3ZpZGVyPk5sbTwvcmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxsYW5ndWFnZT5l bmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaGFvPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjY3PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxOCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+Njc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjY3PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaGFvLCBXLjwvYXV0aG9yPjxhdXRob3I+Wmhvbmcs IFouPC9hdXRob3I+PGF1dGhvcj5YaWUsIFguPC9hdXRob3I+PGF1dGhvcj5ZdSwgUS48L2F1dGhv cj48YXV0aG9yPkxpdSwgSi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgt YWRkcmVzcz5EZXBhcnRtZW50IG9mIFJhZGlvbG9neSwgVGhlIFNlY29uZCBYaWFuZ3lhIEhvc3Bp dGFsLCBDZW50cmFsIFNvdXRoIFVuaXZlcnNpdHksIE5vLiAxMzkgTWlkZGxlIFJlbWluIFJkLCBD aGFuZ3NoYSwgSHVuYW4sIDQxMDAxMSwgUC5SLiBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUmFk aW9sb2d5LCBGaXJzdCBIb3NwaXRhbCBvZiBDaGFuZ3NoYSwgSHVuYW4sIFAuUi4gQ2hpbmEuJiN4 RDtDaGFuZ3NoYSBQdWJsaWMgSGVhbHRoIFRyZWF0bWVudCBDZW50ZXIsIEh1bmFuLCBQLlIuIENo aW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSYWRpb2xvZ3ksIFF1YWxpdHkgQ29udHJvbCBDZW50ZXIs IENoYW5nc2hhLCBIdW5hbiwgUC5SLiBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRs ZT5SZWxhdGlvbiBCZXR3ZWVuIENoZXN0IENUIEZpbmRpbmdzIGFuZCBDbGluaWNhbCBDb25kaXRp b25zIG9mIENvcm9uYXZpcnVzIERpc2Vhc2UgKENPVklELTE5KSBQbmV1bW9uaWE6IEEgTXVsdGlj ZW50ZXIgU3R1ZHk8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+QUpSIEFtIEogUm9lbnRnZW5vbDwv c2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+QUpSLiBBbWVyaWNhbiBqb3VybmFsIG9mIHJvZW50 Z2Vub2xvZ3k8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5BSlIg QW0gSiBSb2VudGdlbm9sPC9mdWxsLXRpdGxlPjxhYmJyLTE+QUpSLiBBbWVyaWNhbiBqb3VybmFs IG9mIHJvZW50Z2Vub2xvZ3k8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkFKUiBBbSBKIFJvZW50Z2Vub2w8L2Z1bGwtdGl0bGU+PGFiYnItMT5BSlIuIEFt ZXJpY2FuIGpvdXJuYWwgb2Ygcm9lbnRnZW5vbG9neTwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+ PHBhZ2VzPjEwNzItMTA3NzwvcGFnZXM+PHZvbHVtZT4yMTQ8L3ZvbHVtZT48bnVtYmVyPjU8L251 bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzA0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZG9s ZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tl eXdvcmQ+PGtleXdvcmQ+KkJldGFjb3JvbmF2aXJ1czwva2V5d29yZD48a2V5d29yZD5Db3JvbmF2 aXJ1cyBJbmZlY3Rpb25zLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3 b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3 b3JkPk1pZGRsZSBBZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPlBhbmRlbWljczwva2V5d29yZD48a2V5 d29yZD5QbmV1bW9uaWEsIFZpcmFsLypkaWFnbm9zaXM8L2tleXdvcmQ+PGtleXdvcmQ+U2V2ZXJp dHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48a2V5d29yZD4qVG9tb2dyYXBoeSwgWC1SYXkg Q29tcHV0ZWQ8L2tleXdvcmQ+PGtleXdvcmQ+WW91bmcgQWR1bHQ8L2tleXdvcmQ+PC9rZXl3b3Jk cz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48cHViLWRhdGVzPjxkYXRlPk1heTwvZGF0ZT48L3B1 Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjAzNjEtODAzeDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjEy NTg3MzwvYWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVt PjEwLjIyMTQvYWpyLjIwLjIyOTc2PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRh dGFiYXNlLXByb3ZpZGVyPk5sbTwvcmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxsYW5ndWFnZT5l bmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE.DATA (18). این در حالی است که پلورالافیوژن، لنفادنوپاتی و کلسیفیکاسیون به ندرت گزارش میشود ADDIN EN.CITE <EndNote><Cite><Author>Pan</Author><Year>2020</Year><RecNum>68</RecNum><DisplayText>(19)</DisplayText><record><rec-number>68</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">68</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Pan, Y.</author><author>Guan, H.</author><author>Zhou, S.</author><author>Wang, Y.</author><author>Li, Q.</author><author>Zhu, T.</author><author>Hu, Q.</author><author>Xia, L.</author></authors></contributors><auth-address>Department of radiology, Tongji hospital, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.Department of radiology, Tongji hospital, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China. qjhu@outlook.com.</auth-address><titles><title>Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China</title></titles><pages>3306-3309</pages><volume>30</volume><number>6</number><dates><year>2020</year><pub-dates><date>Jun</date></pub-dates></dates><isbn>0938-7994 (Print)0938-7994</isbn><accession-num>32055945</accession-num><urls></urls><electronic-resource-num>10.1007/s00330-020-06731-x</electronic-resource-num><remote-database-provider>Nlm</remote-database-provider></record></Cite></EndNote>(19). با توجه به شیوع گستردهی این بیماری و مرگ و میر ناشی از آن بخصوص در سالمندان لازم است افراد توجه بیشتری به جلوگیری از شیوع این بیماری داشته‌ باشند PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YdTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051 bT43MDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMik8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJlYy1u dW1iZXI+NzA8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlkPSI5 cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjcwPC9rZXk+PC9mb3JlaWduLWtl eXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250cmli dXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5YdSwgWi48L2F1dGhvcj48YXV0aG9yPlNoaSwgTC48L2F1 dGhvcj48YXV0aG9yPldhbmcsIFkuPC9hdXRob3I+PGF1dGhvcj5aaGFuZywgSi48L2F1dGhvcj48 YXV0aG9yPkh1YW5nLCBMLjwvYXV0aG9yPjxhdXRob3I+WmhhbmcsIEMuPC9hdXRob3I+PGF1dGhv cj5MaXUsIFMuPC9hdXRob3I+PGF1dGhvcj5aaGFvLCBQLjwvYXV0aG9yPjxhdXRob3I+TGl1LCBI LjwvYXV0aG9yPjxhdXRob3I+Wmh1LCBMLjwvYXV0aG9yPjxhdXRob3I+VGFpLCBZLjwvYXV0aG9y PjxhdXRob3I+QmFpLCBDLjwvYXV0aG9yPjxhdXRob3I+R2FvLCBULjwvYXV0aG9yPjxhdXRob3I+ U29uZywgSi48L2F1dGhvcj48YXV0aG9yPlhpYSwgUC48L2F1dGhvcj48YXV0aG9yPkRvbmcsIEou PC9hdXRob3I+PGF1dGhvcj5aaGFvLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgRi4gUy48L2F1 dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5UcmVhdG1lbnQgYW5k IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGlj YWwgQ2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNl YXJjaCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGlu YS4mI3hEO0RlcGFydG1lbnQgb2YgUGF0aG9sb2d5IGFuZCBIZXBhdG9sb2d5LCBUaGUgRmlmdGgg TWVkaWNhbCBDZW50ZXIgb2YgUExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2Fs IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzks IENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSZXNwaXJhdGlvbiwgVGhlIEZpZnRoIE1lZGljYWwg Q2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJj aCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4m I3hEO0RlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBUaGUgRmlmdGggTWVkaWNhbCBDZW50ZXIgb2Yg UExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRlciBm b3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzksIENoaW5hLiYjeEQ7RGVwYXJ0 bWVudCBvZiBQYXRob2xvZ3kgYW5kIEhlcGF0b2xvZ3ksIFRoZSBGaWZ0aCBNZWRpY2FsIENlbnRl ciBvZiBQTEEgR2VuZXJhbCBIb3NwaXRhbCwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2Vu dGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vhc2VzLCBCZWlqaW5nIDEwMDAzOSwgQ2hpbmEuIEVsZWN0 cm9uaWMgYWRkcmVzczogam16aGFvMzAyQDE2My5jb20uJiN4RDtUcmVhdG1lbnQgYW5kIFJlc2Vh cmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGljYWwgQ2Vu dGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4gRWxl Y3Ryb25pYyBhZGRyZXNzOiBmc3dhbmczMDJAMTYzLmNvbS48L2F1dGgtYWRkcmVzcz48dGl0bGVz Pjx0aXRsZT5QYXRob2xvZ2ljYWwgZmluZGluZ3Mgb2YgQ09WSUQtMTkgYXNzb2NpYXRlZCB3aXRo IGFjdXRlIHJlc3BpcmF0b3J5IGRpc3RyZXNzIHN5bmRyb21lPC90aXRsZT48c2Vjb25kYXJ5LXRp dGxlPkxhbmNldCBSZXNwaXIgTWVkPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5UaGUgTGFu Y2V0LiBSZXNwaXJhdG9yeSBtZWRpY2luZTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2Fs PjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+VGhlIExh bmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJp b2RpY2FsPjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+ VGhlIExhbmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2Fs PjxwYWdlcz40MjAtNDIyPC9wYWdlcz48dm9sdW1lPjg8L3ZvbHVtZT48bnVtYmVyPjQ8L251bWJl cj48ZWRpdGlvbj4yMDIwLzAyLzIzPC9lZGl0aW9uPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxw dWItZGF0ZXM+PGRhdGU+QXByPC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MjIxMy0y NjAwIChQcmludCkmI3hEOzIyMTMtMjYwMDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjA4NTg0Njwv YWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGN1c3RvbTI+UG1jNzE2NDc3MTwvY3VzdG9tMj48 ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9zMjIxMy0yNjAwKDIwKTMwMDc2LXg8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1v dGUtZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9D aXRlPjwvRW5kTm90ZT5= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YdTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051 bT43MDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMik8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJlYy1u dW1iZXI+NzA8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlkPSI5 cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjcwPC9rZXk+PC9mb3JlaWduLWtl eXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250cmli dXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5YdSwgWi48L2F1dGhvcj48YXV0aG9yPlNoaSwgTC48L2F1 dGhvcj48YXV0aG9yPldhbmcsIFkuPC9hdXRob3I+PGF1dGhvcj5aaGFuZywgSi48L2F1dGhvcj48 YXV0aG9yPkh1YW5nLCBMLjwvYXV0aG9yPjxhdXRob3I+WmhhbmcsIEMuPC9hdXRob3I+PGF1dGhv cj5MaXUsIFMuPC9hdXRob3I+PGF1dGhvcj5aaGFvLCBQLjwvYXV0aG9yPjxhdXRob3I+TGl1LCBI LjwvYXV0aG9yPjxhdXRob3I+Wmh1LCBMLjwvYXV0aG9yPjxhdXRob3I+VGFpLCBZLjwvYXV0aG9y PjxhdXRob3I+QmFpLCBDLjwvYXV0aG9yPjxhdXRob3I+R2FvLCBULjwvYXV0aG9yPjxhdXRob3I+ U29uZywgSi48L2F1dGhvcj48YXV0aG9yPlhpYSwgUC48L2F1dGhvcj48YXV0aG9yPkRvbmcsIEou PC9hdXRob3I+PGF1dGhvcj5aaGFvLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgRi4gUy48L2F1 dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5UcmVhdG1lbnQgYW5k IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGlj YWwgQ2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNl YXJjaCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGlu YS4mI3hEO0RlcGFydG1lbnQgb2YgUGF0aG9sb2d5IGFuZCBIZXBhdG9sb2d5LCBUaGUgRmlmdGgg TWVkaWNhbCBDZW50ZXIgb2YgUExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2Fs IFJlc2VhcmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzks IENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBSZXNwaXJhdGlvbiwgVGhlIEZpZnRoIE1lZGljYWwg Q2VudGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJj aCBDZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4m I3hEO0RlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBUaGUgRmlmdGggTWVkaWNhbCBDZW50ZXIgb2Yg UExBIEdlbmVyYWwgSG9zcGl0YWwsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRlciBm b3IgSW5mZWN0aW91cyBEaXNlYXNlcywgQmVpamluZyAxMDAwMzksIENoaW5hLiYjeEQ7RGVwYXJ0 bWVudCBvZiBQYXRob2xvZ3kgYW5kIEhlcGF0b2xvZ3ksIFRoZSBGaWZ0aCBNZWRpY2FsIENlbnRl ciBvZiBQTEEgR2VuZXJhbCBIb3NwaXRhbCwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2Vu dGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vhc2VzLCBCZWlqaW5nIDEwMDAzOSwgQ2hpbmEuIEVsZWN0 cm9uaWMgYWRkcmVzczogam16aGFvMzAyQDE2My5jb20uJiN4RDtUcmVhdG1lbnQgYW5kIFJlc2Vh cmNoIENlbnRlciBmb3IgSW5mZWN0aW91cyBEaXNlYXNlcywgVGhlIEZpZnRoIE1lZGljYWwgQ2Vu dGVyIG9mIFBMQSBHZW5lcmFsIEhvc3BpdGFsLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIEluZmVjdGlvdXMgRGlzZWFzZXMsIEJlaWppbmcgMTAwMDM5LCBDaGluYS4gRWxl Y3Ryb25pYyBhZGRyZXNzOiBmc3dhbmczMDJAMTYzLmNvbS48L2F1dGgtYWRkcmVzcz48dGl0bGVz Pjx0aXRsZT5QYXRob2xvZ2ljYWwgZmluZGluZ3Mgb2YgQ09WSUQtMTkgYXNzb2NpYXRlZCB3aXRo IGFjdXRlIHJlc3BpcmF0b3J5IGRpc3RyZXNzIHN5bmRyb21lPC90aXRsZT48c2Vjb25kYXJ5LXRp dGxlPkxhbmNldCBSZXNwaXIgTWVkPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5UaGUgTGFu Y2V0LiBSZXNwaXJhdG9yeSBtZWRpY2luZTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2Fs PjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+VGhlIExh bmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJp b2RpY2FsPjxmdWxsLXRpdGxlPkxhbmNldCBSZXNwaXIgTWVkPC9mdWxsLXRpdGxlPjxhYmJyLTE+ VGhlIExhbmNldC4gUmVzcGlyYXRvcnkgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2Fs PjxwYWdlcz40MjAtNDIyPC9wYWdlcz48dm9sdW1lPjg8L3ZvbHVtZT48bnVtYmVyPjQ8L251bWJl cj48ZWRpdGlvbj4yMDIwLzAyLzIzPC9lZGl0aW9uPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxw dWItZGF0ZXM+PGRhdGU+QXByPC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MjIxMy0y NjAwIChQcmludCkmI3hEOzIyMTMtMjYwMDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjA4NTg0Njwv YWNjZXNzaW9uLW51bT48dXJscz48L3VybHM+PGN1c3RvbTI+UG1jNzE2NDc3MTwvY3VzdG9tMj48 ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9zMjIxMy0yNjAwKDIwKTMwMDc2LXg8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1v dGUtZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9D aXRlPjwvRW5kTm90ZT5= ADDIN EN.CITE.DATA (2). همچنین لازم است در جمعیتهای پرخطر از جمله کودکان، کارکنان بهداشتی و در سالمندان (به دلیل سیستم ایمنی ضعیفتر) اقداماتی انجام شود ADDIN EN.CITE <EndNote><Cite><Author>Rothan</Author><Year>2020</Year><RecNum>73</RecNum><DisplayText>(20)</DisplayText><record><rec-number>73</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">73</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Rothan, Hussin A.</author><author>Byrareddy, Siddappa N.</author></authors></contributors><titles><title>The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak</title><secondary-title>Journal of Autoimmunity</secondary-title></titles><periodical><full-title>Journal of autoimmunity</full-title><abbr-1>J Autoimmun</abbr-1></periodical><pages>102433</pages><volume>109</volume><keywords><keyword>Coronavirus</keyword><keyword>COVID-19</keyword><keyword>Wuhan city</keyword><keyword>Pneumonia</keyword><keyword>Pathogenesis</keyword></keywords><dates><year>2020</year><pub-dates><date>2020/05/01/</date></pub-dates></dates><isbn>0896-8411</isbn><urls><related-urls><url>http://www.sciencedirect.com/science/article/pii/S0896841120300469</url></related-urls></urls><electronic-resource-num>https://doi.org/10.1016/j.jaut.2020.102433</electronic-resource-num></record></Cite></EndNote>(20). با توجه به این موضوع، در دسترس بودن دادههای بالینی، آزمایشگاهی و رادیولوژیکی دقیق و قوی در بروز این بیماری همهگیر، جهت هدایت تصمیم‌گیری در مورد بهداشت عمومی لازم و ضروری میباشد PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5Nb3JnYW48L0F1dGhvcj48WWVhcj4yMDE5PC9ZZWFyPjxS ZWNOdW0+NzI8L1JlY051bT48RGlzcGxheVRleHQ+KDIxKTwvRGlzcGxheVRleHQ+PHJlY29yZD48 cmVjLW51bWJlcj43MjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGIt aWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NzI8L2tleT48L2ZvcmVp Z24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNv bnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk1vcmdhbiwgTy48L2F1dGhvcj48L2F1dGhvcnM+ PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5EZXBhcnRtZW50IG9mIEhlYWx0aCBFbWVyZ2Vu Y3kgSW5mb3JtYXRpb24gYW5kIFJpc2sgQXNzZXNzbWVudCwgSGVhbHRoIEVtZXJnZW5jaWVzIFBy b2dyYW1tZSwgV29ybGQgSGVhbHRoIE9yZ2FuaXphdGlvbiAsIEdlbmV2YSAsIFN3aXR6ZXJsYW5k LjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkhvdyBkZWNpc2lvbiBtYWtlcnMgY2FuIHVz ZSBxdWFudGl0YXRpdmUgYXBwcm9hY2hlcyB0byBndWlkZSBvdXRicmVhayByZXNwb25zZXM8L3Rp dGxlPjxzZWNvbmRhcnktdGl0bGU+UGhpbG9zIFRyYW5zIFIgU29jIExvbmQgQiBCaW9sIFNjaTwv c2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+UGhpbG9zb3BoaWNhbCB0cmFuc2FjdGlvbnMgb2Yg dGhlIFJveWFsIFNvY2lldHkgb2YgTG9uZG9uLiBTZXJpZXMgQiwgQmlvbG9naWNhbCBzY2llbmNl czwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBoaWxvcyBUcmFu cyBSIFNvYyBMb25kIEIgQmlvbCBTY2k8L2Z1bGwtdGl0bGU+PGFiYnItMT5QaGlsb3NvcGhpY2Fs IHRyYW5zYWN0aW9ucyBvZiB0aGUgUm95YWwgU29jaWV0eSBvZiBMb25kb24uIFNlcmllcyBCLCBC aW9sb2dpY2FsIHNjaWVuY2VzPC9hYmJyLTE+PC9wZXJpb2RpY2FsPjxhbHQtcGVyaW9kaWNhbD48 ZnVsbC10aXRsZT5QaGlsb3MgVHJhbnMgUiBTb2MgTG9uZCBCIEJpb2wgU2NpPC9mdWxsLXRpdGxl PjxhYmJyLTE+UGhpbG9zb3BoaWNhbCB0cmFuc2FjdGlvbnMgb2YgdGhlIFJveWFsIFNvY2lldHkg b2YgTG9uZG9uLiBTZXJpZXMgQiwgQmlvbG9naWNhbCBzY2llbmNlczwvYWJici0xPjwvYWx0LXBl cmlvZGljYWw+PHBhZ2VzPjIwMTgwMzY1PC9wYWdlcz48dm9sdW1lPjM3NDwvdm9sdW1lPjxudW1i ZXI+MTc3NjwvbnVtYmVyPjxlZGl0aW9uPjIwMTkvMDUvMjE8L2VkaXRpb24+PGtleXdvcmRzPjxr ZXl3b3JkPkRhdGEgU2NpZW5jZTwva2V5d29yZD48a2V5d29yZD4qRGVjaXNpb24gTWFraW5nPC9r ZXl3b3JkPjxrZXl3b3JkPkRpc2Vhc2UgT3V0YnJlYWtzLypwcmV2ZW50aW9uICZhbXA7IGNvbnRy b2w8L2tleXdvcmQ+PGtleXdvcmQ+SHVtYW5zPC9rZXl3b3JkPjxrZXl3b3JkPipNb2RlbHMsIEJp b2xvZ2ljYWw8L2tleXdvcmQ+PGtleXdvcmQ+UHVibGljIEhlYWx0aC8qbWV0aG9kczwva2V5d29y ZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4yMDE5PC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+SnVs IDg8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRlcz48aXNibj4wOTYyLTg0MzYgKFByaW50KSYjeEQ7 MDk2Mi04NDM2PC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMxMTA0NjA1PC9hY2Nlc3Npb24tbnVtPjx1 cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM2NTU4NTU4PC9jdXN0b20yPjxlbGVjdHJvbmljLXJlc291 cmNlLW51bT4xMC4xMDk4L3JzdGIuMjAxOC4wMzY1PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48 cmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPk5sbTwvcmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxs YW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48Q2l0ZT48QXV0aG9yPk1vcmdh bjwvQXV0aG9yPjxZZWFyPjIwMTk8L1llYXI+PFJlY051bT43MjwvUmVjTnVtPjxyZWNvcmQ+PHJl Yy1udW1iZXI+NzI8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjcyPC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5Nb3JnYW4sIE8uPC9hdXRob3I+PC9hdXRob3JzPjwv Y29udHJpYnV0b3JzPjxhdXRoLWFkZHJlc3M+RGVwYXJ0bWVudCBvZiBIZWFsdGggRW1lcmdlbmN5 IEluZm9ybWF0aW9uIGFuZCBSaXNrIEFzc2Vzc21lbnQsIEhlYWx0aCBFbWVyZ2VuY2llcyBQcm9n cmFtbWUsIFdvcmxkIEhlYWx0aCBPcmdhbml6YXRpb24gLCBHZW5ldmEgLCBTd2l0emVybGFuZC48 L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRsZT5Ib3cgZGVjaXNpb24gbWFrZXJzIGNhbiB1c2Ug cXVhbnRpdGF0aXZlIGFwcHJvYWNoZXMgdG8gZ3VpZGUgb3V0YnJlYWsgcmVzcG9uc2VzPC90aXRs ZT48c2Vjb25kYXJ5LXRpdGxlPlBoaWxvcyBUcmFucyBSIFNvYyBMb25kIEIgQmlvbCBTY2k8L3Nl Y29uZGFyeS10aXRsZT48YWx0LXRpdGxlPlBoaWxvc29waGljYWwgdHJhbnNhY3Rpb25zIG9mIHRo ZSBSb3lhbCBTb2NpZXR5IG9mIExvbmRvbi4gU2VyaWVzIEIsIEJpb2xvZ2ljYWwgc2NpZW5jZXM8 L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5QaGlsb3MgVHJhbnMg UiBTb2MgTG9uZCBCIEJpb2wgU2NpPC9mdWxsLXRpdGxlPjxhYmJyLTE+UGhpbG9zb3BoaWNhbCB0 cmFuc2FjdGlvbnMgb2YgdGhlIFJveWFsIFNvY2lldHkgb2YgTG9uZG9uLiBTZXJpZXMgQiwgQmlv bG9naWNhbCBzY2llbmNlczwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1 bGwtdGl0bGU+UGhpbG9zIFRyYW5zIFIgU29jIExvbmQgQiBCaW9sIFNjaTwvZnVsbC10aXRsZT48 YWJici0xPlBoaWxvc29waGljYWwgdHJhbnNhY3Rpb25zIG9mIHRoZSBSb3lhbCBTb2NpZXR5IG9m IExvbmRvbi4gU2VyaWVzIEIsIEJpb2xvZ2ljYWwgc2NpZW5jZXM8L2FiYnItMT48L2FsdC1wZXJp b2RpY2FsPjxwYWdlcz4yMDE4MDM2NTwvcGFnZXM+PHZvbHVtZT4zNzQ8L3ZvbHVtZT48bnVtYmVy PjE3NzY8L251bWJlcj48ZWRpdGlvbj4yMDE5LzA1LzIxPC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5 d29yZD5EYXRhIFNjaWVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+KkRlY2lzaW9uIE1ha2luZzwva2V5 d29yZD48a2V5d29yZD5EaXNlYXNlIE91dGJyZWFrcy8qcHJldmVudGlvbiAmYW1wOyBjb250cm9s PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD4qTW9kZWxzLCBCaW9s b2dpY2FsPC9rZXl3b3JkPjxrZXl3b3JkPlB1YmxpYyBIZWFsdGgvKm1ldGhvZHM8L2tleXdvcmQ+ PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAxOTwveWVhcj48cHViLWRhdGVzPjxkYXRlPkp1bCA4 PC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MDk2Mi04NDM2IChQcmludCkmI3hEOzA5 NjItODQzNjwvaXNibj48YWNjZXNzaW9uLW51bT4zMTEwNDYwNTwvYWNjZXNzaW9uLW51bT48dXJs cz48L3VybHM+PGN1c3RvbTI+UG1jNjU1ODU1ODwvY3VzdG9tMj48ZWxlY3Ryb25pYy1yZXNvdXJj ZS1udW0+MTAuMTA5OC9yc3RiLjIwMTguMDM2NTwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJl bW90ZS1kYXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFu Z3VhZ2U+ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5Nb3JnYW48L0F1dGhvcj48WWVhcj4yMDE5PC9ZZWFyPjxS ZWNOdW0+NzI8L1JlY051bT48RGlzcGxheVRleHQ+KDIxKTwvRGlzcGxheVRleHQ+PHJlY29yZD48 cmVjLW51bWJlcj43MjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGIt aWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NzI8L2tleT48L2ZvcmVp Z24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNv bnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk1vcmdhbiwgTy48L2F1dGhvcj48L2F1dGhvcnM+ PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5EZXBhcnRtZW50IG9mIEhlYWx0aCBFbWVyZ2Vu Y3kgSW5mb3JtYXRpb24gYW5kIFJpc2sgQXNzZXNzbWVudCwgSGVhbHRoIEVtZXJnZW5jaWVzIFBy b2dyYW1tZSwgV29ybGQgSGVhbHRoIE9yZ2FuaXphdGlvbiAsIEdlbmV2YSAsIFN3aXR6ZXJsYW5k LjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkhvdyBkZWNpc2lvbiBtYWtlcnMgY2FuIHVz ZSBxdWFudGl0YXRpdmUgYXBwcm9hY2hlcyB0byBndWlkZSBvdXRicmVhayByZXNwb25zZXM8L3Rp dGxlPjxzZWNvbmRhcnktdGl0bGU+UGhpbG9zIFRyYW5zIFIgU29jIExvbmQgQiBCaW9sIFNjaTwv c2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+UGhpbG9zb3BoaWNhbCB0cmFuc2FjdGlvbnMgb2Yg dGhlIFJveWFsIFNvY2lldHkgb2YgTG9uZG9uLiBTZXJpZXMgQiwgQmlvbG9naWNhbCBzY2llbmNl czwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBoaWxvcyBUcmFu cyBSIFNvYyBMb25kIEIgQmlvbCBTY2k8L2Z1bGwtdGl0bGU+PGFiYnItMT5QaGlsb3NvcGhpY2Fs IHRyYW5zYWN0aW9ucyBvZiB0aGUgUm95YWwgU29jaWV0eSBvZiBMb25kb24uIFNlcmllcyBCLCBC aW9sb2dpY2FsIHNjaWVuY2VzPC9hYmJyLTE+PC9wZXJpb2RpY2FsPjxhbHQtcGVyaW9kaWNhbD48 ZnVsbC10aXRsZT5QaGlsb3MgVHJhbnMgUiBTb2MgTG9uZCBCIEJpb2wgU2NpPC9mdWxsLXRpdGxl PjxhYmJyLTE+UGhpbG9zb3BoaWNhbCB0cmFuc2FjdGlvbnMgb2YgdGhlIFJveWFsIFNvY2lldHkg b2YgTG9uZG9uLiBTZXJpZXMgQiwgQmlvbG9naWNhbCBzY2llbmNlczwvYWJici0xPjwvYWx0LXBl cmlvZGljYWw+PHBhZ2VzPjIwMTgwMzY1PC9wYWdlcz48dm9sdW1lPjM3NDwvdm9sdW1lPjxudW1i ZXI+MTc3NjwvbnVtYmVyPjxlZGl0aW9uPjIwMTkvMDUvMjE8L2VkaXRpb24+PGtleXdvcmRzPjxr ZXl3b3JkPkRhdGEgU2NpZW5jZTwva2V5d29yZD48a2V5d29yZD4qRGVjaXNpb24gTWFraW5nPC9r ZXl3b3JkPjxrZXl3b3JkPkRpc2Vhc2UgT3V0YnJlYWtzLypwcmV2ZW50aW9uICZhbXA7IGNvbnRy b2w8L2tleXdvcmQ+PGtleXdvcmQ+SHVtYW5zPC9rZXl3b3JkPjxrZXl3b3JkPipNb2RlbHMsIEJp b2xvZ2ljYWw8L2tleXdvcmQ+PGtleXdvcmQ+UHVibGljIEhlYWx0aC8qbWV0aG9kczwva2V5d29y ZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4yMDE5PC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+SnVs IDg8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRlcz48aXNibj4wOTYyLTg0MzYgKFByaW50KSYjeEQ7 MDk2Mi04NDM2PC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMxMTA0NjA1PC9hY2Nlc3Npb24tbnVtPjx1 cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM2NTU4NTU4PC9jdXN0b20yPjxlbGVjdHJvbmljLXJlc291 cmNlLW51bT4xMC4xMDk4L3JzdGIuMjAxOC4wMzY1PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48 cmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPk5sbTwvcmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxs YW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48Q2l0ZT48QXV0aG9yPk1vcmdh bjwvQXV0aG9yPjxZZWFyPjIwMTk8L1llYXI+PFJlY051bT43MjwvUmVjTnVtPjxyZWNvcmQ+PHJl Yy1udW1iZXI+NzI8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjcyPC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5Nb3JnYW4sIE8uPC9hdXRob3I+PC9hdXRob3JzPjwv Y29udHJpYnV0b3JzPjxhdXRoLWFkZHJlc3M+RGVwYXJ0bWVudCBvZiBIZWFsdGggRW1lcmdlbmN5 IEluZm9ybWF0aW9uIGFuZCBSaXNrIEFzc2Vzc21lbnQsIEhlYWx0aCBFbWVyZ2VuY2llcyBQcm9n cmFtbWUsIFdvcmxkIEhlYWx0aCBPcmdhbml6YXRpb24gLCBHZW5ldmEgLCBTd2l0emVybGFuZC48 L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRsZT5Ib3cgZGVjaXNpb24gbWFrZXJzIGNhbiB1c2Ug cXVhbnRpdGF0aXZlIGFwcHJvYWNoZXMgdG8gZ3VpZGUgb3V0YnJlYWsgcmVzcG9uc2VzPC90aXRs ZT48c2Vjb25kYXJ5LXRpdGxlPlBoaWxvcyBUcmFucyBSIFNvYyBMb25kIEIgQmlvbCBTY2k8L3Nl Y29uZGFyeS10aXRsZT48YWx0LXRpdGxlPlBoaWxvc29waGljYWwgdHJhbnNhY3Rpb25zIG9mIHRo ZSBSb3lhbCBTb2NpZXR5IG9mIExvbmRvbi4gU2VyaWVzIEIsIEJpb2xvZ2ljYWwgc2NpZW5jZXM8 L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5QaGlsb3MgVHJhbnMg UiBTb2MgTG9uZCBCIEJpb2wgU2NpPC9mdWxsLXRpdGxlPjxhYmJyLTE+UGhpbG9zb3BoaWNhbCB0 cmFuc2FjdGlvbnMgb2YgdGhlIFJveWFsIFNvY2lldHkgb2YgTG9uZG9uLiBTZXJpZXMgQiwgQmlv bG9naWNhbCBzY2llbmNlczwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1 bGwtdGl0bGU+UGhpbG9zIFRyYW5zIFIgU29jIExvbmQgQiBCaW9sIFNjaTwvZnVsbC10aXRsZT48 YWJici0xPlBoaWxvc29waGljYWwgdHJhbnNhY3Rpb25zIG9mIHRoZSBSb3lhbCBTb2NpZXR5IG9m IExvbmRvbi4gU2VyaWVzIEIsIEJpb2xvZ2ljYWwgc2NpZW5jZXM8L2FiYnItMT48L2FsdC1wZXJp b2RpY2FsPjxwYWdlcz4yMDE4MDM2NTwvcGFnZXM+PHZvbHVtZT4zNzQ8L3ZvbHVtZT48bnVtYmVy PjE3NzY8L251bWJlcj48ZWRpdGlvbj4yMDE5LzA1LzIxPC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5 d29yZD5EYXRhIFNjaWVuY2U8L2tleXdvcmQ+PGtleXdvcmQ+KkRlY2lzaW9uIE1ha2luZzwva2V5 d29yZD48a2V5d29yZD5EaXNlYXNlIE91dGJyZWFrcy8qcHJldmVudGlvbiAmYW1wOyBjb250cm9s PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD4qTW9kZWxzLCBCaW9s b2dpY2FsPC9rZXl3b3JkPjxrZXl3b3JkPlB1YmxpYyBIZWFsdGgvKm1ldGhvZHM8L2tleXdvcmQ+ PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAxOTwveWVhcj48cHViLWRhdGVzPjxkYXRlPkp1bCA4 PC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MDk2Mi04NDM2IChQcmludCkmI3hEOzA5 NjItODQzNjwvaXNibj48YWNjZXNzaW9uLW51bT4zMTEwNDYwNTwvYWNjZXNzaW9uLW51bT48dXJs cz48L3VybHM+PGN1c3RvbTI+UG1jNjU1ODU1ODwvY3VzdG9tMj48ZWxlY3Ryb25pYy1yZXNvdXJj ZS1udW0+MTAuMTA5OC9yc3RiLjIwMTguMDM2NTwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJl bW90ZS1kYXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFu Z3VhZ2U+ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE.DATA (21). همچنین برای ایجاد آگاهی بالینی بهتر و تخصیص منابع پزشکی، درک تفاوت بین ویژگیهای بیمار در مناطق مختلف مورد نیاز است ADDIN EN.CITE <EndNote><Cite><Author>Aggarwal</Author><Year>2020</Year><RecNum>137</RecNum><DisplayText>(5)</DisplayText><record><rec-number>137</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">137</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Aggarwal, Saurabh</author><author>Garcia-Telles, Nelson</author><author>Aggarwal, Gaurav</author><author>Lavie, Carl</author><author>Lippi, Giuseppe</author><author>Henry, Brandon Michael</author></authors></contributors><titles><title>Clinical features, laboratory characteristics, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19): Early report from the United States</title><secondary-title>Diagnosis</secondary-title></titles><periodical><full-title>Diagnosis</full-title></periodical><pages>91-96</pages><volume>7</volume><number>2</number><dates><year>2020</year></dates><isbn>2194-8011</isbn><urls></urls></record></Cite></EndNote>(5). از این رو جهت دستیابی هر چه بهتر و بیشتر به این هدف، تیم تحقیق مصمم شد مطالعه‌ای توصیفی-مقطعی و با هدف تعیین ویژگیهای بالینی و پاراکلینکی در بیماران بستری مبتلا به کووید-19 در مرکز آموزشی درمانی بوعلی سینای شهر قزوین، که از ابتدای اسفند ماه 1398 تا ابتدای خرداد ماه 1399 در این مرکز بستری بودهاند، انجام دهد.

روش

پژوهشمطالعهی حاضر، یک مطالعهی توصیفی-مقطعی و مبتنی بر پرونده‌های بیمارستانی است. جامعه مورد مطالعه شامل پرونده کلیه بیمارانی بود که در مقطع زمانی سه ماهه از ابتدای اسفند ماه 1399 تا ابتدای خردادماه 1400 در مرکز تخصصی بیماریهای عفونی دانشگاه علوم پزشکی قزوین بستری شده ‌بودند. معیار ورود شامل پرونده بیمارانی بود که تست کووید آن‌ها براساس نتیجهی تست واکنش زنجیرههای پلیمراز معکوس، مثبت و نیز از نظر وجود علائم بالینی و وجود درگیری ریوی به طور قطع مبتلا به پنومونی ناشی از کووید-19 بودهاند و اطلاعات مورد نیاز جهت انجام پژوهش در پروندهی آنها موجود بود. تمامی پرونده‌هایی که برحسب جستجوهای پژوهشگران، اطلاعات لازم و مورد نیاز جهت دستیابی به اهداف مورد نظر طرح را نداشتند، از مطالعه خارج شدند. براساس مطالعه لیلیو و همکاران (2020) در زمینه شیوع علائم بالینی در بیماران مبتلا به کووید-19، 05/0 =α و 05/0 =d، 84/0 =p، 961150826/1 =

1-a/2

در نظر گرفته شد

حجم نمونهها 324 نفر محاسبه گردید ADDIN EN.CITE <EndNote><Cite><Author>Jian-ya</Author><Year>2020</Year><RecNum>117</RecNum><DisplayText>(22)</DisplayText><record><rec-number>117</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">117</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jian-ya, Gao</author></authors></contributors><titles><title>Clinical characteristics of 51 patients discharged from hospital with COVID-19 in Chongqing, China</title><secondary-title>medRxiv</secondary-title></titles><periodical><full-title>medRxiv</full-title></periodical><dates><year>2020</year></dates><urls></urls></record></Cite></EndNote>(22).iVBORw0KGgoAAAANSUhEUgAAAFIAAAA+CAYAAAC4Gky6AAAAAXNSR0ICQMB9xQAAAAlwSFlzAAAO xAAADsQBlSsOGwAAABl0RVh0U29mdHdhcmUATWljcm9zb2Z0IE9mZmljZX/tNXEAAAO+SURBVHja 7Zs9buJAFMfnADlAImXoOAAMlGmdCUqNYkauNkoVjRSlXhk6pGwuQJduU2ydYnMCbpAiN8gddnnj HRgbfwHrsT284kkgLIR/fh//995AZrMZQTvcEAKCRJAIsg4Lw+CMEfJJCPlDvftHBLmnSc8bB2F4 BkD7pP8bXiPIA23C6DOXYQ9BHmiC82938/kJgjzApoJdMzG9xhx5IETCJi9YtQ+we48+QsXW1lSv RA2IIBFk/SJf8h4l5AtSxVDIG5BVKnXQ/tLUqaH0u5zSV90MTBh5yUotR+tBkcCnS+Z5330ZdtV7 Spa6e9KwKRchSK7ofRx0Y0CanrFlFVdppQTO+bvWpfP53Qk/J+8AUr82f0ORcmhURV6bcYPVdUnx MI0eKv2AzklBI+xTe58Gm6cYaoOofhxjTxBWMS/1/d4+/TR83yXrLFQ+u7r6MaCDn1nfk9a3A1jt cebrzQOnX3ntacOKgN9Ngt21D1cPaFUg8m5aeR8dvAFIuF4VG6PQKJAD/guiQorhDePsiVL+mhcl jYEINyTl9HTLayFXGWGW5WGsc7mQU3kq+PChwy4Xfuj3PE+Oy6QUyibPJqRN7qZfUNXh+qIRXmMh xkK2wxZ5IDfANzeelDKxaws8dp/rGwExCORFbu4rALmzUigI021lkS17GgNSCHGVDFMzJP8nSJX7 SioDczJfRo7VClEGwUXyZiAsTZmhQfqh7Ebha1cmNb5FjLRaioZMFJYyHpn+PZE5DTK3o0l42Toc G+R92GsjyPKDiLpWt06BrHN162yo2V7dOgvS9urWSYh1rG4zZQn8EHM0BT1sWyDWsbpNrXyQqGF6 whhX88Ks6Ues5aphyl001bHplZlPVOeYXaclqCMNL4N5npYOu05LEKQhaM2QyBtq7hPaude3yIqL jeF9emXJpRj5PoZ2aY9Mep/erA25eMD2EYcWVtrHowzDKtrHowRZRfvoLCy1mRR8BJ2Z3mFX2T46 CXFrAv9PhlXZPjodwrplBA+sun10vKhAw5B/ZgdBltWNlpZmzoLU615buxs3xPaqOsNp2yj/RaFs M6xbD3IzeF4BE3IUVWy/O6D0TVVti7vwVkPUR/6SZyp1hba5km05xHQZYzusWwtyrQlTxPUasuUj Lu2VNRkeZ7tatxbk+hRbijcWQUaQJQsJjMcoJR91nFxzBqQa3AbeWP1ba/XZVMpTBDkrMdmh/SXI HigugrFQ799VJQ+C26x/NCDImPexWz0mM//aUVehcbrXRpAI8rjtL+KycimizJbFAAAAAElFTkSu QmCC پژوهشگران پس از اخذ کد اخلاق و مجوزهای لازم از دانشگاه علوم پزشکی قزوین وارد محیط پژوهش شده و نمونهها را در مقطع زمانی عنوان شده مورد بررسی قرار دادند. پژوهشگران براساس روش نمونه‌گیری در دسترس، تا زمان رسیدن به حجم نمونه مورد نظر از افراد زنده مانده و فوت شده اقدام به نمونهگیری نمودند. از بین نمونه‌ها، 324 نفر (175 زن و 149 مرد) وارد مطالعه شدند. از پرونده‌های بررسی شده 8 مورد با تست مثبت کووید به بیمارستان دیگر منتقل شدند که از مطالعه خارج شدند. تعداد 38 پرونده هم اطلاعات و شرح‌حال ناقص داشتند که از مطالعه خارج گردیدند. دادهها پس از جمعآوری با استفاده از نرم‌افزار SPSS نسخه 23، تجزیه و تحلیل گردید. جهت توصیف دادههای کمی از میانگین و انحراف معیار و جهت توصیف کیفی از تعداد و درصد استفاده شد. همچنین ارتباط متغیرهای کیفی با آزمون کایاسکوئر، متغیرهای کمی با آزمون همبستگی و متغیرهای کیفی و کمی با آزمونهای تی مستقل یا تحلیل واریانس مورد تحلیل قرار گرفت. در تمامی مراحل سطح معناداری کمتر از 5 درصد لحاظ شد.

یافته

هامطالعهی حاضر با هدف تعیین ویژگیهای بالینی و پاراکلینیکی در بیماران بستری مبتلا به کووید-19 در مرکز آموزشی درمانی منتخب بوعلی سینای قزوین انجام شده ‌است. دادههای بالینی حاصل بررسی 324 بیمار میباشد که از ابتدای مارس 2021 تا ابتدای ژوئن 2021 در مرکز تخصصی بیماریهای عفونی قزوین-ایران بستری بودهاند. تمامی بیمارن براساس نتیجهی تست واکنش زنجیرههای پلیمراز معکوس، مثبت و نیز از نظر وجود علائم بالینی و وجود درگیری ریوی به طور قطع مبتلا به پنومونی ناشی از کووید-19 بودهاند. میانگین سنی بیماران 3/63 سال بوده و تعداد 149 زن (46 درصد) و 175مرد (54 درصد) بودند. از 324 نفر 196 نفر (5/60 درصد) زنده و 128 نفر (5/39 درصد) فوت شدهاند. در مطالعهی حاضر به لحاظ جنسیت هیچگونه تفاوت معناداری بین دو گروه وجود نداشت. اما بیماران متوفی نسبت به گروه بازمانده، مسنتر بودند. به طوری‌که میانگین سنی بیمارانی که فوت شدند 7/67 سال بود (27/16 SD=) که این رابطه از نظر آماری با (001/0 P<) معنادار بود. بیشترین بیماری زمینهای در بین بیماران به ترتیب، بیماریهای فشارخون 106 نفر (7/32 درصد)، دیابت102 نفر (5/31 درصد)، بیماریهای قلبی 71 نفر (9/21 درصد)، بیماری انسدادی مزمن ریه 23 نفر (1/7 درصد) و بیماری مزمن کلیه 17 نفر (2/5 درصد)، هیپوتیروئیدی 14 نفر (3/4 درصد) بود. از یافتههای جالب توجه در مطالعهی ما، وجود ارتباط بین بیماری زمینهای هایپوتیروئیدی با مرگ، در مبتلایان به کووید-19 بود که از نظر آماری بین دو گروه زنده مانده و فوت شده رابطه معناداری داشت (002/0 P=).همچنین از نظر وجود بیماری زمینه ای مزمن کلیوی نیز بین دو گروه به لحاظ آماری تفاوت معناداری وجود داشت ( 007/0 P=)؛ ولی از نظر سایر بیماریهای زمینهای بین افراد متوفی و بازمانده تفاوت معناداری مشاهده نشد (جدول 1).

جدول

شماره 1:

مقایسه

مشخصات

دموگرافیک

افراد متوف

بیماران

بازمانده مبتلا به کوو

ید

ویژگی

های

دموگرافیک

کل

(درصد)تعداد

زنده

(درصد)تعداد

فوت

شده

(درصد)تعداد

سطح

معناداری

جنس

مرد

175

(

)

108

(

7/61

)

(

3/38

)

626/0

زن

149

(

)

(

1/50

)

(

9/40

)

سیگار

(

)

(

7/9

)

(

5/5

)

277/0

اعتیاد

(

6/8

)

(

7/8

)

(

6/8

)

980/0

سابقه

مسافرت

(

7/11

)

(

)

(

7/4

)

030/0

بیماری

زم

ینه

ای

فاقد

بیماری

زمینه

ای

(

4/28

)

(

6/31

)

(

4/23

)

001/0

هایپرتانسیون

(7/32 )106

(

6/31

)

(

5/41

)

607/0

دیابت

(1/29 )102

(1/29 )57

(25/35)45

250/0

بیماری

مزمن

انسدادی

ریه

(1/7)23

(56/5)11

(4/9 )12

197/0

هیپوتیروئیدی

(3/4 )14

3/1 )3

(6/8 )11

002/0

آسیب

مزمن

کلیوی

(2/5 )17

(6/2 )5

(4/9)12

007/0

بدخیمی

(5/1 )5

(5/0)1

(1/3)4

062/0

پیوند

(6 )2

(5 )1

(8 )1

761/0

آرتریت

روماتوئید

(5/1 )5

(2 )4

(8 )1

369/0

بیماری

کرونری

قلب

(9/21)71

(4/22 )44

(1/21 )27

773/0

کا

اسکوئر

تجزیه و تحلیل چندمتغیره رگرسیون لجستیک نیز نشان داد که در بین فاکتورهای دموگرافیک سن و بیماریهای زمینهای آسیب کلیوی مزمن و هیپوتیروئیدی معنادار شدند (جدول 2).در مطالعهی حاضر علائم بالینی به 5 دسته علائم تنفسی، گوارشی، عصبی، قلبی و جسمی تقسیمبندی شدند. علائم تنفسی شامل تنگینفس، تاکیپنه، سرفهی خشک، سرفهی خلطدار، هموپتزی، آبریزش‌بینی بودند. همچنین علائم و عوارض گوارشی شامل بیاشتهایی، اختلال حس بویایی و چشایی، تهوع، استفراغ، یبوست، اسهال، درد شکم، سکسکه بودند. در بین علائم نورولوژی، سردرد، سرگیجه، اختلالات خواب، کاهش سطح هوشیاری، دلیریوم، تشنج و حوادث عروق مغزی به‌دست آمد. علائم قلبی نیز شامل درد و سنگینی قفسه سینه و آنفارکتوس میوکارد بود. در دسته علائم جسمی ضعف و بیحالی، بدندرد، گوشدرد، تب و لرز قرار گرفتند. در این بین تنگی‌نفس، ضعف و بیحالی، تب قبل و بعد از بستری، بین دو گروه متوفی و بازمانده از لحاظ آماری تفاوت معناداری مشاهده شد. سایر علائمی که در بین دوگروه متوفی و بازمانده با تفاوت معناداری مشاهده شد، شامل لرز، سرفه خشک، آبریزش‌بینی، دردشکم، اسهال، سردرد، سرگیجه و علائم قلبی بود. از 91 نفری که دچار علائم‌ قلبی شده‌بودند، 86 نفر (50/26 درصد‌ از کل) هنگام مراجعه درد قفسهی سینه داشتند و از این تعداد 66 نفر (70/76 درصد‌) زنده ماندند و20 نفر (30/23 درصد‌) فوت شدند. 5 نفر (5/1 درصد‌ازکل)، نیز دچار آنفارکتوسمیوکارد شده بودند که 4 نفر (80 درصد) آنها فوت شدند. در تجزیه و تحلیل چندمتغیره رگرسیون لجستیک از بین علائم تنفسی، سرفهی خشک، لرز و سردرد معنادار گردید (جدول 2).بیشترین اختلالات خواب در بین بیماران، بی‌خوابی بود. به‌طوری که 111 نفر (10/34 درصد‌ از کل) به دنبال ابتلا به کووید-19 دچار این عارضه شده‌بودند، که از این تعداد،61 نفر زنده (55 درصد‌) ماندند و50 نفر فوت (45 درصد‌) شدند. 5 نفر (5/1 درصد‌ از کل) نیز پرخوابی در دوران بستری در بیمارستان گزارش کردند که از این تعداد 4 نفر (80 درصد‌) زنده ماندند و 1 نفر (20 درصد‌) فوت شد. 208 نفر (2/64 درصد‌ از کل) هیچگونه اختلالات خوابی را عنوان نکرده ‌بودند که از این تعداد 131 نفر (63 درصد‌) زنده ماندند و 77 نفر (37 درصد‌) فوت شدند.

جدول

شماره 2:

مقایسه

ین

افراد متوف

و بازمانده مبتلا به کوو

ید

‌

از

نظر

تظاهرات

بالینی

سطح

معناداری

فوت شده

زنده

تعداد

علائم

بالینی

درصد

تعداد

درصد

تعداد

0003/0

6/48

4/54

112

206

تب قبل از

بستری

015/0

6/48

4/51

111

تب بعد از

بستری

004/0

7/45

3/54

108

199

لرز

001/0

2/48

8/51

102

197

سرفه

خشک

018/0

8/41

120

2/58

167

287

تنگی

نفس

043/0

6/22

4/77

آبریزش

بینی

010/0

1/26

9/73

درد

شکم

045/0

3/24

7/75

اسهال

001/0

5/22

5/77

102

سردرد

008/0

0/25

0/75

سرگیجه

015/0

4/42

115

6/57

156

271

ضعف

بی

حالی

001/0

37/26

62/73

علایم

قلبی

( درد قفسه

سینه،

آنفارکتوس )

کا

اسکوئر

در راستای مطالعه حاضر تستهای آزمایشگاهی در 8 دسته بررسی شدند که شمارش کامل سلولهای خونی، بیوشیمی (اوره و کراتینین)، الکترولیتها (سدیم، پتاسیم، کلسیم، منیزیم )، آزمایش فاکتورهای التهابی، آنالیز ادرار، تستهای انعقادی (pt، ptt)، تستهای عملکرد کبدی، مارکرهای قلبی و لاکتات دهیدروژناز را در برگرفتند. در این بین از نظر دو نوع الکترولیت بین دو گروه بازمانده و متوفی تفاوت معنادار وجود داشت. یکی از آنها وجود تفاوت معنادار بین مقدار سدیم پایه در بین دو گروه بود (001/0 P<)؛ ولی از نظر میزان سدیم در زمان ترخیص یا فوت تفاوت معناداری بین دو گروه وجود نداشت. همچنین متوسط میزان کلسیم در گروه زنده 75/8 و در گروه فوت شده 99/7 بود که به لحاظ آماری این تفاوت نیز معنادار بود (02/0 P=). اما از لحاظ سایر الکترولیتها بین دو گروه تفاوت معناداری مشاهده نشد. از دیگر یافتههای قابل توجه در این مطالعه وجود تفاوت معنادار در آزمایش پروتئینوری و همچنین هماچوری بین دو گروه زندهمانده و فوتشده بودند(001/0 P<). همچنین در بین آزمایشات خونی تفاوت‌ها در کاهش میزان لنفوسیت، افزایش نوتروفیلها، میزان توزیع گلبولهای قرمز

RDW کاهش سلولهای بازوفیل، مونوسیت و ائوزینوفیل

MIX معنادار گردید (001/0 P<) (جدول 3).تجزیه و تحلیل چندمتغیره رگرسیون لجستیک نیز نشان داد که در بین علائم خونی، کاهش لنفوسیتها معنادار گردید (0.993-0.939CI 95درصد‌). تجزیه و تحلیل چندمتغیره رگرسیون لجستیک نیز نشان داد که از بین یافتههای رادیولوژیک، عارضه کانسالیدیشن معنادار گردید (4.225-1.669CI 95درصد‌).

جدول

شماره3: مقا

یسه

ین

افراد متوف

و بازمانده مبتلا به کوو

ید

-19 از نظر

یافته

های

آزمایشگاهی

یافته

های

آزمایشگاهی

زنده

فوت شده

سطح معنادار

یانگین

انحراف

معیار

یانگین

انحراف

معیار

LDH

720.71

422.52

1206.31

1363.07

0.009

BUN1

21.65

18.17

28.69

20.44

0.001

BUN2

28.47

27.21

49.81

38.73

0.001

Na1

140.35

3.72

138.76

4.56

0.001

8.75

1.86

7.99

1.13

0.002

WBC2

8.40

4.32

14.46

15.67

0.001

RBC2

4.21

0.65

3.68

0.82

0.001

HCT2

35.43

5.64

33.43

6.90

0.037

MCV1

85.84

6.44

88.76

8.07

0.001

MCV2

85.94

6.37

93.18

28.98

0.028

MCH1

29.54

2.85

30.31

3.30

0.029

MCHC2

35.24

8.40

33.40

1.92

0.046

Mix1

5.18

3.16

4.36

3.01

0.026

Mix2

6.52

3.86

4.25

2.38

0.001

Lymphocyte1

22.48

12.30

17.58

11.66

0.001

Lymphocyte2

20.24

11.97

9.83

7.85

0.001

Neutrophil1

72.13

13.12

76.95

13.80

0.002

Neutrophil2

70.73

13.55

83.68

12.11

0.001

RDW1

13.81

2.29

14.68

2.34

0.001

RDW2

14.31

2.42

16.00

2.46

0.001

ESR1

38.62

21.99

44.93

23.11

0.001

CRP1

26.58

21.56

40.21

23.89

0.001

CRP2

23.04

20.77

46.75

23.95

0.001

بحثتظاهرات بالینی عفونت کرونا ویروس 2019 مشابه با سندرم حاد تنفسی سارسکووید-2

SARS-CoV-2 است ADDIN EN.CITE <EndNote><Cite><Author>Yang</Author><Year>2020</Year><RecNum>144</RecNum><DisplayText>(23, 24)</DisplayText><record><rec-number>144</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">144</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Yang, Wenjie</author><author>Cao, Qiqi</author><author>Qin, Le</author><author>Wang, Xiaoyang</author><author>Cheng, Zenghui</author><author>Pan, Ashan</author><author>Dai, Jianyi</author><author>Sun, Qingfeng</author><author>Zhao, Fengquan</author><author>Qu, Jieming</author></authors></contributors><titles><title>Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city, Zhejiang, China</title><secondary-title>Journal of Infection</secondary-title></titles><periodical><full-title>Journal of Infection</full-title></periodical><dates><year>2020</year></dates><isbn>0163-4453</isbn><urls></urls></record></Cite><Cite><Author>Brüssow</Author><Year>2020</Year><RecNum>145</RecNum><record><rec-number>145</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">145</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Brüssow, Harald</author></authors></contributors><titles><title>The novel coronavirus–a snapshot of current knowledge</title><secondary-title>Microbial Biotechnology</secondary-title></titles><periodical><full-title>Microbial Biotechnology</full-title></periodical><pages>607-612</pages><volume>13</volume><number>3</number><dates><year>2020</year></dates><isbn>1751-7915</isbn><urls></urls></record></Cite></EndNote>(23, 24). در مطالعه حاضر پس از آنالیز دادهها سه علامت شایع به ترتیب شامل تنگینفس، ضعف و بی‌حالی و بیاشتهایی بود؛ اما در تجزیه و تحلیل چندمتغیره رگرسیون لجستیک سرفهی خشک، سردرد و لرز معنادار گردید

. بیماران مبتلا به نوع شدید کووید-19 ممکن است به دلیل بروز هیپوکسمی، آسیب میوکارد را تجربه کرده و علائم درد قفسه‌سینه را بروز دهند. بنابراین، بایستی به بیماران کووید-19 که دارای علائم تنگینفس، دردقفسهی سینه و سایر علائم قلبی در اوایل شروع بیماری هستند، توجه بیشتری شود PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5MaXBwaTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT43NDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTEpPC9EaXNwbGF5VGV4dD48cmVjb3JkPjxy ZWMtbnVtYmVyPjc0PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBkYi1p ZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj43NDwva2V5PjwvZm9yZWln bi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29u dHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+TGlwcGksIEcuPC9hdXRob3I+PGF1dGhvcj5Xb25n LCBKLjwvYXV0aG9yPjxhdXRob3I+SGVucnksIEIuIE0uPC9hdXRob3I+PC9hdXRob3JzPjwvY29u dHJpYnV0b3JzPjxhdXRoLWFkZHJlc3M+U2VjdGlvbiBvZiBDbGluaWNhbCBCaW9jaGVtaXN0cnks IERlcGFydG1lbnQgb2YgTmV1cm9zY2llbmNlLCBCaW9tZWRpY2luZSBhbmQgTW92ZW1lbnQsIFVu aXZlcnNpdHkgb2YgVmVyb25hLCBWZXJvbmEsIEl0YWx5LiBnaXVzZXBwZS5saXBwaUB1bml2ci5p dCYjeEQ7Q29sbGVnZSBvZiBNZWRpY2luZSwgU1VOWSBEb3duc3RhdGUgSGVhbHRoIFNjaWVuY2Vz IFVuaXZlcnNpdHksIE5ldyBZb3JrLCBVbml0ZWQgU3RhdGVzJiN4RDtDYXJkaWFjIEludGVuc2l2 ZSBDYXJlIFVuaXQsIFRoZSBIZWFydCBJbnN0aXR1dGUsIENpbmNpbm5hdGkgQ2hpbGRyZW7igJlz IEhvc3BpdGFsIE1lZGljYWwgQ2VudGVyLCBDaW5jaW5uYXRpLCBPaGlvLCBVbml0ZWQgU3RhdGVz PC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+SHlwZXJ0ZW5zaW9uIGluIHBhdGllbnRzIHdp dGggY29yb25hdmlydXMgZGlzZWFzZSAyMDE5IChDT1ZJRC0xOSk6IGEgcG9vbGVkIGFuYWx5c2lz PC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPlBvbCBBcmNoIEludGVybiBNZWQ8L3NlY29uZGFyeS10 aXRsZT48YWx0LXRpdGxlPlBvbGlzaCBhcmNoaXZlcyBvZiBpbnRlcm5hbCBtZWRpY2luZTwvYWx0 LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBBcmNoIEludGVybiBN ZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50ZXJuYWwgbWVkaWNp bmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBB cmNoIEludGVybiBNZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50 ZXJuYWwgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdlcz4zMDQtMzA5PC9w YWdlcz48dm9sdW1lPjEzMDwvdm9sdW1lPjxudW1iZXI+NDwvbnVtYmVyPjxlZGl0aW9uPjIwMjAv MDQvMDI8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+ QmV0YWNvcm9uYXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPipDb3JvbmF2aXJ1cyBJbmZlY3Rpb25z L2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29y ZD48a2V5d29yZD4qSHlwZXJ0ZW5zaW9uL2NvbXBsaWNhdGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+ TW9ydGFsaXR5L3RyZW5kczwva2V5d29yZD48a2V5d29yZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxr ZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3Jk PjxrZXl3b3JkPlByb2dub3Npczwva2V5d29yZD48a2V5d29yZD5SaXNrIEZhY3RvcnM8L2tleXdv cmQ+PGtleXdvcmQ+U2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48L2tleXdvcmRz PjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+QXByIDMwPC9kYXRlPjwv cHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MDAzMi0zNzcyPC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMy MjMxMTcxPC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1u dW0+MTAuMjA0NTIvcGFtdy4xNTI3MjwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1k YXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPgB= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5MaXBwaTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT43NDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTEpPC9EaXNwbGF5VGV4dD48cmVjb3JkPjxy ZWMtbnVtYmVyPjc0PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBkYi1p ZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj43NDwva2V5PjwvZm9yZWln bi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29u dHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+TGlwcGksIEcuPC9hdXRob3I+PGF1dGhvcj5Xb25n LCBKLjwvYXV0aG9yPjxhdXRob3I+SGVucnksIEIuIE0uPC9hdXRob3I+PC9hdXRob3JzPjwvY29u dHJpYnV0b3JzPjxhdXRoLWFkZHJlc3M+U2VjdGlvbiBvZiBDbGluaWNhbCBCaW9jaGVtaXN0cnks IERlcGFydG1lbnQgb2YgTmV1cm9zY2llbmNlLCBCaW9tZWRpY2luZSBhbmQgTW92ZW1lbnQsIFVu aXZlcnNpdHkgb2YgVmVyb25hLCBWZXJvbmEsIEl0YWx5LiBnaXVzZXBwZS5saXBwaUB1bml2ci5p dCYjeEQ7Q29sbGVnZSBvZiBNZWRpY2luZSwgU1VOWSBEb3duc3RhdGUgSGVhbHRoIFNjaWVuY2Vz IFVuaXZlcnNpdHksIE5ldyBZb3JrLCBVbml0ZWQgU3RhdGVzJiN4RDtDYXJkaWFjIEludGVuc2l2 ZSBDYXJlIFVuaXQsIFRoZSBIZWFydCBJbnN0aXR1dGUsIENpbmNpbm5hdGkgQ2hpbGRyZW7igJlz IEhvc3BpdGFsIE1lZGljYWwgQ2VudGVyLCBDaW5jaW5uYXRpLCBPaGlvLCBVbml0ZWQgU3RhdGVz PC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+SHlwZXJ0ZW5zaW9uIGluIHBhdGllbnRzIHdp dGggY29yb25hdmlydXMgZGlzZWFzZSAyMDE5IChDT1ZJRC0xOSk6IGEgcG9vbGVkIGFuYWx5c2lz PC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPlBvbCBBcmNoIEludGVybiBNZWQ8L3NlY29uZGFyeS10 aXRsZT48YWx0LXRpdGxlPlBvbGlzaCBhcmNoaXZlcyBvZiBpbnRlcm5hbCBtZWRpY2luZTwvYWx0 LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBBcmNoIEludGVybiBN ZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50ZXJuYWwgbWVkaWNp bmU8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlBvbCBB cmNoIEludGVybiBNZWQ8L2Z1bGwtdGl0bGU+PGFiYnItMT5Qb2xpc2ggYXJjaGl2ZXMgb2YgaW50 ZXJuYWwgbWVkaWNpbmU8L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdlcz4zMDQtMzA5PC9w YWdlcz48dm9sdW1lPjEzMDwvdm9sdW1lPjxudW1iZXI+NDwvbnVtYmVyPjxlZGl0aW9uPjIwMjAv MDQvMDI8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+ QmV0YWNvcm9uYXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPipDb3JvbmF2aXJ1cyBJbmZlY3Rpb25z L2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29y ZD48a2V5d29yZD4qSHlwZXJ0ZW5zaW9uL2NvbXBsaWNhdGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+ TW9ydGFsaXR5L3RyZW5kczwva2V5d29yZD48a2V5d29yZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxr ZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMvbW9ydGFsaXR5PC9rZXl3b3Jk PjxrZXl3b3JkPlByb2dub3Npczwva2V5d29yZD48a2V5d29yZD5SaXNrIEZhY3RvcnM8L2tleXdv cmQ+PGtleXdvcmQ+U2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwva2V5d29yZD48L2tleXdvcmRz PjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+QXByIDMwPC9kYXRlPjwv cHViLWRhdGVzPjwvZGF0ZXM+PGlzYm4+MDAzMi0zNzcyPC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMy MjMxMTcxPC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1u dW0+MTAuMjA0NTIvcGFtdy4xNTI3MjwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1k YXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPgB= ADDIN EN.CITE.DATA (11).در مطالعهی حاضر نیز از نظر بروز علائم قلبی در دو گروه متوفی و بازمانده تفاوت معناداری وجود داشت. نتایج مطالعهی آنجلی و همکاران نیز نشان داد ناهنجاریهای الکتروکاردیوگرام در حین بستری در مبتلایان به کووید-19 طیف گستردهای از عوارض قلبی-عروقی را نشان دادهاند، که به صورت دیررس شروع شده و به موازات ناهنجاریهای ریوی پیشرفت نکرده و حتی ممکن است پس از منفی شدن نمونه سواپ حلق نیز رخ دهد ADDIN EN.CITE <EndNote><Cite><Author>Angeli</Author><Year>2020</Year><RecNum>75</RecNum><DisplayText>(25)</DisplayText><record><rec-number>75</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">75</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Angeli, Fabio</author><author>Spanevello, Antonio</author><author>De Ponti, Roberto</author><author>Visca, Dina</author><author>Marazzato, Jacopo</author><author>Palmiotto, Giulia</author><author>Feci, Davide</author><author>Reboldi, Gianpaolo</author><author>Fabbri, Leonardo M.</author><author>Verdecchia, Paolo</author></authors></contributors><titles><title>Electrocardiographic features of patients with COVID-19 pneumonia</title><secondary-title>European Journal of Internal Medicine</secondary-title></titles><periodical><full-title>European Journal of Internal Medicine</full-title></periodical><pages>101-106</pages><volume>78</volume><dates><year>2020</year></dates><publisher>Elsevier</publisher><isbn>0953-6205</isbn><urls><related-urls><url>https://doi.org/10.1016/j.ejim.2020.06.015</url></related-urls></urls><electronic-resource-num>10.1016/j.ejim.2020.06.015</electronic-resource-num><access-date>2020/11/23</access-date></record></Cite></EndNote>(25). در مطالعهی ما همچنین بیماران متوفی نسبت به بازماندگان مسنتر بوده و از لحاظ سن بین دو گروه بازمانده و متوفی، تفاوت معناداری وجود داشت. این یافته با مطالعه ژو و همکاران همسو بود PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjI2PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxMCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+MjY8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjI2PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaG91LCBGLjwvYXV0aG9yPjxhdXRob3I+WXUsIFQu PC9hdXRob3I+PGF1dGhvcj5EdSwgUi48L2F1dGhvcj48YXV0aG9yPkZhbiwgRy48L2F1dGhvcj48 YXV0aG9yPkxpdSwgWS48L2F1dGhvcj48YXV0aG9yPkxpdSwgWi48L2F1dGhvcj48YXV0aG9yPlhp YW5nLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgWS48L2F1dGhvcj48YXV0aG9yPlNvbmcsIEIu PC9hdXRob3I+PGF1dGhvcj5HdSwgWC48L2F1dGhvcj48YXV0aG9yPkd1YW4sIEwuPC9hdXRob3I+ PGF1dGhvcj5XZWksIFkuPC9hdXRob3I+PGF1dGhvcj5MaSwgSC48L2F1dGhvcj48YXV0aG9yPld1 LCBYLjwvYXV0aG9yPjxhdXRob3I+WHUsIEouPC9hdXRob3I+PGF1dGhvcj5UdSwgUy48L2F1dGhv cj48YXV0aG9yPlpoYW5nLCBZLjwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgSC48L2F1dGhvcj48YXV0 aG9yPkNhbywgQi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVz cz5EZXBhcnRtZW50IG9mIFB1bG1vbmFyeSBhbmQgQ3JpdGljYWwgQ2FyZSBNZWRpY2luZSwgQ2Vu dGVyIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIFJlc3BpcmF0b3J5IERpc2Vhc2VzLCBJbnN0aXR1dGUgb2YgUmVzcGlyYXRvcnkg TWVkaWNpbmUsIENoaW5lc2UgQWNhZGVteSBvZiBNZWRpY2FsIFNjaWVuY2VzLCBQZWtpbmcgVW5p b24gTWVkaWNhbCBDb2xsZWdlLCBCZWlqaW5nLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgVHVi ZXJjdWxvc2lzIGFuZCBSZXNwaXJhdG9yeSBEaXNlYXNlLCBKaW55aW50YW4gSG9zcGl0YWwsIFd1 aGFuLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJl IE1lZGljaW5lLCBXdWhhbiBQdWxtb25hcnkgSG9zcGl0YWwsIFd1aGFuLCBDaGluYS4mI3hEO0Rl cGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJlIE1lZGljaW5lLCBDZW50ZXIg b2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRl ciBmb3IgUmVzcGlyYXRvcnkgRGlzZWFzZXMsIEluc3RpdHV0ZSBvZiBSZXNwaXJhdG9yeSBNZWRp Y2luZSwgQ2hpbmVzZSBBY2FkZW15IG9mIE1lZGljYWwgU2NpZW5jZXMsIFBla2luZyBVbmlvbiBN ZWRpY2FsIENvbGxlZ2UsIEJlaWppbmcsIENoaW5hOyBJbnN0aXR1dGUgb2YgQ2xpbmljYWwgTWVk aWNhbCBTY2llbmNlcywgQ2hpbmEtSmFwYW4gRnJpZW5kc2hpcCBIb3NwaXRhbCwgQmVpamluZywg Q2hpbmEuJiN4RDtEZXBhcnRtZW50IG9mIENsaW5pY2FsIExhYm9yYXRvcnksIEppbnlpbnRhbiBI b3NwaXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBQdWxtb25hcnkgYW5kIENy aXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgTmF0 aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJhdG9yeSBEaXNlYXNlcywg SW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNlIEFjYWRlbXkgb2YgTWVk aWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVnZSwgQmVpamluZywgQ2hp bmE7IERlcGFydG1lbnQgb2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIENhcGl0YWwgTWVkaWNhbCBV bml2ZXJzaXR5LCBCZWlqaW5nLCBDaGluYS4mI3hEO0dDUCBDZW50ZXIsIEppbnlpbnRhbiBIb3Nw aXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7VHNpbmdodWEgVW5pdmVyc2l0eSBTY2hvb2wgb2YgTWVk aWNpbmUsIEJlaWppbmcsIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBUdWJlcmN1bG9zaXMgYW5k IFJlc3BpcmF0b3J5IERpc2Vhc2UsIEppbnlpbnRhbiBIb3NwaXRhbCwgV3VoYW4sIENoaW5hLiBF bGVjdHJvbmljIGFkZHJlc3M6IDI3MTY2Mzc5NDdAcXEuY29tLiYjeEQ7RGVwYXJ0bWVudCBvZiBQ dWxtb25hcnkgYW5kIENyaXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9y eSBNZWRpY2luZSwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJh dG9yeSBEaXNlYXNlcywgSW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNl IEFjYWRlbXkgb2YgTWVkaWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVn ZSwgQmVpamluZywgQ2hpbmE7IERlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBD YXJlIE1lZGljaW5lLCBDaGluYS1KYXBhbiBGcmllbmRzaGlwIEhvc3BpdGFsLCBCZWlqaW5nLCBD aGluYTsgRGVwYXJ0bWVudCBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgQ2FwaXRhbCBNZWRpY2Fs IFVuaXZlcnNpdHksIEJlaWppbmcsIENoaW5hOyBUc2luZ2h1YSBVbml2ZXJzaXR5IFNjaG9vbCBv ZiBNZWRpY2luZSwgQmVpamluZywgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2FvYmluX2Jl bkAxNjMuY29tLjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2FsIGNvdXJzZSBh bmQgcmlzayBmYWN0b3JzIGZvciBtb3J0YWxpdHkgb2YgYWR1bHQgaW5wYXRpZW50cyB3aXRoIENP VklELTE5IGluIFd1aGFuLCBDaGluYTogYSByZXRyb3NwZWN0aXZlIGNvaG9ydCBzdHVkeTwvdGl0 bGU+PHNlY29uZGFyeS10aXRsZT5MYW5jZXQ8L3NlY29uZGFyeS10aXRsZT48YWx0LXRpdGxlPkxh bmNldCAoTG9uZG9uLCBFbmdsYW5kKTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkxhbmNldDwvZnVsbC10aXRsZT48YWJici0xPkxhbmNldCAoTG9uZG9uLCBFbmds YW5kKTwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TGFu Y2V0PC9mdWxsLXRpdGxlPjxhYmJyLTE+TGFuY2V0IChMb25kb24sIEVuZ2xhbmQpPC9hYmJyLTE+ PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+MTA1NC0xMDYyPC9wYWdlcz48dm9sdW1lPjM5NTwvdm9s dW1lPjxudW1iZXI+MTAyMjk8L251bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzE1PC9lZGl0aW9uPjxr ZXl3b3Jkcz48a2V5d29yZD5BZG9sZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3 b3JkPjxrZXl3b3JkPkFnZSBGYWN0b3JzPC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+ PGtleXdvcmQ+QWdlZCwgODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtleXdvcmQ+QmV0YWNvcm9uYXZp cnVzPC9rZXl3b3JkPjxrZXl3b3JkPkNhcmRpb3Zhc2N1bGFyIERpc2Vhc2VzL2NvbXBsaWNhdGlv bnM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdvcmQ+Q2xpbmljYWwgTGFi b3JhdG9yeSBUZWNobmlxdWVzPC9rZXl3b3JkPjxrZXl3b3JkPkNvaG9ydCBTdHVkaWVzPC9rZXl3 b3JkPjxrZXl3b3JkPkNvbW9yYmlkaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIElu ZmVjdGlvbnMvY29tcGxpY2F0aW9ucy9kaWFnbm9zaXMvKm1vcnRhbGl0eTwva2V5d29yZD48a2V5 d29yZD5EaWFiZXRlcyBDb21wbGljYXRpb25zPC9rZXl3b3JkPjxrZXl3b3JkPkRpc2Vhc2UgUHJv Z3Jlc3Npb248L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkZpYnJp biBGaWJyaW5vZ2VuIERlZ3JhZGF0aW9uIFByb2R1Y3RzL2FuYWx5c2lzPC9rZXl3b3JkPjxrZXl3 b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5IeXBlcnRlbnNpb24vY29tcGxpY2F0aW9uczwv a2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3b3JkPk1pZGRsZSBBZ2VkPC9rZXl3 b3JkPjxrZXl3b3JkPk1vcnRhbGl0eS90cmVuZHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk9yZ2FuIER5 c2Z1bmN0aW9uIFNjb3Jlczwva2V5d29yZD48a2V5d29yZD5QYW5kZW1pY3M8L2tleXdvcmQ+PGtl eXdvcmQ+KlBhdGllbnQgQ2FyZSBQbGFubmluZzwva2V5d29yZD48a2V5d29yZD5QYXRpZW50IElz b2xhdGlvbjwva2V5d29yZD48a2V5d29yZD5QbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMv ZGlhZ25vc2lzLyptb3J0YWxpdHk8L2tleXdvcmQ+PGtleXdvcmQ+UHJvZ25vc2lzPC9rZXl3b3Jk PjxrZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD4qUmlzayBB c3Nlc3NtZW50L21ldGhvZHM8L2tleXdvcmQ+PGtleXdvcmQ+UmlzayBGYWN0b3JzPC9rZXl3b3Jk PjxrZXl3b3JkPllvdW5nIEFkdWx0PC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIw MjA8L3llYXI+PHB1Yi1kYXRlcz48ZGF0ZT5NYXIgMjg8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRl cz48aXNibj4wMTQwLTY3MzYgKFByaW50KSYjeEQ7MDE0MC02NzM2PC9pc2JuPjxhY2Nlc3Npb24t bnVtPjMyMTcxMDc2PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM3Mjcw NjI3PC9jdXN0b20yPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L3MwMTQwLTY3MzYo MjApMzA1NjYtMzwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1wcm92 aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFn ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjI2PC9SZWNOdW0+PERpc3BsYXlUZXh0PigxMCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+MjY8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjI2PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaG91LCBGLjwvYXV0aG9yPjxhdXRob3I+WXUsIFQu PC9hdXRob3I+PGF1dGhvcj5EdSwgUi48L2F1dGhvcj48YXV0aG9yPkZhbiwgRy48L2F1dGhvcj48 YXV0aG9yPkxpdSwgWS48L2F1dGhvcj48YXV0aG9yPkxpdSwgWi48L2F1dGhvcj48YXV0aG9yPlhp YW5nLCBKLjwvYXV0aG9yPjxhdXRob3I+V2FuZywgWS48L2F1dGhvcj48YXV0aG9yPlNvbmcsIEIu PC9hdXRob3I+PGF1dGhvcj5HdSwgWC48L2F1dGhvcj48YXV0aG9yPkd1YW4sIEwuPC9hdXRob3I+ PGF1dGhvcj5XZWksIFkuPC9hdXRob3I+PGF1dGhvcj5MaSwgSC48L2F1dGhvcj48YXV0aG9yPld1 LCBYLjwvYXV0aG9yPjxhdXRob3I+WHUsIEouPC9hdXRob3I+PGF1dGhvcj5UdSwgUy48L2F1dGhv cj48YXV0aG9yPlpoYW5nLCBZLjwvYXV0aG9yPjxhdXRob3I+Q2hlbiwgSC48L2F1dGhvcj48YXV0 aG9yPkNhbywgQi48L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVz cz5EZXBhcnRtZW50IG9mIFB1bG1vbmFyeSBhbmQgQ3JpdGljYWwgQ2FyZSBNZWRpY2luZSwgQ2Vu dGVyIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBOYXRpb25hbCBDbGluaWNhbCBSZXNlYXJjaCBD ZW50ZXIgZm9yIFJlc3BpcmF0b3J5IERpc2Vhc2VzLCBJbnN0aXR1dGUgb2YgUmVzcGlyYXRvcnkg TWVkaWNpbmUsIENoaW5lc2UgQWNhZGVteSBvZiBNZWRpY2FsIFNjaWVuY2VzLCBQZWtpbmcgVW5p b24gTWVkaWNhbCBDb2xsZWdlLCBCZWlqaW5nLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgVHVi ZXJjdWxvc2lzIGFuZCBSZXNwaXJhdG9yeSBEaXNlYXNlLCBKaW55aW50YW4gSG9zcGl0YWwsIFd1 aGFuLCBDaGluYS4mI3hEO0RlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJl IE1lZGljaW5lLCBXdWhhbiBQdWxtb25hcnkgSG9zcGl0YWwsIFd1aGFuLCBDaGluYS4mI3hEO0Rl cGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBDYXJlIE1lZGljaW5lLCBDZW50ZXIg b2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRl ciBmb3IgUmVzcGlyYXRvcnkgRGlzZWFzZXMsIEluc3RpdHV0ZSBvZiBSZXNwaXJhdG9yeSBNZWRp Y2luZSwgQ2hpbmVzZSBBY2FkZW15IG9mIE1lZGljYWwgU2NpZW5jZXMsIFBla2luZyBVbmlvbiBN ZWRpY2FsIENvbGxlZ2UsIEJlaWppbmcsIENoaW5hOyBJbnN0aXR1dGUgb2YgQ2xpbmljYWwgTWVk aWNhbCBTY2llbmNlcywgQ2hpbmEtSmFwYW4gRnJpZW5kc2hpcCBIb3NwaXRhbCwgQmVpamluZywg Q2hpbmEuJiN4RDtEZXBhcnRtZW50IG9mIENsaW5pY2FsIExhYm9yYXRvcnksIEppbnlpbnRhbiBI b3NwaXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBQdWxtb25hcnkgYW5kIENy aXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgTmF0 aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJhdG9yeSBEaXNlYXNlcywg SW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNlIEFjYWRlbXkgb2YgTWVk aWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVnZSwgQmVpamluZywgQ2hp bmE7IERlcGFydG1lbnQgb2YgUmVzcGlyYXRvcnkgTWVkaWNpbmUsIENhcGl0YWwgTWVkaWNhbCBV bml2ZXJzaXR5LCBCZWlqaW5nLCBDaGluYS4mI3hEO0dDUCBDZW50ZXIsIEppbnlpbnRhbiBIb3Nw aXRhbCwgV3VoYW4sIENoaW5hLiYjeEQ7VHNpbmdodWEgVW5pdmVyc2l0eSBTY2hvb2wgb2YgTWVk aWNpbmUsIEJlaWppbmcsIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBUdWJlcmN1bG9zaXMgYW5k IFJlc3BpcmF0b3J5IERpc2Vhc2UsIEppbnlpbnRhbiBIb3NwaXRhbCwgV3VoYW4sIENoaW5hLiBF bGVjdHJvbmljIGFkZHJlc3M6IDI3MTY2Mzc5NDdAcXEuY29tLiYjeEQ7RGVwYXJ0bWVudCBvZiBQ dWxtb25hcnkgYW5kIENyaXRpY2FsIENhcmUgTWVkaWNpbmUsIENlbnRlciBvZiBSZXNwaXJhdG9y eSBNZWRpY2luZSwgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBSZXNwaXJh dG9yeSBEaXNlYXNlcywgSW5zdGl0dXRlIG9mIFJlc3BpcmF0b3J5IE1lZGljaW5lLCBDaGluZXNl IEFjYWRlbXkgb2YgTWVkaWNhbCBTY2llbmNlcywgUGVraW5nIFVuaW9uIE1lZGljYWwgQ29sbGVn ZSwgQmVpamluZywgQ2hpbmE7IERlcGFydG1lbnQgb2YgUHVsbW9uYXJ5IGFuZCBDcml0aWNhbCBD YXJlIE1lZGljaW5lLCBDaGluYS1KYXBhbiBGcmllbmRzaGlwIEhvc3BpdGFsLCBCZWlqaW5nLCBD aGluYTsgRGVwYXJ0bWVudCBvZiBSZXNwaXJhdG9yeSBNZWRpY2luZSwgQ2FwaXRhbCBNZWRpY2Fs IFVuaXZlcnNpdHksIEJlaWppbmcsIENoaW5hOyBUc2luZ2h1YSBVbml2ZXJzaXR5IFNjaG9vbCBv ZiBNZWRpY2luZSwgQmVpamluZywgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2FvYmluX2Jl bkAxNjMuY29tLjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2FsIGNvdXJzZSBh bmQgcmlzayBmYWN0b3JzIGZvciBtb3J0YWxpdHkgb2YgYWR1bHQgaW5wYXRpZW50cyB3aXRoIENP VklELTE5IGluIFd1aGFuLCBDaGluYTogYSByZXRyb3NwZWN0aXZlIGNvaG9ydCBzdHVkeTwvdGl0 bGU+PHNlY29uZGFyeS10aXRsZT5MYW5jZXQ8L3NlY29uZGFyeS10aXRsZT48YWx0LXRpdGxlPkxh bmNldCAoTG9uZG9uLCBFbmdsYW5kKTwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkxhbmNldDwvZnVsbC10aXRsZT48YWJici0xPkxhbmNldCAoTG9uZG9uLCBFbmds YW5kKTwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TGFu Y2V0PC9mdWxsLXRpdGxlPjxhYmJyLTE+TGFuY2V0IChMb25kb24sIEVuZ2xhbmQpPC9hYmJyLTE+ PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+MTA1NC0xMDYyPC9wYWdlcz48dm9sdW1lPjM5NTwvdm9s dW1lPjxudW1iZXI+MTAyMjk8L251bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzE1PC9lZGl0aW9uPjxr ZXl3b3Jkcz48a2V5d29yZD5BZG9sZXNjZW50PC9rZXl3b3JkPjxrZXl3b3JkPkFkdWx0PC9rZXl3 b3JkPjxrZXl3b3JkPkFnZSBGYWN0b3JzPC9rZXl3b3JkPjxrZXl3b3JkPkFnZWQ8L2tleXdvcmQ+ PGtleXdvcmQ+QWdlZCwgODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtleXdvcmQ+QmV0YWNvcm9uYXZp cnVzPC9rZXl3b3JkPjxrZXl3b3JkPkNhcmRpb3Zhc2N1bGFyIERpc2Vhc2VzL2NvbXBsaWNhdGlv bnM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdvcmQ+Q2xpbmljYWwgTGFi b3JhdG9yeSBUZWNobmlxdWVzPC9rZXl3b3JkPjxrZXl3b3JkPkNvaG9ydCBTdHVkaWVzPC9rZXl3 b3JkPjxrZXl3b3JkPkNvbW9yYmlkaXR5PC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIElu ZmVjdGlvbnMvY29tcGxpY2F0aW9ucy9kaWFnbm9zaXMvKm1vcnRhbGl0eTwva2V5d29yZD48a2V5 d29yZD5EaWFiZXRlcyBDb21wbGljYXRpb25zPC9rZXl3b3JkPjxrZXl3b3JkPkRpc2Vhc2UgUHJv Z3Jlc3Npb248L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkZpYnJp biBGaWJyaW5vZ2VuIERlZ3JhZGF0aW9uIFByb2R1Y3RzL2FuYWx5c2lzPC9rZXl3b3JkPjxrZXl3 b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5IeXBlcnRlbnNpb24vY29tcGxpY2F0aW9uczwv a2V5d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3b3JkPk1pZGRsZSBBZ2VkPC9rZXl3 b3JkPjxrZXl3b3JkPk1vcnRhbGl0eS90cmVuZHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk9yZ2FuIER5 c2Z1bmN0aW9uIFNjb3Jlczwva2V5d29yZD48a2V5d29yZD5QYW5kZW1pY3M8L2tleXdvcmQ+PGtl eXdvcmQ+KlBhdGllbnQgQ2FyZSBQbGFubmluZzwva2V5d29yZD48a2V5d29yZD5QYXRpZW50IElz b2xhdGlvbjwva2V5d29yZD48a2V5d29yZD5QbmV1bW9uaWEsIFZpcmFsL2NvbXBsaWNhdGlvbnMv ZGlhZ25vc2lzLyptb3J0YWxpdHk8L2tleXdvcmQ+PGtleXdvcmQ+UHJvZ25vc2lzPC9rZXl3b3Jk PjxrZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD4qUmlzayBB c3Nlc3NtZW50L21ldGhvZHM8L2tleXdvcmQ+PGtleXdvcmQ+UmlzayBGYWN0b3JzPC9rZXl3b3Jk PjxrZXl3b3JkPllvdW5nIEFkdWx0PC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIw MjA8L3llYXI+PHB1Yi1kYXRlcz48ZGF0ZT5NYXIgMjg8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRl cz48aXNibj4wMTQwLTY3MzYgKFByaW50KSYjeEQ7MDE0MC02NzM2PC9pc2JuPjxhY2Nlc3Npb24t bnVtPjMyMTcxMDc2PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM3Mjcw NjI3PC9jdXN0b20yPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L3MwMTQwLTY3MzYo MjApMzA1NjYtMzwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1wcm92 aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFn ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE.DATA (10)؛ اعتقاد بر این است که این ارتباط با ضعف عملکرد سیستم ایمنی در افراد مسن مرتبط است ADDIN EN.CITE <EndNote><Cite><Author>Wu</Author><Year>2020</Year><RecNum>76</RecNum><DisplayText>(26)</DisplayText><record><rec-number>76</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">76</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Wu, J.</author><author>Li, W.</author><author>Shi, X.</author><author>Chen, Z.</author><author>Jiang, B.</author><author>Liu, J.</author><author>Wang, D.</author><author>Liu, C.</author><author>Meng, Y.</author><author>Cui, L.</author><author>Yu, J.</author><author>Cao, H.</author><author>Li, L.</author></authors></contributors><titles><title>Early antiviral treatment contributes to alleviate the severity and improve the prognosis of patients with novel coronavirus disease (COVID-19)</title><secondary-title>Journal of Internal Medicine</secondary-title></titles><periodical><full-title>Journal of Internal Medicine</full-title></periodical><pages>128-138</pages><volume>288</volume><number>1</number><keywords><keyword>severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)</keyword><keyword>coronavirus disease-19 (COVID-19)</keyword><keyword>antiviral treatment</keyword><keyword>disease progression</keyword><keyword>prognosis</keyword></keywords><dates><year>2020</year><pub-dates><date>2020/07/01</date></pub-dates></dates><publisher>John Wiley & Sons, Ltd</publisher><isbn>0954-6820</isbn><work-type>https://doi.org/10.1111/joim.13063</work-type><urls><related-urls><url>https://doi.org/10.1111/joim.13063</url></related-urls></urls><electronic-resource-num>https://doi.org/10.1111/joim.13063</electronic-resource-num><access-date>2020/11/23</access-date></record></Cite></EndNote>(26). از نظر جنسیت در مطالعات مختلف نتایج متفاوتی گزارش شده‌است. در مطالعهی حاضر از نظر جنسیت تفاوتی بین دو گروه وجود نداشت. این یافته با نتایج مطالعهی آگاروال و همکاران همسو بود PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5BZ2dhcndhbDwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+ PFJlY051bT41MzwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMjcpPC9EaXNwbGF5VGV4dD48cmVjb3Jk PjxyZWMtbnVtYmVyPjUzPC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBk Yi1pZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj41Mzwva2V5PjwvZm9y ZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48 Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+QWdnYXJ3YWwsIFMuPC9hdXRob3I+PGF1dGhv cj5HYXJjaWEtVGVsbGVzLCBOLjwvYXV0aG9yPjxhdXRob3I+QWdnYXJ3YWwsIEcuPC9hdXRob3I+ PGF1dGhvcj5MYXZpZSwgQy48L2F1dGhvcj48YXV0aG9yPkxpcHBpLCBHLjwvYXV0aG9yPjxhdXRo b3I+SGVucnksIEIuIE0uPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjxhdXRoLWFk ZHJlc3M+RGl2aXNpb24gb2YgQ2FyZGlvbG9neSwgRGVwYXJ0bWVudCBvZiBNZWRpY2luZSwgVW5p dHlQb2ludCBDbGluaWMsIDEyMTUgUGxlYXNhbnQgU3RyZWV0LCBTdWl0ZSA0MTQsIERlcyBNb2lu ZXMsIElBIDUwMzIzLCBVU0EuJiN4RDtEZXBhcnRtZW50IG9mIE1lZGljaW5lLCBVbml0eVBvaW50 IENsaW5pYywgRGVzIE1vaW5lcywgSUEsIFVTQS4mI3hEO0RlcGFydG1lbnQgb2YgTWVkaWNpbmUs IEplcnNleSBDaXR5IE1lZGljYWwgQ2VudGVyLCBKZXJzZXkgQ2l0eSwgTkosIFVTQS4mI3hEO0pv aG4gT2Noc25lciBIZWFydCBhbmQgVmFzY3VsYXIgSW5zdGl0dXRlLCBPY2hzbmVyIENsaW5pY2Fs IFNjaG9vbCAtIFRoZSBVbml2ZXJzaXR5IG9mIFF1ZWVuc2xhbmQgU2Nob29sIG9mIE1lZGljaW5l LCBOZXcgT3JsZWFucywgTEEsIFVTQS4mI3hEO1RoZSBIZWFydCBJbnN0aXR1dGUsIENpbmNpbm5h dGkgQ2hpbGRyZW4mYXBvcztzIEhvc3BpdGFsIE1lZGljYWwgQ2VudGVyLCBDaW5jaW5uYXRpLCBP SCwgVVNBLiYjeEQ7U2VjdGlvbiBvZiBDbGluaWNhbCBCaW9jaGVtaXN0cnksIERlcGFydG1lbnQg b2YgTmV1cm9zY2llbmNlLCBCaW9tZWRpY2luZSBhbmQgTW92ZW1lbnQsIFVuaXZlcnNpdHkgb2Yg VmVyb25hLCBWZXJvbmEsIEl0YWx5LjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5p Y2FsIGZlYXR1cmVzLCBsYWJvcmF0b3J5IGNoYXJhY3RlcmlzdGljcywgYW5kIG91dGNvbWVzIG9m IHBhdGllbnRzIGhvc3BpdGFsaXplZCB3aXRoIGNvcm9uYXZpcnVzIGRpc2Vhc2UgMjAxOSAoQ09W SUQtMTkpOiBFYXJseSByZXBvcnQgZnJvbSB0aGUgVW5pdGVkIFN0YXRlczwvdGl0bGU+PHNlY29u ZGFyeS10aXRsZT5EaWFnbm9zaXMgKEJlcmwpPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5E aWFnbm9zaXMgKEJlcmxpbiwgR2VybWFueSk8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNh bD48ZnVsbC10aXRsZT5EaWFnbm9zaXMgKEJlcmwpPC9mdWxsLXRpdGxlPjxhYmJyLTE+RGlhZ25v c2lzIChCZXJsaW4sIEdlcm1hbnkpPC9hYmJyLTE+PC9wZXJpb2RpY2FsPjxhbHQtcGVyaW9kaWNh bD48ZnVsbC10aXRsZT5EaWFnbm9zaXMgKEJlcmwpPC9mdWxsLXRpdGxlPjxhYmJyLTE+RGlhZ25v c2lzIChCZXJsaW4sIEdlcm1hbnkpPC9hYmJyLTE+PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+OTEt OTY8L3BhZ2VzPjx2b2x1bWU+Nzwvdm9sdW1lPjxudW1iZXI+MjwvbnVtYmVyPjxlZGl0aW9uPjIw MjAvMDUvMDE8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkFkdWx0PC9rZXl3b3JkPjxrZXl3 b3JkPkFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+QWdlZCwgODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtl eXdvcmQ+KkJldGFjb3JvbmF2aXJ1czwva2V5d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZl Y3Rpb25zL2NvbXBsaWNhdGlvbnMvKnRoZXJhcHk8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9r ZXl3b3JkPjxrZXl3b3JkPkhvc3BpdGFsaXphdGlvbjwva2V5d29yZD48a2V5d29yZD5IdW1hbnM8 L2tleXdvcmQ+PGtleXdvcmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5 d29yZD48a2V5d29yZD5QYW5kZW1pY3M8L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJh bC9jb21wbGljYXRpb25zLyp0aGVyYXB5PC9rZXl3b3JkPjxrZXl3b3JkPlJldHJvc3BlY3RpdmUg U3R1ZGllczwva2V5d29yZD48a2V5d29yZD5Ub21vZ3JhcGh5LCBYLVJheSBDb21wdXRlZDwva2V5 d29yZD48a2V5d29yZD5UcmVhdG1lbnQgT3V0Y29tZTwva2V5d29yZD48a2V5d29yZD5Vbml0ZWQg U3RhdGVzPC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIwMjA8L3llYXI+PHB1Yi1k YXRlcz48ZGF0ZT5NYXkgMjY8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRlcz48aXNibj4yMTk0LTgw Mng8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIzNTI0MDE8L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91 cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xNTE1L2R4LTIwMjAtMDA0NjwvZWxlY3Ry b25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1k YXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+ PC9FbmROb3RlPgB= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5BZ2dhcndhbDwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+ PFJlY051bT41MzwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMjcpPC9EaXNwbGF5VGV4dD48cmVjb3Jk PjxyZWMtbnVtYmVyPjUzPC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBk Yi1pZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj41Mzwva2V5PjwvZm9y ZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48 Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+QWdnYXJ3YWwsIFMuPC9hdXRob3I+PGF1dGhv cj5HYXJjaWEtVGVsbGVzLCBOLjwvYXV0aG9yPjxhdXRob3I+QWdnYXJ3YWwsIEcuPC9hdXRob3I+ PGF1dGhvcj5MYXZpZSwgQy48L2F1dGhvcj48YXV0aG9yPkxpcHBpLCBHLjwvYXV0aG9yPjxhdXRo b3I+SGVucnksIEIuIE0uPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjxhdXRoLWFk ZHJlc3M+RGl2aXNpb24gb2YgQ2FyZGlvbG9neSwgRGVwYXJ0bWVudCBvZiBNZWRpY2luZSwgVW5p dHlQb2ludCBDbGluaWMsIDEyMTUgUGxlYXNhbnQgU3RyZWV0LCBTdWl0ZSA0MTQsIERlcyBNb2lu ZXMsIElBIDUwMzIzLCBVU0EuJiN4RDtEZXBhcnRtZW50IG9mIE1lZGljaW5lLCBVbml0eVBvaW50 IENsaW5pYywgRGVzIE1vaW5lcywgSUEsIFVTQS4mI3hEO0RlcGFydG1lbnQgb2YgTWVkaWNpbmUs IEplcnNleSBDaXR5IE1lZGljYWwgQ2VudGVyLCBKZXJzZXkgQ2l0eSwgTkosIFVTQS4mI3hEO0pv aG4gT2Noc25lciBIZWFydCBhbmQgVmFzY3VsYXIgSW5zdGl0dXRlLCBPY2hzbmVyIENsaW5pY2Fs IFNjaG9vbCAtIFRoZSBVbml2ZXJzaXR5IG9mIFF1ZWVuc2xhbmQgU2Nob29sIG9mIE1lZGljaW5l LCBOZXcgT3JsZWFucywgTEEsIFVTQS4mI3hEO1RoZSBIZWFydCBJbnN0aXR1dGUsIENpbmNpbm5h dGkgQ2hpbGRyZW4mYXBvcztzIEhvc3BpdGFsIE1lZGljYWwgQ2VudGVyLCBDaW5jaW5uYXRpLCBP SCwgVVNBLiYjeEQ7U2VjdGlvbiBvZiBDbGluaWNhbCBCaW9jaGVtaXN0cnksIERlcGFydG1lbnQg b2YgTmV1cm9zY2llbmNlLCBCaW9tZWRpY2luZSBhbmQgTW92ZW1lbnQsIFVuaXZlcnNpdHkgb2Yg VmVyb25hLCBWZXJvbmEsIEl0YWx5LjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5p Y2FsIGZlYXR1cmVzLCBsYWJvcmF0b3J5IGNoYXJhY3RlcmlzdGljcywgYW5kIG91dGNvbWVzIG9m IHBhdGllbnRzIGhvc3BpdGFsaXplZCB3aXRoIGNvcm9uYXZpcnVzIGRpc2Vhc2UgMjAxOSAoQ09W SUQtMTkpOiBFYXJseSByZXBvcnQgZnJvbSB0aGUgVW5pdGVkIFN0YXRlczwvdGl0bGU+PHNlY29u ZGFyeS10aXRsZT5EaWFnbm9zaXMgKEJlcmwpPC9zZWNvbmRhcnktdGl0bGU+PGFsdC10aXRsZT5E aWFnbm9zaXMgKEJlcmxpbiwgR2VybWFueSk8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNh bD48ZnVsbC10aXRsZT5EaWFnbm9zaXMgKEJlcmwpPC9mdWxsLXRpdGxlPjxhYmJyLTE+RGlhZ25v c2lzIChCZXJsaW4sIEdlcm1hbnkpPC9hYmJyLTE+PC9wZXJpb2RpY2FsPjxhbHQtcGVyaW9kaWNh bD48ZnVsbC10aXRsZT5EaWFnbm9zaXMgKEJlcmwpPC9mdWxsLXRpdGxlPjxhYmJyLTE+RGlhZ25v c2lzIChCZXJsaW4sIEdlcm1hbnkpPC9hYmJyLTE+PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+OTEt OTY8L3BhZ2VzPjx2b2x1bWU+Nzwvdm9sdW1lPjxudW1iZXI+MjwvbnVtYmVyPjxlZGl0aW9uPjIw MjAvMDUvMDE8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkFkdWx0PC9rZXl3b3JkPjxrZXl3 b3JkPkFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+QWdlZCwgODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtl eXdvcmQ+KkJldGFjb3JvbmF2aXJ1czwva2V5d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZl Y3Rpb25zL2NvbXBsaWNhdGlvbnMvKnRoZXJhcHk8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9r ZXl3b3JkPjxrZXl3b3JkPkhvc3BpdGFsaXphdGlvbjwva2V5d29yZD48a2V5d29yZD5IdW1hbnM8 L2tleXdvcmQ+PGtleXdvcmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5 d29yZD48a2V5d29yZD5QYW5kZW1pY3M8L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJh bC9jb21wbGljYXRpb25zLyp0aGVyYXB5PC9rZXl3b3JkPjxrZXl3b3JkPlJldHJvc3BlY3RpdmUg U3R1ZGllczwva2V5d29yZD48a2V5d29yZD5Ub21vZ3JhcGh5LCBYLVJheSBDb21wdXRlZDwva2V5 d29yZD48a2V5d29yZD5UcmVhdG1lbnQgT3V0Y29tZTwva2V5d29yZD48a2V5d29yZD5Vbml0ZWQg U3RhdGVzPC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIwMjA8L3llYXI+PHB1Yi1k YXRlcz48ZGF0ZT5NYXkgMjY8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRlcz48aXNibj4yMTk0LTgw Mng8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIzNTI0MDE8L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91 cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xNTE1L2R4LTIwMjAtMDA0NjwvZWxlY3Ry b25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj5ObG08L3JlbW90ZS1k YXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+ PC9FbmROb3RlPgB= ADDIN EN.CITE.DATA (27). این در حالی است که یافتههای ما با نتایج مطالعهی گان و همکاران مغایرت دارد. ایشان دریافتند که مردان بیشتر از زنان به کووید-19 مبتلا میشوند PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5HdWFuPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjc3PC9SZWNOdW0+PERpc3BsYXlUZXh0PigyOCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+Nzc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjc3PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5HdWFuLCBXLiBKLjwvYXV0aG9yPjxhdXRob3I+Tmks IFouIFkuPC9hdXRob3I+PGF1dGhvcj5IdSwgWS48L2F1dGhvcj48YXV0aG9yPkxpYW5nLCBXLiBI LjwvYXV0aG9yPjxhdXRob3I+T3UsIEMuIFEuPC9hdXRob3I+PGF1dGhvcj5IZSwgSi4gWC48L2F1 dGhvcj48YXV0aG9yPkxpdSwgTC48L2F1dGhvcj48YXV0aG9yPlNoYW4sIEguPC9hdXRob3I+PGF1 dGhvcj5MZWksIEMuIEwuPC9hdXRob3I+PGF1dGhvcj5IdWksIEQuIFMuIEMuPC9hdXRob3I+PGF1 dGhvcj5EdSwgQi48L2F1dGhvcj48YXV0aG9yPkxpLCBMLiBKLjwvYXV0aG9yPjxhdXRob3I+WmVu ZywgRy48L2F1dGhvcj48YXV0aG9yPll1ZW4sIEsuIFkuPC9hdXRob3I+PGF1dGhvcj5DaGVuLCBS LiBDLjwvYXV0aG9yPjxhdXRob3I+VGFuZywgQy4gTC48L2F1dGhvcj48YXV0aG9yPldhbmcsIFQu PC9hdXRob3I+PGF1dGhvcj5DaGVuLCBQLiBZLjwvYXV0aG9yPjxhdXRob3I+WGlhbmcsIEouPC9h dXRob3I+PGF1dGhvcj5MaSwgUy4gWS48L2F1dGhvcj48YXV0aG9yPldhbmcsIEouIEwuPC9hdXRo b3I+PGF1dGhvcj5MaWFuZywgWi4gSi48L2F1dGhvcj48YXV0aG9yPlBlbmcsIFkuIFguPC9hdXRo b3I+PGF1dGhvcj5XZWksIEwuPC9hdXRob3I+PGF1dGhvcj5MaXUsIFkuPC9hdXRob3I+PGF1dGhv cj5IdSwgWS4gSC48L2F1dGhvcj48YXV0aG9yPlBlbmcsIFAuPC9hdXRob3I+PGF1dGhvcj5XYW5n LCBKLiBNLjwvYXV0aG9yPjxhdXRob3I+TGl1LCBKLiBZLjwvYXV0aG9yPjxhdXRob3I+Q2hlbiwg Wi48L2F1dGhvcj48YXV0aG9yPkxpLCBHLjwvYXV0aG9yPjxhdXRob3I+WmhlbmcsIFouIEouPC9h dXRob3I+PGF1dGhvcj5RaXUsIFMuIFEuPC9hdXRob3I+PGF1dGhvcj5MdW8sIEouPC9hdXRob3I+ PGF1dGhvcj5ZZSwgQy4gSi48L2F1dGhvcj48YXV0aG9yPlpodSwgUy4gWS48L2F1dGhvcj48YXV0 aG9yPlpob25nLCBOLiBTLjwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48YXV0aC1h ZGRyZXNzPkZyb20gdGhlIFN0YXRlIEtleSBMYWJvcmF0b3J5IG9mIFJlc3BpcmF0b3J5IERpc2Vh c2UsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRlciBmb3IgUmVzcGlyYXRvcnkgRGlz ZWFzZSwgR3Vhbmd6aG91IEluc3RpdHV0ZSBvZiBSZXNwaXJhdG9yeSBIZWFsdGgsIEZpcnN0IEFm ZmlsaWF0ZWQgSG9zcGl0YWwgb2YgR3Vhbmd6aG91IE1lZGljYWwgVW5pdmVyc2l0eSAoVy5HLiwg Vy5MLiwgSi5ILiwgUi5DLiwgQy5ULiwgVC5XLiwgUy5MLiwgSmluLWxpbiBXYW5nLCBOLlouLCBK LkguLCBXLkwuKSwgdGhlIERlcGFydG1lbnRzIG9mIFRob3JhY2ljIE9uY29sb2d5IChXLkwuKSwg VGhvcmFjaWMgU3VyZ2VyeSBhbmQgT25jb2xvZ3kgKEouSC4pLCBhbmQgRW1lcmdlbmN5IE1lZGlj aW5lIChaLkwuKSwgRmlyc3QgQWZmaWxpYXRlZCBIb3NwaXRhbCBvZiBHdWFuZ3pob3UgTWVkaWNh bCBVbml2ZXJzaXR5LCBhbmQgR3Vhbmd6aG91IEVpZ2h0aCBQZW9wbGUmYXBvcztzIEhvc3BpdGFs LCBHdWFuZ3pob3UgTWVkaWNhbCBVbml2ZXJzaXR5IChDLkwuKSwgYW5kIHRoZSBTdGF0ZSBLZXkg TGFib3JhdG9yeSBvZiBPcmdhbiBGYWlsdXJlIFJlc2VhcmNoLCBEZXBhcnRtZW50IG9mIEJpb3N0 YXRpc3RpY3MsIEd1YW5nZG9uZyBQcm92aW5jaWFsIEtleSBMYWJvcmF0b3J5IG9mIFRyb3BpY2Fs IERpc2Vhc2UgUmVzZWFyY2gsIFNjaG9vbCBvZiBQdWJsaWMgSGVhbHRoLCBTb3V0aGVybiBNZWRp Y2FsIFVuaXZlcnNpdHkgKEMuTy4sIFAuQy4pLCBHdWFuZ3pob3UsIFd1aGFuIEppbnlpbnRhbiBI b3NwaXRhbCAoWi5OLiwgSi5YLiksIFVuaW9uIEhvc3BpdGFsLCBUb25namkgTWVkaWNhbCBDb2xs ZWdlLCBIdWF6aG9uZyBVbml2ZXJzaXR5IG9mIFNjaWVuY2UgYW5kIFRlY2hub2xvZ3kgKFl1IEh1 KSwgdGhlIENlbnRyYWwgSG9zcGl0YWwgb2YgV3VoYW4gKFkuUC4pLCBXdWhhbiBOby4gMSBIb3Nw aXRhbCwgV3VoYW4gSG9zcGl0YWwgb2YgVHJhZGl0aW9uYWwgQ2hpbmVzZSBhbmQgV2VzdGVybiBN ZWRpY2luZSAoTC5XLiksIFd1aGFuIFB1bG1vbmFyeSBIb3NwaXRhbCAoUC5QLiksIFRpYW55b3Ug SG9zcGl0YWwgQWZmaWxpYXRlZCB0byBXdWhhbiBVbml2ZXJzaXR5IG9mIFNjaWVuY2UgYW5kIFRl Y2hub2xvZ3kgKEppYW4tbWluZyBXYW5nKSwgYW5kIHRoZSBQZW9wbGUmYXBvcztzIEhvc3BpdGFs IG9mIEh1YW5ncGkgRGlzdHJpY3QgKFMuWi4pLCBXdWhhbiwgU2hlbnpoZW4gVGhpcmQgUGVvcGxl JmFwb3M7cyBIb3NwaXRhbCBhbmQgdGhlIFNlY29uZCBBZmZpbGlhdGVkIEhvc3BpdGFsIG9mIFNv dXRoZXJuIFVuaXZlcnNpdHkgb2YgU2NpZW5jZSBhbmQgVGVjaG5vbG9neSwgTmF0aW9uYWwgQ2xp bmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vhc2VzIChMLiBMaXUpLCBh bmQgdGhlIERlcGFydG1lbnQgb2YgQ2xpbmljYWwgTWljcm9iaW9sb2d5IGFuZCBJbmZlY3Rpb24g Q29udHJvbCwgVW5pdmVyc2l0eSBvZiBIb25nIEtvbmctU2hlbnpoZW4gSG9zcGl0YWwgKEsuLVku WS4pLCBTaGVuemhlbiwgdGhlIEZpZnRoIEFmZmlsaWF0ZWQgSG9zcGl0YWwgb2YgU3VuIFlhdC1z ZW4gVW5pdmVyc2l0eSwgWmh1aGFpIChILlMuKSwgdGhlIERlcGFydG1lbnQgb2YgTWVkaWNpbmUg YW5kIFRoZXJhcGV1dGljcywgQ2hpbmVzZSBVbml2ZXJzaXR5IG9mIEhvbmcgS29uZywgU2hhdGlu IChELlMuQy5ILiksIGFuZCB0aGUgRGVwYXJ0bWVudCBvZiBNaWNyb2Jpb2xvZ3kgYW5kIHRoZSBD YXJvbCBZdSBDZW50ZXIgZm9yIEluZmVjdGlvbiwgTGkgS2EgU2hpbmcgRmFjdWx0eSBvZiBNZWRp Y2luZSwgVW5pdmVyc2l0eSBvZiBIb25nIEtvbmcsIFBvayBGdSBMYW0gKEsuLVkuWS4pLCBIb25n IEtvbmcsIE1lZGljYWwgSUNVLCBQZWtpbmcgVW5pb24gTWVkaWNhbCBDb2xsZWdlIEhvc3BpdGFs LCBQZWtpbmcgVW5pb24gTWVkaWNhbCBDb2xsZWdlIGFuZCBDaGluZXNlIEFjYWRlbXkgb2YgTWVk aWNhbCBTY2llbmNlcyAoQi5ELiksIGFuZCB0aGUgQ2hpbmVzZSBDZW50ZXIgZm9yIERpc2Vhc2Ug Q29udHJvbCBhbmQgUHJldmVudGlvbiAoRy5aLiksIEJlaWppbmcsIHRoZSBTdGF0ZSBLZXkgTGFi b3JhdG9yeSBmb3IgRGlhZ25vc2lzIGFuZCBUcmVhdG1lbnQgb2YgSW5mZWN0aW91cyBEaXNlYXNl cywgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vh c2VzLCBGaXJzdCBBZmZpbGlhdGVkIEhvc3BpdGFsLCBDb2xsZWdlIG9mIE1lZGljaW5lLCBaaGVq aWFuZyBVbml2ZXJzaXR5LCBIYW5nemhvdSAoTC4gTGkpLCBDaGVuZ2R1IFB1YmxpYyBIZWFsdGgg Q2xpbmljYWwgTWVkaWNhbCBDZW50ZXIsIENoZW5nZHUgKFkuTC4pLCBIdWFuZ3NoaSBDZW50cmFs IEhvc3BpdGFsIG9mIEVkb25nIEhlYWx0aGNhcmUgR3JvdXAsIEFmZmlsaWF0ZWQgSG9zcGl0YWwg b2YgSHViZWkgUG9seXRlY2huaWMgVW5pdmVyc2l0eSwgSHVhbmdzaGkgKFlhLWh1YSBIdSksIHRo ZSBGaXJzdCBIb3NwaXRhbCBvZiBDaGFuZ3NoYSwgQ2hhbmdzaGEgKEouIExpdSksIHRoZSBUaGly ZCBQZW9wbGUmYXBvcztzIEhvc3BpdGFsIG9mIEhhaW5hbiBQcm92aW5jZSwgU2FueWEgKFouQy4p LCBIdWFuZ2dhbmcgQ2VudHJhbCBIb3NwaXRhbCwgSHVhbmdnYW5nIChHLkwuKSwgV2VubGluZyBG aXJzdCBQZW9wbGUmYXBvcztzIEhvc3BpdGFsLCBXZW5saW5nIChaLlouKSwgdGhlIFRoaXJkIFBl b3BsZSZhcG9zO3MgSG9zcGl0YWwgb2YgWWljaGFuZywgWWljaGFuZyAoUy5RLiksIEFmZmlsaWF0 ZWQgVGFpaGUgSG9zcGl0YWwgb2YgSHViZWkgVW5pdmVyc2l0eSBvZiBNZWRpY2luZSwgU2hpeWFu IChKLiBMdW8pLCBhbmQgWGlhbnRhbyBGaXJzdCBQZW9wbGUmYXBvcztzIEhvc3BpdGFsLCBYaWFu dGFvIChDLlkuKSAtIGFsbCBpbiBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRsZT5D bGluaWNhbCBDaGFyYWN0ZXJpc3RpY3Mgb2YgQ29yb25hdmlydXMgRGlzZWFzZSAyMDE5IGluIENo aW5hPC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPk4gRW5nbCBKIE1lZDwvc2Vjb25kYXJ5LXRpdGxl PjxhbHQtdGl0bGU+VGhlIE5ldyBFbmdsYW5kIGpvdXJuYWwgb2YgbWVkaWNpbmU8L2FsdC10aXRs ZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5OIEVuZ2wgSiBNZWQ8L2Z1bGwtdGl0 bGU+PGFiYnItMT5UaGUgTmV3IEVuZ2xhbmQgam91cm5hbCBvZiBtZWRpY2luZTwvYWJici0xPjwv cGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TiBFbmdsIEogTWVkPC9mdWxs LXRpdGxlPjxhYmJyLTE+VGhlIE5ldyBFbmdsYW5kIGpvdXJuYWwgb2YgbWVkaWNpbmU8L2FiYnIt MT48L2FsdC1wZXJpb2RpY2FsPjxwYWdlcz4xNzA4LTE3MjA8L3BhZ2VzPjx2b2x1bWU+MzgyPC92 b2x1bWU+PG51bWJlcj4xODwvbnVtYmVyPjxlZGl0aW9uPjIwMjAvMDIvMjk8L2VkaXRpb24+PGtl eXdvcmRzPjxrZXl3b3JkPkFkb2xlc2NlbnQ8L2tleXdvcmQ+PGtleXdvcmQ+QWR1bHQ8L2tleXdv cmQ+PGtleXdvcmQ+QWdlZDwva2V5d29yZD48a2V5d29yZD4qQmV0YWNvcm9uYXZpcnVzPC9rZXl3 b3JkPjxrZXl3b3JkPkNoaWxkPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwv a2V5d29yZD48a2V5d29yZD4qQ29yb25hdmlydXMgSW5mZWN0aW9ucy9jb21wbGljYXRpb25zL2Rp YWdub3Npcy9lcGlkZW1pb2xvZ3kvdGhlcmFweTwva2V5d29yZD48a2V5d29yZD4qRGlzZWFzZSBP dXRicmVha3M8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkZldmVy L2V0aW9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5NYWxl PC9rZXl3b3JkPjxrZXl3b3JkPk1pZGRsZSBBZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPipQYW5kZW1p Y3M8L2tleXdvcmQ+PGtleXdvcmQ+UGF0aWVudCBBY3VpdHk8L2tleXdvcmQ+PGtleXdvcmQ+KlBu ZXVtb25pYSwgVmlyYWwvY29tcGxpY2F0aW9ucy9kaWFnbm9zaXMvZXBpZGVtaW9sb2d5L3RoZXJh cHk8L2tleXdvcmQ+PGtleXdvcmQ+WW91bmcgQWR1bHQ8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0 ZXM+PHllYXI+MjAyMDwveWVhcj48cHViLWRhdGVzPjxkYXRlPkFwciAzMDwvZGF0ZT48L3B1Yi1k YXRlcz48L2RhdGVzPjxpc2JuPjAwMjgtNDc5MyAoUHJpbnQpJiN4RDswMDI4LTQ3OTM8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMDkwMTM8L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0 b20yPlBtYzcwOTI4MTk8L2N1c3RvbTI+PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwNTYv TkVKTW9hMjAwMjAzMjwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1w cm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5n dWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5HdWFuPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVj TnVtPjc3PC9SZWNOdW0+PERpc3BsYXlUZXh0PigyOCk8L0Rpc3BsYXlUZXh0PjxyZWNvcmQ+PHJl Yy1udW1iZXI+Nzc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlk PSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjc3PC9rZXk+PC9mb3JlaWdu LWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250 cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5HdWFuLCBXLiBKLjwvYXV0aG9yPjxhdXRob3I+Tmks IFouIFkuPC9hdXRob3I+PGF1dGhvcj5IdSwgWS48L2F1dGhvcj48YXV0aG9yPkxpYW5nLCBXLiBI LjwvYXV0aG9yPjxhdXRob3I+T3UsIEMuIFEuPC9hdXRob3I+PGF1dGhvcj5IZSwgSi4gWC48L2F1 dGhvcj48YXV0aG9yPkxpdSwgTC48L2F1dGhvcj48YXV0aG9yPlNoYW4sIEguPC9hdXRob3I+PGF1 dGhvcj5MZWksIEMuIEwuPC9hdXRob3I+PGF1dGhvcj5IdWksIEQuIFMuIEMuPC9hdXRob3I+PGF1 dGhvcj5EdSwgQi48L2F1dGhvcj48YXV0aG9yPkxpLCBMLiBKLjwvYXV0aG9yPjxhdXRob3I+WmVu ZywgRy48L2F1dGhvcj48YXV0aG9yPll1ZW4sIEsuIFkuPC9hdXRob3I+PGF1dGhvcj5DaGVuLCBS LiBDLjwvYXV0aG9yPjxhdXRob3I+VGFuZywgQy4gTC48L2F1dGhvcj48YXV0aG9yPldhbmcsIFQu PC9hdXRob3I+PGF1dGhvcj5DaGVuLCBQLiBZLjwvYXV0aG9yPjxhdXRob3I+WGlhbmcsIEouPC9h dXRob3I+PGF1dGhvcj5MaSwgUy4gWS48L2F1dGhvcj48YXV0aG9yPldhbmcsIEouIEwuPC9hdXRo b3I+PGF1dGhvcj5MaWFuZywgWi4gSi48L2F1dGhvcj48YXV0aG9yPlBlbmcsIFkuIFguPC9hdXRo b3I+PGF1dGhvcj5XZWksIEwuPC9hdXRob3I+PGF1dGhvcj5MaXUsIFkuPC9hdXRob3I+PGF1dGhv cj5IdSwgWS4gSC48L2F1dGhvcj48YXV0aG9yPlBlbmcsIFAuPC9hdXRob3I+PGF1dGhvcj5XYW5n LCBKLiBNLjwvYXV0aG9yPjxhdXRob3I+TGl1LCBKLiBZLjwvYXV0aG9yPjxhdXRob3I+Q2hlbiwg Wi48L2F1dGhvcj48YXV0aG9yPkxpLCBHLjwvYXV0aG9yPjxhdXRob3I+WmhlbmcsIFouIEouPC9h dXRob3I+PGF1dGhvcj5RaXUsIFMuIFEuPC9hdXRob3I+PGF1dGhvcj5MdW8sIEouPC9hdXRob3I+ PGF1dGhvcj5ZZSwgQy4gSi48L2F1dGhvcj48YXV0aG9yPlpodSwgUy4gWS48L2F1dGhvcj48YXV0 aG9yPlpob25nLCBOLiBTLjwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48YXV0aC1h ZGRyZXNzPkZyb20gdGhlIFN0YXRlIEtleSBMYWJvcmF0b3J5IG9mIFJlc3BpcmF0b3J5IERpc2Vh c2UsIE5hdGlvbmFsIENsaW5pY2FsIFJlc2VhcmNoIENlbnRlciBmb3IgUmVzcGlyYXRvcnkgRGlz ZWFzZSwgR3Vhbmd6aG91IEluc3RpdHV0ZSBvZiBSZXNwaXJhdG9yeSBIZWFsdGgsIEZpcnN0IEFm ZmlsaWF0ZWQgSG9zcGl0YWwgb2YgR3Vhbmd6aG91IE1lZGljYWwgVW5pdmVyc2l0eSAoVy5HLiwg Vy5MLiwgSi5ILiwgUi5DLiwgQy5ULiwgVC5XLiwgUy5MLiwgSmluLWxpbiBXYW5nLCBOLlouLCBK LkguLCBXLkwuKSwgdGhlIERlcGFydG1lbnRzIG9mIFRob3JhY2ljIE9uY29sb2d5IChXLkwuKSwg VGhvcmFjaWMgU3VyZ2VyeSBhbmQgT25jb2xvZ3kgKEouSC4pLCBhbmQgRW1lcmdlbmN5IE1lZGlj aW5lIChaLkwuKSwgRmlyc3QgQWZmaWxpYXRlZCBIb3NwaXRhbCBvZiBHdWFuZ3pob3UgTWVkaWNh bCBVbml2ZXJzaXR5LCBhbmQgR3Vhbmd6aG91IEVpZ2h0aCBQZW9wbGUmYXBvcztzIEhvc3BpdGFs LCBHdWFuZ3pob3UgTWVkaWNhbCBVbml2ZXJzaXR5IChDLkwuKSwgYW5kIHRoZSBTdGF0ZSBLZXkg TGFib3JhdG9yeSBvZiBPcmdhbiBGYWlsdXJlIFJlc2VhcmNoLCBEZXBhcnRtZW50IG9mIEJpb3N0 YXRpc3RpY3MsIEd1YW5nZG9uZyBQcm92aW5jaWFsIEtleSBMYWJvcmF0b3J5IG9mIFRyb3BpY2Fs IERpc2Vhc2UgUmVzZWFyY2gsIFNjaG9vbCBvZiBQdWJsaWMgSGVhbHRoLCBTb3V0aGVybiBNZWRp Y2FsIFVuaXZlcnNpdHkgKEMuTy4sIFAuQy4pLCBHdWFuZ3pob3UsIFd1aGFuIEppbnlpbnRhbiBI b3NwaXRhbCAoWi5OLiwgSi5YLiksIFVuaW9uIEhvc3BpdGFsLCBUb25namkgTWVkaWNhbCBDb2xs ZWdlLCBIdWF6aG9uZyBVbml2ZXJzaXR5IG9mIFNjaWVuY2UgYW5kIFRlY2hub2xvZ3kgKFl1IEh1 KSwgdGhlIENlbnRyYWwgSG9zcGl0YWwgb2YgV3VoYW4gKFkuUC4pLCBXdWhhbiBOby4gMSBIb3Nw aXRhbCwgV3VoYW4gSG9zcGl0YWwgb2YgVHJhZGl0aW9uYWwgQ2hpbmVzZSBhbmQgV2VzdGVybiBN ZWRpY2luZSAoTC5XLiksIFd1aGFuIFB1bG1vbmFyeSBIb3NwaXRhbCAoUC5QLiksIFRpYW55b3Ug SG9zcGl0YWwgQWZmaWxpYXRlZCB0byBXdWhhbiBVbml2ZXJzaXR5IG9mIFNjaWVuY2UgYW5kIFRl Y2hub2xvZ3kgKEppYW4tbWluZyBXYW5nKSwgYW5kIHRoZSBQZW9wbGUmYXBvcztzIEhvc3BpdGFs IG9mIEh1YW5ncGkgRGlzdHJpY3QgKFMuWi4pLCBXdWhhbiwgU2hlbnpoZW4gVGhpcmQgUGVvcGxl JmFwb3M7cyBIb3NwaXRhbCBhbmQgdGhlIFNlY29uZCBBZmZpbGlhdGVkIEhvc3BpdGFsIG9mIFNv dXRoZXJuIFVuaXZlcnNpdHkgb2YgU2NpZW5jZSBhbmQgVGVjaG5vbG9neSwgTmF0aW9uYWwgQ2xp bmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vhc2VzIChMLiBMaXUpLCBh bmQgdGhlIERlcGFydG1lbnQgb2YgQ2xpbmljYWwgTWljcm9iaW9sb2d5IGFuZCBJbmZlY3Rpb24g Q29udHJvbCwgVW5pdmVyc2l0eSBvZiBIb25nIEtvbmctU2hlbnpoZW4gSG9zcGl0YWwgKEsuLVku WS4pLCBTaGVuemhlbiwgdGhlIEZpZnRoIEFmZmlsaWF0ZWQgSG9zcGl0YWwgb2YgU3VuIFlhdC1z ZW4gVW5pdmVyc2l0eSwgWmh1aGFpIChILlMuKSwgdGhlIERlcGFydG1lbnQgb2YgTWVkaWNpbmUg YW5kIFRoZXJhcGV1dGljcywgQ2hpbmVzZSBVbml2ZXJzaXR5IG9mIEhvbmcgS29uZywgU2hhdGlu IChELlMuQy5ILiksIGFuZCB0aGUgRGVwYXJ0bWVudCBvZiBNaWNyb2Jpb2xvZ3kgYW5kIHRoZSBD YXJvbCBZdSBDZW50ZXIgZm9yIEluZmVjdGlvbiwgTGkgS2EgU2hpbmcgRmFjdWx0eSBvZiBNZWRp Y2luZSwgVW5pdmVyc2l0eSBvZiBIb25nIEtvbmcsIFBvayBGdSBMYW0gKEsuLVkuWS4pLCBIb25n IEtvbmcsIE1lZGljYWwgSUNVLCBQZWtpbmcgVW5pb24gTWVkaWNhbCBDb2xsZWdlIEhvc3BpdGFs LCBQZWtpbmcgVW5pb24gTWVkaWNhbCBDb2xsZWdlIGFuZCBDaGluZXNlIEFjYWRlbXkgb2YgTWVk aWNhbCBTY2llbmNlcyAoQi5ELiksIGFuZCB0aGUgQ2hpbmVzZSBDZW50ZXIgZm9yIERpc2Vhc2Ug Q29udHJvbCBhbmQgUHJldmVudGlvbiAoRy5aLiksIEJlaWppbmcsIHRoZSBTdGF0ZSBLZXkgTGFi b3JhdG9yeSBmb3IgRGlhZ25vc2lzIGFuZCBUcmVhdG1lbnQgb2YgSW5mZWN0aW91cyBEaXNlYXNl cywgTmF0aW9uYWwgQ2xpbmljYWwgUmVzZWFyY2ggQ2VudGVyIGZvciBJbmZlY3Rpb3VzIERpc2Vh c2VzLCBGaXJzdCBBZmZpbGlhdGVkIEhvc3BpdGFsLCBDb2xsZWdlIG9mIE1lZGljaW5lLCBaaGVq aWFuZyBVbml2ZXJzaXR5LCBIYW5nemhvdSAoTC4gTGkpLCBDaGVuZ2R1IFB1YmxpYyBIZWFsdGgg Q2xpbmljYWwgTWVkaWNhbCBDZW50ZXIsIENoZW5nZHUgKFkuTC4pLCBIdWFuZ3NoaSBDZW50cmFs IEhvc3BpdGFsIG9mIEVkb25nIEhlYWx0aGNhcmUgR3JvdXAsIEFmZmlsaWF0ZWQgSG9zcGl0YWwg b2YgSHViZWkgUG9seXRlY2huaWMgVW5pdmVyc2l0eSwgSHVhbmdzaGkgKFlhLWh1YSBIdSksIHRo ZSBGaXJzdCBIb3NwaXRhbCBvZiBDaGFuZ3NoYSwgQ2hhbmdzaGEgKEouIExpdSksIHRoZSBUaGly ZCBQZW9wbGUmYXBvcztzIEhvc3BpdGFsIG9mIEhhaW5hbiBQcm92aW5jZSwgU2FueWEgKFouQy4p LCBIdWFuZ2dhbmcgQ2VudHJhbCBIb3NwaXRhbCwgSHVhbmdnYW5nIChHLkwuKSwgV2VubGluZyBG aXJzdCBQZW9wbGUmYXBvcztzIEhvc3BpdGFsLCBXZW5saW5nIChaLlouKSwgdGhlIFRoaXJkIFBl b3BsZSZhcG9zO3MgSG9zcGl0YWwgb2YgWWljaGFuZywgWWljaGFuZyAoUy5RLiksIEFmZmlsaWF0 ZWQgVGFpaGUgSG9zcGl0YWwgb2YgSHViZWkgVW5pdmVyc2l0eSBvZiBNZWRpY2luZSwgU2hpeWFu IChKLiBMdW8pLCBhbmQgWGlhbnRhbyBGaXJzdCBQZW9wbGUmYXBvcztzIEhvc3BpdGFsLCBYaWFu dGFvIChDLlkuKSAtIGFsbCBpbiBDaGluYS48L2F1dGgtYWRkcmVzcz48dGl0bGVzPjx0aXRsZT5D bGluaWNhbCBDaGFyYWN0ZXJpc3RpY3Mgb2YgQ29yb25hdmlydXMgRGlzZWFzZSAyMDE5IGluIENo aW5hPC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPk4gRW5nbCBKIE1lZDwvc2Vjb25kYXJ5LXRpdGxl PjxhbHQtdGl0bGU+VGhlIE5ldyBFbmdsYW5kIGpvdXJuYWwgb2YgbWVkaWNpbmU8L2FsdC10aXRs ZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5OIEVuZ2wgSiBNZWQ8L2Z1bGwtdGl0 bGU+PGFiYnItMT5UaGUgTmV3IEVuZ2xhbmQgam91cm5hbCBvZiBtZWRpY2luZTwvYWJici0xPjwv cGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+TiBFbmdsIEogTWVkPC9mdWxs LXRpdGxlPjxhYmJyLTE+VGhlIE5ldyBFbmdsYW5kIGpvdXJuYWwgb2YgbWVkaWNpbmU8L2FiYnIt MT48L2FsdC1wZXJpb2RpY2FsPjxwYWdlcz4xNzA4LTE3MjA8L3BhZ2VzPjx2b2x1bWU+MzgyPC92 b2x1bWU+PG51bWJlcj4xODwvbnVtYmVyPjxlZGl0aW9uPjIwMjAvMDIvMjk8L2VkaXRpb24+PGtl eXdvcmRzPjxrZXl3b3JkPkFkb2xlc2NlbnQ8L2tleXdvcmQ+PGtleXdvcmQ+QWR1bHQ8L2tleXdv cmQ+PGtleXdvcmQ+QWdlZDwva2V5d29yZD48a2V5d29yZD4qQmV0YWNvcm9uYXZpcnVzPC9rZXl3 b3JkPjxrZXl3b3JkPkNoaWxkPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwv a2V5d29yZD48a2V5d29yZD4qQ29yb25hdmlydXMgSW5mZWN0aW9ucy9jb21wbGljYXRpb25zL2Rp YWdub3Npcy9lcGlkZW1pb2xvZ3kvdGhlcmFweTwva2V5d29yZD48a2V5d29yZD4qRGlzZWFzZSBP dXRicmVha3M8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPkZldmVy L2V0aW9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5NYWxl PC9rZXl3b3JkPjxrZXl3b3JkPk1pZGRsZSBBZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPipQYW5kZW1p Y3M8L2tleXdvcmQ+PGtleXdvcmQ+UGF0aWVudCBBY3VpdHk8L2tleXdvcmQ+PGtleXdvcmQ+KlBu ZXVtb25pYSwgVmlyYWwvY29tcGxpY2F0aW9ucy9kaWFnbm9zaXMvZXBpZGVtaW9sb2d5L3RoZXJh cHk8L2tleXdvcmQ+PGtleXdvcmQ+WW91bmcgQWR1bHQ8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0 ZXM+PHllYXI+MjAyMDwveWVhcj48cHViLWRhdGVzPjxkYXRlPkFwciAzMDwvZGF0ZT48L3B1Yi1k YXRlcz48L2RhdGVzPjxpc2JuPjAwMjgtNDc5MyAoUHJpbnQpJiN4RDswMDI4LTQ3OTM8L2lzYm4+ PGFjY2Vzc2lvbi1udW0+MzIxMDkwMTM8L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0 b20yPlBtYzcwOTI4MTk8L2N1c3RvbTI+PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwNTYv TkVKTW9hMjAwMjAzMjwvZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+PHJlbW90ZS1kYXRhYmFzZS1w cm92aWRlcj5ObG08L3JlbW90ZS1kYXRhYmFzZS1wcm92aWRlcj48bGFuZ3VhZ2U+ZW5nPC9sYW5n dWFnZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE.DATA (28). در مورد سیگارکشیدن، اگرچه چندین مطالعه به پیشرفت به سمت فرم شدید بیماری و بروز نتایج نامطلوب کووید-19 در بیماران اشاره کردهاند PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5DYXR0YXJ1enphPC9BdXRob3I+PFllYXI+MjAyMDwvWWVh cj48UmVjTnVtPjc4PC9SZWNOdW0+PERpc3BsYXlUZXh0PigyOSwgMzApPC9EaXNwbGF5VGV4dD48 cmVjb3JkPjxyZWMtbnVtYmVyPjc4PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9 IkVOIiBkYi1pZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj43ODwva2V5 PjwvZm9yZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYt dHlwZT48Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+Q2F0dGFydXp6YSwgTWFyaWEgU29m aWE8L2F1dGhvcj48YXV0aG9yPlphZ8OgLCBWaW5jZW56bzwvYXV0aG9yPjxhdXRob3I+R2FsbHVz LCBTaWx2YW5vPC9hdXRob3I+PGF1dGhvcj5EJmFwb3M7QXJnZW5pbywgUGFvbG88L2F1dGhvcj48 YXV0aG9yPkdvcmluaSwgR2l1c2VwcGU8L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+ PHRpdGxlcz48dGl0bGU+VG9iYWNjbyBzbW9raW5nIGFuZCBDT1ZJRC0xOSBwYW5kZW1pYzogb2xk IGFuZCBuZXcgaXNzdWVzLiBBIHN1bW1hcnkgb2YgdGhlIGV2aWRlbmNlIGZyb20gdGhlIHNjaWVu dGlmaWMgbGl0ZXJhdHVyZTwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5BY3RhIEJpbyBNZWRpY2Eg QXRlbmVpIFBhcm1lbnNpczwvc2Vjb25kYXJ5LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkFjdGEgQmlvIE1lZGljYSBBdGVuZWkgUGFybWVuc2lzPC9mdWxsLXRpdGxlPjwv cGVyaW9kaWNhbD48cGFnZXM+MTA2LTExMjwvcGFnZXM+PHZvbHVtZT45MTwvdm9sdW1lPjxudW1i ZXI+MjwvbnVtYmVyPjxzZWN0aW9uPk9SSUdJTkFMIElOVkVTVElHQVRJT05TL0NPTU1FTlRBUklF UyAtIFNQRUNJQUwgQ09WSUQxOTwvc2VjdGlvbj48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48cHVi LWRhdGVzPjxkYXRlPjA1LzExPC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PHVybHM+PHJlbGF0 ZWQtdXJscz48dXJsPmh0dHBzOi8vd3d3Lm1hdHRpb2xpMTg4NWpvdXJuYWxzLmNvbS9pbmRleC5w aHAvYWN0YWJpb21lZGljYS9hcnRpY2xlL3ZpZXcvOTY5ODwvdXJsPjwvcmVsYXRlZC11cmxzPjwv dXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMjM3NTAvYWJtLnY5MWkyLjk2OTg8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxhY2Nlc3MtZGF0ZT4yMDIwLzExLzIzPC9hY2Nlc3MtZGF0 ZT48L3JlY29yZD48L0NpdGU+PENpdGU+PEF1dGhvcj5WYXJkYXZhczwvQXV0aG9yPjxZZWFyPjIw MjA8L1llYXI+PFJlY051bT43OTwvUmVjTnVtPjxyZWNvcmQ+PHJlYy1udW1iZXI+Nzk8L3JlYy1u dW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlkPSI5cjIyMHhzOTZwZTJ2cGVm dDIxcDB0dDUwNXZwdjIydHhkZWQiPjc5PC9rZXk+PC9mb3JlaWduLWtleXM+PHJlZi10eXBlIG5h bWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250cmlidXRvcnM+PGF1dGhvcnM+ PGF1dGhvcj5WYXJkYXZhcywgQ29uc3RhbnRpbmUgSS48L2F1dGhvcj48YXV0aG9yPk5pa2l0YXJh LCBLYXRlcmluYTwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48dGl0bGVzPjx0aXRs ZT5DT1ZJRC0xOSBhbmQgc21va2luZzogQSBzeXN0ZW1hdGljIHJldmlldyBvZiB0aGUgZXZpZGVu Y2U8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+VG9iYWNjbyBpbmR1Y2VkIGRpc2Vhc2VzPC9zZWNv bmRhcnktdGl0bGU+PGFsdC10aXRsZT5Ub2IgSW5kdWMgRGlzPC9hbHQtdGl0bGU+PC90aXRsZXM+ PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+VG9iYWNjbyBpbmR1Y2VkIGRpc2Vhc2VzPC9mdWxsLXRp dGxlPjxhYmJyLTE+VG9iIEluZHVjIERpczwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlv ZGljYWw+PGZ1bGwtdGl0bGU+VG9iYWNjbyBpbmR1Y2VkIGRpc2Vhc2VzPC9mdWxsLXRpdGxlPjxh YmJyLTE+VG9iIEluZHVjIERpczwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+PHBhZ2VzPjIwLTIw PC9wYWdlcz48dm9sdW1lPjE4PC92b2x1bWU+PGtleXdvcmRzPjxrZXl3b3JkPkNPVklELTE5PC9r ZXl3b3JkPjxrZXl3b3JkPmNvcm9uYXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPnNtb2tpbmc8L2tl eXdvcmQ+PGtleXdvcmQ+dG9iYWNjbzwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4y MDIwPC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FdXJvcGVhbiBQdWJsaXNoaW5nIG9uIGJlaGFs ZiBvZiB0aGUgSW50ZXJuYXRpb25hbCBTb2NpZXR5IGZvciB0aGUgUHJldmVudGlvbiBvZiBUb2Jh Y2NvIEluZHVjZWQgRGlzZWFzZXMgKElTUFRJRCk8L3B1Ymxpc2hlcj48aXNibj4xNjE3LTk2MjUm I3hEOzIwNzAtNzI2NjwvaXNibj48YWNjZXNzaW9uLW51bT4zMjIwNjA1MjwvYWNjZXNzaW9uLW51 bT48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9wdWJtZWQubmNiaS5ubG0ubmloLmdv di8zMjIwNjA1MjwvdXJsPjx1cmw+aHR0cHM6Ly93d3cubmNiaS5ubG0ubmloLmdvdi9wbWMvYXJ0 aWNsZXMvUE1DNzA4MzI0MC88L3VybD48L3JlbGF0ZWQtdXJscz48L3VybHM+PGVsZWN0cm9uaWMt cmVzb3VyY2UtbnVtPjEwLjE4MzMyL3RpZC8xMTkzMjQ8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVt PjxyZW1vdGUtZGF0YWJhc2UtbmFtZT5QdWJNZWQ8L3JlbW90ZS1kYXRhYmFzZS1uYW1lPjxsYW5n dWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5DYXR0YXJ1enphPC9BdXRob3I+PFllYXI+MjAyMDwvWWVh cj48UmVjTnVtPjc4PC9SZWNOdW0+PERpc3BsYXlUZXh0PigyOSwgMzApPC9EaXNwbGF5VGV4dD48 cmVjb3JkPjxyZWMtbnVtYmVyPjc4PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9 IkVOIiBkYi1pZD0iOXIyMjB4czk2cGUydnBlZnQyMXAwdHQ1MDV2cHYyMnR4ZGVkIj43ODwva2V5 PjwvZm9yZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYt dHlwZT48Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+Q2F0dGFydXp6YSwgTWFyaWEgU29m aWE8L2F1dGhvcj48YXV0aG9yPlphZ8OgLCBWaW5jZW56bzwvYXV0aG9yPjxhdXRob3I+R2FsbHVz LCBTaWx2YW5vPC9hdXRob3I+PGF1dGhvcj5EJmFwb3M7QXJnZW5pbywgUGFvbG88L2F1dGhvcj48 YXV0aG9yPkdvcmluaSwgR2l1c2VwcGU8L2F1dGhvcj48L2F1dGhvcnM+PC9jb250cmlidXRvcnM+ PHRpdGxlcz48dGl0bGU+VG9iYWNjbyBzbW9raW5nIGFuZCBDT1ZJRC0xOSBwYW5kZW1pYzogb2xk IGFuZCBuZXcgaXNzdWVzLiBBIHN1bW1hcnkgb2YgdGhlIGV2aWRlbmNlIGZyb20gdGhlIHNjaWVu dGlmaWMgbGl0ZXJhdHVyZTwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5BY3RhIEJpbyBNZWRpY2Eg QXRlbmVpIFBhcm1lbnNpczwvc2Vjb25kYXJ5LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxm dWxsLXRpdGxlPkFjdGEgQmlvIE1lZGljYSBBdGVuZWkgUGFybWVuc2lzPC9mdWxsLXRpdGxlPjwv cGVyaW9kaWNhbD48cGFnZXM+MTA2LTExMjwvcGFnZXM+PHZvbHVtZT45MTwvdm9sdW1lPjxudW1i ZXI+MjwvbnVtYmVyPjxzZWN0aW9uPk9SSUdJTkFMIElOVkVTVElHQVRJT05TL0NPTU1FTlRBUklF UyAtIFNQRUNJQUwgQ09WSUQxOTwvc2VjdGlvbj48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48cHVi LWRhdGVzPjxkYXRlPjA1LzExPC9kYXRlPjwvcHViLWRhdGVzPjwvZGF0ZXM+PHVybHM+PHJlbGF0 ZWQtdXJscz48dXJsPmh0dHBzOi8vd3d3Lm1hdHRpb2xpMTg4NWpvdXJuYWxzLmNvbS9pbmRleC5w aHAvYWN0YWJpb21lZGljYS9hcnRpY2xlL3ZpZXcvOTY5ODwvdXJsPjwvcmVsYXRlZC11cmxzPjwv dXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMjM3NTAvYWJtLnY5MWkyLjk2OTg8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxhY2Nlc3MtZGF0ZT4yMDIwLzExLzIzPC9hY2Nlc3MtZGF0 ZT48L3JlY29yZD48L0NpdGU+PENpdGU+PEF1dGhvcj5WYXJkYXZhczwvQXV0aG9yPjxZZWFyPjIw MjA8L1llYXI+PFJlY051bT43OTwvUmVjTnVtPjxyZWNvcmQ+PHJlYy1udW1iZXI+Nzk8L3JlYy1u dW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRiLWlkPSI5cjIyMHhzOTZwZTJ2cGVm dDIxcDB0dDUwNXZwdjIydHhkZWQiPjc5PC9rZXk+PC9mb3JlaWduLWtleXM+PHJlZi10eXBlIG5h bWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10eXBlPjxjb250cmlidXRvcnM+PGF1dGhvcnM+ PGF1dGhvcj5WYXJkYXZhcywgQ29uc3RhbnRpbmUgSS48L2F1dGhvcj48YXV0aG9yPk5pa2l0YXJh LCBLYXRlcmluYTwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48dGl0bGVzPjx0aXRs ZT5DT1ZJRC0xOSBhbmQgc21va2luZzogQSBzeXN0ZW1hdGljIHJldmlldyBvZiB0aGUgZXZpZGVu Y2U8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+VG9iYWNjbyBpbmR1Y2VkIGRpc2Vhc2VzPC9zZWNv bmRhcnktdGl0bGU+PGFsdC10aXRsZT5Ub2IgSW5kdWMgRGlzPC9hbHQtdGl0bGU+PC90aXRsZXM+ PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+VG9iYWNjbyBpbmR1Y2VkIGRpc2Vhc2VzPC9mdWxsLXRp dGxlPjxhYmJyLTE+VG9iIEluZHVjIERpczwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlv ZGljYWw+PGZ1bGwtdGl0bGU+VG9iYWNjbyBpbmR1Y2VkIGRpc2Vhc2VzPC9mdWxsLXRpdGxlPjxh YmJyLTE+VG9iIEluZHVjIERpczwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+PHBhZ2VzPjIwLTIw PC9wYWdlcz48dm9sdW1lPjE4PC92b2x1bWU+PGtleXdvcmRzPjxrZXl3b3JkPkNPVklELTE5PC9r ZXl3b3JkPjxrZXl3b3JkPmNvcm9uYXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPnNtb2tpbmc8L2tl eXdvcmQ+PGtleXdvcmQ+dG9iYWNjbzwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4y MDIwPC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FdXJvcGVhbiBQdWJsaXNoaW5nIG9uIGJlaGFs ZiBvZiB0aGUgSW50ZXJuYXRpb25hbCBTb2NpZXR5IGZvciB0aGUgUHJldmVudGlvbiBvZiBUb2Jh Y2NvIEluZHVjZWQgRGlzZWFzZXMgKElTUFRJRCk8L3B1Ymxpc2hlcj48aXNibj4xNjE3LTk2MjUm I3hEOzIwNzAtNzI2NjwvaXNibj48YWNjZXNzaW9uLW51bT4zMjIwNjA1MjwvYWNjZXNzaW9uLW51 bT48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9wdWJtZWQubmNiaS5ubG0ubmloLmdv di8zMjIwNjA1MjwvdXJsPjx1cmw+aHR0cHM6Ly93d3cubmNiaS5ubG0ubmloLmdvdi9wbWMvYXJ0 aWNsZXMvUE1DNzA4MzI0MC88L3VybD48L3JlbGF0ZWQtdXJscz48L3VybHM+PGVsZWN0cm9uaWMt cmVzb3VyY2UtbnVtPjEwLjE4MzMyL3RpZC8xMTkzMjQ8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVt PjxyZW1vdGUtZGF0YWJhc2UtbmFtZT5QdWJNZWQ8L3JlbW90ZS1kYXRhYmFzZS1uYW1lPjxsYW5n dWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG== ADDIN EN.CITE.DATA (29, 30). اما در مطالعهی کنونی تفاوت معناداری از نظرسیگار کشیدن و اعتیاد بین دو گروه وجود نداشت؛ لذا نتیجهی مطالعهی ما بایستی با مطالعات دیگر در این زمینه نیز مقایسه شود. تغییرات در مقادیر آزمایشگاهی نیز در مبتلایان به کووید-19، بسته به شدت بیماری، مکرر و متنوع است ADDIN EN.CITE <EndNote><Cite><Author>Yang</Author><Year>2020</Year><RecNum>5</RecNum><DisplayText>(6)</DisplayText><record><rec-number>5</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">5</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Yang, Xiaobo</author><author>Yu, Yuan</author><author>Xu, Jiqian</author><author>Shu, Huaqing</author><author>Xia, Jia'an</author><author>Liu, Hong</author><author>Wu, Yongran</author><author>Zhang, Lu</author><author>Yu, Zhui</author><author>Fang, Minghao</author><author>Yu, Ting</author><author>Wang, Yaxin</author><author>Pan, Shangwen</author><author>Zou, Xiaojing</author><author>Yuan, Shiying</author><author>Shang, You</author></authors></contributors><titles><title>Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study</title><secondary-title>The Lancet Respiratory Medicine</secondary-title></titles><periodical><full-title>The Lancet Respiratory Medicine</full-title></periodical><pages>475-481</pages><volume>8</volume><number>5</number><dates><year>2020</year><pub-dates><date>2020/05/01/</date></pub-dates></dates><isbn>2213-2600</isbn><urls><related-urls><url>http://www.sciencedirect.com/science/article/pii/S2213260020300795</url></related-urls></urls><electronic-resource-num>https://doi.org/10.1016/S2213-2600(20)30079-5</electronic-resource-num></record></Cite></EndNote>(6).در مطالعهی حاضر از نظر کاهش میزان لنفوسیتها و افزایش در میزان نوتروفیلها بین دوگروه متوفی و بازمانده به لحاظ آماری تفاوت معناداری وجود داشت که با مطالعات تان و همکاران همسو بود. لنفوسیتها سلولهای ایمنی مهمی هستند؛ چرا که ویژگی پاسخ ایمنی را تعیین میکنند. دلیل کاهش تعداد لنفوسیتهای محیطی در بیماران کووید-19، مصرف بیش از حد سلولهای ایمنی ناشی از پاسخ ایمنی بیش‌ از حد و شدید است و به دنبال آن عملکرد ایمنی سلول در بیماران کاهش مییابد. بنابراین کاهش لنفوسیتها شاخص مهمی در ارزیابی شدت بیماران کووید-19 است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5UYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+ODA8L1JlY051bT48RGlzcGxheVRleHQ+KDMxKTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj44MDwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+ODA8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlRhbiwgTC48L2F1dGhvcj48YXV0aG9yPldhbmcsIFEu PC9hdXRob3I+PGF1dGhvcj5aaGFuZywgRC48L2F1dGhvcj48YXV0aG9yPkRpbmcsIEouPC9hdXRo b3I+PGF1dGhvcj5IdWFuZywgUS48L2F1dGhvcj48YXV0aG9yPlRhbmcsIFkuIFEuPC9hdXRob3I+ PGF1dGhvcj5XYW5nLCBRLjwvYXV0aG9yPjxhdXRob3I+TWlhbywgSC48L2F1dGhvcj48L2F1dGhv cnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5EZXBhcnRtZW50IG9mIERpc2Vhc2UgQ29u dHJvbCBhbmQgUHJldmVudGlvbiwgR2VuZXJhbCBIb3NwaXRhbCBvZiBDZW50cmFsIFRoZWF0ZXIg Q29tbWFuZCwgNDMwMDE1LCBXdWhhbiwgSHViZWkgcHJvdmluY2UsIFBlb3BsZSZhcG9zO3MgUmVw dWJsaWMgb2YgQ2hpbmEuJiN4RDtEZXBhcnRtZW50IG9mIExhYm9yYXRvcnksIEdlbmVyYWwgSG9z cGl0YWwgb2YgQ2VudHJhbCBUaGVhdGVyIENvbW1hbmQsIDQzMDAxNSwgV3VoYW4sIEh1YmVpIHBy b3ZpbmNlLCBQZW9wbGUmYXBvcztzIFJlcHVibGljIG9mIENoaW5hLiYjeEQ7TVJDIExhYm9yYXRv cnkgb2YgTW9sZWN1bGFyIEJpb2xvZ3ksIENhbWJyaWRnZSBCaW9tZWRpY2FsIENhbXB1cywgQ2Ft YnJpZGdlLCBDQjIgMFFILCBVSy4mI3hEO0RlcGFydG1lbnQgb2YgRGlzZWFzZSBDb250cm9sIGFu ZCBQcmV2ZW50aW9uLCBHZW5lcmFsIEhvc3BpdGFsIG9mIENlbnRyYWwgVGhlYXRlciBDb21tYW5k LCA0MzAwMTUsIFd1aGFuLCBIdWJlaSBwcm92aW5jZSwgUGVvcGxlJmFwb3M7cyBSZXB1YmxpYyBv ZiBDaGluYS4gd2h6eXl3cXNAMTYzLmNvbS4mI3hEO0RlcGFydG1lbnQgb2YgQmlvY2hlbWlzdHJ5 IGFuZCBNb2xlY3VsYXIgQmlvbG9neSwgVGhpcmQgTWlsaXRhcnkgTWVkaWNhbCBVbml2ZXJzaXR5 IChBcm15IE1lZGljYWwgVW5pdmVyc2l0eSksIDQwMDAzOCwgQ2hvbmdxaW5nLCBQZW9wbGUmYXBv cztzIFJlcHVibGljIG9mIENoaW5hLiBob25nbWluZ21pYW9Ac2luYS5jb20uPC9hdXRoLWFkZHJl c3M+PHRpdGxlcz48dGl0bGU+THltcGhvcGVuaWEgcHJlZGljdHMgZGlzZWFzZSBzZXZlcml0eSBv ZiBDT1ZJRC0xOTogYSBkZXNjcmlwdGl2ZSBhbmQgcHJlZGljdGl2ZSBzdHVkeTwvdGl0bGU+PHNl Y29uZGFyeS10aXRsZT5TaWduYWwgVHJhbnNkdWN0IFRhcmdldCBUaGVyPC9zZWNvbmRhcnktdGl0 bGU+PGFsdC10aXRsZT5TaWduYWwgdHJhbnNkdWN0aW9uIGFuZCB0YXJnZXRlZCB0aGVyYXB5PC9h bHQtdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+U2lnbmFsIFRyYW5zZHVj dCBUYXJnZXQgVGhlcjwvZnVsbC10aXRsZT48YWJici0xPlNpZ25hbCB0cmFuc2R1Y3Rpb24gYW5k IHRhcmdldGVkIHRoZXJhcHk8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxm dWxsLXRpdGxlPlNpZ25hbCBUcmFuc2R1Y3QgVGFyZ2V0IFRoZXI8L2Z1bGwtdGl0bGU+PGFiYnIt MT5TaWduYWwgdHJhbnNkdWN0aW9uIGFuZCB0YXJnZXRlZCB0aGVyYXB5PC9hYmJyLTE+PC9hbHQt cGVyaW9kaWNhbD48cGFnZXM+MzM8L3BhZ2VzPjx2b2x1bWU+NTwvdm9sdW1lPjxudW1iZXI+MTwv bnVtYmVyPjxlZGl0aW9uPjIwMjAvMDQvMTc8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkJl dGFjb3JvbmF2aXJ1cy8qcGF0aG9nZW5pY2l0eTwva2V5d29yZD48a2V5d29yZD5DaGluYTwva2V5 d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZlY3Rpb25zLypjb21wbGljYXRpb25zLypkaWFn bm9zaXMvbW9ydGFsaXR5L3BhdGhvbG9neTwva2V5d29yZD48a2V5d29yZD4qRGlzZWFzZSBQcm9n cmVzc2lvbjwva2V5d29yZD48a2V5d29yZD5Ib3NwaXRhbGl6YXRpb24vKnN0YXRpc3RpY3MgJmFt cDsgbnVtZXJpY2FsIGRhdGE8L2tleXdvcmQ+PGtleXdvcmQ+SHVtYW5zPC9rZXl3b3JkPjxrZXl3 b3JkPkx5bXBob2N5dGVzL21ldGFib2xpc20vcGF0aG9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPkx5 bXBob3BlbmlhLypjb21wbGljYXRpb25zLypkaWFnbm9zaXMvcGF0aG9sb2d5PC9rZXl3b3JkPjxr ZXl3b3JkPlBhbmRlbWljczwva2V5d29yZD48a2V5d29yZD5QZXB0aWR5bC1EaXBlcHRpZGFzZSBB L21ldGFib2xpc208L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC8qY29tcGxpY2F0 aW9ucy8qZGlhZ25vc2lzL21vcnRhbGl0eS9wYXRob2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+UHJh Y3RpY2UgR3VpZGVsaW5lcyBhcyBUb3BpYzwva2V5d29yZD48a2V5d29yZD5Qcm9nbm9zaXM8L2tl eXdvcmQ+PGtleXdvcmQ+UmVwcm9kdWNpYmlsaXR5IG9mIFJlc3VsdHM8L2tleXdvcmQ+PGtleXdv cmQ+VGltZSBGYWN0b3JzPC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIwMjA8L3ll YXI+PHB1Yi1kYXRlcz48ZGF0ZT5NYXIgMjc8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRlcz48aXNi bj4yMDk1LTk5MDcgKFByaW50KSYjeEQ7MjA1OS0zNjM1PC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMy Mjk2MDY5PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM3MTAwNDE5PC9j dXN0b20yPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDM4L3M0MTM5Mi0wMjAtMDE0OC00 PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPk5sbTwv cmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3Jk PjwvQ2l0ZT48L0VuZE5vdGU+AG== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5UYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+ODA8L1JlY051bT48RGlzcGxheVRleHQ+KDMxKTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj44MDwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+ODA8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlRhbiwgTC48L2F1dGhvcj48YXV0aG9yPldhbmcsIFEu PC9hdXRob3I+PGF1dGhvcj5aaGFuZywgRC48L2F1dGhvcj48YXV0aG9yPkRpbmcsIEouPC9hdXRo b3I+PGF1dGhvcj5IdWFuZywgUS48L2F1dGhvcj48YXV0aG9yPlRhbmcsIFkuIFEuPC9hdXRob3I+ PGF1dGhvcj5XYW5nLCBRLjwvYXV0aG9yPjxhdXRob3I+TWlhbywgSC48L2F1dGhvcj48L2F1dGhv cnM+PC9jb250cmlidXRvcnM+PGF1dGgtYWRkcmVzcz5EZXBhcnRtZW50IG9mIERpc2Vhc2UgQ29u dHJvbCBhbmQgUHJldmVudGlvbiwgR2VuZXJhbCBIb3NwaXRhbCBvZiBDZW50cmFsIFRoZWF0ZXIg Q29tbWFuZCwgNDMwMDE1LCBXdWhhbiwgSHViZWkgcHJvdmluY2UsIFBlb3BsZSZhcG9zO3MgUmVw dWJsaWMgb2YgQ2hpbmEuJiN4RDtEZXBhcnRtZW50IG9mIExhYm9yYXRvcnksIEdlbmVyYWwgSG9z cGl0YWwgb2YgQ2VudHJhbCBUaGVhdGVyIENvbW1hbmQsIDQzMDAxNSwgV3VoYW4sIEh1YmVpIHBy b3ZpbmNlLCBQZW9wbGUmYXBvcztzIFJlcHVibGljIG9mIENoaW5hLiYjeEQ7TVJDIExhYm9yYXRv cnkgb2YgTW9sZWN1bGFyIEJpb2xvZ3ksIENhbWJyaWRnZSBCaW9tZWRpY2FsIENhbXB1cywgQ2Ft YnJpZGdlLCBDQjIgMFFILCBVSy4mI3hEO0RlcGFydG1lbnQgb2YgRGlzZWFzZSBDb250cm9sIGFu ZCBQcmV2ZW50aW9uLCBHZW5lcmFsIEhvc3BpdGFsIG9mIENlbnRyYWwgVGhlYXRlciBDb21tYW5k LCA0MzAwMTUsIFd1aGFuLCBIdWJlaSBwcm92aW5jZSwgUGVvcGxlJmFwb3M7cyBSZXB1YmxpYyBv ZiBDaGluYS4gd2h6eXl3cXNAMTYzLmNvbS4mI3hEO0RlcGFydG1lbnQgb2YgQmlvY2hlbWlzdHJ5 IGFuZCBNb2xlY3VsYXIgQmlvbG9neSwgVGhpcmQgTWlsaXRhcnkgTWVkaWNhbCBVbml2ZXJzaXR5 IChBcm15IE1lZGljYWwgVW5pdmVyc2l0eSksIDQwMDAzOCwgQ2hvbmdxaW5nLCBQZW9wbGUmYXBv cztzIFJlcHVibGljIG9mIENoaW5hLiBob25nbWluZ21pYW9Ac2luYS5jb20uPC9hdXRoLWFkZHJl c3M+PHRpdGxlcz48dGl0bGU+THltcGhvcGVuaWEgcHJlZGljdHMgZGlzZWFzZSBzZXZlcml0eSBv ZiBDT1ZJRC0xOTogYSBkZXNjcmlwdGl2ZSBhbmQgcHJlZGljdGl2ZSBzdHVkeTwvdGl0bGU+PHNl Y29uZGFyeS10aXRsZT5TaWduYWwgVHJhbnNkdWN0IFRhcmdldCBUaGVyPC9zZWNvbmRhcnktdGl0 bGU+PGFsdC10aXRsZT5TaWduYWwgdHJhbnNkdWN0aW9uIGFuZCB0YXJnZXRlZCB0aGVyYXB5PC9h bHQtdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+U2lnbmFsIFRyYW5zZHVj dCBUYXJnZXQgVGhlcjwvZnVsbC10aXRsZT48YWJici0xPlNpZ25hbCB0cmFuc2R1Y3Rpb24gYW5k IHRhcmdldGVkIHRoZXJhcHk8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxm dWxsLXRpdGxlPlNpZ25hbCBUcmFuc2R1Y3QgVGFyZ2V0IFRoZXI8L2Z1bGwtdGl0bGU+PGFiYnIt MT5TaWduYWwgdHJhbnNkdWN0aW9uIGFuZCB0YXJnZXRlZCB0aGVyYXB5PC9hYmJyLTE+PC9hbHQt cGVyaW9kaWNhbD48cGFnZXM+MzM8L3BhZ2VzPjx2b2x1bWU+NTwvdm9sdW1lPjxudW1iZXI+MTwv bnVtYmVyPjxlZGl0aW9uPjIwMjAvMDQvMTc8L2VkaXRpb24+PGtleXdvcmRzPjxrZXl3b3JkPkJl dGFjb3JvbmF2aXJ1cy8qcGF0aG9nZW5pY2l0eTwva2V5d29yZD48a2V5d29yZD5DaGluYTwva2V5 d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZlY3Rpb25zLypjb21wbGljYXRpb25zLypkaWFn bm9zaXMvbW9ydGFsaXR5L3BhdGhvbG9neTwva2V5d29yZD48a2V5d29yZD4qRGlzZWFzZSBQcm9n cmVzc2lvbjwva2V5d29yZD48a2V5d29yZD5Ib3NwaXRhbGl6YXRpb24vKnN0YXRpc3RpY3MgJmFt cDsgbnVtZXJpY2FsIGRhdGE8L2tleXdvcmQ+PGtleXdvcmQ+SHVtYW5zPC9rZXl3b3JkPjxrZXl3 b3JkPkx5bXBob2N5dGVzL21ldGFib2xpc20vcGF0aG9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPkx5 bXBob3BlbmlhLypjb21wbGljYXRpb25zLypkaWFnbm9zaXMvcGF0aG9sb2d5PC9rZXl3b3JkPjxr ZXl3b3JkPlBhbmRlbWljczwva2V5d29yZD48a2V5d29yZD5QZXB0aWR5bC1EaXBlcHRpZGFzZSBB L21ldGFib2xpc208L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC8qY29tcGxpY2F0 aW9ucy8qZGlhZ25vc2lzL21vcnRhbGl0eS9wYXRob2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+UHJh Y3RpY2UgR3VpZGVsaW5lcyBhcyBUb3BpYzwva2V5d29yZD48a2V5d29yZD5Qcm9nbm9zaXM8L2tl eXdvcmQ+PGtleXdvcmQ+UmVwcm9kdWNpYmlsaXR5IG9mIFJlc3VsdHM8L2tleXdvcmQ+PGtleXdv cmQ+VGltZSBGYWN0b3JzPC9rZXl3b3JkPjwva2V5d29yZHM+PGRhdGVzPjx5ZWFyPjIwMjA8L3ll YXI+PHB1Yi1kYXRlcz48ZGF0ZT5NYXIgMjc8L2RhdGU+PC9wdWItZGF0ZXM+PC9kYXRlcz48aXNi bj4yMDk1LTk5MDcgKFByaW50KSYjeEQ7MjA1OS0zNjM1PC9pc2JuPjxhY2Nlc3Npb24tbnVtPjMy Mjk2MDY5PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjwvdXJscz48Y3VzdG9tMj5QbWM3MTAwNDE5PC9j dXN0b20yPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDM4L3M0MTM5Mi0wMjAtMDE0OC00 PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPk5sbTwv cmVtb3RlLWRhdGFiYXNlLXByb3ZpZGVyPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdlPjwvcmVjb3Jk PjwvQ2l0ZT48L0VuZE5vdGU+AG== ADDIN EN.CITE.DATA (31). همچنین افزایش سطح پروتئین واکنشی فاز حاد، سرعت رسوب گلبولقرمز و لاکتاتدهیدروژناز نیز می‌تواند برای تشخیص مفید باشد PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YaW9uZzwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT4xNTU8L1JlY051bT48RGlzcGxheVRleHQ+KDMyKTwvRGlzcGxheVRleHQ+PHJlY29yZD48 cmVjLW51bWJlcj4xNTU8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRi LWlkPSI5c2U1djB2dHZ4cjJmaGUwenYxeDlzZm1ycjI5cmZ4dnI5ZHQiPjE1NTwva2V5PjwvZm9y ZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48 Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+WGlvbmcsIFlpbmc8L2F1dGhvcj48YXV0aG9y PlN1biwgRG9uZzwvYXV0aG9yPjxhdXRob3I+TGl1LCBZYW88L2F1dGhvcj48YXV0aG9yPkZhbiwg WWFucWluZzwvYXV0aG9yPjxhdXRob3I+WmhhbywgTGluZ3l1bjwvYXV0aG9yPjxhdXRob3I+TGks IFhpYW9taW5nPC9hdXRob3I+PGF1dGhvcj5aaHUsIFdlbnpoZW48L2F1dGhvcj48L2F1dGhvcnM+ PC9jb250cmlidXRvcnM+PHRpdGxlcz48dGl0bGU+Q2xpbmljYWwgYW5kIEhpZ2gtUmVzb2x1dGlv biBDVCBGZWF0dXJlcyBvZiB0aGUgQ09WSUQtMTkgSW5mZWN0aW9uOiBDb21wYXJpc29uIG9mIHRo ZSBJbml0aWFsIGFuZCBGb2xsb3ctdXAgQ2hhbmdlczwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5J bnZlc3RpZ2F0aXZlIHJhZGlvbG9neTwvc2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+SW52ZXN0 IFJhZGlvbDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkludmVz dGlnYXRpdmUgcmFkaW9sb2d5PC9mdWxsLXRpdGxlPjxhYmJyLTE+SW52ZXN0IFJhZGlvbDwvYWJi ci0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+SW52ZXN0aWdhdGl2 ZSByYWRpb2xvZ3k8L2Z1bGwtdGl0bGU+PGFiYnItMT5JbnZlc3QgUmFkaW9sPC9hYmJyLTE+PC9h bHQtcGVyaW9kaWNhbD48cGFnZXM+MzMyLTMzOTwvcGFnZXM+PHZvbHVtZT41NTwvdm9sdW1lPjxu dW1iZXI+NjwvbnVtYmVyPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5d29yZD48a2V5d29y ZD5CZXRhY29yb25hdmlydXM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdv cmQ+Q29yb25hdmlydXMgSW5mZWN0aW9ucy8qZGlhZ25vc3RpYyBpbWFnaW5nL3RoZXJhcHk8L2tl eXdvcmQ+PGtleXdvcmQ+RGlzZWFzZSBQcm9ncmVzc2lvbjwva2V5d29yZD48a2V5d29yZD5GZW1h bGU8L2tleXdvcmQ+PGtleXdvcmQ+Rm9sbG93LVVwIFN0dWRpZXM8L2tleXdvcmQ+PGtleXdvcmQ+ SHVtYW5zPC9rZXl3b3JkPjxrZXl3b3JkPkxpbmVhciBNb2RlbHM8L2tleXdvcmQ+PGtleXdvcmQ+ THVuZy8qZGlhZ25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPk1hbGU8L2tleXdvcmQ+ PGtleXdvcmQ+TWlkZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+UGFuZGVtaWNzPC9rZXl3b3Jk PjxrZXl3b3JkPlBuZXVtb25pYSwgVmlyYWwvKmRpYWdub3N0aWMgaW1hZ2luZy90aGVyYXB5PC9r ZXl3b3JkPjxrZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD5U aG9yYXgvZGlhZ25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPlRvbW9ncmFwaHksIFgt UmF5IENvbXB1dGVkL21ldGhvZHM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAy MDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+TGlwcGluY290dCBXaWxsaWFtcyAmYW1wOyBXaWxr aW5zPC9wdWJsaXNoZXI+PGlzYm4+MTUzNi0wMjEwJiN4RDswMDIwLTk5OTY8L2lzYm4+PGFjY2Vz c2lvbi1udW0+MzIxMzQ4MDA8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJs Pmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQ4MDA8L3VybD48dXJsPmh0dHBz Oi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcxNDcyODIvPC91cmw+PC9y ZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDk3L1JMSS4w MDAwMDAwMDAwMDAwNjc0PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRhdGFiYXNl LW5hbWU+UHViTWVkPC9yZW1vdGUtZGF0YWJhc2UtbmFtZT48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFn ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YaW9uZzwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT4xNTU8L1JlY051bT48RGlzcGxheVRleHQ+KDMyKTwvRGlzcGxheVRleHQ+PHJlY29yZD48 cmVjLW51bWJlcj4xNTU8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0iRU4iIGRi LWlkPSI5c2U1djB2dHZ4cjJmaGUwenYxeDlzZm1ycjI5cmZ4dnI5ZHQiPjE1NTwva2V5PjwvZm9y ZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48 Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+WGlvbmcsIFlpbmc8L2F1dGhvcj48YXV0aG9y PlN1biwgRG9uZzwvYXV0aG9yPjxhdXRob3I+TGl1LCBZYW88L2F1dGhvcj48YXV0aG9yPkZhbiwg WWFucWluZzwvYXV0aG9yPjxhdXRob3I+WmhhbywgTGluZ3l1bjwvYXV0aG9yPjxhdXRob3I+TGks IFhpYW9taW5nPC9hdXRob3I+PGF1dGhvcj5aaHUsIFdlbnpoZW48L2F1dGhvcj48L2F1dGhvcnM+ PC9jb250cmlidXRvcnM+PHRpdGxlcz48dGl0bGU+Q2xpbmljYWwgYW5kIEhpZ2gtUmVzb2x1dGlv biBDVCBGZWF0dXJlcyBvZiB0aGUgQ09WSUQtMTkgSW5mZWN0aW9uOiBDb21wYXJpc29uIG9mIHRo ZSBJbml0aWFsIGFuZCBGb2xsb3ctdXAgQ2hhbmdlczwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5J bnZlc3RpZ2F0aXZlIHJhZGlvbG9neTwvc2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0bGU+SW52ZXN0 IFJhZGlvbDwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPkludmVz dGlnYXRpdmUgcmFkaW9sb2d5PC9mdWxsLXRpdGxlPjxhYmJyLTE+SW52ZXN0IFJhZGlvbDwvYWJi ci0xPjwvcGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+SW52ZXN0aWdhdGl2 ZSByYWRpb2xvZ3k8L2Z1bGwtdGl0bGU+PGFiYnItMT5JbnZlc3QgUmFkaW9sPC9hYmJyLTE+PC9h bHQtcGVyaW9kaWNhbD48cGFnZXM+MzMyLTMzOTwvcGFnZXM+PHZvbHVtZT41NTwvdm9sdW1lPjxu dW1iZXI+NjwvbnVtYmVyPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5d29yZD48a2V5d29y ZD5CZXRhY29yb25hdmlydXM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdv cmQ+Q29yb25hdmlydXMgSW5mZWN0aW9ucy8qZGlhZ25vc3RpYyBpbWFnaW5nL3RoZXJhcHk8L2tl eXdvcmQ+PGtleXdvcmQ+RGlzZWFzZSBQcm9ncmVzc2lvbjwva2V5d29yZD48a2V5d29yZD5GZW1h bGU8L2tleXdvcmQ+PGtleXdvcmQ+Rm9sbG93LVVwIFN0dWRpZXM8L2tleXdvcmQ+PGtleXdvcmQ+ SHVtYW5zPC9rZXl3b3JkPjxrZXl3b3JkPkxpbmVhciBNb2RlbHM8L2tleXdvcmQ+PGtleXdvcmQ+ THVuZy8qZGlhZ25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPk1hbGU8L2tleXdvcmQ+ PGtleXdvcmQ+TWlkZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+UGFuZGVtaWNzPC9rZXl3b3Jk PjxrZXl3b3JkPlBuZXVtb25pYSwgVmlyYWwvKmRpYWdub3N0aWMgaW1hZ2luZy90aGVyYXB5PC9r ZXl3b3JkPjxrZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD5U aG9yYXgvZGlhZ25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPlRvbW9ncmFwaHksIFgt UmF5IENvbXB1dGVkL21ldGhvZHM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAy MDwveWVhcj48L2RhdGVzPjxwdWJsaXNoZXI+TGlwcGluY290dCBXaWxsaWFtcyAmYW1wOyBXaWxr aW5zPC9wdWJsaXNoZXI+PGlzYm4+MTUzNi0wMjEwJiN4RDswMDIwLTk5OTY8L2lzYm4+PGFjY2Vz c2lvbi1udW0+MzIxMzQ4MDA8L2FjY2Vzc2lvbi1udW0+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJs Pmh0dHBzOi8vcHVibWVkLm5jYmkubmxtLm5paC5nb3YvMzIxMzQ4MDA8L3VybD48dXJsPmh0dHBz Oi8vd3d3Lm5jYmkubmxtLm5paC5nb3YvcG1jL2FydGljbGVzL1BNQzcxNDcyODIvPC91cmw+PC9y ZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDk3L1JMSS4w MDAwMDAwMDAwMDAwNjc0PC9lbGVjdHJvbmljLXJlc291cmNlLW51bT48cmVtb3RlLWRhdGFiYXNl LW5hbWU+UHViTWVkPC9yZW1vdGUtZGF0YWJhc2UtbmFtZT48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFn ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn== ADDIN EN.CITE.DATA (32). در مطالعهی ما نیز افزایش در این مقادیر بین دو گروه متوفی و بازمانده به لحاظ آماری معنادار بود که این نتایج با مطالعات دیگر همسو بود PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YaW9uZzwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT44MTwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTcsIDMzKTwvRGlzcGxheVRleHQ+PHJlY29y ZD48cmVjLW51bWJlcj44MTwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIg ZGItaWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+ODE8L2tleT48L2Zv cmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+ PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlhpb25nLCBZLjwvYXV0aG9yPjxhdXRob3I+ U3VuLCBELjwvYXV0aG9yPjxhdXRob3I+TGl1LCBZLjwvYXV0aG9yPjxhdXRob3I+RmFuLCBZLjwv YXV0aG9yPjxhdXRob3I+WmhhbywgTC48L2F1dGhvcj48YXV0aG9yPkxpLCBYLjwvYXV0aG9yPjxh dXRob3I+Wmh1LCBXLjwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48YXV0aC1hZGRy ZXNzPkZyb20gdGhlIERlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBUb25namkgSG9zcGl0YWwsIFRv bmdqaSBNZWRpY2FsIENvbGxlZ2UsIEh1YXpob25nIFVuaXZlcnNpdHkgb2YgU2NpZW5jZSBhbmQg VGVjaG5vbG9neS4mI3hEO0RlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBKaW4gWWluLVRhbiBIb3Nw aXRhbCwgV3VoYW4sIENoaW5hLjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2Fs IGFuZCBIaWdoLVJlc29sdXRpb24gQ1QgRmVhdHVyZXMgb2YgdGhlIENPVklELTE5IEluZmVjdGlv bjogQ29tcGFyaXNvbiBvZiB0aGUgSW5pdGlhbCBhbmQgRm9sbG93LXVwIENoYW5nZXM8L3RpdGxl PjxzZWNvbmRhcnktdGl0bGU+SW52ZXN0IFJhZGlvbDwvc2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0 bGU+SW52ZXN0aWdhdGl2ZSByYWRpb2xvZ3k8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNh bD48ZnVsbC10aXRsZT5JbnZlc3QgUmFkaW9sPC9mdWxsLXRpdGxlPjxhYmJyLTE+SW52ZXN0aWdh dGl2ZSByYWRpb2xvZ3k8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxmdWxs LXRpdGxlPkludmVzdCBSYWRpb2w8L2Z1bGwtdGl0bGU+PGFiYnItMT5JbnZlc3RpZ2F0aXZlIHJh ZGlvbG9neTwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+PHBhZ2VzPjMzMi0zMzk8L3BhZ2VzPjx2 b2x1bWU+NTU8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzA3PC9l ZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5d29yZD48a2V5d29yZD5CZXRhY29y b25hdmlydXM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdvcmQ+Q29yb25h dmlydXMgSW5mZWN0aW9ucy8qZGlhZ25vc3RpYyBpbWFnaW5nL3RoZXJhcHk8L2tleXdvcmQ+PGtl eXdvcmQ+RGlzZWFzZSBQcm9ncmVzc2lvbjwva2V5d29yZD48a2V5d29yZD5GZW1hbGU8L2tleXdv cmQ+PGtleXdvcmQ+Rm9sbG93LVVwIFN0dWRpZXM8L2tleXdvcmQ+PGtleXdvcmQ+SHVtYW5zPC9r ZXl3b3JkPjxrZXl3b3JkPkxpbmVhciBNb2RlbHM8L2tleXdvcmQ+PGtleXdvcmQ+THVuZy8qZGlh Z25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPk1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+ TWlkZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+UGFuZGVtaWNzPC9rZXl3b3JkPjxrZXl3b3Jk PlBuZXVtb25pYSwgVmlyYWwvKmRpYWdub3N0aWMgaW1hZ2luZy90aGVyYXB5PC9rZXl3b3JkPjxr ZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD5UaG9yYXgvZGlh Z25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPlRvbW9ncmFwaHksIFgtUmF5IENvbXB1 dGVkL21ldGhvZHM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48 cHViLWRhdGVzPjxkYXRlPkp1bjwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjAwMjAt OTk5NiAoUHJpbnQpJiN4RDswMDIwLTk5OTY8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIxMzQ4MDA8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0b20yPlBtYzcxNDcyODI8L2N1c3RvbTI+ PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwOTcvcmxpLjAwMDAwMDAwMDAwMDA2NzQ8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1v dGUtZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9D aXRlPjxDaXRlPjxBdXRob3I+U3VuPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVjTnVtPjUy PC9SZWNOdW0+PHJlY29yZD48cmVjLW51bWJlcj41MjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlz PjxrZXkgYXBwPSJFTiIgZGItaWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRl ZCI+NTI8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlN1biwgWWluZzwv YXV0aG9yPjxhdXRob3I+RG9uZywgWWFubGk8L2F1dGhvcj48YXV0aG9yPldhbmcsIExpZmVuZzwv YXV0aG9yPjxhdXRob3I+WGllLCBIdWFuPC9hdXRob3I+PGF1dGhvcj5MaSwgQmFvc2VuPC9hdXRo b3I+PGF1dGhvcj5DaGFuZywgQ2hyaXN0b3BoZXI8L2F1dGhvcj48YXV0aG9yPldhbmcsIEZ1LVNo ZW5nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkNoYXJh Y3RlcmlzdGljcyBhbmQgcHJvZ25vc3RpYyBmYWN0b3JzIG9mIGRpc2Vhc2Ugc2V2ZXJpdHkgaW4g cGF0aWVudHMgd2l0aCBDT1ZJRC0xOTogVGhlIEJlaWppbmcgZXhwZXJpZW5jZTwvdGl0bGU+PHNl Y29uZGFyeS10aXRsZT5Kb3VybmFsIG9mIGF1dG9pbW11bml0eTwvc2Vjb25kYXJ5LXRpdGxlPjxh bHQtdGl0bGU+SiBBdXRvaW1tdW48L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVs bC10aXRsZT5Kb3VybmFsIG9mIGF1dG9pbW11bml0eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0 b2ltbXVuPC9hYmJyLTE+PC9wZXJpb2RpY2FsPjxhbHQtcGVyaW9kaWNhbD48ZnVsbC10aXRsZT5K b3VybmFsIG9mIGF1dG9pbW11bml0eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0b2ltbXVuPC9h YmJyLTE+PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+MTAyNDczLTEwMjQ3MzwvcGFnZXM+PHZvbHVt ZT4xMTI8L3ZvbHVtZT48ZWRpdGlvbj4wNC8yNDwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+ KjIwMTkgbm92ZWwgY29yb25hdmlydXMgZGlzZWFzZTwva2V5d29yZD48a2V5d29yZD4qQ09WSUQt MTk8L2tleXdvcmQ+PGtleXdvcmQ+KkN5dG9raW5lIHN0b3JtPC9rZXl3b3JkPjxrZXl3b3JkPipF bGV2YXRlZCBsaXZlciBlbnp5bWVzPC9rZXl3b3JkPjxrZXl3b3JkPipJbnRlcmxldWtpbi02PC9r ZXl3b3JkPjxrZXl3b3JkPipMeW1waG9jeXRlIHN1YnNldHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk1v cnRhbGl0eTwva2V5d29yZD48a2V5d29yZD4qUHJvZ25vc2lzPC9rZXl3b3JkPjxrZXl3b3JkPipT QVJTLUNvVi0yPC9rZXl3b3JkPjxrZXl3b3JkPkFkb2xlc2NlbnQ8L2tleXdvcmQ+PGtleXdvcmQ+ QWR1bHQ8L2tleXdvcmQ+PGtleXdvcmQ+QWdlZDwva2V5d29yZD48a2V5d29yZD5BZ2VkLCA4MCBh bmQgb3Zlcjwva2V5d29yZD48a2V5d29yZD5CZXRhY29yb25hdmlydXMvKm1ldGFib2xpc208L2tl eXdvcmQ+PGtleXdvcmQ+QmlvbWFya2Vycy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5DaGlsZDwv a2V5d29yZD48a2V5d29yZD5DaGlsZCwgUHJlc2Nob29sPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5h L2VwaWRlbWlvbG9neTwva2V5d29yZD48a2V5d29yZD4qQ29yb25hdmlydXMgSW5mZWN0aW9ucy9i bG9vZC9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3 b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5MZXVrb2N5dGUgQ291bnQ8L2tleXdvcmQ+PGtl eXdvcmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29y ZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxrZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2Jsb29kL2Vw aWRlbWlvbG9neTwva2V5d29yZD48a2V5d29yZD4qU2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwv a2V5d29yZD48a2V5d29yZD5TZXggRmFjdG9yczwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48 eWVhcj4yMDIwPC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5QdWJsaXNoZWQgYnkgRWxzZXZpZXIg THRkLjwvcHVibGlzaGVyPjxpc2JuPjEwOTUtOTE1NyYjeEQ7MDg5Ni04NDExPC9pc2JuPjxhY2Nl c3Npb24tbnVtPjMyNDM5MjA5PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjxyZWxhdGVkLXVybHM+PHVy bD5odHRwczovL3B1Ym1lZC5uY2JpLm5sbS5uaWguZ292LzMyNDM5MjA5PC91cmw+PHVybD5odHRw czovL3d3dy5uY2JpLm5sbS5uaWguZ292L3BtYy9hcnRpY2xlcy9QTUM3MTgwMzc2LzwvdXJsPjwv cmVsYXRlZC11cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9qLmph dXQuMjAyMC4xMDI0NzM8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2Ut bmFtZT5QdWJNZWQ8L3JlbW90ZS1kYXRhYmFzZS1uYW1lPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdl PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5YaW9uZzwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJl Y051bT44MTwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMTcsIDMzKTwvRGlzcGxheVRleHQ+PHJlY29y ZD48cmVjLW51bWJlcj44MTwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIg ZGItaWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+ODE8L2tleT48L2Zv cmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+ PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlhpb25nLCBZLjwvYXV0aG9yPjxhdXRob3I+ U3VuLCBELjwvYXV0aG9yPjxhdXRob3I+TGl1LCBZLjwvYXV0aG9yPjxhdXRob3I+RmFuLCBZLjwv YXV0aG9yPjxhdXRob3I+WmhhbywgTC48L2F1dGhvcj48YXV0aG9yPkxpLCBYLjwvYXV0aG9yPjxh dXRob3I+Wmh1LCBXLjwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48YXV0aC1hZGRy ZXNzPkZyb20gdGhlIERlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBUb25namkgSG9zcGl0YWwsIFRv bmdqaSBNZWRpY2FsIENvbGxlZ2UsIEh1YXpob25nIFVuaXZlcnNpdHkgb2YgU2NpZW5jZSBhbmQg VGVjaG5vbG9neS4mI3hEO0RlcGFydG1lbnQgb2YgUmFkaW9sb2d5LCBKaW4gWWluLVRhbiBIb3Nw aXRhbCwgV3VoYW4sIENoaW5hLjwvYXV0aC1hZGRyZXNzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2Fs IGFuZCBIaWdoLVJlc29sdXRpb24gQ1QgRmVhdHVyZXMgb2YgdGhlIENPVklELTE5IEluZmVjdGlv bjogQ29tcGFyaXNvbiBvZiB0aGUgSW5pdGlhbCBhbmQgRm9sbG93LXVwIENoYW5nZXM8L3RpdGxl PjxzZWNvbmRhcnktdGl0bGU+SW52ZXN0IFJhZGlvbDwvc2Vjb25kYXJ5LXRpdGxlPjxhbHQtdGl0 bGU+SW52ZXN0aWdhdGl2ZSByYWRpb2xvZ3k8L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNh bD48ZnVsbC10aXRsZT5JbnZlc3QgUmFkaW9sPC9mdWxsLXRpdGxlPjxhYmJyLTE+SW52ZXN0aWdh dGl2ZSByYWRpb2xvZ3k8L2FiYnItMT48L3BlcmlvZGljYWw+PGFsdC1wZXJpb2RpY2FsPjxmdWxs LXRpdGxlPkludmVzdCBSYWRpb2w8L2Z1bGwtdGl0bGU+PGFiYnItMT5JbnZlc3RpZ2F0aXZlIHJh ZGlvbG9neTwvYWJici0xPjwvYWx0LXBlcmlvZGljYWw+PHBhZ2VzPjMzMi0zMzk8L3BhZ2VzPjx2 b2x1bWU+NTU8L3ZvbHVtZT48bnVtYmVyPjY8L251bWJlcj48ZWRpdGlvbj4yMDIwLzAzLzA3PC9l ZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5d29yZD48a2V5d29yZD5CZXRhY29y b25hdmlydXM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmE8L2tleXdvcmQ+PGtleXdvcmQ+Q29yb25h dmlydXMgSW5mZWN0aW9ucy8qZGlhZ25vc3RpYyBpbWFnaW5nL3RoZXJhcHk8L2tleXdvcmQ+PGtl eXdvcmQ+RGlzZWFzZSBQcm9ncmVzc2lvbjwva2V5d29yZD48a2V5d29yZD5GZW1hbGU8L2tleXdv cmQ+PGtleXdvcmQ+Rm9sbG93LVVwIFN0dWRpZXM8L2tleXdvcmQ+PGtleXdvcmQ+SHVtYW5zPC9r ZXl3b3JkPjxrZXl3b3JkPkxpbmVhciBNb2RlbHM8L2tleXdvcmQ+PGtleXdvcmQ+THVuZy8qZGlh Z25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPk1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+ TWlkZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+UGFuZGVtaWNzPC9rZXl3b3JkPjxrZXl3b3Jk PlBuZXVtb25pYSwgVmlyYWwvKmRpYWdub3N0aWMgaW1hZ2luZy90aGVyYXB5PC9rZXl3b3JkPjxr ZXl3b3JkPlJldHJvc3BlY3RpdmUgU3R1ZGllczwva2V5d29yZD48a2V5d29yZD5UaG9yYXgvZGlh Z25vc3RpYyBpbWFnaW5nPC9rZXl3b3JkPjxrZXl3b3JkPlRvbW9ncmFwaHksIFgtUmF5IENvbXB1 dGVkL21ldGhvZHM8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48 cHViLWRhdGVzPjxkYXRlPkp1bjwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjAwMjAt OTk5NiAoUHJpbnQpJiN4RDswMDIwLTk5OTY8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIxMzQ4MDA8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0b20yPlBtYzcxNDcyODI8L2N1c3RvbTI+ PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwOTcvcmxpLjAwMDAwMDAwMDAwMDA2NzQ8L2Vs ZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1v dGUtZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9D aXRlPjxDaXRlPjxBdXRob3I+U3VuPC9BdXRob3I+PFllYXI+MjAyMDwvWWVhcj48UmVjTnVtPjUy PC9SZWNOdW0+PHJlY29yZD48cmVjLW51bWJlcj41MjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlz PjxrZXkgYXBwPSJFTiIgZGItaWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRl ZCI+NTI8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPlN1biwgWWluZzwv YXV0aG9yPjxhdXRob3I+RG9uZywgWWFubGk8L2F1dGhvcj48YXV0aG9yPldhbmcsIExpZmVuZzwv YXV0aG9yPjxhdXRob3I+WGllLCBIdWFuPC9hdXRob3I+PGF1dGhvcj5MaSwgQmFvc2VuPC9hdXRo b3I+PGF1dGhvcj5DaGFuZywgQ2hyaXN0b3BoZXI8L2F1dGhvcj48YXV0aG9yPldhbmcsIEZ1LVNo ZW5nPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkNoYXJh Y3RlcmlzdGljcyBhbmQgcHJvZ25vc3RpYyBmYWN0b3JzIG9mIGRpc2Vhc2Ugc2V2ZXJpdHkgaW4g cGF0aWVudHMgd2l0aCBDT1ZJRC0xOTogVGhlIEJlaWppbmcgZXhwZXJpZW5jZTwvdGl0bGU+PHNl Y29uZGFyeS10aXRsZT5Kb3VybmFsIG9mIGF1dG9pbW11bml0eTwvc2Vjb25kYXJ5LXRpdGxlPjxh bHQtdGl0bGU+SiBBdXRvaW1tdW48L2FsdC10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVs bC10aXRsZT5Kb3VybmFsIG9mIGF1dG9pbW11bml0eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0 b2ltbXVuPC9hYmJyLTE+PC9wZXJpb2RpY2FsPjxhbHQtcGVyaW9kaWNhbD48ZnVsbC10aXRsZT5K b3VybmFsIG9mIGF1dG9pbW11bml0eTwvZnVsbC10aXRsZT48YWJici0xPkogQXV0b2ltbXVuPC9h YmJyLTE+PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+MTAyNDczLTEwMjQ3MzwvcGFnZXM+PHZvbHVt ZT4xMTI8L3ZvbHVtZT48ZWRpdGlvbj4wNC8yNDwvZWRpdGlvbj48a2V5d29yZHM+PGtleXdvcmQ+ KjIwMTkgbm92ZWwgY29yb25hdmlydXMgZGlzZWFzZTwva2V5d29yZD48a2V5d29yZD4qQ09WSUQt MTk8L2tleXdvcmQ+PGtleXdvcmQ+KkN5dG9raW5lIHN0b3JtPC9rZXl3b3JkPjxrZXl3b3JkPipF bGV2YXRlZCBsaXZlciBlbnp5bWVzPC9rZXl3b3JkPjxrZXl3b3JkPipJbnRlcmxldWtpbi02PC9r ZXl3b3JkPjxrZXl3b3JkPipMeW1waG9jeXRlIHN1YnNldHM8L2tleXdvcmQ+PGtleXdvcmQ+Kk1v cnRhbGl0eTwva2V5d29yZD48a2V5d29yZD4qUHJvZ25vc2lzPC9rZXl3b3JkPjxrZXl3b3JkPipT QVJTLUNvVi0yPC9rZXl3b3JkPjxrZXl3b3JkPkFkb2xlc2NlbnQ8L2tleXdvcmQ+PGtleXdvcmQ+ QWR1bHQ8L2tleXdvcmQ+PGtleXdvcmQ+QWdlZDwva2V5d29yZD48a2V5d29yZD5BZ2VkLCA4MCBh bmQgb3Zlcjwva2V5d29yZD48a2V5d29yZD5CZXRhY29yb25hdmlydXMvKm1ldGFib2xpc208L2tl eXdvcmQ+PGtleXdvcmQ+QmlvbWFya2Vycy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5DaGlsZDwv a2V5d29yZD48a2V5d29yZD5DaGlsZCwgUHJlc2Nob29sPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5h L2VwaWRlbWlvbG9neTwva2V5d29yZD48a2V5d29yZD4qQ29yb25hdmlydXMgSW5mZWN0aW9ucy9i bG9vZC9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3 b3JkPkh1bWFuczwva2V5d29yZD48a2V5d29yZD5MZXVrb2N5dGUgQ291bnQ8L2tleXdvcmQ+PGtl eXdvcmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29y ZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxrZXl3b3JkPipQbmV1bW9uaWEsIFZpcmFsL2Jsb29kL2Vw aWRlbWlvbG9neTwva2V5d29yZD48a2V5d29yZD4qU2V2ZXJpdHkgb2YgSWxsbmVzcyBJbmRleDwv a2V5d29yZD48a2V5d29yZD5TZXggRmFjdG9yczwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48 eWVhcj4yMDIwPC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5QdWJsaXNoZWQgYnkgRWxzZXZpZXIg THRkLjwvcHVibGlzaGVyPjxpc2JuPjEwOTUtOTE1NyYjeEQ7MDg5Ni04NDExPC9pc2JuPjxhY2Nl c3Npb24tbnVtPjMyNDM5MjA5PC9hY2Nlc3Npb24tbnVtPjx1cmxzPjxyZWxhdGVkLXVybHM+PHVy bD5odHRwczovL3B1Ym1lZC5uY2JpLm5sbS5uaWguZ292LzMyNDM5MjA5PC91cmw+PHVybD5odHRw czovL3d3dy5uY2JpLm5sbS5uaWguZ292L3BtYy9hcnRpY2xlcy9QTUM3MTgwMzc2LzwvdXJsPjwv cmVsYXRlZC11cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9qLmph dXQuMjAyMC4xMDI0NzM8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2Ut bmFtZT5QdWJNZWQ8L3JlbW90ZS1kYXRhYmFzZS1uYW1lPjxsYW5ndWFnZT5lbmc8L2xhbmd1YWdl PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+ ADDIN EN.CITE.DATA (17, 33). در مطالعهی حاضر افزایش در مقادیر آزمایشگاهی PT و PTT در دو گروه متوفی و بازمانده تفاوت معناداری وجود نداشت که این یافته برخلاف مطالعه انجام شده توسط وان و همکاران (2020) است که مقادیر PT و PTT در بیماران نیازمند به بستری در بخش مراقبت ویژه در مقایسه با سایر بیماران بیشتر بوده‌است ADDIN EN.CITE <EndNote><Cite><Author>Wan</Author><Year>2020</Year><RecNum>3</RecNum><DisplayText>(34)</DisplayText><record><rec-number>3</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">3</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Wan, Suxin</author><author>Xiang, Yi</author><author>Fang, Wei</author><author>Zheng, Yu</author><author>Li, Boqun</author><author>Hu, Yanjun</author><author>Lang, Chunhui</author><author>Huang, Daoqiu</author><author>Sun, Qiuyan</author><author>Xiong, Yan</author><author>Huang, Xia</author><author>Lv, Jinglong</author><author>Luo, Yaling</author><author>Shen, Li</author><author>Yang, Haoran</author><author>Huang, Gu</author><author>Yang, Ruishan</author></authors></contributors><titles><title>Clinical features and treatment of COVID-19 patients in northeast Chongqing</title><secondary-title>Journal of Medical Virology</secondary-title></titles><periodical><full-title>Journal of Medical Virology</full-title></periodical><pages>797-806</pages><volume>92</volume><number>7</number><keywords><keyword>clinical features</keyword><keyword>cognition</keyword><keyword>COVID-19</keyword><keyword>northeast Chongqing</keyword><keyword>treatment</keyword></keywords><dates><year>2020</year><pub-dates><date>2020/07/01</date></pub-dates></dates><publisher>John Wiley & Sons, Ltd</publisher><isbn>0146-6615</isbn><urls><related-urls><url>https://doi.org/10.1002/jmv.25783</url></related-urls></urls><electronic-resource-num>10.1002/jmv.25783</electronic-resource-num><access-date>2020/09/02</access-date></record></Cite></EndNote>(34).در مطالعهی حاضر متوسط مقادیر آزمایشگاهی آسپارات تراسفراز و آلانین ترانسفراز در بیماران افزایش یافته بود اما از لحاظ آماری تفاوت معناداری بین دوگروه وجود نداشت. این در حالی است که در مطالعهی وانگ و همکاران (2020) علاوه بر افزایش این مقادیر آزمایشگاهی در بین گروه فوت شده در مقایسه با افراد بازمانده معنادار بود ADDIN EN.CITE <EndNote><Cite><Author>Wang</Author><Year>2020</Year><RecNum>164</RecNum><DisplayText>(35)</DisplayText><record><rec-number>164</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">164</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Wang, Kun</author><author>Zuo, Peiyuan</author><author>Liu, Yuwei</author><author>Zhang, Meng</author><author>Zhao, Xiaofang</author><author>Xie, Songpu</author><author>Zhang, Hao</author><author>Chen, Xinglin</author><author>Liu, Chengyun</author></authors></contributors><titles><title>Clinical and laboratory predictors of in-hospital mortality in patients with COVID-19: a cohort study in Wuhan, China</title><secondary-title>Clinical infectious diseases</secondary-title></titles><periodical><full-title>Clinical Infectious Diseases</full-title></periodical><dates><year>2020</year></dates><urls></urls></record></Cite></EndNote>(35). اگرچه یافتهها نشان می‌دهند که سارسکووید-2 ممکن است منجر به عملکرد غیر طبیعی کبد شود، اما با این‌حال تاکنون، هیچ یافته‌ای برای تعیین اینکه آیا عملکرد غیر طبیعی کبد در بیماران کووید-19 ناشی از مصرف داروهاست یا خیر، وجود ندارد و با توجه به ماهیت بسیار مسری و بیماری‌زای سارس کووید-2 و شیوع بالای آسیب کبدی، یک ارزیابی سریع و دقیق از عملکرد کبد در مبتلایان کووید-19 به ضروری است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5GYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+NTc8L1JlY051bT48RGlzcGxheVRleHQ+KDE1KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj41NzwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTc8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPkZhbiwgWi48L2F1dGhvcj48YXV0aG9yPkNoZW4sIEwu PC9hdXRob3I+PGF1dGhvcj5MaSwgSi48L2F1dGhvcj48YXV0aG9yPkNoZW5nLCBYLjwvYXV0aG9y PjxhdXRob3I+WWFuZywgSi48L2F1dGhvcj48YXV0aG9yPlRpYW4sIEMuPC9hdXRob3I+PGF1dGhv cj5aaGFuZywgWS48L2F1dGhvcj48YXV0aG9yPkh1YW5nLCBTLjwvYXV0aG9yPjxhdXRob3I+TGl1 LCBaLjwvYXV0aG9yPjxhdXRob3I+Q2hlbmcsIEouPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJp YnV0b3JzPjxhdXRoLWFkZHJlc3M+RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRlcm9sb2d5IGFuZCBI ZXBhdG9sb2d5LCBTaGFuZ2hhaSBQdWJsaWMgSGVhbHRoIENsaW5pY2FsIENlbnRlciwgRnVkYW4g VW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRl cm9sb2d5LCBUaGUgU2hhbmdoYWkgVGVudGggUGVvcGxlJmFwb3M7cyBIb3NwaXRhbCBvZiBUb25n amkgVW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiBFbGVjdHJvbmljIGFkZHJlc3M6IGxpdXpo YW5qdTg4QDEyNi5jb20uJiN4RDtEZXBhcnRtZW50IG9mIEdhc3Ryb2VudGVyb2xvZ3kgYW5kIEhl cGF0b2xvZ3ksIFNoYW5naGFpIFB1YmxpYyBIZWFsdGggQ2xpbmljYWwgQ2VudGVyLCBGdWRhbiBV bml2ZXJzaXR5LCBTaGFuZ2hhaSwgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2hlbmdqaWxp bkBzaHBoYy5vcmcuY24uPC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+Q2xpbmljYWwgRmVh dHVyZXMgb2YgQ09WSUQtMTktUmVsYXRlZCBMaXZlciBGdW5jdGlvbmFsIEFibm9ybWFsaXR5PC90 aXRsZT48c2Vjb25kYXJ5LXRpdGxlPkNsaW4gR2FzdHJvZW50ZXJvbCBIZXBhdG9sPC9zZWNvbmRh cnktdGl0bGU+PGFsdC10aXRsZT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9s b2d5IDogdGhlIG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJp Y2FuIEdhc3Ryb2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FsdC10aXRsZT48L3RpdGxlcz48 cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5DbGluIEdhc3Ryb2VudGVyb2wgSGVwYXRvbDwvZnVsbC10 aXRsZT48YWJici0xPkNsaW5pY2FsIGdhc3Ryb2VudGVyb2xvZ3kgYW5kIGhlcGF0b2xvZ3kgOiB0 aGUgb2ZmaWNpYWwgY2xpbmljYWwgcHJhY3RpY2Ugam91cm5hbCBvZiB0aGUgQW1lcmljYW4gR2Fz dHJvZW50ZXJvbG9naWNhbCBBc3NvY2lhdGlvbjwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBl cmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2xpbiBHYXN0cm9lbnRlcm9sIEhlcGF0b2w8L2Z1bGwtdGl0 bGU+PGFiYnItMT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9sb2d5IDogdGhl IG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJpY2FuIEdhc3Ry b2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdl cz4xNTYxLTE1NjY8L3BhZ2VzPjx2b2x1bWU+MTg8L3ZvbHVtZT48bnVtYmVyPjc8L251bWJlcj48 ZWRpdGlvbj4yMDIwLzA0LzE0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5 d29yZD48a2V5d29yZD5BbnRpdmlyYWwgQWdlbnRzL3RoZXJhcGV1dGljIHVzZTwva2V5d29yZD48 a2V5d29yZD5CZXRhY29yb25hdmlydXMvKmlzb2xhdGlvbiAmYW1wOyBwdXJpZmljYXRpb248L2tl eXdvcmQ+PGtleXdvcmQ+QmlsaXJ1YmluL2Jsb29kPC9rZXl3b3JkPjxrZXl3b3JkPkJsb29kIENo ZW1pY2FsIEFuYWx5c2lzPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwva2V5 d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZlY3Rpb25zLypjb21wbGljYXRpb25zLypwYXRo b2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+RW56eW1lcy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5G ZW1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+SG9zcGl0YWxzPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFu czwva2V5d29yZD48a2V5d29yZD5MaXZlciBEaXNlYXNlcy9kcnVnIHRoZXJhcHkvKmVwaWRlbWlv bG9neS8qZXRpb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+KkxpdmVyIEZ1bmN0aW9uIFRlc3RzPC9r ZXl3b3JkPjxrZXl3b3JkPkxvcGluYXZpci90aGVyYXBldXRpYyB1c2U8L2tleXdvcmQ+PGtleXdv cmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29yZD5Q YW5kZW1pY3M8L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC8qY29tcGxpY2F0aW9u cy8qcGF0aG9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPlByZXZhbGVuY2U8L2tleXdvcmQ+PGtleXdv cmQ+UmV0cm9zcGVjdGl2ZSBTdHVkaWVzPC9rZXl3b3JkPjxrZXl3b3JkPlJpdG9uYXZpci90aGVy YXBldXRpYyB1c2U8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48 cHViLWRhdGVzPjxkYXRlPkp1bjwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjE1NDIt MzU2NSAoUHJpbnQpJiN4RDsxNTQyLTM1NjU8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIyODMzMjU8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0b20yPlBtYzcxOTQ4NjU8L2N1c3RvbTI+ PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwMTYvai5jZ2guMjAyMC4wNC4wMDI8L2VsZWN0 cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1vdGUt ZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9DaXRl PjwvRW5kTm90ZT5= ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5GYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+NTc8L1JlY051bT48RGlzcGxheVRleHQ+KDE1KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVj LW51bWJlcj41NzwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9 IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTc8L2tleT48L2ZvcmVpZ24t a2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNvbnRy aWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPkZhbiwgWi48L2F1dGhvcj48YXV0aG9yPkNoZW4sIEwu PC9hdXRob3I+PGF1dGhvcj5MaSwgSi48L2F1dGhvcj48YXV0aG9yPkNoZW5nLCBYLjwvYXV0aG9y PjxhdXRob3I+WWFuZywgSi48L2F1dGhvcj48YXV0aG9yPlRpYW4sIEMuPC9hdXRob3I+PGF1dGhv cj5aaGFuZywgWS48L2F1dGhvcj48YXV0aG9yPkh1YW5nLCBTLjwvYXV0aG9yPjxhdXRob3I+TGl1 LCBaLjwvYXV0aG9yPjxhdXRob3I+Q2hlbmcsIEouPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJp YnV0b3JzPjxhdXRoLWFkZHJlc3M+RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRlcm9sb2d5IGFuZCBI ZXBhdG9sb2d5LCBTaGFuZ2hhaSBQdWJsaWMgSGVhbHRoIENsaW5pY2FsIENlbnRlciwgRnVkYW4g VW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiYjeEQ7RGVwYXJ0bWVudCBvZiBHYXN0cm9lbnRl cm9sb2d5LCBUaGUgU2hhbmdoYWkgVGVudGggUGVvcGxlJmFwb3M7cyBIb3NwaXRhbCBvZiBUb25n amkgVW5pdmVyc2l0eSwgU2hhbmdoYWksIENoaW5hLiBFbGVjdHJvbmljIGFkZHJlc3M6IGxpdXpo YW5qdTg4QDEyNi5jb20uJiN4RDtEZXBhcnRtZW50IG9mIEdhc3Ryb2VudGVyb2xvZ3kgYW5kIEhl cGF0b2xvZ3ksIFNoYW5naGFpIFB1YmxpYyBIZWFsdGggQ2xpbmljYWwgQ2VudGVyLCBGdWRhbiBV bml2ZXJzaXR5LCBTaGFuZ2hhaSwgQ2hpbmEuIEVsZWN0cm9uaWMgYWRkcmVzczogY2hlbmdqaWxp bkBzaHBoYy5vcmcuY24uPC9hdXRoLWFkZHJlc3M+PHRpdGxlcz48dGl0bGU+Q2xpbmljYWwgRmVh dHVyZXMgb2YgQ09WSUQtMTktUmVsYXRlZCBMaXZlciBGdW5jdGlvbmFsIEFibm9ybWFsaXR5PC90 aXRsZT48c2Vjb25kYXJ5LXRpdGxlPkNsaW4gR2FzdHJvZW50ZXJvbCBIZXBhdG9sPC9zZWNvbmRh cnktdGl0bGU+PGFsdC10aXRsZT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9s b2d5IDogdGhlIG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJp Y2FuIEdhc3Ryb2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FsdC10aXRsZT48L3RpdGxlcz48 cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5DbGluIEdhc3Ryb2VudGVyb2wgSGVwYXRvbDwvZnVsbC10 aXRsZT48YWJici0xPkNsaW5pY2FsIGdhc3Ryb2VudGVyb2xvZ3kgYW5kIGhlcGF0b2xvZ3kgOiB0 aGUgb2ZmaWNpYWwgY2xpbmljYWwgcHJhY3RpY2Ugam91cm5hbCBvZiB0aGUgQW1lcmljYW4gR2Fz dHJvZW50ZXJvbG9naWNhbCBBc3NvY2lhdGlvbjwvYWJici0xPjwvcGVyaW9kaWNhbD48YWx0LXBl cmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2xpbiBHYXN0cm9lbnRlcm9sIEhlcGF0b2w8L2Z1bGwtdGl0 bGU+PGFiYnItMT5DbGluaWNhbCBnYXN0cm9lbnRlcm9sb2d5IGFuZCBoZXBhdG9sb2d5IDogdGhl IG9mZmljaWFsIGNsaW5pY2FsIHByYWN0aWNlIGpvdXJuYWwgb2YgdGhlIEFtZXJpY2FuIEdhc3Ry b2VudGVyb2xvZ2ljYWwgQXNzb2NpYXRpb248L2FiYnItMT48L2FsdC1wZXJpb2RpY2FsPjxwYWdl cz4xNTYxLTE1NjY8L3BhZ2VzPjx2b2x1bWU+MTg8L3ZvbHVtZT48bnVtYmVyPjc8L251bWJlcj48 ZWRpdGlvbj4yMDIwLzA0LzE0PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5BZHVsdDwva2V5 d29yZD48a2V5d29yZD5BbnRpdmlyYWwgQWdlbnRzL3RoZXJhcGV1dGljIHVzZTwva2V5d29yZD48 a2V5d29yZD5CZXRhY29yb25hdmlydXMvKmlzb2xhdGlvbiAmYW1wOyBwdXJpZmljYXRpb248L2tl eXdvcmQ+PGtleXdvcmQ+QmlsaXJ1YmluL2Jsb29kPC9rZXl3b3JkPjxrZXl3b3JkPkJsb29kIENo ZW1pY2FsIEFuYWx5c2lzPC9rZXl3b3JkPjxrZXl3b3JkPkNoaW5hL2VwaWRlbWlvbG9neTwva2V5 d29yZD48a2V5d29yZD5Db3JvbmF2aXJ1cyBJbmZlY3Rpb25zLypjb21wbGljYXRpb25zLypwYXRo b2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+RW56eW1lcy9ibG9vZDwva2V5d29yZD48a2V5d29yZD5G ZW1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+SG9zcGl0YWxzPC9rZXl3b3JkPjxrZXl3b3JkPkh1bWFu czwva2V5d29yZD48a2V5d29yZD5MaXZlciBEaXNlYXNlcy9kcnVnIHRoZXJhcHkvKmVwaWRlbWlv bG9neS8qZXRpb2xvZ3k8L2tleXdvcmQ+PGtleXdvcmQ+KkxpdmVyIEZ1bmN0aW9uIFRlc3RzPC9r ZXl3b3JkPjxrZXl3b3JkPkxvcGluYXZpci90aGVyYXBldXRpYyB1c2U8L2tleXdvcmQ+PGtleXdv cmQ+TWFsZTwva2V5d29yZD48a2V5d29yZD5NaWRkbGUgQWdlZDwva2V5d29yZD48a2V5d29yZD5Q YW5kZW1pY3M8L2tleXdvcmQ+PGtleXdvcmQ+UG5ldW1vbmlhLCBWaXJhbC8qY29tcGxpY2F0aW9u cy8qcGF0aG9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPlByZXZhbGVuY2U8L2tleXdvcmQ+PGtleXdv cmQ+UmV0cm9zcGVjdGl2ZSBTdHVkaWVzPC9rZXl3b3JkPjxrZXl3b3JkPlJpdG9uYXZpci90aGVy YXBldXRpYyB1c2U8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48 cHViLWRhdGVzPjxkYXRlPkp1bjwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxpc2JuPjE1NDIt MzU2NSAoUHJpbnQpJiN4RDsxNTQyLTM1NjU8L2lzYm4+PGFjY2Vzc2lvbi1udW0+MzIyODMzMjU8 L2FjY2Vzc2lvbi1udW0+PHVybHM+PC91cmxzPjxjdXN0b20yPlBtYzcxOTQ4NjU8L2N1c3RvbTI+ PGVsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjEwLjEwMTYvai5jZ2guMjAyMC4wNC4wMDI8L2VsZWN0 cm9uaWMtcmVzb3VyY2UtbnVtPjxyZW1vdGUtZGF0YWJhc2UtcHJvdmlkZXI+TmxtPC9yZW1vdGUt ZGF0YWJhc2UtcHJvdmlkZXI+PGxhbmd1YWdlPmVuZzwvbGFuZ3VhZ2U+PC9yZWNvcmQ+PC9DaXRl PjwvRW5kTm90ZT5= ADDIN EN.CITE.DATA (15). در زمینه سارس کووید2، عنوان شده ‌است که ترکیبی از عفونت ویروسی و تهویه مکانیکی منجر به آسیب اندوتلیال می‌شود که منجر به فعالشدن پلاکت، تجمع و ترومبوز در ریه و مصرف بیش‌از حد پلاکت می‌شود ADDIN EN.CITE <EndNote><Cite><Author>Yang</Author><Year>2005</Year><RecNum>82</RecNum><DisplayText>(36)</DisplayText><record><rec-number>82</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">82</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Yang, Mo</author><author>Ng, Margaret H. L.</author><author>Li, Chi Kong</author></authors></contributors><titles><title>Thrombocytopenia in patients with severe acute respiratory syndrome (review)</title><secondary-title>Hematology</secondary-title></titles><periodical><full-title>Hematology</full-title></periodical><pages>101-105</pages><volume>10</volume><number>2</number><dates><year>2005</year><pub-dates><date>2005/04/01</date></pub-dates></dates><publisher>Taylor & Francis</publisher><isbn>null</isbn><urls><related-urls><url>https://doi.org/10.1080/10245330400026170</url></related-urls></urls><electronic-resource-num>10.1080/10245330400026170</electronic-resource-num></record></Cite></EndNote>(36). با وجود اینکه در مطالعات کاهش تعداد پلاکتها با افزایش مرگ در مبتلایان به کووید-19 در ارتباط بوده‌ است PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5CaTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051 bT41NDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMzcsIDM4KTwvRGlzcGxheVRleHQ+PHJlY29yZD48 cmVjLW51bWJlcj41NDwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGIt aWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTQ8L2tleT48L2ZvcmVp Z24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNv bnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPkJpLCBYaWFvamllPC9hdXRob3I+PGF1dGhvcj5T dSwgWmhlbmd4aWFuPC9hdXRob3I+PGF1dGhvcj5ZYW4sIEhhaXhpPC9hdXRob3I+PGF1dGhvcj5E dSwgSnVwaW5nPC9hdXRob3I+PGF1dGhvcj5XYW5nLCBKaW5nPC9hdXRob3I+PGF1dGhvcj5DaGVu LCBMaW5waW5nPC9hdXRob3I+PGF1dGhvcj5QZW5nLCBNaW5mZWk8L2F1dGhvcj48YXV0aG9yPkNo ZW4sIFNoaXlvbmc8L2F1dGhvcj48YXV0aG9yPlNoZW4sIEJvPC9hdXRob3I+PGF1dGhvcj5MaSwg SnVuPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlByZWRp Y3Rpb24gb2Ygc2V2ZXJlIGlsbG5lc3MgZHVlIHRvIENPVklELTE5IGJhc2VkIG9uIGFuIGFuYWx5 c2lzIG9mIGluaXRpYWwgRmlicmlub2dlbiB0byBBbGJ1bWluIFJhdGlvIGFuZCBQbGF0ZWxldCBj b3VudDwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5QbGF0ZWxldHM8L3NlY29uZGFyeS10aXRsZT48 YWx0LXRpdGxlPlBsYXRlbGV0czwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxs LXRpdGxlPlBsYXRlbGV0czwvZnVsbC10aXRsZT48YWJici0xPlBsYXRlbGV0czwvYWJici0xPjwv cGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+UGxhdGVsZXRzPC9mdWxsLXRp dGxlPjxhYmJyLTE+UGxhdGVsZXRzPC9hYmJyLTE+PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+Njc0 LTY3OTwvcGFnZXM+PHZvbHVtZT4zMTwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxlZGl0aW9u PjA1LzA1PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5DT1ZJRC0xOTwva2V5d29yZD48a2V5 d29yZD5Db2FndWxhdGlvbiBhbmQgRmlicmlub2x5c2lzPC9rZXl3b3JkPjxrZXl3b3JkPmZpYnJp bm9nZW4tdG8tQWxidW1pbiBSYXRpbyAoRkFSKTwva2V5d29yZD48a2V5d29yZD5ub24tU2V2ZXJl IFN1cnZpdmFsIChOU1MpPC9rZXl3b3JkPjxrZXl3b3JkPnBsYXRlbGV0IGNvdW50IChQTFQpPC9r ZXl3b3JkPjxrZXl3b3JkPnByZWRpY3Rpb248L2tleXdvcmQ+PGtleXdvcmQ+QWR1bHQ8L2tleXdv cmQ+PGtleXdvcmQ+QXJlYSBVbmRlciBDdXJ2ZTwva2V5d29yZD48a2V5d29yZD4qQmV0YWNvcm9u YXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPkJpb21hcmtlcnMvYmxvb2Q8L2tleXdvcmQ+PGtleXdv cmQ+Qmxvb2QgQ29hZ3VsYXRpb24gVGVzdHM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmEvZXBpZGVt aW9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvKmJsb29kL2Vw aWRlbWlvbG9neTwva2V5d29yZD48a2V5d29yZD5EaXNlYXNlIFByb2dyZXNzaW9uPC9rZXl3b3Jk PjxrZXl3b3JkPkZlbWFsZTwva2V5d29yZD48a2V5d29yZD5GaWJyaW4gRmlicmlub2dlbiBEZWdy YWRhdGlvbiBQcm9kdWN0cy9hbmFseXNpczwva2V5d29yZD48a2V5d29yZD5GaWJyaW5vZ2VuLyph bmFseXNpczwva2V5d29yZD48a2V5d29yZD5IdW1hbnM8L2tleXdvcmQ+PGtleXdvcmQ+S2FwbGFu LU1laWVyIEVzdGltYXRlPC9rZXl3b3JkPjxrZXl3b3JkPk1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+ TWlkZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+Kk5vbW9ncmFtczwva2V5d29yZD48a2V5d29y ZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxrZXl3b3JkPipQbGF0ZWxldCBDb3VudDwva2V5d29yZD48 a2V5d29yZD5QbmV1bW9uaWEsIFZpcmFsLypibG9vZC9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtl eXdvcmQ+UHJlZGljdGl2ZSBWYWx1ZSBvZiBUZXN0czwva2V5d29yZD48a2V5d29yZD5Qcm9nbm9z aXM8L2tleXdvcmQ+PGtleXdvcmQ+UHJvcG9ydGlvbmFsIEhhemFyZHMgTW9kZWxzPC9rZXl3b3Jk PjxrZXl3b3JkPlJPQyBDdXJ2ZTwva2V5d29yZD48a2V5d29yZD5SZXRyb3NwZWN0aXZlIFN0dWRp ZXM8L2tleXdvcmQ+PGtleXdvcmQ+UmlzayBGYWN0b3JzPC9rZXl3b3JkPjxrZXl3b3JkPlNlcnVt IEFsYnVtaW4sIEh1bWFuLyphbmFseXNpczwva2V5d29yZD48a2V5d29yZD5TeW1wdG9tIEFzc2Vz c21lbnQ8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVz PjxwdWJsaXNoZXI+VGF5bG9yICZhbXA7IEZyYW5jaXM8L3B1Ymxpc2hlcj48aXNibj4xMzY5LTE2 MzUmI3hEOzA5NTMtNzEwNDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjM2Nzc2NTwvYWNjZXNzaW9u LW51bT48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9wdWJtZWQubmNiaS5ubG0ubmlo Lmdvdi8zMjM2Nzc2NTwvdXJsPjx1cmw+aHR0cHM6Ly93d3cubmNiaS5ubG0ubmloLmdvdi9wbWMv YXJ0aWNsZXMvUE1DNzIxMjU0My88L3VybD48L3JlbGF0ZWQtdXJscz48L3VybHM+PGVsZWN0cm9u aWMtcmVzb3VyY2UtbnVtPjEwLjEwODAvMDk1MzcxMDQuMjAyMC4xNzYwMjMwPC9lbGVjdHJvbmlj LXJlc291cmNlLW51bT48cmVtb3RlLWRhdGFiYXNlLW5hbWU+UHViTWVkPC9yZW1vdGUtZGF0YWJh c2UtbmFtZT48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PENpdGU+PEF1 dGhvcj5aaGFuZzwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051bT44MzwvUmVjTnVtPjxy ZWNvcmQ+PHJlYy1udW1iZXI+ODM8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0i RU4iIGRiLWlkPSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjgzPC9rZXk+ PC9mb3JlaWduLWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10 eXBlPjxjb250cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaGFuZywgSmluLWppbjwvYXV0aG9y PjxhdXRob3I+Q2FvLCBZaS15dWFuPC9hdXRob3I+PGF1dGhvcj5UYW4sIEdlPC9hdXRob3I+PGF1 dGhvcj5Eb25nLCBYaWFuZzwvYXV0aG9yPjxhdXRob3I+V2FuZywgQmluLWNoZW48L2F1dGhvcj48 YXV0aG9yPkxpbiwgSnVuPC9hdXRob3I+PGF1dGhvcj5ZYW4sIFlvdS1xaW48L2F1dGhvcj48YXV0 aG9yPkxpdSwgR3VhbmctaHVpPC9hdXRob3I+PGF1dGhvcj5Ba2RpcywgTcO8YmVjY2VsPC9hdXRo b3I+PGF1dGhvcj5Ba2RpcywgQ2V6bWkgQS48L2F1dGhvcj48YXV0aG9yPkdhbywgWWEtZG9uZzwv YXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48dGl0bGVzPjx0aXRsZT5DbGluaWNhbCwg cmFkaW9sb2dpY2FsLCBhbmQgbGFib3JhdG9yeSBjaGFyYWN0ZXJpc3RpY3MgYW5kIHJpc2sgZmFj dG9ycyBmb3Igc2V2ZXJpdHkgYW5kIG1vcnRhbGl0eSBvZiAyODkgaG9zcGl0YWxpemVkIENPVklE LTE5IHBhdGllbnRzPC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPkFsbGVyZ3k8L3NlY29uZGFyeS10 aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5BbGxlcmd5PC9mdWxsLXRpdGxl PjwvcGVyaW9kaWNhbD48dm9sdW1lPm4vYTwvdm9sdW1lPjxudW1iZXI+bi9hPC9udW1iZXI+PGtl eXdvcmRzPjxrZXl3b3JkPmNsaW5pY2FsIGNoYXJhY3RlcmlzdGljczwva2V5d29yZD48a2V5d29y ZD5jb3JvbmF2aXJ1cyBkaXNlYXNlIDIwMTk8L2tleXdvcmQ+PGtleXdvcmQ+bW9ydGFsaXR5PC9r ZXl3b3JkPjxrZXl3b3JkPnJpc2sgZmFjdG9yczwva2V5d29yZD48a2V5d29yZD5zZXZlcml0eTwv a2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRh dGU+MjAyMC8wNy8xNDwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBX aWxleSAmYW1wOyBTb25zLCBMdGQ8L3B1Ymxpc2hlcj48aXNibj4wMTA1LTQ1Mzg8L2lzYm4+PHdv cmstdHlwZT5odHRwczovL2RvaS5vcmcvMTAuMTExMS9hbGwuMTQ0OTY8L3dvcmstdHlwZT48dXJs cz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2kub3JnLzEwLjExMTEvYWxsLjE0NDk2PC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT5odHRwczov L2RvaS5vcmcvMTAuMTExMS9hbGwuMTQ0OTY8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxhY2Nl c3MtZGF0ZT4yMDIwLzExLzIzPC9hY2Nlc3MtZGF0ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3Rl Pn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5CaTwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051 bT41NDwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oMzcsIDM4KTwvRGlzcGxheVRleHQ+PHJlY29yZD48 cmVjLW51bWJlcj41NDwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJFTiIgZGIt aWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0eGRlZCI+NTQ8L2tleT48L2ZvcmVp Z24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xlIj4xNzwvcmVmLXR5cGU+PGNv bnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPkJpLCBYaWFvamllPC9hdXRob3I+PGF1dGhvcj5T dSwgWmhlbmd4aWFuPC9hdXRob3I+PGF1dGhvcj5ZYW4sIEhhaXhpPC9hdXRob3I+PGF1dGhvcj5E dSwgSnVwaW5nPC9hdXRob3I+PGF1dGhvcj5XYW5nLCBKaW5nPC9hdXRob3I+PGF1dGhvcj5DaGVu LCBMaW5waW5nPC9hdXRob3I+PGF1dGhvcj5QZW5nLCBNaW5mZWk8L2F1dGhvcj48YXV0aG9yPkNo ZW4sIFNoaXlvbmc8L2F1dGhvcj48YXV0aG9yPlNoZW4sIEJvPC9hdXRob3I+PGF1dGhvcj5MaSwg SnVuPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPlByZWRp Y3Rpb24gb2Ygc2V2ZXJlIGlsbG5lc3MgZHVlIHRvIENPVklELTE5IGJhc2VkIG9uIGFuIGFuYWx5 c2lzIG9mIGluaXRpYWwgRmlicmlub2dlbiB0byBBbGJ1bWluIFJhdGlvIGFuZCBQbGF0ZWxldCBj b3VudDwvdGl0bGU+PHNlY29uZGFyeS10aXRsZT5QbGF0ZWxldHM8L3NlY29uZGFyeS10aXRsZT48 YWx0LXRpdGxlPlBsYXRlbGV0czwvYWx0LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxs LXRpdGxlPlBsYXRlbGV0czwvZnVsbC10aXRsZT48YWJici0xPlBsYXRlbGV0czwvYWJici0xPjwv cGVyaW9kaWNhbD48YWx0LXBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+UGxhdGVsZXRzPC9mdWxsLXRp dGxlPjxhYmJyLTE+UGxhdGVsZXRzPC9hYmJyLTE+PC9hbHQtcGVyaW9kaWNhbD48cGFnZXM+Njc0 LTY3OTwvcGFnZXM+PHZvbHVtZT4zMTwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxlZGl0aW9u PjA1LzA1PC9lZGl0aW9uPjxrZXl3b3Jkcz48a2V5d29yZD5DT1ZJRC0xOTwva2V5d29yZD48a2V5 d29yZD5Db2FndWxhdGlvbiBhbmQgRmlicmlub2x5c2lzPC9rZXl3b3JkPjxrZXl3b3JkPmZpYnJp bm9nZW4tdG8tQWxidW1pbiBSYXRpbyAoRkFSKTwva2V5d29yZD48a2V5d29yZD5ub24tU2V2ZXJl IFN1cnZpdmFsIChOU1MpPC9rZXl3b3JkPjxrZXl3b3JkPnBsYXRlbGV0IGNvdW50IChQTFQpPC9r ZXl3b3JkPjxrZXl3b3JkPnByZWRpY3Rpb248L2tleXdvcmQ+PGtleXdvcmQ+QWR1bHQ8L2tleXdv cmQ+PGtleXdvcmQ+QXJlYSBVbmRlciBDdXJ2ZTwva2V5d29yZD48a2V5d29yZD4qQmV0YWNvcm9u YXZpcnVzPC9rZXl3b3JkPjxrZXl3b3JkPkJpb21hcmtlcnMvYmxvb2Q8L2tleXdvcmQ+PGtleXdv cmQ+Qmxvb2QgQ29hZ3VsYXRpb24gVGVzdHM8L2tleXdvcmQ+PGtleXdvcmQ+Q2hpbmEvZXBpZGVt aW9sb2d5PC9rZXl3b3JkPjxrZXl3b3JkPkNvcm9uYXZpcnVzIEluZmVjdGlvbnMvKmJsb29kL2Vw aWRlbWlvbG9neTwva2V5d29yZD48a2V5d29yZD5EaXNlYXNlIFByb2dyZXNzaW9uPC9rZXl3b3Jk PjxrZXl3b3JkPkZlbWFsZTwva2V5d29yZD48a2V5d29yZD5GaWJyaW4gRmlicmlub2dlbiBEZWdy YWRhdGlvbiBQcm9kdWN0cy9hbmFseXNpczwva2V5d29yZD48a2V5d29yZD5GaWJyaW5vZ2VuLyph bmFseXNpczwva2V5d29yZD48a2V5d29yZD5IdW1hbnM8L2tleXdvcmQ+PGtleXdvcmQ+S2FwbGFu LU1laWVyIEVzdGltYXRlPC9rZXl3b3JkPjxrZXl3b3JkPk1hbGU8L2tleXdvcmQ+PGtleXdvcmQ+ TWlkZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+Kk5vbW9ncmFtczwva2V5d29yZD48a2V5d29y ZD4qUGFuZGVtaWNzPC9rZXl3b3JkPjxrZXl3b3JkPipQbGF0ZWxldCBDb3VudDwva2V5d29yZD48 a2V5d29yZD5QbmV1bW9uaWEsIFZpcmFsLypibG9vZC9lcGlkZW1pb2xvZ3k8L2tleXdvcmQ+PGtl eXdvcmQ+UHJlZGljdGl2ZSBWYWx1ZSBvZiBUZXN0czwva2V5d29yZD48a2V5d29yZD5Qcm9nbm9z aXM8L2tleXdvcmQ+PGtleXdvcmQ+UHJvcG9ydGlvbmFsIEhhemFyZHMgTW9kZWxzPC9rZXl3b3Jk PjxrZXl3b3JkPlJPQyBDdXJ2ZTwva2V5d29yZD48a2V5d29yZD5SZXRyb3NwZWN0aXZlIFN0dWRp ZXM8L2tleXdvcmQ+PGtleXdvcmQ+UmlzayBGYWN0b3JzPC9rZXl3b3JkPjxrZXl3b3JkPlNlcnVt IEFsYnVtaW4sIEh1bWFuLyphbmFseXNpczwva2V5d29yZD48a2V5d29yZD5TeW1wdG9tIEFzc2Vz c21lbnQ8L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAyMDwveWVhcj48L2RhdGVz PjxwdWJsaXNoZXI+VGF5bG9yICZhbXA7IEZyYW5jaXM8L3B1Ymxpc2hlcj48aXNibj4xMzY5LTE2 MzUmI3hEOzA5NTMtNzEwNDwvaXNibj48YWNjZXNzaW9uLW51bT4zMjM2Nzc2NTwvYWNjZXNzaW9u LW51bT48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9wdWJtZWQubmNiaS5ubG0ubmlo Lmdvdi8zMjM2Nzc2NTwvdXJsPjx1cmw+aHR0cHM6Ly93d3cubmNiaS5ubG0ubmloLmdvdi9wbWMv YXJ0aWNsZXMvUE1DNzIxMjU0My88L3VybD48L3JlbGF0ZWQtdXJscz48L3VybHM+PGVsZWN0cm9u aWMtcmVzb3VyY2UtbnVtPjEwLjEwODAvMDk1MzcxMDQuMjAyMC4xNzYwMjMwPC9lbGVjdHJvbmlj LXJlc291cmNlLW51bT48cmVtb3RlLWRhdGFiYXNlLW5hbWU+UHViTWVkPC9yZW1vdGUtZGF0YWJh c2UtbmFtZT48bGFuZ3VhZ2U+ZW5nPC9sYW5ndWFnZT48L3JlY29yZD48L0NpdGU+PENpdGU+PEF1 dGhvcj5aaGFuZzwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+PFJlY051bT44MzwvUmVjTnVtPjxy ZWNvcmQ+PHJlYy1udW1iZXI+ODM8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0i RU4iIGRiLWlkPSI5cjIyMHhzOTZwZTJ2cGVmdDIxcDB0dDUwNXZwdjIydHhkZWQiPjgzPC9rZXk+ PC9mb3JlaWduLWtleXM+PHJlZi10eXBlIG5hbWU9IkpvdXJuYWwgQXJ0aWNsZSI+MTc8L3JlZi10 eXBlPjxjb250cmlidXRvcnM+PGF1dGhvcnM+PGF1dGhvcj5aaGFuZywgSmluLWppbjwvYXV0aG9y PjxhdXRob3I+Q2FvLCBZaS15dWFuPC9hdXRob3I+PGF1dGhvcj5UYW4sIEdlPC9hdXRob3I+PGF1 dGhvcj5Eb25nLCBYaWFuZzwvYXV0aG9yPjxhdXRob3I+V2FuZywgQmluLWNoZW48L2F1dGhvcj48 YXV0aG9yPkxpbiwgSnVuPC9hdXRob3I+PGF1dGhvcj5ZYW4sIFlvdS1xaW48L2F1dGhvcj48YXV0 aG9yPkxpdSwgR3VhbmctaHVpPC9hdXRob3I+PGF1dGhvcj5Ba2RpcywgTcO8YmVjY2VsPC9hdXRo b3I+PGF1dGhvcj5Ba2RpcywgQ2V6bWkgQS48L2F1dGhvcj48YXV0aG9yPkdhbywgWWEtZG9uZzwv YXV0aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48dGl0bGVzPjx0aXRsZT5DbGluaWNhbCwg cmFkaW9sb2dpY2FsLCBhbmQgbGFib3JhdG9yeSBjaGFyYWN0ZXJpc3RpY3MgYW5kIHJpc2sgZmFj dG9ycyBmb3Igc2V2ZXJpdHkgYW5kIG1vcnRhbGl0eSBvZiAyODkgaG9zcGl0YWxpemVkIENPVklE LTE5IHBhdGllbnRzPC90aXRsZT48c2Vjb25kYXJ5LXRpdGxlPkFsbGVyZ3k8L3NlY29uZGFyeS10 aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5BbGxlcmd5PC9mdWxsLXRpdGxl PjwvcGVyaW9kaWNhbD48dm9sdW1lPm4vYTwvdm9sdW1lPjxudW1iZXI+bi9hPC9udW1iZXI+PGtl eXdvcmRzPjxrZXl3b3JkPmNsaW5pY2FsIGNoYXJhY3RlcmlzdGljczwva2V5d29yZD48a2V5d29y ZD5jb3JvbmF2aXJ1cyBkaXNlYXNlIDIwMTk8L2tleXdvcmQ+PGtleXdvcmQ+bW9ydGFsaXR5PC9r ZXl3b3JkPjxrZXl3b3JkPnJpc2sgZmFjdG9yczwva2V5d29yZD48a2V5d29yZD5zZXZlcml0eTwv a2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVhcj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRh dGU+MjAyMC8wNy8xNDwvZGF0ZT48L3B1Yi1kYXRlcz48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBX aWxleSAmYW1wOyBTb25zLCBMdGQ8L3B1Ymxpc2hlcj48aXNibj4wMTA1LTQ1Mzg8L2lzYm4+PHdv cmstdHlwZT5odHRwczovL2RvaS5vcmcvMTAuMTExMS9hbGwuMTQ0OTY8L3dvcmstdHlwZT48dXJs cz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2kub3JnLzEwLjExMTEvYWxsLjE0NDk2PC91 cmw+PC9yZWxhdGVkLXVybHM+PC91cmxzPjxlbGVjdHJvbmljLXJlc291cmNlLW51bT5odHRwczov L2RvaS5vcmcvMTAuMTExMS9hbGwuMTQ0OTY8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxhY2Nl c3MtZGF0ZT4yMDIwLzExLzIzPC9hY2Nlc3MtZGF0ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3Rl Pn== ADDIN EN.CITE.DATA (37, 10)؛ اما در مطالعه‌ی حاضر، اگر چه متوسط میزان پلاکت در گروه متوفی نسبت به گروه بازمانده کمتر بود اما از لحاظ آماری تفاوت معناداری بین دو گروه وجود نداشت. در زمینه مقادیر الکترولیتی مقادیر پتاسیم پایه و در زمان ترخیص و فوت در محدوده طبیعی بود که این یافته با نتایج مطالعات دیگر همسو بود PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5BZ2dhcndhbDwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+ PFJlY051bT4xMzc8L1JlY051bT48RGlzcGxheVRleHQ+KDUsIDM0KTwvRGlzcGxheVRleHQ+PHJl Y29yZD48cmVjLW51bWJlcj4xMzc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0i RU4iIGRiLWlkPSI5c2U1djB2dHZ4cjJmaGUwenYxeDlzZm1ycjI5cmZ4dnI5ZHQiPjEzNzwva2V5 PjwvZm9yZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYt dHlwZT48Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+QWdnYXJ3YWwsIFNhdXJhYmg8L2F1 dGhvcj48YXV0aG9yPkdhcmNpYS1UZWxsZXMsIE5lbHNvbjwvYXV0aG9yPjxhdXRob3I+QWdnYXJ3 YWwsIEdhdXJhdjwvYXV0aG9yPjxhdXRob3I+TGF2aWUsIENhcmw8L2F1dGhvcj48YXV0aG9yPkxp cHBpLCBHaXVzZXBwZTwvYXV0aG9yPjxhdXRob3I+SGVucnksIEJyYW5kb24gTWljaGFlbDwvYXV0 aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48dGl0bGVzPjx0aXRsZT5DbGluaWNhbCBmZWF0 dXJlcywgbGFib3JhdG9yeSBjaGFyYWN0ZXJpc3RpY3MsIGFuZCBvdXRjb21lcyBvZiBwYXRpZW50 cyBob3NwaXRhbGl6ZWQgd2l0aCBjb3JvbmF2aXJ1cyBkaXNlYXNlIDIwMTkgKENPVklELTE5KTog RWFybHkgcmVwb3J0IGZyb20gdGhlIFVuaXRlZCBTdGF0ZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0 bGU+RGlhZ25vc2lzPC9zZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwt dGl0bGU+RGlhZ25vc2lzPC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+OTEtOTY8L3Bh Z2VzPjx2b2x1bWU+Nzwvdm9sdW1lPjxudW1iZXI+MjwvbnVtYmVyPjxkYXRlcz48eWVhcj4yMDIw PC95ZWFyPjwvZGF0ZXM+PGlzYm4+MjE5NC04MDExPC9pc2JuPjx1cmxzPjwvdXJscz48L3JlY29y ZD48L0NpdGU+PENpdGU+PEF1dGhvcj5XYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+MzwvUmVjTnVtPjxyZWNvcmQ+PHJlYy1udW1iZXI+MzwvcmVjLW51bWJlcj48Zm9yZWlnbi1r ZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0 eGRlZCI+Mzwva2V5PjwvZm9yZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGlj bGUiPjE3PC9yZWYtdHlwZT48Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+V2FuLCBTdXhp bjwvYXV0aG9yPjxhdXRob3I+WGlhbmcsIFlpPC9hdXRob3I+PGF1dGhvcj5GYW5nLCBXZWk8L2F1 dGhvcj48YXV0aG9yPlpoZW5nLCBZdTwvYXV0aG9yPjxhdXRob3I+TGksIEJvcXVuPC9hdXRob3I+ PGF1dGhvcj5IdSwgWWFuanVuPC9hdXRob3I+PGF1dGhvcj5MYW5nLCBDaHVuaHVpPC9hdXRob3I+ PGF1dGhvcj5IdWFuZywgRGFvcWl1PC9hdXRob3I+PGF1dGhvcj5TdW4sIFFpdXlhbjwvYXV0aG9y PjxhdXRob3I+WGlvbmcsIFlhbjwvYXV0aG9yPjxhdXRob3I+SHVhbmcsIFhpYTwvYXV0aG9yPjxh dXRob3I+THYsIEppbmdsb25nPC9hdXRob3I+PGF1dGhvcj5MdW8sIFlhbGluZzwvYXV0aG9yPjxh dXRob3I+U2hlbiwgTGk8L2F1dGhvcj48YXV0aG9yPllhbmcsIEhhb3JhbjwvYXV0aG9yPjxhdXRo b3I+SHVhbmcsIEd1PC9hdXRob3I+PGF1dGhvcj5ZYW5nLCBSdWlzaGFuPC9hdXRob3I+PC9hdXRo b3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2FsIGZlYXR1cmVzIGFuZCB0 cmVhdG1lbnQgb2YgQ09WSUQtMTkgcGF0aWVudHMgaW4gbm9ydGhlYXN0IENob25ncWluZzwvdGl0 bGU+PHNlY29uZGFyeS10aXRsZT5Kb3VybmFsIG9mIE1lZGljYWwgVmlyb2xvZ3k8L3NlY29uZGFy eS10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5Kb3VybmFsIG9mIE1lZGlj YWwgVmlyb2xvZ3k8L2Z1bGwtdGl0bGU+PC9wZXJpb2RpY2FsPjxwYWdlcz43OTctODA2PC9wYWdl cz48dm9sdW1lPjkyPC92b2x1bWU+PG51bWJlcj43PC9udW1iZXI+PGtleXdvcmRzPjxrZXl3b3Jk PmNsaW5pY2FsIGZlYXR1cmVzPC9rZXl3b3JkPjxrZXl3b3JkPmNvZ25pdGlvbjwva2V5d29yZD48 a2V5d29yZD5DT1ZJRC0xOTwva2V5d29yZD48a2V5d29yZD5ub3J0aGVhc3QgQ2hvbmdxaW5nPC9r ZXl3b3JkPjxrZXl3b3JkPnRyZWF0bWVudDwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVh cj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+MjAyMC8wNy8wMTwvZGF0ZT48L3B1Yi1kYXRl cz48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSAmYW1wOyBTb25zLCBMdGQ8L3B1Ymxpc2hl cj48aXNibj4wMTQ2LTY2MTU8L2lzYm4+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJsPmh0dHBzOi8v ZG9pLm9yZy8xMC4xMDAyL2ptdi4yNTc4MzwvdXJsPjwvcmVsYXRlZC11cmxzPjwvdXJscz48ZWxl Y3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAwMi9qbXYuMjU3ODM8L2VsZWN0cm9uaWMtcmVzb3Vy Y2UtbnVtPjxhY2Nlc3MtZGF0ZT4yMDIwLzA5LzAyPC9hY2Nlc3MtZGF0ZT48L3JlY29yZD48L0Np dGU+PC9FbmROb3RlPn== ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5BZ2dhcndhbDwvQXV0aG9yPjxZZWFyPjIwMjA8L1llYXI+ PFJlY051bT4xMzc8L1JlY051bT48RGlzcGxheVRleHQ+KDUsIDM0KTwvRGlzcGxheVRleHQ+PHJl Y29yZD48cmVjLW51bWJlcj4xMzc8L3JlYy1udW1iZXI+PGZvcmVpZ24ta2V5cz48a2V5IGFwcD0i RU4iIGRiLWlkPSI5c2U1djB2dHZ4cjJmaGUwenYxeDlzZm1ycjI5cmZ4dnI5ZHQiPjEzNzwva2V5 PjwvZm9yZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYt dHlwZT48Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+QWdnYXJ3YWwsIFNhdXJhYmg8L2F1 dGhvcj48YXV0aG9yPkdhcmNpYS1UZWxsZXMsIE5lbHNvbjwvYXV0aG9yPjxhdXRob3I+QWdnYXJ3 YWwsIEdhdXJhdjwvYXV0aG9yPjxhdXRob3I+TGF2aWUsIENhcmw8L2F1dGhvcj48YXV0aG9yPkxp cHBpLCBHaXVzZXBwZTwvYXV0aG9yPjxhdXRob3I+SGVucnksIEJyYW5kb24gTWljaGFlbDwvYXV0 aG9yPjwvYXV0aG9ycz48L2NvbnRyaWJ1dG9ycz48dGl0bGVzPjx0aXRsZT5DbGluaWNhbCBmZWF0 dXJlcywgbGFib3JhdG9yeSBjaGFyYWN0ZXJpc3RpY3MsIGFuZCBvdXRjb21lcyBvZiBwYXRpZW50 cyBob3NwaXRhbGl6ZWQgd2l0aCBjb3JvbmF2aXJ1cyBkaXNlYXNlIDIwMTkgKENPVklELTE5KTog RWFybHkgcmVwb3J0IGZyb20gdGhlIFVuaXRlZCBTdGF0ZXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0 bGU+RGlhZ25vc2lzPC9zZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwt dGl0bGU+RGlhZ25vc2lzPC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+OTEtOTY8L3Bh Z2VzPjx2b2x1bWU+Nzwvdm9sdW1lPjxudW1iZXI+MjwvbnVtYmVyPjxkYXRlcz48eWVhcj4yMDIw PC95ZWFyPjwvZGF0ZXM+PGlzYm4+MjE5NC04MDExPC9pc2JuPjx1cmxzPjwvdXJscz48L3JlY29y ZD48L0NpdGU+PENpdGU+PEF1dGhvcj5XYW48L0F1dGhvcj48WWVhcj4yMDIwPC9ZZWFyPjxSZWNO dW0+MzwvUmVjTnVtPjxyZWNvcmQ+PHJlYy1udW1iZXI+MzwvcmVjLW51bWJlcj48Zm9yZWlnbi1r ZXlzPjxrZXkgYXBwPSJFTiIgZGItaWQ9IjlyMjIweHM5NnBlMnZwZWZ0MjFwMHR0NTA1dnB2MjJ0 eGRlZCI+Mzwva2V5PjwvZm9yZWlnbi1rZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGlj bGUiPjE3PC9yZWYtdHlwZT48Y29udHJpYnV0b3JzPjxhdXRob3JzPjxhdXRob3I+V2FuLCBTdXhp bjwvYXV0aG9yPjxhdXRob3I+WGlhbmcsIFlpPC9hdXRob3I+PGF1dGhvcj5GYW5nLCBXZWk8L2F1 dGhvcj48YXV0aG9yPlpoZW5nLCBZdTwvYXV0aG9yPjxhdXRob3I+TGksIEJvcXVuPC9hdXRob3I+ PGF1dGhvcj5IdSwgWWFuanVuPC9hdXRob3I+PGF1dGhvcj5MYW5nLCBDaHVuaHVpPC9hdXRob3I+ PGF1dGhvcj5IdWFuZywgRGFvcWl1PC9hdXRob3I+PGF1dGhvcj5TdW4sIFFpdXlhbjwvYXV0aG9y PjxhdXRob3I+WGlvbmcsIFlhbjwvYXV0aG9yPjxhdXRob3I+SHVhbmcsIFhpYTwvYXV0aG9yPjxh dXRob3I+THYsIEppbmdsb25nPC9hdXRob3I+PGF1dGhvcj5MdW8sIFlhbGluZzwvYXV0aG9yPjxh dXRob3I+U2hlbiwgTGk8L2F1dGhvcj48YXV0aG9yPllhbmcsIEhhb3JhbjwvYXV0aG9yPjxhdXRo b3I+SHVhbmcsIEd1PC9hdXRob3I+PGF1dGhvcj5ZYW5nLCBSdWlzaGFuPC9hdXRob3I+PC9hdXRo b3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkNsaW5pY2FsIGZlYXR1cmVzIGFuZCB0 cmVhdG1lbnQgb2YgQ09WSUQtMTkgcGF0aWVudHMgaW4gbm9ydGhlYXN0IENob25ncWluZzwvdGl0 bGU+PHNlY29uZGFyeS10aXRsZT5Kb3VybmFsIG9mIE1lZGljYWwgVmlyb2xvZ3k8L3NlY29uZGFy eS10aXRsZT48L3RpdGxlcz48cGVyaW9kaWNhbD48ZnVsbC10aXRsZT5Kb3VybmFsIG9mIE1lZGlj YWwgVmlyb2xvZ3k8L2Z1bGwtdGl0bGU+PC9wZXJpb2RpY2FsPjxwYWdlcz43OTctODA2PC9wYWdl cz48dm9sdW1lPjkyPC92b2x1bWU+PG51bWJlcj43PC9udW1iZXI+PGtleXdvcmRzPjxrZXl3b3Jk PmNsaW5pY2FsIGZlYXR1cmVzPC9rZXl3b3JkPjxrZXl3b3JkPmNvZ25pdGlvbjwva2V5d29yZD48 a2V5d29yZD5DT1ZJRC0xOTwva2V5d29yZD48a2V5d29yZD5ub3J0aGVhc3QgQ2hvbmdxaW5nPC9r ZXl3b3JkPjxrZXl3b3JkPnRyZWF0bWVudDwva2V5d29yZD48L2tleXdvcmRzPjxkYXRlcz48eWVh cj4yMDIwPC95ZWFyPjxwdWItZGF0ZXM+PGRhdGU+MjAyMC8wNy8wMTwvZGF0ZT48L3B1Yi1kYXRl cz48L2RhdGVzPjxwdWJsaXNoZXI+Sm9obiBXaWxleSAmYW1wOyBTb25zLCBMdGQ8L3B1Ymxpc2hl cj48aXNibj4wMTQ2LTY2MTU8L2lzYm4+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJsPmh0dHBzOi8v ZG9pLm9yZy8xMC4xMDAyL2ptdi4yNTc4MzwvdXJsPjwvcmVsYXRlZC11cmxzPjwvdXJscz48ZWxl Y3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAwMi9qbXYuMjU3ODM8L2VsZWN0cm9uaWMtcmVzb3Vy Y2UtbnVtPjxhY2Nlc3MtZGF0ZT4yMDIwLzA5LzAyPC9hY2Nlc3MtZGF0ZT48L3JlY29yZD48L0Np dGU+PC9FbmROb3RlPn== ADDIN EN.CITE.DATA (5, 34).در مطالعهی حاضر متوسط میزان سدیم در بیماران فوت شده نسبت به گروه بازمانده کاهش یافت و از این نظر تفاوت معناداری بین دو گروه وجود داشت که با یافتههای وانگ و همکاران همسو بود ADDIN EN.CITE <EndNote><Cite><Author>Wan</Author><Year>2020</Year><RecNum>3</RecNum><DisplayText>(34)</DisplayText><record><rec-number>3</rec-number><foreign-keys><key app="EN" db-id="9r220xs96pe2vpeft21p0tt505vpv22txded">3</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Wan, Suxin</author><author>Xiang, Yi</author><author>Fang, Wei</author><author>Zheng, Yu</author><author>Li, Boqun</author><author>Hu, Yanjun</author><author>Lang, Chunhui</author><author>Huang, Daoqiu</author><author>Sun, Qiuyan</author><author>Xiong, Yan</author><author>Huang, Xia</author><author>Lv, Jinglong</author><author>Luo, Yaling</author><author>Shen, Li</author><author>Yang, Haoran</author><author>Huang, Gu</author><author>Yang, Ruishan</author></authors></contributors><titles><title>Clinical features and treatment of COVID-19 patients in northeast Chongqing</title><secondary-title>Journal of Medical Virology</secondary-title></titles><periodical><full-title>Journal of Medical Virology</full-title></periodical><pages>797-806</pages><volume>92</volume><number>7</number><keywords><keyword>clinical features</keyword><keyword>cognition</keyword><keyword>COVID-19</keyword><keyword>northeast Chongqing</keyword><keyword>treatment</keyword></keywords><dates><year>2020</year><pub-dates><date>2020/07/01</date></pub-dates></dates><publisher>John Wiley & Sons, Ltd</publisher><isbn>0146-6615</isbn><urls><related-urls><url>https://doi.org/10.1002/jmv.25783</url></related-urls></urls><electronic-resource-num>10.1002/jmv.25783</electronic-resource-num><access-date>2020/09/02</access-date></record></Cite></EndNote>(34). در مطالعهی حاضر، شایع‌ترین یافته در سیتیاسکن ریه بیماران، انفیلتراسیون با الگوی گراندگلاس و کانسالیدیشن بود که وجود این ضایعات در گروه زنده مانده و فوت شده به لحاظ آماری تفاوت معناداری وجود داشت.

یافتههای رادیوگرافی در بیماران مبتلا به پنومونی بسته به زمان گذشته از شروع علائم، بسیار متغیر است. با اینحال، بیشترین یافتهها، انفیلتراسیون دو طرفه با الگوی گراندگلاس یا بینابینی، یا کدورتهای آلوئولار دوطرفه است که یافتههای ما نیز با این نتایج همسو بود ADDIN EN.CITE <EndNote><Cite><Author>Rivera-Izquierdo</Author><Year>2020</Year><RecNum>177</RecNum><DisplayText>(39)</DisplayText><record><rec-number>177</rec-number><foreign-keys><key app="EN" db-id="9se5v0vtvxr2fhe0zv1x9sfmrr29rfxvr9dt">177</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Rivera-Izquierdo, Mario</author><author>del Carmen Valero-Ubierna, Maria</author><author>R-delAmo, Juan Luis</author><author>Fernández-García, Miguel Ángel</author><author>Martínez-Diz, Silvia</author><author>Tahery-Mahmoud, Arezu</author><author>Rodríguez-Camacho, Marta</author><author>Gámiz-Molina, Ana Belén</author><author>Barba-Gyengo, Nicolás</author><author>Gámez-Baeza, Pablo</author></authors></contributors><titles><title>Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study</title><secondary-title>PloS one</secondary-title></titles><periodical><full-title>PloS one</full-title></periodical><pages>e0235107</pages><volume>15</volume><number>6</number><dates><year>2020</year></dates><isbn>1932-6203</isbn><urls></urls></record></Cite></EndNote>(33). در مطالعهی ما محدودیتهای مختلفی وجود داشت که ممکن است به طور بالقوه منجر به سوگیری شود. اول این که مطالعهی حاضر یک مطالعه گذشتهنگر و تک مرکز و نمونهای کوچک از بیماران بستری در بیمارستان بود. لذا دادههای استاندارد برای یک گروه بزرگتر برای ارزیابی پاسخ ایمنی در طول دوره عفونت با کووید-19 بهتر خواهد بود. دوم اینکه عفونت همزمان با عوامل میکروبی دیگر ممکن است بر نتایج پاسخ ایمنی در گروهی از بیماران مبتلا به کووید-19 تأثیر بگذارد. دیگر این که با توجه به گذشتهنگر بودن مطالعه امکان انجام برخی از آزمایشات نظیر تروپونین و دیدایمر وجود نداشت.

نت

یجه‌گیریعلائم تنفسی، سرفهی خشک، سردرد، لرز، یافتههای رادیولوژیک کانسالیدیشن علائم آزمایشگاهی کاهش لنفوسیت‌ها، همچنین در بین فاکتورهای دموگرافیک سن بالا و داشتن بیماریهای زمینهای تظاهرات شایع در این پژوهش بودند که به نظر می‌رسد باید بیشتر مورد توجه مراقبان سلامت حین ارزیابی بالینی مراجعان قرار گیرد.

حما

مال

حمایت مالی ندارد.

مشارکت نو

سندگانطراحی پژوهش: نویسنده اول و دوم. جمع‌آوری داده‌ها: نویسنده دوم و سوم. تجزیه و تحلیل داده‌ها: نویسنده اول و دوم. ثبت داده ها در نرم افزار: نویسنده سوم. تحلیل و تفسیر نتایج و تهیه گزارش و نوشتن پیش نویس اصلی: نویسنده اول. بررسی و ویرایش نوشته: نویسنده دوم و سوم. مصور سازی و نظارت: نویسنده اول و دوم و مدیریت پروژه و تامین بودجه: نویسنده دوم و سوم.همه‌ی نویسندگان نسخه‌ی منتشر شده‌ی مقاله را خوانده و با آن موافقت کردند.همه‌ی نویسندگان به‌طور یکسان در مفهوم‌سازی مقاله و نوشتن پیش‌نویس‌های اصلی و بعدی مشارکت داشته‌اند.

اعلام

هوش مصنوع

مولد و فناور

ی‌

ها

مبتن

بر هوش مصنوع

در فر

ای

ند

نگارشموردی وجود ندارد.

تعارض منافعهیچ یک از نویسندگان این مطالعه، افراد و یا دستگاهها تعارض منافعی برای انتشار این مقاله ندارند.

ملاحظات اخلاق

پیروی از اصول اخلاق پژوهشاین پژوهش کد اخلاق به شماره IR.QUMS.REC.1399.125 را از کمیته اخلاق دانشگاه قزوین دریافت کرده است. نویسندگان اصول اخلاقی را در انجام و انتشار این پژوهش علمی رعایت نموده‌اند و این موضوع مورد تأیید همه آن‌هاست.

بیانیه دسترسی به

داده‌هاداده‌های پژوهش حاضر از طریق درخواست از نویسندگان قابل دسترسی است.

تشکر

قدردان

که

فلاح

و همکاران

تظ

اهرات بال

و پاراکل

ماران

بستر

مبتلا به کوو

...

مراقبت

امروز

سال

هجدهم

شماره

140

4نویسندگان این مقاله مراتب تشکر و قدر دانی خود را از پرسنل بیمارستان ابراز می کنند.

References

ADDIN EN.REFLIST

1.Favaloro EJ, Lippi G. Recommendations for Minimal Laboratory Testing Panels in Patients with COVID-19: Potential for Prognostic Monitoring. Semin Thromb Hemost. 2020;41(03):379–82.

https://doi.org/

10.1055/s-0040-17094982.Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. The Lancet Respiratory medicine. 2020;8(4):420–2.

https://doi.org/

10.1016/S2213-2600(20)30076-X3.Shi H, Han X, Jiang N, Cao Y, Alwalid O, Gu J, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. The Lancet Infectious Diseases. 2020.

https://doi.org/

10.1016/S1473-3099(20)30086-44.Zu ZY, Jiang MD, Xu PP, Chen W, Ni QQ, Lu GM, et al. Coronavirus disease 2019 (COVID-19): a perspective from China. Radiology. 2020:200490.

https://doi.org/

10.1148/radiol.20202004905.Aggarwal S, Garcia-Telles N, Aggarwal G, Lavie C, Lippi G, Henry BM. Clinical features, laboratory characteristics, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19): Early report from the United States. Diagnosis. 2020;7(2):91–6.

https://doi.org/

10.1515/dx-2020-00466.Yang X, Yu Y, Xu J, Shu H, Xia Ja, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. 2020;8(5):475–81.

https://doi.org/

10.1016/S2213-2600(20)30079-57.Lai C-C, Shih T-P, Ko W-C, Tang H-J, Hsueh P-R. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. International Journal of Antimicrobial Agents. 2020;55(3):105924.

https://doi.org/

10.1186/s13000-020-01017-88.Zu ZY, Jiang MD, Xu PP, Chen W, Ni QQ. Coronavirus Disease 2019 (COVID-19): A Perspective from China. 2020;296(2):E15–e25.

https://doi.org/

10.1148/radiol.20202004909.Wang Y, Wang Y, Chen Y, Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures. Journal of medical virology. 2020;92(6):568–76.

https://doi.org/

10.1002/jmv.25748. Epub 2020 Mar 29

10. Zhang J-j, Cao Y-y, Tan G, Dong X, Wang B-c, Lin J, et al. Clinical, radiological, and laboratory characteristics and risk factors for severity and mortality of 289 hospitalized COVID-19 patients. Allergy. 2020;n/a(n/a).

https://doi.org/

10.1111/all.1449611.Lippi G, Wong J, Henry BM. Hypertension in patients with coronavirus disease 2019 (COVID-19): a pooled analysis. Polish archives of internal medicine. 2020;130(4):304–9.

https://doi.org/

10.20452/pamw.1527212.Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet (London, England). 2020;395(10229):1054–62.

https://doi.org/

10.1016/S0140-6736(20)30566-3. Epub 2020 Mar 11.13.Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, et al. Kidney impairment is associated with in-hospital death of COVID-19 patients. MedRxiv. 2020.

https://doi.org/

10.1101/2020.02.18.2002324214.Onder G, Rezza G, Brusaferro S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. 2020.

https://doi.org/

10.1001/jama.2020.468315.Fan Z, Chen L, Li J, Cheng X, Yang J, Tian C, et al. Clinical Features of COVID-19-Related Liver Functional Abnormality. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2020;18(7):1561–6.

https://doi.org/

10.1016/j.cgh.2020.04.002

16.Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. The Lancet Infectious Diseases. 2020.

https://doi.org/

10.1016/S1473-3099(20)30198-517.Sun Y, Dong Y, Wang L, Xie H, Li B, Chang C, et al. Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience. J Autoimmun. 2020;112:102473–.

https://doi.org/

10.1016/

j.jaut

.2020.102473

18.Zhao W, Zhong Z, Xie X, Yu Q, Liu J. Relation Between Chest CT Findings and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study. AJR American journal of roentgenology. 2020;214(5):1072–7.

https://doi.org/

10.2214/AJR.20.2297619.Pan Y, Guan H, Zhou S, Wang Y, Li Q, Zhu T, et al. Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China. 2020;30(6):3306–9.

https://doi.org/

10.1007/s00330-020-06731-x20.Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun. 2020;109:102433.

https://doi.org/

10.1016/

j.jaut

.2020.10243321.Morgan O. How decision makers can use quantitative approaches to guide outbreak responses. Philosophical transactions of the Royal Society of London Series B, Biological sciences. 2019;374(1776):20180365.

https://doi.org/

10.1098/rstb.2018.036522.Jian-ya G. Clinical characteristics of 51 patients discharged from hospital with COVID-19 in Chongqing, China. medRxiv. 2020.

https://doi.org/

10.1101/2020.02.20.2002553623.Yang W, Cao Q, Qin L, Wang X, Cheng Z, Pan A, et al. Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city, Zhejiang, China. Journal of Infection. 2020.

https://doi.org/

10.1016/

j.jinf

.2020.02.01624.Brüssow H. The novel coronavirus–a snapshot of current knowledge. Microbial Biotechnology. 2020;13(3):607–12.

https://doi.org/

10.1111/1751-7915.13557

25.Angeli F, Spanevello A, De Ponti R, Visca D, Marazzato J, Palmiotto G, et al. Electrocardiographic features of patients with COVID-19 pneumonia. European Journal of Internal Medicine. 2020;78:101–6.

https://doi.org/

10.1016/

j.ejim

.2020.06.01526.Wu J, Li W, Shi X, Chen Z, Jiang B, Liu J, et al. Early antiviral treatment contributes to alleviate the severity and improve the prognosis of patients with novel coronavirus disease (COVID-19). Journal of Internal Medicine. 2020;288(1):128–38.

https://doi.org/

10.1111/joim.1306327.Aggarwal S, Garcia-Telles N, Aggarwal G, Lavie C, Lippi G, Henry BM. Clinical features, laboratory characteristics, and outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19): Early report from the United States. Diagnosis (Berlin, Germany). 2020;7(2):91–6.

https://doi.org/

10.1515/dx-2020-004628.Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. The New England journal of medicine. 2020;382(18):1708–20.

https://doi.org/

10.1056/NEJMoa2002032

29.Cattaruzza MS, Zagà V, Gallus S, D'Argenio P, Gorini G. Tobacco smoking and COVID-19 pandemic: old and new issues. A summary of the evidence from the scientific literature. Acta Bio Medica Atenei Parmensis. 2020;91(2):106–12.

https://doi.org/

10.23750/abm.v91i2.969830.Vardavas CI, Nikitara K. COVID-19 and smoking: A systematic review of the evidence. Tob Induc Dis. 2020;18:20–.

https://doi.org/

10.18332/tid/11932431.Tan L, Wang Q, Zhang D, Ding J, Huang Q, Tang YQ, et al. Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study. Signal transduction and targeted therapy. 2020;5(1):33.

https://doi.org/

10.1038/s41392-020-0148-432.Xiong Y, Sun D, Liu Y, Fan Y, Zhao L, Li X, et al. Clinical and High-Resolution CT Features of the COVID-19 Infection: Comparison of the Initial and Follow-up Changes. Invest Radiol. 2020;55(6):332–9.

https://doi.org/

10.1097/RLI.000000000000067433. Rivera-Izquierdo M, del Carmen Valero-Ubierna M, R-delAmo JL, Fernández-García MÁ, Martínez-Diz S, Tahery-Mahmoud A, et al. Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study. PloS one. 2020;15(6):e0235107.

https://doi.org

10.1371/journal.pone.023510734.Wan S, Xiang Y, Fang W, Zheng Y, Li B, Hu Y, et al. Clinical features and treatment of COVID-19 patients in northeast Chongqing. Journal of Medical Virology. 2020;92(7):797–806.

https://doi.org/

10.1002/jmv.2578335.Wang K, Zuo P, Liu Y, Zhang M, Zhao X, Xie S, et al. Clinical and laboratory predictors of in-hospital mortality in patients with COVID-19: a cohort study in Wuhan, China. Clinical infectious diseases. 2020.

https://doi.org/

10.1093/cid/ciaa53836.Yang M, Ng MHL, Li CK. Thrombocytopenia in patients with severe acute respiratory syndrome (review). Hematology. 2005;10(2):101–5.

https://doi.org/

10.1080/1024533040002617037.Bi X, Su Z, Yan H, Du J, Wang J, Chen L, et al. Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count. Platelets. 2020;31(5):674–9.

https://doi.org/

10.1080/09537104.2020.1760230

clinical and paraclinical manifestations of hospitalized patients with covid-19

...

Yekefallah

et.al

clinical and paraclinical manifestations of hospitalized patients with covid-19

...

Yekefallah

et.al

PAGE \* MERGEFORMAT 29

Caring Today, Volume 1

, Issue 1, 202

5 PAGE \* MERGEFORMAT 28